ACR Meeting Abstracts

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  • Abstract Number: 1958 • 2012 ACR/ARHP Annual Meeting

    Bone Mineral Density in Lupus Erythematosus Women One Year After Rituximab Therapy

    Claudia Mendoza-Pinto1, Mario Garcia-Carrasco1, Mario Jiménez-Hernández1, Alma Rodríguez-Gallegos2, Socorro Méndez-Martínez1 and Aurelio Lopez-Colombo3, 1Systemic Autoimmune Disease, HGR 36 CMN Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico, 2Laboratorios Clínicos de Puebla, Puebla, Mexico, 3Research Departament, Delegación Estatal, Instituto Mexicano del Seguro Social, Puebla, Mexico

    Background/Purpose: Low bone mineral density (BMD) and osteoporosis may be significant complications in patients with systemic lupus erythematosus (SLE). Recent studies have shown that biologic therapy could…
  • Abstract Number: 1919 • 2012 ACR/ARHP Annual Meeting

    Regulatory T Cells in IgG4-Related Disease Patients Presenting with Sclerosing Sialadenitis and Dacryoadenitis

    Winnie K. Pang1, Ya Liu2, Julie Wang2, Song Guo Zheng2, Kiran Qidwai3, Russell K. Brynes3 and Francisco P. Quismorio Jr.1, 1Rheumatology, University of Southern California Keck School of Medicine, Los Angeles, CA, 2Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, 3Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA

    Background/Purpose: IgG4-Related Disease (IgG4-RD) is characterized by inflammation and fibrosis of various organ systems. Its diverse clinical presentations include autoimmune pancreatitis, retroperitoneal fibrosis, sialadenitis, and…
  • Abstract Number: 1920 • 2012 ACR/ARHP Annual Meeting

    Spectrum of IgG4-Related Disease and Diagnostic Value of Serum IgG4 Determinations

    Emma Kotisalmi1, Tom Pettersson2, Aaro Miettinen3, Johanna Arola4 and Martti Färkkilä5, 1Department of Medicine, University of Helsinki, Helsinki, Finland, 2Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland, 3Department of Immunology, Huslab, Helsinki, Finland, 4Department of Pathology, University of Helsinki and Huslab, Helsinki, Finland, 5Department of Gastroenterology, Helsinki University Central Hospital, Helsinki, Finland

    Background/Purpose: IgG4-related disease is a recently described systemic inflammatory and fibrosing condition that may mimic various other systemic rheumatic diseases. We studied the occurrence of…
  • Abstract Number: 1921 • 2012 ACR/ARHP Annual Meeting

    Diagnostic Utility of Serum IgG4 in IgG4-Related Disease

    Mollie Carruthers1, Tamara Augustin2, John H. Stone1 and Arezou Khosroshahi1, 1Rheumatology, Massachusetts General Hospital, Boston, MA, 2Internal Medicine, Internal Medicine, Northshore Medical Center, Salem, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a recently recognized fibro-inflammatory disease with multi-organ system involvement, often but not always characterized by elevated serum IgG4 concentrations. The…
  • Abstract Number: 1922 • 2012 ACR/ARHP Annual Meeting

    Articular Involvement in Relapsing Polychondritis: A Case Series

    Laura O. Damian1, Linda Ghib2, Ioana Felea1, Alma Maniu3, Nadia Radics2, Simona Falaus2, Ileana Filipescu4, Siao-pin Simon5 and Simona Rednic6, 1Rheumatology, Emergency Clinical County Hospital Cluj, Cluj-Napoca, Romania, 2Rheumatology, Emergency County Clinical Hospital Cluj Napoca, Cluj Napoca, Romania, 3Otorhynolaringology, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Cluj Napoca, Romania, 4Rheumatology, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Cluj-Napoca, Romania, 5Rheumatology, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Cluj Napoca, Romania, 6Clinical County Emergency Hospital, Cluj-Napoca, Romania

    Background/Purpose: Relapsing polychondritis (RP) is a relatively rare, but progressive disease with predilection for cartilage, with few data available regarding the arthritis in this setting.…
  • Abstract Number: 1923 • 2012 ACR/ARHP Annual Meeting

    Biologics in Relapsing Polychondritis: A Single Center Case-Series

    Guillaume Moulis1, Laurent Sailler2, Grégory Pugnet3, Leonardo Astudillo2 and Philippe Arlet1, 1Department of Internal Medicine, Toulouse University Hospital, University of Toulouse, Toulouse, France, 2Department of Internal Medicine, Toulouse University Hospital, Toulouse, France, 3Department of Internal Medicine, Toulouse University Hospital, University of Toulouse, INSERM UMR 1027, Toulouse, France

    Background/Purpose: First-line treatment for relapsing polychondritis (RP) is costicosteroids (CS). Dapsone and methotrexate have been proposed as second-line therapies. Only few reports have been published…
  • Abstract Number: 1924 • 2012 ACR/ARHP Annual Meeting

    What Do Patients with Polmyalgia Rheumatica Mean When They Describe Stiffness? A Qualitative Study

    Rodney A. Hughes1, Sarah Mackie2, John R. Kirwan3, Colin T. Pease4, Margaret Walsh1 and Marianne Morris5, 1Rheumatology, St. Peters Hospital, Chertsey Surrey, United Kingdom, 2Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, 3Academic Rheumatology Unit, Bristol Royal Infirmary, Bristol, United Kingdom, 4Department of Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5University of the West of England, Bristol, United Kingdom

    Background/Purpose: Patients with PMR report significant symptoms of pain and stiffness.  Stiffness has usually been included in diagnostic criteria for PMR but has never been…
  • Abstract Number: 1925 • 2012 ACR/ARHP Annual Meeting

    Patient Satisfaction and Experience with Golimumab, Adalimumab, and Etanercept for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis

    Susan Bolge1, Helen Eldridge2, Dilesh Doshi1, Lorie Ellis3, Barbara Roland4 and John Woelfel4, 1Janssen Scientific Affairs, LLC, Horsham, PA, 2Janssen Services, LLC., Titusville, NJ, 3Health Economics & Outcomes Research, Janssen Scientific Affairs, LLC, Horsham, PA, 4The Dominion Group, Reston, VA

    Title:  Patient Satisfaction and Experience with Golimumab, Adalimumab, and Etanercept for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis Background/Purpose: Golimumab (GLM), adalimumab…
  • Abstract Number: 1926 • 2012 ACR/ARHP Annual Meeting

    Evaluation of Strategies to Taper Anti-TNF Drugs in Patients with Inflammatory Rheumatic Disease (Rheumatoid Arthritis, Ankyloing Spondylitis, Psoriatic Arthritis, Adult-age Juvenile Idiopatic Arthritis) in Long-Term Remission

    Jakub Zavada1, Katarina Hviscova2, Katerina Jarosova2, Sarka Forejtova3, Jiri Stolfa2, Liliana Sedova2, Dana Tegzova2, Jiri Vencovsky2 and Karel Pavelka2, 1Charles University, Prague, Czech Republic, 2Institute of Rheumatology, Prague, Czech Republic, 3Institute of Rheumatology, Prague, Prague, Czech Republic

    Background/Purpose:   While abrupt discontinuation strategies of anti-TNF drugs have been shown to result in frequent disease flares, tapering of dose may be a feasible…
  • Abstract Number: 1927 • 2012 ACR/ARHP Annual Meeting

    Inflammatory Meningeal Involvement in Patients with Rheumatic Diseases Responsive to Rituximab

    Jane Park1, Eyal Kedar1, Ingeborg Sacksen1, John Henson2 and Gregory C. Gardner3, 1Rheumatology, University of Washington, Seattle, WA, 2Neurology, Swedish Neuroscience Institute, Seattle, WA, 3Medicine/Rheumatology, University of Washington, Seattle, WA

    Background/Purpose: Inflammatory meningeal involvement can be idiopathic or associated with a variety of inflammatory rheumatic diseases such as ANCA associated vasculitis (AAV), rheumatoid (RA) arthritis,…
  • Abstract Number: 1928 • 2012 ACR/ARHP Annual Meeting

    Evaluating the Therapeutic Effects of B Cell Depletion Therapy with Rituximab in a Longitudinal Cohort of Mixed Connective Tissue Disease Patients

    Ragnar Gunnarsson1, Inge-Margrethe Gilboe1, Torhild Garen2 and Øyvind Molberg3, 1Rheumatology unit, Oslo University Hospital Rikshospitalet, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 3Oslo University Hospital, Oslo, Norway

    Background/Purpose: Even though 40 years have passed since MCTD was defined as a distinct disorder, there is still no evidence based therapy available. The choice…
  • Abstract Number: 1929 • 2012 ACR/ARHP Annual Meeting

    Pernicious Anemia and Vitamin B-12 Deficiency in Autoimmune Disease:  Neglecting the Feet Will Lead You Astray

    Michael R. Lovy, Desert Oasis Healthcare, Palm Springs, CA

    Background/Purpose:  The occurrence of multiple autoimmune disorders in individual patients is commonly observed.  Rarely, this is explained by recently recognized genetically based autoimmune polyendocrine syndromes.…
  • Abstract Number: 1930 • 2012 ACR/ARHP Annual Meeting

    Progranulin Plays a Protective Role in the Pathogenesis of Inflammatory Bowel Disease

    Fanhua Wei1, Jinlong Jian1, Yuying Zhang1, Jiqiang Lin1, Juan Lafaille2, Michael Dustin3, Lloyd Mayer4 and Chuanju Liu1, 1Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY, 2New York University School of Medicine, New York, NY, 3Skirball Inst Fl 2 Labs 4 & 5, NYU School of Medicine, New York, NY, 4Div of Clinical Immunology, Mount Sinai Medical Center, New York, NY

    Background/Purpose: Progranulin (PGRN) is a growth factor with multiple functions. We recently reported that PGRN and its derived engineered protein Atsttrin directly bound to TNF…
  • Abstract Number: 1931 • 2012 ACR/ARHP Annual Meeting

    Influence of Trough Serum Drug Level and Immunogenicity On the Lack of Response to Adalimumab Therapy in Inflammatory Bowel Disease Patients

    Shui Long Wang1, Scott Hauenstein1, Linda Ohrmund1, Reshma Shringarpure2, Douglas C. Wolf3, Isam A. Diab4, Jared Salbato1, Rukmini Reddy1, Kevin McCowen1, Shawn Shah1, Steven Lockton1, Emil Chuang2 and Sharat Singh1, 1Research and Development, Prometheus Laboratories, San Diego, CA, 2Clinical and Medical Affairs, Prometheus Laboratories, San Diego, CA, 3Atlanta Gastroenterology Associates, Atlanta, GA, 4Paramount Medical Research & Consulting, Middleburg Heights, OH

    Background/Purpose: Anti-TNF-α therapy is effective for the treatment of inflammatory bowel disease (IBD). Nevertheless, over 30% of IBD patients fail to respond to anti-TNF-α therapy…
  • Abstract Number: 1932 • 2012 ACR/ARHP Annual Meeting

    Clinical Features of an Aromatase Inhibitor Associated Syndrome Presenting As Rheumatoid Arthritis Ronald J. Anderson, MD, Brigham &Women’s Hospital

    Ronald J. Anderson, Rheumatology/Admin B-3, Brigham & Womens Hospital, Boston, MA

    Background/Purpose: The aromatase inhibitors (AI); anastrozole, letrozole and exemestane are used in the treatment of postmenopausal women with estrogen receptor positive breast cancer. Arthralgias occur…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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