ACR Meeting Abstracts

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  • Abstract Number: 0170 • ACR Convergence 2025

    Rheumatoid arthritis, serologic status and risk of heart failure: A national cohort study

    Seonyoung Kang1, Kyungdo Han2, Yeonghee Eun3, Jinhyung Jung4, Seulkee Lee1, Hoon-Suk Cha1, Jaejoon Lee5, Seonghye Kim1, Se Yun Kim6, Dong Wook Shin1 and Hyungjin Kim7, 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, 2Soongsil University, Seoul, Republic of Korea, 3Kangbuk Samsung Hospital, seoul, Republic of Korea, 4Sungkyunkwan University School of Medicine, Suwon, Republic of Korea, 5Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, 6Sungkyunkwan University, Seoul, Republic of Korea, 7Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Background/Purpose: Although rheumatoid arthritis (RA) is a known risk factor for heart failure (HF), a limited number of studies has explored the association based on…
  • Abstract Number: 0242 • ACR Convergence 2025

    Contemporary Recurrent Pericarditis Management – Real-world Evidence of Limited Cardiac Magnetic Resonance Imaging Prior to Initiating Rilonacept

    Brittany Weber1, Paul Cremer2, Michael Garshick3, Sushil Allen Luis4, Ajit Raisinghani5, Vidhya Parameswaran6, Allison Curtis6, Allan Klein7 and John Paolini6, 1Brigham and Women's Hospital, DEDHAM, MA, 2Cleveland Clinic, Shaker Heights, OH, 3NYU Langone Health, Tenafly, NJ, 4Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, 5Division of Cardiology, Department of Medicine, Sulpizio Cardiovascular Center, University of California San Diego, San Diego, CA, 6Kiniksa Pharmaceuticals, LEXINGTON, MA, 7Cleveland Clinic, Cleveland, OH

    Background/Purpose: Recurrent pericarditis (RP) is a chronic autoinflammatory disease (mediated by IL-1) that requires long-term treatment, and selection of therapy is guided by multiple factors.…
  • Abstract Number: 0230 • ACR Convergence 2025

    An Epic journey – Therapeutic Drug Monitoring at an Academic Center

    Puja Khanna1 and Michael Rice2, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Division of Gastroenterology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Non-oncologic use of immunomodulatory agents is increasing. These drugs have a narrow, patient-specific therapeutic index, making therapeutic drug monitoring essential for safe prescribing. However,…
  • Abstract Number: 0138 • ACR Convergence 2025

    Evaluating Artificial Intelligence for Diagnosing Antiphospholipid Syndrome in Pulmonary Embolism Case Reports: A Prompt-Based Analysis

    Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY

    Background/Purpose: Antiphospholipid syndrome (APS) is a complex autoimmune prothrombotic disorder that can present with venous or arterial thromboses, often masquerading as unprovoked pulmonary embolism (PE).…
  • Abstract Number: 0283 • ACR Convergence 2025

    The Performance of Rule-Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records

    Ana Valle1, Amy Vo2, Rochelle Castillo1, Yumeko Kawano3, Leah Santacroce3, Daniel Solomon4, Katherine Liao3 and Candace Feldman3, 1Brigham and Women's Hospital, Brookline, MA, 2Harvard Medical School, Boston, 3Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM; including dermatomyositis, polymyositis, and inclusion body myositis) are heterogenous systemic inflammatory conditions that cause significant disability and morbidity. The study…
  • Abstract Number: 0250 • ACR Convergence 2025

    Autoinflammatory diseases in adult patients. Spanish registry.

    Eztizen Labrador-Sanchez1, Diana Prieto-Peña2, Carlota L Iñiguez3, Rafael B. Melero-González4, Alberto Ruiz-Roman5, Clara Moriano6, Paula García-Escudero7, Anahy Maria Brandy8, Marta López9, Fred Anton Pages10, Maria Camila Osorio-SanJuan11, Nahia Plaza-Aulestia12, Bryan Josué Flores Robles13, Estibaliz Andres Trashaedo14 and Ricardo Blanco15, 1Hospital Universitario San Pedro, Laguardia, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Spain, 3Hospital del Bierzo, Ponferrada, Castilla y Leon, Spain, 4COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, 5Hospital Juan Ramon Jimenez, Huelva, Spain, 6Hospital León, LEON, Castilla y Leon, Spain, 7Hospital Universitario Álava, Bilbao, Spain, 8Hospital Germans Trias i Pujol, Badalona, Spain, 9Complex Hospitalari Universitari Moisés Broggi, Barcelona, Spain, 10Hospital General de Segovia, Segovia, Spain, 11Hospital Clínico Lozano Blesa, Zaragoza, Spain, 12Rheumatology division. Galdakao-Usansolo University Hospital, Galdakao, Spain, 13Hospital San Pedro, Logroño, Spain, 14Hospital San Pedro, Logroño, Spain, 15Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Autoinflammatory diseases(AIDs) are characterized by recurrent inflammatory episodes resulting from alterations in regulatory genes, activating the innate immune system. Although these diseases primarily occur…
  • Abstract Number: 0236 • ACR Convergence 2025

    Safety and Efficacy of T Cell Engager Therapy in patients with refractory Autoimmune Disease

    Laura Bucci1, Sebastian Böltz1, Melanie Hagen1, Danae-Mona Nöthling1, Tobias Rothe2, Carlo Tur1, Andreas Wirsching1, Janina Auth3, jochen wacker1, Markus Eckstein4, Stefano Alivernini5, Aline Bozec1, Christina Bergmann1, Maria Antonietta D'Agostino6, Maria Gabriella Raimondo1, Georg Schett7 and Ricardo Grieshaber-Bouyer8, 1Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, 2Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlagen, Germany, 3Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Bayern, Germany, 4Institute of Pathology and Comprehensive Cancer Center EMN, Friedrich-Alexander- Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, 5Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 6Division of Rheumatology and Clinical Immunology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 7Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany, 8University Hospital Erlangen, Erlangen, Germany

    Background/Purpose: T cell engagers (TCEs) are a promising therapeutic strategy to treat autoimmune diseases (AID). However, long-term data remain limited.Methods: Patients with treatment-refractory AID were…
  • Abstract Number: 0247 • ACR Convergence 2025

    Use of Nintedanib in Patients with Progressive Pulmonary Fibrosis

    Elizabeth Volkmann1, Steven Nathan2, Karen Coeytaux3, Yanni Fan4, Jill Curran3, Haikun Bao3, Kamila Sroka-Saidi5, Ann Chauffe6 and Jeffrey J Swigris7, 1Division of Rheumatology, Department of Medicine, University of California, David Geffen School of Medicine, Los Angeles, CA, USA, Los Angeles, CA, 2Inova Advanced Lung Disease and Transplant Program, Falls Church, VA, USA, Falls Church, 3Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA, Ridgefield, 4Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA, Ridgefield, CT, 5Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany, Ingelheim am Rhein, Germany, 6Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA, Newberry, FL, 7Center for Interstitial Lung Disease, Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA, Denver

    Background/Purpose: Nintedanib was approved in the US for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype (progressive pulmonary fibrosis [PPF])…
  • Abstract Number: 0279 • ACR Convergence 2025

    Assessment of Baseline IgG4-RD Disease Characteristics and Impact Upon Safety and Efficacy of Inebilizumab: Results from the MITIGATE Study

    Yoshiya Tanaka1, Emma Culver2, Arezou Khosroshahi3, Wen Zhang4, Kazuichi Okazaki5, Matthias Lohr6, nicolas schleinitz7, Xinxin Dong8, melissa rosen9, Sue Cheng8, Daniel Cimbora8 and John Stone10, 1University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2John Radcliffe Hospital; University of Oxford, Oxford, United Kingdom, 3Emory University, Atlanta, GA, 4Peking Union Medical College Hospital, Dong Cheng Qu, China (People's Republic), 5Kansai Medical University Kori Hospital, Osaka, Japan, 6Karolinska Institutet, Stockholm, Sweden, 7Aix Marseille university, AP-HM, Marseille, France, 8Amgen, Thousand Oaks, CA, 9Amgen Inc., Thousand Oaks, CA, 10Massachusetts General Hospital , Harvard Medical School, Concord, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a progressive, systemic, fibroinflammatory disease characterized by unpredictable and recurring flares, leading to organ damage and decreased quality of life.…
  • Abstract Number: 0260 • ACR Convergence 2025

    Development of a Consensus Definition of VEXAS Flare for Use in Clinical Research

    Lachelle D. Weeks1, Danielle Hammond2, Sinisa Savic3, Mael Heiblig4, Onima Chowdhury5, Arsène Mekinian6, Carmelo Gurnari7, Radhakrishanan Ramchandren8, Sophie georgin-Lavialle9, Marcela ferrada10, Sarah A. Buckley11, Bryan G. harder11, Sandra Goble11, David Beck12 and Matthew Koster13, 1Dana Farber Cancer Institute, Boston, MA, 2The University of Texas MD Anderson Cancer Center, Houston, TX, 3University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 4Lyon-Sud Hospital, Hospices Civils de Lyon, Paris and Université Claude Bernard, Lyon, France, 5Oxford University Hospitals’ NHS Foundation Trust and Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom, 6Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i3), Saint-Antoine University Hospital, 75012 Paris, France, Paris, France, 7Department of Biomedicine and Prevention, University of Rome Tor Vergata and Translational Hematology and Oncology Research Department, Taussig Cancer Center, Cleveland Clinic, Clevland, OH, Rome, Italy, 8University of Pittsburgh Medical Center, Pittsburgh, PA, 9Sorbonne university, Tenon hospital, DMU3ID, CEREMAIA, ERN RITA, Paris, France, 10University of Maryland, Bethesda, MD, 11Sobi Inc., Waltham, MA, 12Center for Human Genetics and Genomics, NYU Grossman School of Medicine. Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine. Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA, New York, NY, 13Mayo Clinic, Rochester, MN

    Background/Purpose: VEXAS syndrome is a recently identified, severe systemic hemato-inflammatory disease with a complex and heterogeneous clinical presentation. The disease is associated with significant morbidity…
  • Abstract Number: 0221 • ACR Convergence 2025

    A Multimodal Intervention Improves the Quantity and Quality of Disease Activity Measures Collection in a Multi-Centered National Rheumatoid Arthritis Network

    Grant Cannon1, Beth Wallace2, Deana Lazaro3, Pascale Schwab4, Paul Monach5, Ankoor Shah6, Gail Kerr7, Andreas Reimold8, Joshua Baker9, Gary Kunkel10, Katherine Wysham11, Liron Caplan12, John Richards13, Aleksander Lenert14, Andrew Jones15, Ted Mikuls16, Maria I. ("Maio") Danila17, Bryant England16, Brian Sauer18, Jorge Rojas19 and Isaac Smith20, 1University of Utah and Salt Lake City VA, Salt Lake City, UT, 2Michigan Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, 3VA New York Harbor Healthcare system, Short Hills, NJ, 4VA Portland and Oregon Health & Science University, Portland, OR, 5VA Boston Healthcare System, Boston, MA, 6Duke University, Durham, NC, 7Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, 8Dallas VA Medical Center, Dallas, TX, 9University of Pennsylvania, Philadelphia, PA, 10University of Utah and George E Wahlen VAMC, Salt Lake City, UT, 11VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 12Rocky Mountain Regional VAMC, Aurora, CO, 13Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, 14University of Iowa, Iowa City, IA, 15VA Saint Louis and Washington University, Saint Louis, 16University of Nebraska Medical Center, Omaha, NE, 17University of Alabama at Birmingham (UAB), Birmingham VA Medical Center, Birmingham, AL, 18Salt Lake City VA/University of Utah, Salt Lake City, UT, 19VA Puget Sound Health Care System, Seattle, WA, 20Duke University Hospital, Durham, NC

    Background/Purpose: Clinical guidelines recommend the use of disease activity measures (DAMs) in rheumatoid arthritis (RA) management. Measurement of DAMs is also a critical component of…
  • Abstract Number: 0240 • ACR Convergence 2025

    Behçet’s Disease in a Diverse Urban Single-Center Cohort in the United States: HLA-B Alleles and Clinical Features

    Amir Razmjou1, Alexandra Klomhaus2, David Kellner3, Meika Fang4, Michael Weisman5 and John FitzGerald3, 1UCLA / Veterans Affairs, Los Angeles, CA, 2UCLA, Los Angeles, 3UCLA, Los Angeles, CA, 4VA Greater Los Angeles/UCLA, Los Angeles, CA, 5Cedars-Sinai Medical Center, LOS ANGELES, CA

    Background/Purpose: Behçet’s disease (BD) is a chronic systemic disease with heterogenous clinical presentations. The strongest genetic risk factor and diagnostic biomarker for BD is the…
  • Abstract Number: 0271 • ACR Convergence 2025

    Clinical Presentation of Igg4-Related Disease. Multicenter Study and Literature Review

    Rafael Gálvez Sánchez1, Fernando Lopez Gutierrez2, Javier Loricera3, Pablo Martínez Calabuig4, Jorge Juan Fragío Gil5, Roxana González Mazario6, Cristina Hormigos Martin7, DALIFER FREITES8, Maria Rodriguez Laguna9, Patricia Moya Albarado10, Marta López i Gómez11, Hector Corominas12, Maite Silva-Diaz13, GUILLERMO GONZALEZ ARRIBAS14, Angel Garcia-Aparicio15, Judit Font-Urgelles16, Ivette Casafont-Solé16, elisabeth Castañeda17, Carolina Merino18, Raquel Zas19, Juan Molina-Collada20, Sergio Rodríguez Montero21, Rafael B. Melero-González22, Eva Galíndez Agirregoikoa23, Andrea Hernández24, Lucia Pantoja25, Ignacio Braña26, Vega Jovaní27, Elia Valls-Pascual28, Natalia Mena Vázquez29, Adela Gallego30, Noelia Cabaleiro Raña31, Raul Veroz32, Mariano Andrés Collado33, Santos Castañeda34 and Ricardo Blanco35, 1Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, Immunopathology Group -IDIVAL, Reumatología, Santander, Santander, Spain, 3Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 4Hospital General Universitario de Valencia, Spain/ Uversidad Catolica de Valencia San Vicente Martir, Valencia, Spain, Ontinyent, Spain, 5Hospital General Universitario, Valencia, Spain, 6Hospital General de Valencia, Valencia, Spain, 7Hospital Clínico San Carlos, Madrid, Spain, 8Rheumatology Service, San Carlos Clinical Hospital, Madrid, Madrid, Spain, 9Hospital Clinico San Carlos, Madrid, Spain, 10Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 11Hospital Universitario de Araba, Vitoria, Pais Vasco, Spain, 12Hospital de Sant Pau, Barcelona, Spain, 13Complexo Hospitalario Universitario A Coruña, A Coruña, Galicia, Spain, 14Facultativo especialista, PALMA DE MALLORCA, Galicia, Spain, 15Hospital Universitario de Toledo, Toledo, Spain, 16Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 17Hospital Universitario Infanta Sofía, Madrid, Madrid, Spain, 18Rheumatology department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Madrid, Spain, 19Hospital Universitario Doce de Octubre, Madrid, Spain, 20Department of Rheumatology, Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain, Madrid, Spain, 21Hospital Universitario de Valme, Sevilla, Andalucia, Spain, 22COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, 23BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 24Hospital Universitario de Gran Canaria Dr Negrin, Palmas de Gran Canaria, Canarias, Spain, 25Complejo Hospitalario Segovia, Segovia, Spain, 26Hospital Universitario Central de Asturias, Oviedo, Spain, 27Hospital General Universitario de Alicante, Reumatología, Alicante, Alicante, Comunidad Valenciana, Spain, 28Hospital General de Valencia, Valencia, Comunidad Valenciana, Spain, 29Hospital Regional Universitario de Malaga, Malaga, Spain, Málaga, Spain, 30Complejo Hospitalario don Benito Villanueva, Badajoz, Spain, 31Hospital Universitario Montecelo, Rheumatology, Pontevedra, Galicia, Spain, 32Hospital de Merida, Merida, Extremadura, Spain, 33Hospital General Universitario de Alicante, Madrid, Comunidad Valenciana, Spain, 34Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 35Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic fibroinflammatory entity that can involve almost every organ, with characteristic histological features. Its pathogenesis remains poorly understood, clinical…
  • Abstract Number: 0268 • ACR Convergence 2025

    Multicenter study and literature review of JAK inhibitor treatment in refractory uveitis due to different immune-mediated inflammatory pathologies

    Nuria Barroso Garcia1, Lara Sánchez Bilbao2, José Luis Martín-Varillas3, Vanesa Calvo-Río2, Mar Esteban Ortega4, Santiago muñoz Fernández5, José Luis Álvarez-Vega6, Emma Beltran7, Vega Jovaní8, Olga Maiz Alonso9, raúl Veroz González10, Angel Garcia-Aparicio11, marta Garijo Bufort12 and Ricardo Blanco2, 1Rheumatology, Hospital Regional Universitario, Universidad de Málaga UMA, Málaga, Spain, Malaga, Spain, 2Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain, 3Rheumatology Division, Hospital de Laredo. IDIVAL, Immunopathology Group. Santander, Spain., Laredo, Spain, 4Rheumatology and Ophthalmology. Hospital Infanta Sofía. Madrid. Spain, Madrid, Spain, 5Rheumatology and Ophthalmology. Hospital Infanta Sofía, Madrid. Spain, Madrid, 6Rheumatology. Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain., Badajoz, Spain, 7Rheumatology. Hospital del Mar. Barcelona, Spain., Barcelona, Spain, 8Hospital General Universitario de Alicante, Reumatología, Alicante, Alicante, Comunidad Valenciana, Spain, 9Rheumatology. Hospital de Donostia. San Sebastián, Spain., San Sebastián, Spain, 10Rheumatology. Hospital de Mérida. Mérida, Spain., Mérida, Spain, 11Hospital Universitario de Toledo, Toledo, Spain, 12Rheumatology Department, Hospital de Sagunto, Spain, Valencia, Spain

    Background/Purpose: Non-infectious uveitis may be related to several immune-mediated diseases (IMIDs). Those that are refractory to conventional therapy or biologics may lead to severe ocular…
  • Abstract Number: 0227 • ACR Convergence 2025

    Malignancy Screening of Dermatomyositis Patients in the Penn State Registry of Inflammatory Myopathies (PRIMO)

    Katrina Gonzales1, William DeKryger2, Deepika Pugalenthi Saravanan2, Esha Tulsian2, Peri Newman3, Jacob Colello2, Galen Foulke4 and Nancy Olsen5, 1Penn State College of Medicine, Hummelstown, PA, 2Penn State College of Medicine, Hershey, PA, 3Penn State Health/ Penn State College of Medicine, Hershey, PA, 4Penn State Health, Hershey, PA, 5Penn State University/Milton S Hershey, Hershey, PA

    Background/Purpose: Dermatomyositis (DM) is an immune-mediated myopathy characterized by muscle weakness and skin rash that carries an elevated risk of associated malignancy within 5 years…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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