Abstracts Archive - Page 23 of 2425 - ACR Meeting Abstracts

Abstract Number: 0272 • ACR Convergence 2024
Calcifications of the Transverse Ligament of the Atlas in Patients Diagnosed with Calciumpyrophosphate Crystal Arthritis – a Retrospective Observational Study
Shay Brikman¹, Noga Shabshin² and Amir Bieber³, ¹Emek Medical Center, Afula, Israel, ²Emek Medical Center, Clalit Health Services, Afula, Israel, ³Emek Medical Center, Clalit Health Services, Raanana, Israel
Background/Purpose: Chondrocalcinosis (CC) is commonly detected on X-ray films of the knee, wrist, and symphysis pubis. Calcium pyrophosphate (CPP) deposition disease is sometimes associated with…
Abstract Number: 0054 • ACR Convergence 2024
Supernatants from Macrophages Stimulated with Citrullinated and MAA-Modified Fibrinogen Contain PDGF-BB and TGF-b and Upregulate Fibrotic Markers in Human Lung Fibroblasts
Nozima Aripova¹, Michael Duryee¹, Bryant England¹, Carlos Hunter¹, Lauren Klingemann¹, Nigina Aripova², Amy Nelson¹, Jill Poole¹, Dawn Katafiasz¹, Kristina Bailey¹, Geoffrey Thiele¹ and Ted Mikuls¹, ¹University of Nebraska Medical Center, Omaha, NE, ²WUSTL, St. Louis, MO
Background/Purpose: Lung tissues from patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD) have greater levels of malondialdehyde-acetaldehyde adducts (MAA) that co-localize with citrullinated (CIT) and…
Abstract Number: 0077 • ACR Convergence 2024
Characteristics of Axial Spondyloarthritis in Patients with Onset Chronic Low Back Pain After Age 45
Fatma Zohra Yasmina Heddi¹, Zahira Lamri², kheireddine khelif², Amina Benammar² and wafa Zahdour², ¹Oran University Hospital, Rheumatology Department/ University of Oran 1, Faculty of Medicine, Oran, Oran, Algeria, ²Oran University Hospital, Rheumatology Department/ University of Oran 1, Faculty of Medicine, Oran, Algeria
Background/Purpose: The onset of axial spondyloarthritis (axSpA), as defined by the Assessment of SpondyloArthritis International Society (ASAS) criteria is unusual after the age of 45…
Abstract Number: 0340 • ACR Convergence 2024
Progressive Pulmonary Fibrosis Predicts Mortality in Myositis-Associated Interstitial Lung Disease
Yu-Wan Liao¹, Ming-Cheng Liu¹, Pin-Kuei Fu¹ and Wen-Nan Huang², and Integrated Care Center of Interstitial Lung Disease, ¹Taichung Veterans General Hospital, Taichung, Taiwan (Republic of China), ²Taichung Veterans General Hospital, Taichung, Taiwan, Taichung, Taiwan (Republic of China)
Background/Purpose: Myositis-associated interstitial lung disease (MA-ILD) is a complex condition with a variable prognosis and diverse clinical manifestations. The 2022 ATS/ERS/JRS/ALAT criteria for PPF provide…
Abstract Number: 0036 • ACR Convergence 2024
Deep Topic Modeling Deconvolves Cell States in Spatial Transcriptomic Profiles of Rheumatoid Arthritis Synovial Tissue
Preethi Periyakoil¹, Melanie Smith², Meghana Kshirsagar³, Daniel Ramirez⁴, Edward Dicarlo⁵, Susan Goodman⁶, Laura Donlin² and Christina Leslie⁷, ¹Weill Cornell Medical College, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Microsoft AI for Good, Seattle, ⁴Hospital for Special Surgery, Cartago, Costa Rica, ⁵Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ⁶Hospital for Special Surgery, New York 10025, NY, ⁷Memorial Sloan Kettering Cancer Center, New York, NY
Background/Purpose: Recent single-cell RNA sequencing (scRNA-seq) studies of the rheumatoid arthritis (RA) synovium have highlighted the heterogeneity of cell states present during active disease. It…
Abstract Number: 0324 • ACR Convergence 2024
Correlative Studies of CABA-201, a Fully Human, Autologous 4-1BB Anti-CD19 CAR T Cell Therapy in Patients with Immune-Mediated Necrotizing Myopathy and Systemic Lupus Erythematosus from the RESET-MyositisTM and RESET-SLETM Clinical Trials
Daniel Nunez¹, Jenell Volkov¹, Jason Stadanlick¹, Zachary Vorndran¹, Alexandra Ellis¹, Mallorie Werner¹, Justin Cicarelli¹, Jazmean Williams¹, Fatemeh Nezhad¹, Thomas Furmanak², Quynh Lam¹, Rebecca Estremera¹, Yvonne White¹, Jonathan Hogan¹, Claire Miller¹, Tahseen Mozaffar³, Saira Sheikh⁴, David Chang¹ and Samik Basu¹, ¹Cabaletta Bio, Philadelphia, PA, ²Cabaletta Bio - Philadelphia, PA, Philadelphia, PA, ³The University of California, Irvine, Orange, CA, ⁴University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: CD19 targeting chimeric antigen receptor (CAR) T cells have demonstrated durable drug-free responses and remission in patients with idiopathic inflammatory myopathies (IIM) and systemic…
Abstract Number: 0321 • ACR Convergence 2024
Diffusion Weighted Imaging in Muscle MRI Can Detect Quantitative Improvements in Muscle Edema: A Post-hoc Analyses of the Study of Tofacitinib in Refractory Dermatomyositis
Julie Paik¹, Patrick Debs², Anshula Nallapati¹, Lisa Christopher-Stine¹, Jemima Albayda³, Eleni Tiniakou⁴ and Laura Fayad², ¹Johns Hopkins University, Baltimore, MD, ²Johns Hopkins Radiology, Baltimore, MD, ³Johns Hopkins School of Medicine, Baltimore, MD, ⁴Johns Hopkins University, Lutherville Timonium, MD
Background/Purpose: Diffusion weighted imaging (DWI) in muscle magnetic resonance imaging is an underutilized, quantitative assessment tool in idiopathic inflammatory myopathies (IIM). It is not uncommon…
Abstract Number: 0290 • ACR Convergence 2024
Deucravacitinib Long-term Efficacy Through 4 Years in Week 16 Placebo Crossover Patients in the Phase 3 POETYK PSO-1, PSO-2, and LTE Program
Mark Lebwohl¹, Richard Warren², Shinichi Imafuku³, Jerry Bagel⁴, April W. Armstrong⁵, Thierry Passeron⁶, Subhashis Banerjee⁷, Renata M. Kisa⁸, Matthew J. Colombo⁷, Thomas Scharnitz⁸, Kim Hoyt⁸, Diamant Thaçi⁹ and Andrew Blauvelt¹⁰, ¹Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, ²Dermatology Centre, Northern Care Alliance NHS Foundation Trust and NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom, ³Fukuoka University Hospital Faculty of Medicine, Fukuoka, Japan, ⁴Psoriasis Treatment Center of New Jersey, East Windsor, ⁵University of California Los Angeles, Los Angeles, ⁶Université Côte d’Azur, University Hospital of Nice, Nice, France, ⁷Bristol Myers Squibb, Princeton, NJ, ⁸Bristol Myers Squibb, Princeton, ⁹Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Schleswig-Holstein, Germany, ¹⁰Oregon Medical Research Center, Portland, OR
Background/Purpose: Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, is approved in the US, EU, and other countries for treatment of adults with moderate…
Abstract Number: 0293 • ACR Convergence 2024
Assessment of Skin Cancer Risk in Autoimmune Diseases: A Multivariate Analysis Using a National Inpatient Database
Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY
Background/Purpose: Autoimmune diseases are known to be associated with an increased risk of many types of cancers. This study investigates the association between different types…
Abstract Number: 0318 • ACR Convergence 2024
The Relevance of a Positive ANA in New Patient Referrals to Rheumatology
Chi Chi Lau¹ and Ayesha Arif², ¹University of Vermont Medical Center, colchester, VT, ²University of Vermont Medical Center, Essex Junction, VT
Background/Purpose: A positive (+)ANA titer is a common reason for Rheumatology consultation, yet the ANA is a nonspecific, non-diagnostic, lab test that is positive in…
Abstract Number: 0200 • ACR Convergence 2024
Evaluating the Effectiveness of Educational Initiatives on Recruiting Underrepresented Participants into SLE Clinical Trials
Maria Bacalao¹, Marie Maitre² and Shivani Kottur³, ¹UT Southwestern, Dallas, TX, ²Parkland Hospital, Dallas, TX, ³UT Southwestern Medical Center, Dallas, TX
Background/Purpose: Healthcare disparities in SLE clinical trials are well known, with minoritized individuals facing more significant SLE morbidity and mortality, while being underrepresented in randomized…
Abstract Number: 0207 • ACR Convergence 2024
Investigation of Delays in Cancer Screening in RA
Rebecca Brooks¹, Cassondra Hulshizer², Andrew C. Hanson³, Vanessa Kronzer¹, John Davis¹, Elena Myasoedova¹ and Cynthia Crowson¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Utica, MN, ³Mayo Clinic, Rochester
Background/Purpose: Recent studies have shown that RA patients have increased mortality due to cancer. Despite the increased mortality, few studies have investigated the completion of…
Abstract Number: 0221 • ACR Convergence 2024
The Significance of Tenderness with or Without Swelling of Finger Joints in Relation to Magnetic-resonance-imaging, Ultrasound and X-ray in Psoriatic Arthritis
Victoria Furer¹, iris Eshed², Moshe iluz¹, Ori Elkayam³ and Ari Polachek⁴, ¹Tel-Aviv Medical Center, Tel-Aviv, Israel, ²Sheba Medical Center, Tel Hashomer affiliated with School of medicine, Tel Aviv University, Department of Diagnostic Imaging, Tel Aviv, Israel, ³Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁴Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel
Background/Purpose: The musculoskeletal involvement in psoriatic arthritis (PsA) can involve both articular and extra articular structures manifested by inflammatory and structural lesions. The relationship between…
Abstract Number: 0314 • ACR Convergence 2024
Microvascular Differences Between Acute and Chronic Cutaneous Graft versus Host Disease
Sehreen Mumtaz¹, Florentina Berianu², Benjamin Wang³, Breanna Cane⁴ and Olayemi Sokumbi⁴, ¹Mayo Clinic, Florida, Jacksonville, FL, ²mayo clinic, Ponte Vedra Beach, FL, ³Mayo Clinic, Jacksonville, FL, ⁴Mayo Clinic Florida, Jacksonville, FL
Background/Purpose: Cutaneous involvement in systemic sclerosis (SSc) and chronic sclerodermoid graft versus host disease (GVHD) is visibly indistinguishable and while characteristic nailfold videocapillaroscopy (NVC) patterns…
Abstract Number: 0317 • ACR Convergence 2024
Progressive Fibrosing Intersticial Lung Disease of Autoimmune Origin and Antifibrotic Medication: NEREA Registry
Pablo Moreno-Fresneda¹, Cristina Vadillo-Font², Fredeswinda Romero-Bueno³, Olga Sánchez-Pernaute⁴, Rosalía Laporta⁵, hildegarda Godoy Tundidor⁶, Belén López-Muñiz⁷, Laura Cebrián⁷, Claudia Valenzuela⁸, Irene Llorente-Cubas⁹, Jesús Loarce¹⁰, Juan Rigual¹⁰, Benjamin fernandez-Gutierrez¹¹, M Asuncion Nieto¹ and lydia Abasolo Alcazar¹², ¹Hospital Clínico San Carlos, Madrid, Madrid, Spain, ²Hospital Clinico S Carlos, Madrid, Spain, ³Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, ⁴Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, ⁵Hospital Universitario Puerta de Hierro, Madrid, Spain, ⁶Servicio de Reumatología, Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA , Madrid, Madrid, Spain, ⁷Hospital Universitario Infanta Leonor, Madrid, Spain, ⁸ILD Unit, Pulmonology Department, Hospital Universitario de la Princesa, University Autonomade Madrid, Madrid, Spain, Madrid, Madrid, Spain, ⁹Hospital Universitario de La Princesa, Madrid, Spain, ¹⁰Ramón y Cajal University Hospital, Madrid, Madrid, Spain, ¹¹HOSPITAL CLINICO SAN CARLOS, Madrid, Spain, ¹²IdISSC. HCSC, Madrid, Spain
Background/Purpose: Nintedanib and pirfenidone are approved therapies for the management of patients with progressive fibrosing interstitial lung diseases (ILD), including those of autoimmune origin (ILD…

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