ACR Meeting Abstracts

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  • Abstract Number: 2019 • 2012 ACR/ARHP Annual Meeting

    A Novel MRI Scoring System for the Evaluation of Early-Stage Disease Activity of the Wrist in Juvenile Idiopathic Arthritis

    Charlotte M. Nusman1, Robert Hemke1, Taco W. Kuijpers2, Eline E. Deurloo1, Dieneke Schonenberg3, J. Merlijn Van den Berg4, Koert M. Dolman5, Marion A.J. Van Rossum4 and Mario Maas1, 1Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 2Pediatric Rheumatology and Immunology, Emma Children's Hospital/Academic Medical Center (AMC), Amsterdam, Netherlands, 3Department of Pediatric Rheumatology and Immunology, Emma Children's Hospital / Academic Medical Center (AMC), Amsterdam, Netherlands, 4Department of Pediatric Rheumatology and Immunology, Emma Children's Hospital / Academic Medical Center and Reade Institute, Amsterdam, Netherlands, 5Pediatric Rheumatology, St. Lucas Andreas Hospital and Reade Institute, Amsterdam, Netherlands

    Background/Purpose: Evidence that early therapeutic intervention prevents structural damage in juvenile idiopathic arthritis (JIA) patients requires focus on early-stage disease activity scores. Most outcome measures…
  • Abstract Number: 1979 • 2012 ACR/ARHP Annual Meeting

    Care Gap in the Treatment of Patients with High Risk for Fractures in a Single Canadian Academic Center

    Arthur N. Lau1, Michael Branch2, Robert Bensen3, Jonathan D. Adachi4, Alexandra Papaioannou5, William Wong-Pack6 and William G. Bensen7, 1Rheumatology and Clinical Epidemiology, Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 2CEO, Inovex, Oakville, ON, Canada, 3Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, 4St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 5Geriatric Medicine, McMaster University, Hamilton, ON, Canada, 6Department Of Nuclear Medicine, Hamilton, ON, Canada, 7Department of Medicine, Division of Rheumatology, St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada

    Background/Purpose: A number of clinical prediction tools are available to stratify patients into low, moderate and high risk for fractures in future. These tools are…
  • Abstract Number: 1980 • 2012 ACR/ARHP Annual Meeting

    Intermittent Nitrate Use and Risk of Hip Fracture

    Devyani Misra1, Christine Peloquin1, Hyon Choi2, Tuhina Neogi3 and Yuqing Zhang1, 1Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 2Section of Rheumatology and the Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 3Boston University School of Medicine, Boston, MA

    Background/Purpose: Nitrates are commonly used anti-anginal medications which have also been found to promote bone formation and decreases bone resorption.  Intermittent nitrate use has been…
  • Abstract Number: 1981 • 2012 ACR/ARHP Annual Meeting

    Low Body Mass Index, Medication Use and Social Factors Such As Smoking but Not Secondary Medical Disorders or Older Age May Be More Prevalent in Males with Low Bone Mineral Density

    Vandana J. Vedanarayanan, Allison V. Jones and Vikas Majithia, Div of Rheumatology, University of Mississippi Medical Center, Jackson, MS

    Background/Purpose: Osteoporosis (OP) in Males is prevalent and frequently under-recognized. There are a number of known demographic factors such as age, race and BMI as…
  • Abstract Number: 1982 • 2012 ACR/ARHP Annual Meeting

    Five Years of Treatment to Target in Early Active Rheumatoid Arthritis: Prevalence and Predictors of Vertebral Fractures

    L. Dirven1, M. van den Broek2, A.J. Peeters3, N. Riyazi4, P.J.S.M. Kerstens5, T.W.J. Huizinga1, C.F. Allaart1 and W. F. Lems6, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Reinier de Graaf Gasthuis, Delft, Netherlands, 4Rheumatology, Haga Hospital, The Hague, Netherlands, 5Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 6Rheumatology, VU University medical center, Amsterdam, Netherlands

    Background/Purpose: Vertebral fractures (VFs) are more common in patients with rheumatoid arthritis (RA) compared to the general population. It is suggested that an appropriate control…
  • Abstract Number: 1983 • 2012 ACR/ARHP Annual Meeting

    Comparative Risk of Fracture in Men and Women with Human Immunodeficiency Virus

    Lydia Gedmintas1, Elizabeth Wright2, Jeffrey N. Katz3, Elena Losina4 and Daniel H. Solomon5, 1Rheumatology, Brigham's Women's Hospital, Boston, MA, 2Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 3Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA, 4Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 5Division of Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: A growing body of evidence suggests that HIV-positive patients have an increased risk of osteoporosis compared to HIV-negative patients, with some studies suggesting a…
  • Abstract Number: 1985 • 2012 ACR/ARHP Annual Meeting

    The Effect of Calcium and Vitamin D On Bone Loss in an Epileptic Population

    Philip Dussault1, Samuel Davis Jr.2 and Antonio A. Lazzari3, 1Primary Care / Pharmacy, Boston VA HCS, Boston, MA, 2Osteoporosis, Boston VA HCS, Boston, MA, 3Prim Care/Rheumatology, Boston VA Medical Center, Boston, MA

      Background/Purpose: Accelerated rate of bone loss leading to osteopenia and osteoporosis is a well recognized adverse effect of long term anticonvulsant use, particularly phenytoin,…
  • Abstract Number: 1986 • 2012 ACR/ARHP Annual Meeting

    Impaired Endothelial Function in Post-Menopausal Women with Osteoporosis

    Auleen M. Millar1, Aaron McCann2, Vivian McClenaghan2, Paul Hamilton2, Caroline Bleakley2, Kristopher Lyons2 and Gary McVeigh2, 1Rheumatology, Musgrave Park Hospital, Belfast, United Kingdom, 2Department of Therapeutics and Pharmacology, Belfast, United Kingdom

    Background/Purpose: Although traditionally viewed as separate disease entities that increase in prevalence with aging, accumulating evidence indicates that similar pathophysiological mechanisms may underlie cardiovascular disease…
  • Abstract Number: 1987 • 2012 ACR/ARHP Annual Meeting

    A Comparison of Unilateral and Bilateral Hip BMD

    Steven C. Schaub1, Edward S. Leib2 and Diantha Howard3, 1Medical School, U of Vermont College of Med, Burlington, VT, 2Medicine, U of Vermont College of Med, Burlington, VT, 3Statistics, Vermont Center for Clinical and Translational Science, Burlington, VT

    Background/Purpose: The utility of bilateral hip dual energy x-ray absorptiometry scanning for identifying low bone mineral density has been a cause of debate.  Intraperson differences…
  • Abstract Number: 1988 • 2012 ACR/ARHP Annual Meeting

    Zoledronate Efficacy and Safety in Active Paget’s Disease Long-Term Follow-up and Retreatment in Clinical Practice

    Elsa Vieira-Sousa1, Ana M. Rodrigues1, Joana Caetano-Lopes2, Susana Capela3, Filipa Ramos3, Ricardo Figueira3, Joaquim Polido-Pereira1, Cristina Ponte1, Raquel Campanilho-Marques4, Rita Barros3, JC Romeu3 and José A. Pereira da Silva3, 1Rheumatology and Metabolic Bone Diseases Department, Hospital de Santa Maria, CHLN and Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 2Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 3Rheumatology and Metabolic Bone Diseases Department, Santa Maria Hospital,CHLN, Lisbon, Portugal, 4Infection, Inflammation and Rheumatology Section, UCL Institute for Child Health, London, United Kingdom

    Background/Purpose: Bisphosphonates are first line therapy in the treatment of Paget's disease (PD). Zoledronate, a third generation bisphosphonate, has showed high efficacy in the inhibition…
  • Abstract Number: 1989 • 2012 ACR/ARHP Annual Meeting

    Risk Factors for Vertebral Fractures in Patients with Rheumatoid Arthritis – the Tomorrow Study –

    Tadashi Okano1, Tatsuya Koike2, Masahiro Tada1, Kenji Mamoto3, Yuko Sugioka1, Atsuko Kamiyama4 and Hiroaki Nakamura1, 1Orthopedic Surgery, Osaka City University Medical School, Osaka, Japan, 2Center for Senile Degenerative Disorders (CSDD), Osaka City University Medical School, Osaka, Japan, 3Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, 4Rheumatosurgery, Osaka City University Medical School, Osaka, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is one of the causes for secondary osteoporosis. Osteoporosis as a multifactorial disease might be derived from comorbidity itself, poorer physical…
  • Abstract Number: 1990 • 2012 ACR/ARHP Annual Meeting

    Risk of Falling Is Equivalent Between Patients with Rheumatoid Arthritis and Healthy Individuals – the Tomorrow Study-

    Kenji Mamoto1, Tatsuya Koike2, Tadashi Okano1, Atsuko Kamiyama2, Yuko Sugioka1, Masahiro Tada1 and Hiroaki Nakamura1, 1Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Rheumatosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan

    Background/Purpose:  Patients with rheumatoid arthritis (RA) who have muscle weakness and stiff or painful joints might be at increased risk of falling. The present study…
  • Abstract Number: 1991 • 2012 ACR/ARHP Annual Meeting

    Effects of Odanacatib On the Distal Radius and Tibia in Postmenopausal Women: Improvements in Cortical Geometry and Estimated Bone Strength

    Roland Chapurlat1, K. Brixen2, A.M. Cheung3, Sharmila Majumdar4, B. Dardzinski5, A. Cabal5, N. Verbruggen6, S. Ather5, Elizabeth Rosenberg5 and A. de Papp5, 1Hôpital Edouard Herriot, Lyon, France, 2University of Southern Denmark, Odense, Denmark, 3University of Toronto, Ontario, Canada, 4University of California San Francisco, San Francisco, CA, 5Merck Sharp & Dohme Corp., Whitehouse Station, NJ, 6MSD Belgium, Brussels, Belgium

    Background/Purpose: The cathepsin K inhibitor odanacatib (ODN), a novel antiresorptive that preserves bone formation, is currently in phase 3 development for postmenopausal osteoporosis.  In a…
  • Abstract Number: 1992 • 2012 ACR/ARHP Annual Meeting

    Anti-TNF Therapies Improve Bone Mineral Density At the Lumbar Spine of RA Patients by Decreasing Disease Activity and Suppressing Serum RANKL Levels

    Allen P. Anandarajah1, Jennifer Hossler2, Kate Burns3, Kelly Callahan3, Yahui Grace Chiu3 and Jennifer H. Anolik4, 1Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, 2Rheumatology, University of Rochester, Rochester, NY, 3Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 4Medicine- Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY

    Background/Purpose: Generalized bone loss (osteoporosis or osteopenia) is more common in patients with rheumatoid arthritis (RA) than in the general population. Recent studies suggest that…
  • Abstract Number: 1993 • 2012 ACR/ARHP Annual Meeting

    Contribution of Lifestyle Factors to Healthy-Adherer Bias in Prevalent Users of Osteoporotic Drugs

    Mitsuyo Kinjo1 and Daniel H. Solomon2, 1Internal Medicine, Okinawa Chubu Hospital, Uruma City Okinawa, Japan, 2Division of Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Adherence to drug therapy may be a surrogate marker for overall healthy behaviors leading to healthy-adherer bias in epidemiologic studies. This might be particularly…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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