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  • Abstract Number: 2452 • ACR Convergence 2024

    Multimodal Ultrasound in the Assessment of Sarcopenia-related Muscle Involvement in Patients with Systemic Sclerosis: A Multicentric Study

    Riccardo Bixio1, Maria Giovanna Lommano2, Seda Colak3, Sonia farah4, Francesca Pistillo5, Richard Wakefield6, Fausto Salaffi4, Stefano Di Donato7, Ombretta Viapiana5, Rossella De Angelis8, Maurizio Rossini5, Edoardo Cipolletta9, Emilio Filippucci10, Luca Idolazzi5, Francesco Del Galdo11 and Andrea Di Matteo12, 1University of Verona, Verona, Verona, Italy, 2Università Politecnica delle Marche, Jesi, Italy, 3Gulhane Training and Research Hospital, Ankara, Turkey, 4Polytechnic University of Marche, Jesi (AN), Italy, 5Rheumatology Unit, University of Verona, Verona, Italy, 6NIHR Leeds Biomedical Research Centre, Leeds, UK., Leeds, United Kingdom, 7Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 8Polytechnic University of Marche, Ancona, Italy, Ancona, Italy, 9Polytechnic University of Marche, Ancona, Italy, 10Rheumatology Unit, Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Jesi, Ancona, Italy, Jesi, Italy, 11University of Leeds, Leeds, United Kingdom, 12Faculty of Medicine and Health, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom

    Background/Purpose: Patients with systemic sclerosis (SSc) are at an increased risk of sarcopenia and muscle involvement. This study aims to describe the ultrasound findings of…
  • Abstract Number: 2680 • ACR Convergence 2024

    Thrombocytopenia in Patients with Systemic Lupus ErythematosusReal-World Data Based on a Nationwide Database, RISE

    Omer Pamuk1, Jessica Fitzpatrick2, Jing Li3, Gabriela Schmajuk4 and Marina Magrey5, 1University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 2University California, San Francisco, San Francisco, CA, 3University of California, San Francisco, San Francisco, CA, 4UCSF / SFVA, San Francisco, CA, 5Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with a very heterogeneous presentation. Thrombocytopenia (TP) is an infrequent presentation in patients with SLE…
  • Abstract Number: 2566 • ACR Convergence 2024

    Detrimental Effects of Proton Pump Inhibitors on Bone Mineral Density Are Not Mediated by Changes in Serum Calcium or Parathyroid Hormone in Patients with Inflammatory Rheumatic Diseases: A Cross-sectional Study

    andriko Palmowski1, Zhivana Boydzhieva2, Paula Hoff3, Sandra Hermann3, burkhard Muche3, David Simon4, Gerhard Krönke3, Edgar Wiebe5 and FRANK HARTMUT DR. BUTTGEREIT5, 1Charité - Universittsmedizin Berlin, Berlin, Germany, 2Charité Universittsmedizin, Berlin, Germany, 3Rheumatology, Charité, Berlin, Germany, 4Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany/ Department of Internal Medicine 3, University of Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany/Deutsches Zentrum für Immuntherapie (DZI), University of Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Berlin, Germany, 5Charité University Medicine Berlin, Berlin, Germany

    Background/Purpose: In a previous study, we found daily proton pump inhibitor (PPI) intake to be associated with decreased bone mineral density in patients with inflammatory…
  • Abstract Number: 0598 • ACR Convergence 2024

    Cardio-metabolic Effects of Apremilast in Patients with Psoriatic Arthritis: A Prospective Cohort Study

    Eva van Geel1, Romy Hansildaar2, Fatih Çoban1, Bas Dijkshoorn1, Maaike Heslinga1, Reinhard Bos3, Mies Korteweg1, Arno Van Kuijk1 and Michael Nurmohamed4, 1Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center location Reade, Amsterdam, Netherlands, 3Medical Center Leeuwarden, Leeuwarden, Netherlands, 4Reade and Amsterdam UMC, Kortenhoef, Netherlands

    Background/Purpose: Psoriatic arthritis (PsA) is associated with metabolic and cardiovascular disease. Studies have suggested that treatment with apremilast is associated with weight loss and other…
  • Abstract Number: 2661 • ACR Convergence 2024

    Changes in Krebs Von Den Lungen 6 Levels (∆KL6) Predict Fibrosing Progression of Interstitial Lung Disease in Patients with an Underlying Connective Tissue Disease (CTD-ILD)

    Fredeswinda Romero-Bueno1, María Carmen Vegas-Sánchez2, lydia Abasolo Alcazar3, Mª Jesus Rodriguez Nieto2, Cristina Vadillo-Font4, M Asuncion Nieto5, Laura Cebrián6, Belén López-Muñiz6, Jesus Loarce Martos7, Juan Rigual8, hildegarda Godoy Tundidor9, Rosalía Laporta10, Irene Llorente-Cubas11, Gema Bonilla12, Luis Gomez Carrera13, Rosario García-Vicuña14, Ana Jaureguizar7, Jose Luis Morell Hita7, Claudia Valenzuela15 and Olga Sánchez-Pernaute16, and the NEREA Study group for Autoimmune ILD, 1Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 2Hospital Universitario Fundación Jiménez Díaz and IIS-FJD, Madrid, Spain, 3IdISSC. HCSC, Madrid, Spain, 4Hospital Clinico S Carlos, Madrid, Spain, 5Hospital Clínico San Carlos, Madrid, Madrid, Spain, 6Hospital Universitario Infanta Leonor, Madrid, Spain, 7Hospital Universitario Ramón y Cajal - IRYCIS, Madrid, Spain, 8Ramón y Cajal University Hospital, Madrid, Madrid, Spain, 9Servicio de Reumatología, Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA , Madrid, Madrid, Spain, 10Hospital Universitario Puerta de Hierro, Madrid, Spain, 11Hospital Universitario de La Princesa, Madrid, Spain, 12H. Universitario La Paz, Madrid, Spain, 13Hospital Universitario La Paz, Madrid, Spain, 14Hospital Universitario de la Princesa, Madrid, Madrid, Spain, 15Hospital Universitario La Princesa, Madrid, Spain, 16Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain

    Background/Purpose: Krebs von den Lungen-6 (KL6) is a mucin-1 glycoprotein produced by type 2 alveolar epithelial cells , which increase at peripheral blood show a…
  • Abstract Number: 2581 • ACR Convergence 2024

    Vunakizumab in Patients with Active Psoriatic Arthritis: A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 2 Study

    Hejian Zou1, Weiguo Wan2, Yu Xue1, Lingyun Sun3, Ning Zhang4, Haiying Chen5, Xiaofei Shi6, Shengyun Liu7, Lin Chen8, Xinmei Ma9, Hua Wei10, Zhenyu Jiang11, Xiaomei Li12, Hongtao Fan13, Hongbin Li14, Jingyang Li15, Rui Wu16, Guixiu Shi17, Jing Zhu18, Xiaodan Kong19, Yuewu Lu20, Xiaojing Cui21, Qianning Zheng21, Xiaoyan Bai22 and Guangchao Dong21, 1Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China, Shanghai, China (People's Republic), 2Huashan Hospital, Fudan University, Shanghai, China (People's Republic), 3Dept of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing Univ Medical School, Nanjing, CN, Nanjing, China (People's Republic), 4Shengjing Hospital Affiliated to China Medical University, Shenyang, China (People's Republic), 5The Third Hospital of Hebei Medical University, Shijiazhuang, China (People's Republic), 6The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China (People's Republic), 7The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (People's Republic), 8Jilin Province People's Hospital, Changchun, China (People's Republic), 9Zaozhuang Municipal Hospital, Zaozhuang, China (People's Republic), 10Subei People's Hospital of Jiangsu Province, Yangzhou, China (People's Republic), 11The First Hospital of Jilin University, Changchun, China (People's Republic), 12The First Affiliated Hospital of the University of Science and Technology of China, Hefei, China (People's Republic), 13The First People's Hospital of Yunnan Province, Kunming, China (People's Republic), 14Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China (People's Republic), 15Zhuzhou Central Hospital, Zhuzhou, China (People's Republic), 16The Tirst Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China (People's Republic), 17The First Affilated Hospital of Xiamen University, Xiamen, China (People's Republic), 18Sichuan Provincial People's Hospital, Chengdu, China (People's Republic), 19The Second Affiliated Hospital of Dalian Medical University, Dalian, China (People's Republic), 20BeiJing Chao-Yang Hospital, Capital Medical University, Beijing, China, 21Jiangsu Hengrui Pharmaceuticals Co., Ltd., Shanghai, China (People's Republic), 22Jiangsu Hengrui Pharmaceuticals Co., Ltd., Beijing, China

    Background/Purpose: Patients with psoriasis often develop psoriatic arthritis (PsA), a chronic systemic inflammatory disease with a severe clinical burden that impairs quality of life. In…
  • Abstract Number: 0623 • ACR Convergence 2024

    Select Patient Reported Outcome Measure Domains Enhance Immune Mediator Based Indexes That Inform Flare Risk and Disease Activity in Systemic Lupus Erythematosus

    Melissa Munroe1, Daniele DeFreese2, Adrian Holloway2, Mohan Purushothaman2, Wade DeJager3, Susan Macwana3, Joel Guthridge4, Stan Kamp3, Nancy Redinger3, Teresa Aberle4, Eliza Chakravarty4, Cristina Arriens4, Yanfeng Li5, hu Zeng5, Uma Thanarajasingam5, Judith James4 and Eldon Jupe2, 1Oklahoma Medical Research Foundation; Progentec Diagnostics, Inc., Oklahoma City, OK, 2Progentec Diagnostics, Inc., Oklahoma City, 3Oklahoma Medical Research Foundation, Oklahoma City, 4Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Mayo Clinic, Rochester

    Background/Purpose: We have recently validated a plasma Lupus Flare Risk Index (L-FRI; Munroe et al. Ann Rheum Dis. 2024. 83 [Supp 1]: 402) and Lupus…
  • Abstract Number: 0390 • ACR Convergence 2024

    Treatment Effectiveness Following Switching from Initial TNF Inhibitor in Juvenile Idiopathic Arthritis

    Mei-Sing Ong1, Sarah Ringold2, Melissa Mannion3, Marc Natter4 and Yukiko Kimura5, 1Harvard Medical School & Harvard Pilgrim Healthcare Institute, Boston, MA, 2Washington University, Seattle, 3University of Alabama at Birmingham, Birmingham, AL, 4Boston Children's Hospital, Boston, MA, 5Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: Although the increasing availability of biologic therapies has significantly improved outcomes for patients with JIA, a substantial proportion of patients require switching from the…
  • Abstract Number: 0368 • ACR Convergence 2024

    Development and Validation of a Patient-centered Self-evaluation Questionnaire in Systemic Lupus Erythematosus: LUPIN®

    Marc Scherlinger1, Jean-Francois Kleinmann1, Antonin Folliasson2, Marianne Riviere3, Raphaelle Rybak4, Sabine Malivoir5, Jean-François Viallard6, Estibaliz Lazaro7, Christophe Richez8, Irene Machelart9, Nadine Magy-Bertrand10, Audrey Gorse11, Gilles Blaison12, Julien Campagne13, Benjamin Dervieux14, Thomas Moulinet15, Roland Jaussaud16, Pascal Roblot17, Mathieu Puyade17, Amélie Servettaz18, Pauline Orquevaux18, Julie le Scanff19, DANIEL WENDLING20, Marc Andre21, Ludovic Trefond21, Perrine SMETS22, Nicolas Baillet23, Christophe Deligny24, Xavier Mariette25, ARNAUD HOT26, Emmanuelle David27, Laurent Perard28, Estelle Jean29, Sarah Permal30, Denis WAHL31, Christian Agard32, François Chasset33, Baptiste Hervier34, Pasquer Ronan2, Mickael Martin17, Ludivine Lebourg35, Frederic Renou36, Loic Raffray36, Elisabeth Diot37, Cecile Fermont38, Thierry Martin39, Anne-Sophie Korganow39, Jacques-Eric Gottenberg40, Jean Sibilia41 and Zahir Amoura42, 1Strasbourg University Hospital - National reference center for autoimmune disease, Rheumatology, Strasbourg, France, 2Hometrix Health, Paris, France, 3Association Francaise du Lupus et autres maladies autoimmunes (AFL+), Metz, France, 4Association Francaise du Lupus et autres maladies autoimmunes (AFL+), Paris, France, 5APHP Pitié Salpêtrière - National reference center for autoimmune disease, Internal Medicine, Paris, France, 6CHU de Bordeaux, Hôpital Haut-Lévêque, Pessac, FR, Bordeaux, France, 7Bordeaux University Hospital, Pessac, France, 8Université de Bordeaux, Bordeaux, France, 9CH de Bayonne - Competence center for autoimmune diseases, Internal Medicine, Bayonne, France, 10CHU de Besancon - Competence center for autoimmune diseases, Internal Medicine, Besançon, France, 11CH de Chambery - Competence center for autoimmune diseases, Internal Medicine, Chambery, France, 12CH de Colmar - Competence center for autoimmune diseases, Internal Medicine, Colmar, France, 13Hôpital Robert Schuman - Competence center for autoimmune diseases, Internal Medicine, Metz, France, 14CH de Mulhouse - Competence center for autoimmune diseases, Internal Medicine, Mulhouse, France, 15CHRU de Nancy, Vandœuvre-lès-Nancy, France, 16CHU de Nancy - Competence center for autoimmune diseases, Internal Medicine, Nancy, France, 17CHU de Poitiers - Competence center for autoimmune diseases, Internal Medicine, Poitiers, France, 18CHU de Reims - Competence center for autoimmune diseases, Internal Medicine, Reims, France, 19CH - Competence center for autoimmune diseases, Internal Medicine, Villefranche-sur-Saone, France, 20University Hospital, Besançon, France, 21CHU de Clermont-Ferrand - National reference center for autoimmune disease, Internal Medicine, Clermont-Ferrand, France, 22Clermont Ferrand University Hospital - National reference center for autoimmune disease, Internal Medicine, Clermont-Ferrand, France, 23CH de Basse-Terre - Competence center for autoimmune diseases, Internal Medicine, Basse-Terre, France, 24University Hospital of Martinique - National reference center for autoimmune disease, Internal Medicine, Fort-de-France, Martinique, 25Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin Bicetre, France, 26Service de Médecine interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France, 27HCL - Croix Rousse, Internal Medicine, Lyon, France, 28Hopital Saint-Joseph, Internal Medicine, Lyon, France, 29APHM - La Timone, Internal Medicine, Marseille, France, 30CH Mayotte - CH Wallis-et-Futuna, Internal Medicine, Mamoudzou, Mayotte, 31Lorraine University, Nancy, France, 32CHU de Nantes - National reference center for autoimmune disease, Internal Medicine, Nantes, France, 33Dermatology, Hôpital Tenon, Paris, France, 34APHP Saint-Louis - National reference center for autoimmune disease, Internal Medicine, Paris, France, 35CHU de Rouen, Internal Medicine, Rouen, France, 36CHU La Réunion - Competence center for autoimmune diseases, Internal Medicine, Saint-Denis, Reunion, 37CHU de Tours - Competence center for autoimmune diseases, Internal Medicine, Tours, France, 38CH de Valence - Competence center for autoimmune diseases, Internal Medicine, Valence, France, 39Strasbourg University Hospital, National reference center for autoimmune disease, Clinical Immunology, Strasbourg, France, 40Rheumatology Department, Strasbourg University Hospital,, Strasbourg, France, 41Strasbourg University Hospital, National reference center for autoimmune disease, Rheumatology, Strasbourg, France, 42French National Reference Centre for Systemic Lupus Erythematosus, Pitié-Salpêtrière Hospital, Paris, France

    Background/Purpose: Systemic Lupus Erythematosus (SLE) features unpredictable disease activity fluctuations, making flare hard to detect and significantly impairing quality of life. This highlights the need…
  • Abstract Number: 0365 • ACR Convergence 2024

    Patients’ Behaviors and Beliefs Around Dietary Changes Among a Cohort of Patients with Rheumatic Disease

    Aaron Stubbs, Deeba Minhas, Anne Arewasikporn and Andrew Schrepf, University of Michigan, Ann Arbor, MI

    Background/Purpose: Dietary interventions may help manage inflammation and are considered for adjunctive treatment of rheumatic diseases.  Our study aimed to explore patients' behaviors and beliefs…
  • Abstract Number: 0374 • ACR Convergence 2024

    How Do Patient Decision Aids Enable Purposeful Shared Decision-Making in Rheumatology? An Integrative Review

    Ibiyemi Oke1, Ruoning Ni1 and Bharat Kumar2, 1UNVERSITY OF IOWA HOSPITALS AND CLINICS, Iowa City, IA, 2University of Iowa Hospitals and Clinics, Iowa City, IA

    Background/Purpose: Shared decision-making (SDM) is a process in which patients and clinicians work together to make health care decisions.  Purposeful SDM (PSDM) is a problem-based…
  • Abstract Number: 0379 • ACR Convergence 2024

    Effectiveness and Safety of Baricitinib for the Treatment of Juvenile Idiopathic Arthritis Associated Uveitis or Chronic Anterior Antinuclear Antibody Positive Uveitis in Children

    Athimalaipet Ramanan1, Catherine Guly2, Gabriele Simonini3, Stuart Keller4, Priyanka Sen4, Thorsten Holzkaemper4 and PIERRE QUARTIER5, 1Bristol Royal Hosp for Children, Bristol, United Kingdom, 2University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom, 3Meyer Children’s Hospital IRCCS; University of Florence, Florence, Toscana, Italy, 4Eli Lilly and Company, Indianapolis, IN, 5Université Paris-Cite, IMAGINE Institute, Necker Children’s Hospital, Paris Cedex 15, France

    Background/Purpose: Baricitinib could target multiple cytokine pathways associated with juvenile idiopathic arthritis associated uveitis (JIA-U) and antinuclear antibody (ANA)-positive uveitis, providing a novel therapeutic approach.…
  • Abstract Number: 0378 • ACR Convergence 2024

    Disparate Disease Activity Outcomes Associated with Demographic Variables in Patients with Juvenile Idiopathic Arthritis in the Pediatric Rheumatology Care and Outcomes Improvement Network Registry

    Julia Harris1, Catherine Bingham2, Sheetal Vora3, Cagri Yildirim-Toruner4, Kerry Ferraro5, Erik Friedrichsen6, Michelle Batthish7, Jon Burnham8, Danielle Fair9, Suhas Ganguli10, Mileka Gilbert11, Beth Gottlieb12, Tzielan Lee13, Daniel Lovell14, Melissa Mannion15, Edward Oberle16, Nancy Pan17, Linda Ray18, Michael Shishov19, Mary Toth20 and Esi Morgan21, 1Children's Mercy Kansas City, Overland Park, KS, 2Penn State Children’s Hospital, Hershey, 3Atrium Health Levine Children's Hospital, Charlotte, NC, 4Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, 5JIA parent and CHOP volunteer, Lower Gwynedd, PA, 6Seattle Children's Hospital, Seattle, 7McMaster Children's Hospital, Hamilton, ON, Canada, 8Children's Hospital of Philadelphia, Philadelphia, PA, 9Medical College of Wisconsin/Children's Wisconsin, Wauwatosa, WI, 10Hackensack University Medical Center, Hackensack, 11Medical University of South Carolina, Charleston, SC, 12Cohen Children's Medical Center, Lake Success, NY, 13Stanford University School of Medicine, Palo Alto, CA, 14Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 15University of Alabama at Birmingham, Birmingham, AL, 16Nationwide Children's Hospital, Columbus, OH, 17Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 18University of Mississippi Medical Center, Jackson, MS, 19Phoenix Children's Hospital, Phoenix, AZ, 20Nemours Foundation, Orlando, FL, 21Seattle Children's Hospital, Seattle, WA

    Background/Purpose: The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a North American learning health network focused on improving outcomes in patients with juvenile…
  • Abstract Number: 0381 • ACR Convergence 2024

    Two- and 3-Year Outcomes of the Childhood Arthritis and Rheumatology Research Alliance FROST Study of New-onset Systemic JIA Treatment

    Timothy Hahn1, George Tomlinson2, Yukiko Kimura3, Vincent Del Gaizo4, Carlos Valdes5 and Timothy Beukelman6, and for the CARRA FROST Investigators, 1Penn State Childrens Hospital, Hershey, PA, 2University of Toronto, Toronto, ON, Canada, 3Hackensack Meridian School of Medicine, New York, NY, 4Childhood Arthritis & Rheumatology Research Alliance (CARRA), Whitehouse Station, NJ, 5Genentech, Davie, FL, 6University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: The FiRst Line Options for sJIA Treatment (FROST) trial was a prospective observational study designed to compare the effectiveness of 4 Childhood Arthritis and…
  • Abstract Number: 0370 • ACR Convergence 2024

    Adolescents’ and Providers’ Perceptions of the Transition from Pediatric to Adult Rheumatology

    Julia Witowska, Brett Curtis, Melanie Donahue, Sara Platte, Rebecca Northway and Jacqueline Madison, University of Michigan, Ann Arbor, MI

    Background/Purpose: The transition from pediatric to adult rheumatology is a vulnerable period for adolescents and is associated with greater disease burden. Adolescents require an organized…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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