Abstracts Archive - Page 2294 of 2607 - ACR Meeting Abstracts

Abstract Number: 2107 • 2013 ACR/ARHP Annual Meeting
Benefitial Effects Of a Simple Stretching Exercise Program For Patients With Ankylosing Spondylitis: A Randomized Controlled Trial
Andréa L. Gallinaro¹, Carla G.S. Saad¹, Claudia Goldenstein-Schainberg¹, Percival D sampaio-Barros¹, Julio C. B. Moraes¹, Hamilton Roschel², Ana Lucia S. Pinto¹ and Celio R. Gonçalves³, ¹Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ²Universidade de São Paulo, Faculdade de Educação Física e Esporte, São Paulo, Brazil, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Static and dynamic stretching exercises are applied in Ankylosing Spondylitis (AS) patients to preserve and restore the axial mobility. However, there are no data…
Abstract Number: 2108 • 2013 ACR/ARHP Annual Meeting
Pre- and Postoperative Physical Therapy In Total Hip and Knee Replacement Surgery: A Multi Center Study
Wilfred FH Peter^1,2, Claire Tilbury³, Rutger Tordoir⁴, Suzan Verdegaal⁵, Ron Onstenk⁶, Menno Benard⁷, Stephan Vehmeijer⁸, Enrike van der Linden-van der Zwaag¹, Eric Vermeulen¹, Rob Nelissen¹ and Thea VlietVlieland⁹, ¹Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands, ²Reade, center for rehabilitation and rheumatology, Amsterdam, Nicaragua, ³Departement of Orthopedics, Leiden University Medical Center, Leiden, Netherlands, ⁴Departement of orthopedics, Rijnland Hospital, Leiderdorp, Netherlands, ⁵Departement of Orthopedics, Rijnland Hospital, Leiderdorp, Netherlands, ⁶Department of Orthopedics, Het Groene Hart Hospital, Gouda, Netherlands, ⁷Departement of Orthopedics, Reinier de Graaf Hospital, Delft, Netherlands, ⁸Department of Orthopedics, Reinier de Graaf Hospital, Delft, Netherlands, ⁹Department of Orthopaedics, Leids University Medical Center, Leiden, Netherlands
Background/Purpose: Physical therapy shown to be effective after Total Hip and Knee Arthroplasty. Less evidence is available for preoperative physical therapy in Total Hip and…
Abstract Number: 2069 • 2013 ACR/ARHP Annual Meeting
Serum Interferon-α Is a Biomarker To Reflect The Disease Activity In Patients With Anti-Melanoma Differentiation-Associated Gene 5 (MDA5) Antibody-Positive Dermatomyositis
Yoshiro Horai¹, Tomohiro Koga², Keita Fujikawa³, Ayuko Takatani⁴, Ayako Nishino¹, Yoshikazu Nakashima⁵, Takahisa Suzuki⁵, Shin-ya Kawashiri¹, Naoki Iwamoto⁵, Kunihiro Ichinose⁶, Mami Tamai⁵, Hideki Nakamura⁵, Hiroaki Ida⁷, Yuji Ishimatsu⁸, Hiroshi Mukae⁹, Yasuhito Hamaguchi¹⁰, Manabu Fujimoto¹¹, Masataka Kuwana¹², Tomoki Origuchi¹³, Shigeru Kohno⁸ and Atsushi Kawakami⁵, ¹Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Departments of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Arthritis and Connective Tissue Disease, Isahaya Health Insurance General Hospital, Isahaya, Japan, ⁴Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁶Department of Immunology and Rheumatology, Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁷Department of Internal Medicine, Division of REspirology, Neurology and Rheumatology, Kurume University School of Medicine, Kurume, Japan, ⁸Department of Molecular Microbiology and Immunology, Nagasaki University School of Medicine, Nagasaki, Japan, Nagasaki, Japan, ⁹Department of Respiratory Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, Kitakyushu, Japan, ¹⁰Department of Dermatology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, ¹¹Dermatology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, ¹²Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ¹³Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Background/Purpose: The pathogenesis of anti-melanoma differentiation-associated gene 5 (MDA5) antibody (Ab)-positive dermatomyositis (DM), which often complicates rapidly progressive interstitial lung disease (RPILD), is thought to…
Abstract Number: 2070 • 2013 ACR/ARHP Annual Meeting
Cytokine Profiles In Polymyositis and Dermatomyositis Complicated With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Associated Interstitial Lung Disease Or Anti-Aminoacyl tRNA Synthetase Antibody-Associated Interstitial Lung Disease
Takahisa Gono, Yasushi Kawaguchi, Hirotaka Kaneko, Yasuhiro Katsumata, Masanori Hanaoka, Sayuri Kataoka, Hidenaga Kawasumi, Kae Takagi, Hisae Ichida, Sayumi Baba, Yuko Okamoto, Yuko Ota and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan
Background/Purpose: Polymyositis (PM) / dermatomyositis (DM) are often complicated with interstitial lung disease (ILD). In PM/DM, complication with ILD is associated with anti-aminoacyl-tRNA synthetase (ARS),…
Abstract Number: 2071 • 2013 ACR/ARHP Annual Meeting
Adipokines Contribute To The Inflammatory Response In Adult and Juvenile Myositis
Molly S. Hein¹, Cynthia S. Crowson², Helen Khun², Consuelo Lopez de Padilla³, Erik J. Peterson⁴, Emily Baechler⁵ and Ann M. Reed¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ³Rheumatology/Immunology Research, Mayo Clinic, Rochester, MN, ⁴Medicine/Rheumatic and Autoimmune Diseases, University of Minnesota Medical School, Minneapolis, MN, ⁵Medicine, University of Minnesota, Minneapolis, MN
Background/Purpose: Recently adipokines have been implicated for their role in regulating immune and inflammatory responses in autoimmune disease. To test the hypothesis that adipokines are…
Abstract Number: 2072 • 2013 ACR/ARHP Annual Meeting
Decreased Number Of Circulating NK Cells and Dramatic Lack Of IFN-Gamma Production In Patients With Antisynthetase Syndrome
Baptiste Hervier^1,2, Yves Allenbach^3,4, Fleur Cohen-Aubart⁵, Micheline Pha⁶, Lenaig Mescam-Mancini⁷, David Saadoun⁸, Alexis Mathian^5,6, Olivier Benveniste^9,10 and Vincent Vieillard¹, ¹INSERM UMR-S 1135, UPMC, Paris, France, ²Internal Medicine & Clinical Immunology Dpt, Pitié-Salpêtrière Hospital, APHP, Paris, France, ³Internal Medicine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁴INSERM UMR974, UPMC, Paris, France, ⁵Internal Medicine Dpt 2, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁶INSERM UMR-S 945, UPMC, Paris, France, ⁷Pathology Dpt, University hospital, Grenoble, France, ⁸DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France, ⁹UMR 974, Sorbonne Universités, University Pierre et Marie-Curie-Paris 6, INSERM, Paris, France, ¹⁰Internal Medecine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France
Background/Purpose: Antisynthetase syndrome (ASS) is a rare autoimmune myositis associated with interstitial lung disease (ILD) and characterized by specific anti-tRNA-synthetase autoantibodies (ARS). To date, the…
Abstract Number: 2073 • 2013 ACR/ARHP Annual Meeting
Clinical and Prognostic Factors Associated With Survival In Mexican Patients With Idiopathic Inflammatory Myopathies
Angeles Shunashy Galindo-Feria¹, Jorge Rojas-Serrano² and Andrea Hinojosa-Azaola¹, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Interstitial Lung Diseases Unit, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico
Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune diseases, with low prevalence and 5-year survival of 70-95%. Previous studies in Mexican IIM…
Abstract Number: 2074 • 2013 ACR/ARHP Annual Meeting
The Analysis Of Prognostic Factors In Patients With Inflammatory Myopathies and Amyopathic Dermatomiositis Complicated With Interstitial Lung Disease
Maasa Hama¹, Yumiko Sugiyama¹, Yohei Kirino¹, Yosuke Kunishita¹, Daiga Kishimoto¹, Reikou Kamiyama¹, Kaoru Minegishi¹, Ryusuke Yoshimi¹, Yukiko Asami¹, Atsuhisa Ueda¹, Mitsuhiro Takeno¹, Ichiro Aoki² and Yoshiaki Ishigatsubo¹, ¹Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ²Department of Molecular Pathology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
Background/Purpose: Because interstitial lung disease (ILD) is one of the most critical manifestations and can be lethal in inflammatory myopathies (IM), especially amyopathic dermatomiositis (ADM),…
Abstract Number: 2075 • 2013 ACR/ARHP Annual Meeting
Analysis Of The Associations Between Serum Ferritin and Cytokines In Pulmonary Disease Activity With Polymyositis/Dermatomyositis
Hidenaga Kawasumi, Takahisa Gono, Yasushi Kawaguchi, Yasuhiro Katsumata, Masanori Hanaoka, Sayuri Kataoka, Kae Takagi, Hisae Ichida, Sayumi Baba, Yuko Okamoto, Yuko Ota and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan
Background/Purpose: Polymyositis (PM) / dermatomyositis (DM) is occasionally complicated by interstitial lung disease (ILD), and ILD is a prognostic factor in PM/DM. We previously reported…
Abstract Number: 2076 • 2013 ACR/ARHP Annual Meeting
Oxidation Products Of Arachidonic Acid and Linoleic Acid Are Increased In High Density Lipoprotein From Patients With Dermatomyositis and Polymyositis
Christina Charles-Schoeman¹, Yuen Yin Lee¹, Ani Shahbazian¹, David Meriwether², Geraldine Navarro¹, John D. FitzGerald¹ and Srinivasa T. Reddy², ¹Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²Medicine-Cardiology, UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Oxidation products of arachidonic acid and linoleic acid including hydroxyeicosatetraenoic acids (HETEs) and hydroxyoctadecadienoic acids (HODEs), respectively, play an important role in the…
Abstract Number: 2077 • 2013 ACR/ARHP Annual Meeting
Inflammatory Lung Disease a Potential Risk Factor For Onset Of Inflammatory Myopathies
Ingrid E. Lundberg¹, Sevim Barbasso Helmers² and Lars Alfredsson³, ¹Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, ²Institute of Environmental Medicine, Unit of Cardiovascular Epidemiology, Karolinska Institutet, Stockholm, Sweden, ³Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Although the etiology of inflammatory myopathies is unclear, there are data indicating that myositis occurs as a result of complex interactions between genes and…
Abstract Number: 2078 • 2013 ACR/ARHP Annual Meeting
Pulmonary Hypertension In Anti-Jo1 Syndrome
Nilofar Syed¹, Ruchi Yadav², Colin O'Rourke³ and Soumya Chatterjee⁴, ¹Rheumatology, Cleveland Clinic, Cleveland, OH, ²Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, ³Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ⁴Rheumatic and Immunologic Ds, Cleveland Clinic, Cleveland, OH
Background/Purpose: Antisynthetase syndrome is characterized by fever, myositis, interstitial lung disease (ILD), inflammatory arthritis, mechanic's hands, and Raynaud phenomenon. The most commonly reported form of…
Abstract Number: 2079 • 2013 ACR/ARHP Annual Meeting
Serum Interferon α, β and Interleukin-18 Are Associated With Disease Activity Of Rapidly Progressive Interstitial Lung Disease In Patients With Clinical Amyopathic Dermatomyositis
Shinji Sato¹, Noriko Sasaki¹, Shinichi Nogi¹, Naofumi Chinen², Kiri Honda¹, Eiko Saito¹, Chiho Yamada² and Yasuo Suzuki², ¹Rheumatology, Tokai University School of Medicine, Isehara, Japan, ²Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan
Background/Purpose: It is well known that rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM) is associated with poor outcome. Previous findings suggested…
Abstract Number: 2080 • 2013 ACR/ARHP Annual Meeting
Pregnancy Outcomes In Adult Patients With Dermatomyositis and Polymyositis
Lorinda Chung¹, David Fiorentino², Shufeng Li³ and Eliza Chakravarty⁴, ¹Rheumatology, Stanford Univ Medical Center, Palo Alto, CA, ²Dermatology, Stanford University School of Medicine, Redwood City, CA, ³Dermatology, Stanford University School of Medicine, Palo Alto, CA, ⁴Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Dermatomyositis (DM) and polymyositis (PM) are autoimmune inflammatory myopathies that frequently affect females of child-bearing potential. Small studies have indicated that active disease during…
Abstract Number: 2081 • 2013 ACR/ARHP Annual Meeting
Role Of Muscle Persistent CD28null T Cells In Glucocorticoid Therapy Resistance In Myositis Patients
Jayesh Pandya¹, Ingela M. Loell², Mohammad Shahadat Hossain², Mei Zong², Sukanya Raghavan², Ingrid E. Lundberg³ and Vivianne Malmström², ¹Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, ²Rheumatology Unit, Department of Medicine, Karolinska University Hospital in Solna, Karolinska Institutet, Stockholm, Sweden, ³Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Polymyositis (PM) and dermatomyositis (DM) are characterized by infiltration of T cells and macrophages in skeletal muscle tissue. Conventional immunosuppressive treatment has limited effects…

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