ACR Meeting Abstracts

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  • Abstract Number: 2211 • 2012 ACR/ARHP Annual Meeting

    Is It Useful to Repeat an MRI of the Sacroiliac Joints in the Diagnostic Work-up for Spondyloarthritis?

    Rosaline van den Berg1, Manouk de Hooge1, Victoria Navarro-Compán1, Floris van Gaalen1, Monique Reijnierse2, Tom Huizinga1 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: In the diagnostic work-up of spondyloarthritis (SpA), imaging of the sacroiliac joints by MRI (MRI-SIJ) is an important step. One study showed that in…
  • Abstract Number: 2212 • 2012 ACR/ARHP Annual Meeting

    How Much Does the Spondyloarthritis Research Consortium of Canada Score of the Sacroiliac Joints Change Over a 3-Month Period in Patients On Non-Biological Treatment?

    Rosaline van den Berg1, Manouk de Hooge1, Victoria Navarro-Compán1, Floris van Gaalen1, Monique Reijnierse2, Tom Huizinga1 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The SpondyloArthritis Research Consortium of Canada (SPARCC) score of the sacroiliac joints (SIJ) is often used in clinical trials to detect changes over time.…
  • Abstract Number: 2213 • 2012 ACR/ARHP Annual Meeting

    Ankylosing Spondylitis Is Strongly Related to Clinical Spine Fractures Independently of Drugs Use: A Register-Based Case-Control Study

    Daniel Prieto-Alhambra1, Juan Muñoz-Ortego2, Cyrus Cooper3, Adolfo Díez-Pérez4 and Peter Vestergaard5, 1Internal Medicine; Primary Care; NDORMS Dept; MRC Lifecourse Epidemiology Unit, URFOA-IMIM, Parc de Salut Mar; Idiap Jordi Gol; University of Oxford; University of Southampton, Barcelona, Spain, 2Rheumatology, Hospital Sagrat Cor, Barcelona (Spain), Spain, 3NDORMS; MRC Lifecourse Epidemiology Unit, University of Oxford; Southampton General Hospital, Southampton, United Kingdom, 4Internal Medicine, Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Barcelona; and RETICEF, ISCIII Madrid; Spain, Barcelona, Spain, 5Endocrinology and Internal Medicine (MEA), Aarhus University Hospital THG, Aarhus (Denmark), Aarhus, Denmark

    TITLE: "Ankylosing Spondylitis is strongly related to clinical spine fractures independently of drugs use: a register-based case-control study."Background/Purpose: Ankylosing Spondylitis (AS) is associated not only…
  • Abstract Number: 2214 • 2012 ACR/ARHP Annual Meeting

    Similar Levels of Disease Activity in Patients with Oligoarticular Vs. Polyarticular Peripheral Spondyloarthritis

    Filip Van den Bosch1, Philip J. Mease2, Désirée van der Heijde3, Martin Rudwaleit4, Katie Obermeyer5 and Aileen L. Pangan5, 1Ghent University Hospital, Ghent, Belgium, 2Rheumatology Research, Swedish Medical Center, Seattle, WA, 3Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Endokrinologikum Berlin, Berlin, Germany, 5Abbott Laboratories, Abbott Park, IL

    Background/Purpose: The ASAS criteria for peripheral spondyloarthritis (SpA) allow for classification of patients with SpA who present with peripheral arthritis, enthesitis and/or dactylitis.1 ABILITY-2, a…
  • Abstract Number: 2215 • 2012 ACR/ARHP Annual Meeting

    Assessment of Vascular Age in Psoriatic Arthritis Patients

    Jl Rosales-Alexander1, César Magro Checa1, Juan Salvatierra1, Jesús Cantero Hinojosa2 and Enrique Raya Álvarez1, 1Rheumatology, University Hospital San Cecilio, Granada, Spain, 2Internal Medicine, University Hospital San Cecilio, Granada, Spain

    Background/Purpose: The European League Against Rheumatism (EULAR) recommends cardiovascular risk (CV) assessment using the systematic coronary risk evaluation (SCORE) chart in inflammatory arthritis patients. However,…
  • Abstract Number: 2216 • 2012 ACR/ARHP Annual Meeting

    Cardiovascular Risk Assessment in Spondyloarthritis Using the Score Chart and Reclassification by Presence of Plaques On Ultrasonography

    Jl Rosales-Alexander1, Juan Salvatierra1, César Magro Checa1, Jesús Cantero Hinojosa2 and Enrique Raya Álvarez1, 1Rheumatology, University Hospital San Cecilio, Granada, Spain, 2Internal Medicine, University Hospital San Cecilio, Granada, Spain

    Background/Purpose: Increased cardiovascular (CV) risk have been described in patients with rheumatic diseases including spondyloarthritis (SpA). Besides traditional CV risk factors, disease specific factors have…
  • Abstract Number: 2217 • 2012 ACR/ARHP Annual Meeting

    Even After Pretreatment with up to Three Biologics, Anti-TNFs Shows Effectiveness in Active Psoriatic Arthritis Patients

    Frank Behrens1, Michaela Koehm1, Diamant Thaci2, Brigitte Krummel-Lorenz3, Gerd Greger4, Bianca Wittig4 and Harald Burkhardt5, 1CIRI/Div. Rheumatology, J.W. Goethe-University, Frankfurt/Main, Germany, 2Klinik für Dermatologie, Venerologie und Allergologie, J.W. Goethe University, Frankfurt/Main, Germany, 3CIRI/Endokrinologikum, Frankfurt/Main, Germany, 4Abbott GmbH & Co KG, Wiesbaden, Germany, 5CIRI /Div. of Rheumatology, Goethe-University, Frankfurt/Main, Frankfurt/Main, Germany

    Background/Purpose: For the treatment of patients with psoriatic arthritis (PsA) only antiTNF biologics are licensed. Therefore, failures to anti-TNF are often switched to a different…
  • Abstract Number: 2218 • 2012 ACR/ARHP Annual Meeting

    5 Year Safety, Efficacy, and Radiographic Data in Patients with Active Psoriatic Arthritis Treated with Golimumab: Results From the Long-Term Extension of a Randomized, Placebo-Controlled Study

    Arthur Kavanaugh1, Desiree M. van der Heijde2, Iain B. McInnes3, Philip J. Mease4, Gerald G. Krueger5, Dafna D. Gladman6, Yiying Zhou7, J. D. Lu8, Zhenhua Xu9, Lenore Noonan10 and Anna Beutler9, 1UCSD School of Medicine, La Jolla, CA, 2Dept of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3University of Glasgow, Glasgow, United Kingdom, 4Rheumatology Research, Swedish Medical Center, Seattle, WA, 5School of Medicine, University of Utah, Salt Lake City, UT, 6Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 7Biostatistics, Janssen Research & Development, LLC., Spring House, PA, 8Janssen Research & Development, LLC, Spring House, PA, 9Janssen Research & Development, LLC., Spring House, PA, 10Immunology, Janssen Research & Development, LLC., Spring House, PA

    5 year safety, efficacy, and radiographic data in patients with active psoriatic arthritis treated with golimumab: Results from the long-term extension of the randomized, placebo-controlled,…
  • Abstract Number: 2219 • 2012 ACR/ARHP Annual Meeting

    Patients with Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis Show Similar Response Rates After One Year of Treatment with Etanercept –  results of the Esther Trial

    In-Ho Song1, Kay-Geert A. Hermann2, Hildrun Haibel1, Christian Althoff3, Denis Poddubnyy4, Joachim Listing5, Anja Weiß6, Ekkehard Lange7, Bruce Freundlich8, Martin Rudwaleit9 and Joachim Sieper10, 1Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, 2Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, 3Radiology, Charite Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, 4Charité Universitätsmedizin Berlin, Berlin, Germany, 5German Rheumatism Research Center, Berlin, Germany, 6German Rheumatism Research Centre, Berlin, Germany, 7BU Specialty Care, Pfizer Pharma AG, Berlin, Germany, 8University of Pennsylvania, Philadelphia, PA, 9Endokrinologikum Berlin, Berlin, Germany, 10Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany

    Background/Purpose: In patients with early axial spondyloarthritis (SpA) with a disease duration < 5 years we assessed whether there is a difference to etanercept (ETA)…
  • Abstract Number: 2220 • 2012 ACR/ARHP Annual Meeting

    Development of the Pulsar (Program to Understand the Longterm Outcomes in Spondyloarthritis) Registry

    Andreas M. Reimold1, Liron Caplan2, Daniel O. Clegg3, Gail S. Kerr4, Elizabeth Chang5, Lisa A. Davis6, Prashant Kaushik7, Vikas Majithia8, J. Steuart Richards9, Joel D. Taurog10 and Jessica Walsh11, 1Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, 2Div of Rheumatology, Denver VA and Univ of Colorado School of Medicine, Aurora, CO, 3Division of Rheumatology, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, 4Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, 5Phoenix VAHCS, Phoenix, AZ, 6Division of Rheumatology, Denver Health and Hospital Authority, Denver, CO, 7Department of Medicine, Sratton VAMC, Albany, NY, 8Div of Rheumatology, University of Mississippi Medical Center, Jackson, MS, 9Rheumatology, Washington DC VA and Georgetown University, Washington, DC, 10Internal Medicine, Rheumatic Diseases Division, UT Southwestern Medical Center, Dallas, TX, 11Rheumatology, University of Utah Hospital, Salt Lake City, UT

    Background/Purpose: The spondyloarthritides are a group of conditions characterized by inflammation in the axial skeleton or peripheral joints.  The arthritis may present as the primary…
  • Abstract Number: 2221 • 2012 ACR/ARHP Annual Meeting

    Major Adverse Cardiovascular Events Are More Common in Rheumatoid Arthritis Than in Psoriatic Arthritis and Are Associated with Different Risk Factors

    Allen P. Anandarajah1, Katherine C. Saunders2, George W. Reed3, Alina U. Onofrei3, Jeffrey D. Greenberg4 and Christopher T. Ritchlin5, 1Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, 2Corrona, LLC., Southborough, MA, 3University of Massachusetts Medical School, Worcester, MA, 4NYU Hospital for Joint Diseases, New York, NY, 5Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY

    Background/Purpose: Rheumatoid Arthritis (RA) is associated with increased cardiovascular mortality and morbidity rates. Similarly several studies have reported an increased risk for cardiovascular events in…
  • Abstract Number: 2182 • 2012 ACR/ARHP Annual Meeting

    Prevalence of Fibromyalgia Is Increased in Primary Sjögren’s Syndrome Compared with SLE and Associated with Depression and Severe Vitamin D Deficiency

    Byoong Yong Choi1, Hye Jin Oh2, Jun Won Park3, Bon Seung Ku2, Sung Hae Chang2, Eun Young Lee2, Eun Bong Lee2 and Yeong Wook Song4, 1Division of Rheumatology, Department of Internal Medicine, Seoul Medical Center, Seoul, South Korea, Seoul, South Korea, 2Internal Medicine, Seoul National University Hospital, Seoul, South Korea, 3Division of Rheumatology, Department of Internal Medicine, Rheumatology, Seoul National University, Seoul, South Korea, 4Internal Medicine,, Seoul National University Hospital, Seoul, South Korea

    Background/Purpose: Although clinical features of primary Sjögren's syndrome (pSS) overlap with those of fibromyalgia (FM), the relationship between FM and pSS has remained unclear. Furthermore,…
  • Abstract Number: 2183 • 2012 ACR/ARHP Annual Meeting

    Common Features in Lymphoproliferative Complications in the Course of Primary Sjögren’s Syndrome: Results From a Multicenter Cohort of 1170 Patients

    Luca Quartuccio1, Chiara Baldini2, Roberta Priori3, Elena Bartoloni Bocci4, Francesco Carubbi5, Miriam Isola6, Marta Maset7, Sara Salvin7, Nicoletta Luciano2, Giovanna Picarelli8, Alessia Alunno9, Roberto Giacomelli10, Roberto Gerli11, Guido Valesini12, Stefano Bombardieri13 and Salvatore De Vita1, 1Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy, 2University of Pisa, Rheumatology Unit, Pisa, Italy, 3Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, 4Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Perugia, Italy, 5Rheumatology Clinic, University of L'Aquila, L'Aquila, Italy, 6Institute of Statistics, University of Udine, Udine, Italy, 7Rheumatology Clinic, DSMB, University of Udine, Italy, Udine, Italy, 8Rheumatology Unit, Sapienza University of Rome, Rome, Italy, 9Clinical and Experimental Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy, 10Rheumatology Unit, University of Aquila, L'Aquila, Italy, 11Rheumatology Unit, University of Perugia, Perugia, Italy, 12Clinica e Terapia Medica, Sapienza, Universita di Roma, Rome, Italy, 13Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy

    Background/Purpose: To describe the prevalence of lymphoproliferative complications (defined as B-cell lymphoma or definite conditions predisposing to lymphoma, i.e,  cryoglobulinemic vasculitis (CV) and major salivary…
  • Abstract Number: 2184 • 2012 ACR/ARHP Annual Meeting

    Pregnancy and Fetal Outcome in Patients with an Established Diagnosis of Primary Sjögren’s Syndrome.

    Roberta Priori1, Angelica Gattamelata2, Mariagrazia Modesti3, Serena Colafrancesco3, Marta Maset4, Luca Quartuccio4, Salvatore De Vita5, Elena Bartoloni Bocci6, Alessia Alunno7, Roberto Gerli6, Francesca Strigini8, Chiara Baldini9, Chiari Tani9, Marta Mosca9, Stefano Bombardieri9 and Guido Valesini3, 1Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, 2Sapienza University of Rome, Rome, Italy, 3Rheumatology Unit, Sapienza University of Rome, Rome, Italy, 4Rheumatology Clinic, DSMB, University of Udine, Udine, Italy, 5Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy, 6Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Perugia, Italy, 7Clinical and Experimental Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy, 8Internal Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, 9Rheumatology Unit, University of Pisa, Pisa, Italy

    Background/Purpose: To investigate pregnancy and fetal outcome in patients with an established diagnosis of primary Sjögren’s syndrome (pSS) Methods: The clinical charts of 1075 women with…
  • Abstract Number: 2185 • 2012 ACR/ARHP Annual Meeting

    Prevalence of Severe Extra-Glandular Manifestations in a Large Cohort of Patients with Primary Sjögren’s Syndrome

    Chiara Baldini1, Pasquale Pepe2, Luca Quartuccio3, Roberta Priori4, Elena Bartoloni Bocci5, Alessia Alunno6, Serena Colafrancesco7, Angelica Gattamelata8, Marta Maset9, Mariagrazia Modesti7, Antonio Tavoni10, Salvatore De Vita9, Roberto Gerli5, Guido Valesini7 and Stefano Bombardieri11, 1University of Pisa, Rheumatology Unit, Pisa, Italy, 2Department of Internal Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, 3Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy, 4Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, 5Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Perugia, Italy, 6Clinical and Experimental Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy, 7Rheumatology Unit, Sapienza University of Rome, Rome, Italy, 8Sapienza University of Rome, Rome, Italy, 9Rheumatology Clinic, DSMB, University of Udine, Italy, Udine, Italy, 10University of Pisa, Immunoallergology Unit, Pisa, Italy, 11Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy

    Background/Purpose: i) to describe the clinico- serological features of a cohort of 1115 patients with primary Sjögren’s syndrome (pSS); ii) to assess the prevalence of systemic extra-glandular…
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