Abstracts Archive - Page 2284 of 2607 - ACR Meeting Abstracts

Abstract Number: 2238 • 2013 ACR/ARHP Annual Meeting
Comparison Of The Long-Term Outcome For Rheumatoid Arthritis Patients With persistent Moderate Disease Activity Or Disease Remission During The First Year After Diagnosis: Data From The Espoir Cohort
Bernard Combe¹, Isabelle Logeart², M. Belkacemi³, S Dadoun⁴, Jean-Pierre Daurès⁵ and Maxime Dougados⁶, ¹Rheumatology, Lapeyronie Hospital, Montpellier I university, Montpellier, France, ²Pfizer, Paris, France, ³CHRU Montpellier, Montpellier, France, ⁴Paris-Pitié Salpêtrière University Hospital, Paris, France, ⁵Service BESPIM, CHU, Nimes, France, ⁶Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France
Background/Purpose: The Treat to Target and EULAR recommendations highlighted the need for achieving and maintaining remission in patients with early RA. We investigated if early…
Abstract Number: 2239 • 2013 ACR/ARHP Annual Meeting
Validation Of a Patient Reported Experience Measure In Patients With Rheumatoid Arthritis
Marwan Bukhari¹, Peter Jones², Ifeanyi Sargeant³, Maureen Cox⁴, Alison Elliott⁵, Suzanne Bullock⁶, Anne O'Brien² and Ailsa Bosworth⁷, ¹Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom, ²Keele University, Keele, United Kingdom, ³IS medical communications, Stafford, United Kingdom, ⁴Nuffield Orthopaedic centre, Oxford, United Kingdom, ⁵Roche Pharmaceuticals, Welwyn Garden City, United Kingdom, ⁶Lancaster University, Lancaster, United Kingdom, ⁷National Rheumatoid Arthritis Society, Maidenhead, United Kingdom
Background/Purpose: Improving patient experience is important in all diseases, but most important in patients with chronic rheumatic diseases like rheumatoid arthritis. To date there…
Abstract Number: 2240 • 2013 ACR/ARHP Annual Meeting
Correlative Analysis Of Swollen Joints Between Clinical Examination and Musculoskeletal Ultrasound For Rheumatoid Arthritis
Kenta Misaki¹, Takashi Nakazawa², Shunichi Fujita¹, Hirotaka Yamada¹ and Toshihiko Yokota¹, ¹Rheumatology, Kurashiki Central Hospital, Kurashiki, Japan, ²Rheumatology, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan
Background/Purpose: The disease activity score 28 (DAS28), clinical disease activity index (CDAI) and simplified disease activity index (SDAI) are all used in the clinical assessment…
Abstract Number: 2241 • 2013 ACR/ARHP Annual Meeting
Assessing Significant Flares In Rheumatoid Arthritis: Validity Of The Outcome Measures In Rheumatology Preliminary Flare Questions In The Canadian Early Arthritis Cohort
Susan J. Bartlett^1,2, Clifton O. Bingham III³, Ernest Choy⁴, Juan Xiong⁵, Gilles Boire⁶, Boulos Haraoui⁷, Janet E. Pope^8,9, J. Carter Thorne¹⁰, Carol A. Hitchon¹¹, Diane Tin¹², Edward C. Keystone¹³ and Vivian P. Bykerk^13,14, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁵Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁶Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁷Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ⁸St Joseph Health Care, London, ON, Canada, ⁹Univ of Western Ontario, London, ON, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ¹⁴Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) flares are common, poorly defined, and understudied. A tool is needed to measure significant RA flares that may signal need for…
Abstract Number: 2242 • 2013 ACR/ARHP Annual Meeting
Patient Versus Physician Joint Counts In Rheumatoid Arthritis Utilizing a Unique Self-Joint Examination Tool
Daisy Bang¹, Yomei Shaw², Christine L. Amity³, Kelly A. Reckley⁴, Ilinca D. Metes⁵ and Marc C. Levesque⁶, ¹Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, ²Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, ³Rheumatology & Clinical Immun, Univ of Pittsburgh, Pittsburgh, PA, ⁴Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁶Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The quantitative assessment of disease activity has been endorsed by the American College of Rheumatology (ACR) to improve rheumatoid arthritis (RA) outcomes. To facilitate…
Abstract Number: 2243 • 2013 ACR/ARHP Annual Meeting
How Well Do The Three Generic Patient Reported Outcomes Measurement Information System Fatigue Instruments Perform In Rheumatoid Arthritis?
Susan J. Bartlett^1,2, Ana-Maria Orbai³, Trisha Duncan³ and Clifton O. Bingham III³, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD
Background/Purpose: NIH Patient-Reported Outcomes Measurement Information System (PROMIS) has created highly precise and efficient instruments to measure patient-reported outcomes across health domains relevant to chronic…
Abstract Number: 2244 • 2013 ACR/ARHP Annual Meeting
Diagnostic Accuracy Of Anti-Ccp Testing For Detecting Prevalent Rheumatoid Arthritis: Results From Screening a Population Based Cohort
Aase Haj Hensvold¹, Patrik KE Magnusson², Lena Israelsson³, Monika Hansson⁴, Vijay Joshua¹, Rikard Holmdahl⁵, Per-Johan Jakobsson³, Johan Askling⁶, Vivianne Malmström⁷, Lars Klareskog³ and Anca I Catrina³, ¹Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ²Medical Epidemiology and Biostatistics, Swedish Twin Registry Karolinska Institutet, Stockholm, Sweden, ³Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, ⁴Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden, ⁶Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁷Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Anti-CCP testing is a part of the clinical routine investigations for rheumatoid arthritis (RA). Previous studies have relative few included controls per patients. We therefor…
Abstract Number: 2245 • 2013 ACR/ARHP Annual Meeting
Predictive Validity Of Low Disease Activity Using Patient Reported Measures On Long-Term Outcomes In Early Rheumatoid Arthritis- Results From Study Of New Onset Rheumatoid Arthritis and Ontario Best Practices Initiative
Pooneh Akhavan¹, Binu Jacob², Paul R. Fortin³, George A. Tomlinson⁴ and Claire Bombardier^5,6, ¹Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ²University Health Network, Toronto General Research Institute, Toronto, ON, Canada, ³University of Laval, Quebec, QC, Canada, ⁴Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada, ⁵Rheumatology, University of Toronto, Toronto, ON, Canada, ⁶Division of rheumatology and Department of Health Policy, Management, and Evaluation, University Health Network, Toronto, ON, Canada
Background/Purpose: Patient reported outcome measures (PROM) are used in routine practice for assessment of disease activity. They have been shown to correlate well with other…
Abstract Number: 2246 • 2013 ACR/ARHP Annual Meeting
Patients’ Assessment of the Disease Greatly Influences the Determination of Disease Activity and Remission in Rheumatoid Arthritis
Kenrin Shi^1,2, Kenji Miki^1,3, Masao Yukioka¹, Kosuke Ebina², Shoichi Kaneshiro² and Hideki Yoshikawa², ¹Department of Orthopaedic Surgery, Yukioka Hospital, Osaka, Japan, ²Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan, ³Department of Orthopaedic Surgery, Amagasaki Central Hospital, Amagasaki, Japan
Background/Purpose: Recently defined remission criteria of rheumatoid arthritis (RA), Boolean criteria or Simplified Disease Activity Index (SDAI)
Abstract Number: 2247 • 2013 ACR/ARHP Annual Meeting
Response To a Sleep Query On The Multi-Dimensional Health Assessment Questionnaire (MDHAQ) Is Related To Levels Of Disease Activity
Martin J. Bergman^1,2, Sapna Sangani³, Isabel Castrejón⁴ and Theodore Pincus⁴, ¹Medicine, Drexel University College of Medicine, Philadelphia, PA, ²Taylor Hospital, Ridley Park, PA, ³Medicine, Mercy Catholic Medical Center, Lansdowne, PA, ⁴Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Patients with rheumatoid arthritis (RA) often report fatigue, but a possible impact of disease on sleep and/or on disease activity are poorly characterized. We…
Abstract Number: 2248 • 2013 ACR/ARHP Annual Meeting
Difference Between The Two Versions Of Disease Activity Score Based On C-Reactive Protein and Erythrocyte Sedimentation Rate
Pinar Cetin¹, Dilek Solmaz¹, Hacer Gulluoglu², Ismail Sari¹, Merih Birlik¹, Servet Akar¹, Fatos Onen¹ and Nurullah Akkoc¹, ¹Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey, ²Internal Medicine, Dokuz Eylul University School of Medicine, Ýzmir, Turkey
Background/Purpose: In some countries reimbursement criteria require a DAS28 score of >5.1 for initiating anti-TNF therapy in patients with rheumatoid arthritis. DAS28 score can be…
Abstract Number: 2249 • 2013 ACR/ARHP Annual Meeting
What Proportion Of Patients With Rheumatoid Arthritis Fail To Achieve Remission Based On The Patient Global? An Analysis From The Prospective, Observational Biologic Treatment Registry Across Canada
Andrew Chow¹, Philip Baer², William G. Bensen³, Isabelle Fortin⁴, Majed M. Khraishi⁵, Dalton E. Sholter⁶, May Shawi⁷, Allen J. Lehman⁸, Susan M. Otawa⁸, Emmanouil Rampakakis^9,10 and John S. Sampalis^9,10, ¹University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, ²Private Practice, Scarborough, ON, Canada, ³Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁴Centre de rhumatologie de l'est du Québec (CREQ), Rimouski, QC, Canada, ⁵Nexus Clinical Research, St John's, NF, Canada, ⁶Rheumatology Associates, Edmonton, AB, Canada, ⁷Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada, ⁸Medical Affairs, Janssen Inc., Toronto, ON, Canada, ⁹JSS Medical Research, Montreal, QC, Canada, ¹⁰Jewish General Hospital, McGill University, Montreal, QC, Canada
Background/Purpose: According to the latest ACR/EULAR guidelines, Boolean remission in RA is defined as achievement of patient global assessment (PtGA) ≤1, 28-swollen joint count (SJC)…
Abstract Number: 2222 • 2013 ACR/ARHP Annual Meeting
Positive Allosteric Modulation Of The Adenosine A_2a Receptor Alters Inflammatory Cytokine Production and Alleviates Chronic Arthritis In Rats
Ajith A. Welihinda, Jordan A. Mechanic and Edward P. Amento, Molecular Medicine Research Institute, Sunnyvale, CA
Background/Purpose: Rheumatoid arthritis is a chronic systemic autoimmune disease characterized by inflammation and joint destruction; a consequence of which is the high local concentration of…
Abstract Number: 2225 • 2013 ACR/ARHP Annual Meeting
COVA322: A Novel, Bispecific Tumor-Necrosis-Factor-Alpha / Interleukin-17A (TNF/IL-17A) Inhibitor With Excellent Pharmacokinetic Properties In Mice and Cynomolgus Monkeys
Mathias Locher, Dragan Grabulovski, Isabella Attinger-Toller, Susann Koenig-Friedrich, Ulrike von der Bey and Julian Bertschinger, Covagen AG, Schlieren, Switzerland
Background/Purpose: The generation of bispecific antibody molecules with excellent biophysical and pharmacokinetic properties has been a challenging task in the past. We present here COVA322,…
Abstract Number: 2210 • 2013 ACR/ARHP Annual Meeting
Involvement In Leisure Activities Among Children and Youth With Juvenile Idiopathic Arthritis
Sabrina Cavallo¹, Annette Majnemer², Ciaran M. Duffy³ and Debbie Ehrmann Feldman⁴, ¹Public Health-Epidemiology, Université de Montréal, Montreal, QC, Canada, ²School of Physical and Occupational therapy, McGill university, Montreal, QC, Canada, ³Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁴Rehabilitation, Université de Montréal, Montreal, QC, Canada
Background/Purpose: Children with arthritis may be at greater risk for adopting a more sedentary lifestyle compared to their healthy peers in part due to disease…

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