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  • Abstract Number: 70 • 2014 ACR/ARHP Annual Meeting

    The Odds of Work Disability, Unemployment and Depending on Living Allowances Are More Influenced By the Number of Morbidities Than By the Presence of a Musculoskeletal Disease

    Antje van der Zee-Neuen1, Polina Putrik2, Sofia Ramiro3, Andras Keszei4, Rob de Bie5, Astrid M. Chorus6 and Annelies Boonen7, 1Internal Medicine, Rheumatology, Maastricht University, Maastricht, Netherlands, 2Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 3Rheumatology, Amsterdam Rheumatology Center, University of Amsterdam & Hospital Garcia de Orta, Almada, Portugal, Amsterdam, Netherlands, 4Medical Informatics, RWTH Aachen University, Aachen, Germany, 5Epidemiology, Maastricht University, Maastricht, Netherlands, 6Netherlands Organization for Applied Scientific Research, Leiden, Netherlands, 7Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands

    Background/Purpose:  The prevalence of multimorbidity (≥ 2 chronic morbidities in 1 person), is increasingly common also in patients at working age. Musculoskeletal diseases (MSKD) are…
  • Abstract Number: 69 • 2014 ACR/ARHP Annual Meeting

    Assessment of Exercise Status in Routine Care Using Patient Reported Outcomes: Initiating Exercise Is Associated with Better Outcomes Than No Exercise

    Isabel Castrejón1, Selda Celik2, Theodore Pincus1 and Yusuf Yazici3, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Rheumatology, NYU School of Medicine, New York, NY, 3Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY

    Background/Purpose: Extensive evidence indicates major benefits of exercise in rheumatoid arthritis1 and many other rheumatic diseases,2 not only for cardiovascular and general fitness, but also for…
  • Abstract Number: 68 • 2014 ACR/ARHP Annual Meeting

    Physical Inactivity to Activity Associated with Less Decline in Physical Function

    Abigail Gilbert1, Jing Song2, Pamela A. Semanik3, Rowland W. Chang4 and Dorothy D. Dunlop2, 1Rheumatology, Northwestern University, Chicago, IL, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Northwestern University, Chicago, IL, 4Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Regular physical activity has been demonstrated to improve quality of life for adults with chronic disease including osteoarthritis. Despite these benefits, half of adults…
  • Abstract Number: 67 • 2014 ACR/ARHP Annual Meeting

    Effects of Exercise on Depressive Symptoms in Adults with Arthritis: A Systematic Review with Meta-Analysis

    George A. Kelley1, Kristi S. Kelley1 and Jennifer Hootman2, 1Biostatistics, West Virginia University, Morgantown, WV, 2Population Health, Centers for Disease Control and Prevention, Atlanta, GA

    Background/Purpose: Previous randomized controlled trials have led to conflicting findings regarding the effects of exercise on depressive symptoms in adults with arthritis and other rheumatic…
  • Abstract Number: 66 • 2014 ACR/ARHP Annual Meeting

    Association of Knee Osteoarthritis and Limitations in Physical Function in a Rural Chinese Population: The Wuchuan OA Study

    Xu Wu1, Jingbo Niu2, Yan Ke3, Qiang LIU4, Xu Tang Sr.5, Zhengming Cao3, Rujun Li3, Hu Li3, Kai Wang3, Xin Zhi3, Daniel White6 and Jian Hao Lin5, 1Peking University People's Hospital Arthritis Clinic & Research Center, Peking University Health Science Center, Beijing, China, 2Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, 3Peking University People’s Hospital, Beijing, China, 4Arthritis Clinical and Reserch Center, Peking University People's Hospital, Peking University Health Science Center, Beijing, China, 5Peking University Health Science Center, Beijing, China, 6Clinical Epidemiology Training, Boston Univ School of Med, Boston, MA

    Background/Purpose knee osteoarthritis (OA) causes more limitations in physical function than other chronic conditions in Caucasians.  Knee OA is known to be more prevalent among…
  • Abstract Number: 65 • 2014 ACR/ARHP Annual Meeting

    Impact of Dropout and Total Knee Replacement on Joint Space Narrowing Estimation: Data from Osteoarthritis Initiaive

    Jamie E. Collins and Elena Losina, Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA

    Impact of dropout and TKR on Joint Space Narrowing estimation: data from Osteoarthritis InitiativeBackground/Purpose: Structural progression in knee osteoarthritis (OA) is often measured by Joint…
  • Abstract Number: 63 • 2014 ACR/ARHP Annual Meeting

    Spine Osteoarthritis Is Associated with All Cause Mortality in Older Men

    Charline Estublier1, Roland Chapurlat2 and Pawel Szulc3, 1Rheumatology, Hôpital Edouard Herriot, Pavillon F, Lyon, France, 2Pavillon F Rheumatology, Hopital Edouard Herriot, Lyon, France, 3Epidemiology of Osteoporosis, INSERM UMR 1033, Lyon, France

    Background/Purpose: Hip and knee osteoarthritis (OA) was associated with higher cardiovascular morbidity and mortality. Data on the cardiovascular status in men with spine OA are…
  • Abstract Number: 62 • 2014 ACR/ARHP Annual Meeting

    Severe Spine Osteoarthritis in Older Men Is Associated with the Risk of Incident Fragility Fracture

    Roland Chapurlat1, Charline Estublier2 and Pawel Szulc3, 1Pavillon F Rheumatology, Hopital Edouard Herriot, Lyon, France, 2Rheumatology, Hôpital Edouard Herriot, Pavillon F, Lyon, France, 3Epidemiology of Osteoporosis, INSERM UMR 1033, Lyon, France

    Background/Purpose: Data on the association of osteoarthritis (OA) with bone fragility are limited. In particular, data on the fracture risk in older men with spine…
  • Abstract Number: 64 • 2014 ACR/ARHP Annual Meeting

    Effect of Family Support on Short-and Intermediate Term Pain and Function Outcomes after Knee or Hip Replacement

    Jasvinder A. Singh1, Kenneth G. Saag2, Celeste Lemay3, Jeroan Allison4 and Patricia D. Franklin5, 1University of Alabama at Birmingham, Birmingham, AL, 2Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, 3University of Massachusetts Medical School, Worchester, MA, 4Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, 5Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA

    Background/Purpose: Patients who undergo total knee replacement (TKR) and total hip replacement (THR) need significant help in the immediate post-operative period, when discharged to home.…
  • Abstract Number: 40 • 2014 ACR/ARHP Annual Meeting

    Prevalence of Spondyloarthritis (ASAS Criteria) in First-Degree Relatives of Patients with Ankylosing Spondylitis

    Raúl Menor Almagro1, Carmen Ordas2, Carlos Montilla3, Jose Luis Alvarez-Vega4, Íñigo Hernández-Rodríguez5, Montserrat Corteguera6, Santiago MuÑoz Fernandez7, Claudia Urrego8, Rafael Ariza-Ariza9, Mireia Moreno10, Xavier Juanola11, Maria Isabel Tévar12, Eduardo Collantes- Estevez13, Juan Mulero- Mendoza14 and Ana Ruiz-Zorrilla15, 1Rheumatology, Hospital de Jerez, Jerez de la Frontera, Spain, 2Hospital de Cabueñes, Gijón, Spain, 3Rheumatology, Hospital Clínico Universitario de Salamanca, Salamanca, Spain, 4H. de Salamanca, Salamanca, Spain, 5Rheumatology, University Hospital Complex of Vigo, Vigo, Spain, 6Hospital Nª Sª Sonsoles, Avila, Spain, 7Sección de Reumatología, Hospital Universitario Infanta Sofía, San Sebastián de los Reyes, Madrid, Spain, 8Hospital G. Segovia, Segovia, Spain, 9Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, 10Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, 11Rheumatology, University Hospital Bellvitge, Barcelona, Spain, 12Hospital Vega Baja, Orihuela, Alicante, Spain, 13Hospital Reina Sofía, Córdoba, Spain, 14Hospital Puerta de Hierro, Madrid, Spain, 15Abbvie, Madrid, Spain

    Background/Purpose: Spondyloarthritis (SpA), a group of inflammatory diseases which exhibit similar genetic background, clinical features and symptoms1, has an estimated prevalence of 0.5-1%2 in Spain.…
  • Abstract Number: 38 • 2014 ACR/ARHP Annual Meeting

    Angiopoietin-like 4 Is over-Expressed in Rheumatoid Arthritis: A Potential Role in Pathological Bone Resorption

    Catherine Swales1, Nick Athanasou2 and Helen Knowles3, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, The Botnar Research Centre, Oxford, United Kingdom, 2Nuffield Orthopaedic Centre, Department of Pathology, Oxford, United Kingdom, 3Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Oxford, United Kingdom

    Background/Purpose In contrast to normal synovial tissue, rheumatoid synovium is hypoxic, and expresses the hypoxia-inducible transcription factors HIF-1α and HIF-2α which allow the transcription of…
  • Abstract Number: 39 • 2014 ACR/ARHP Annual Meeting

    Human CD14+ Monocytes Stimulated with a Combination of TNFα and IL-6 Differentiate into Osteoclast-like Cells with Bone-Resorption Activity

    Kazuhiro Yokota1, Kojiro Sato2, Yoshimi Aizaki2, Yuji Akiyama2 and Toshihide Mimura2, 1Department of Rheumatology & Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, 2Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan

    Background/Purpose Proinflammatory cytokines play an important role in bone destruction in rheumatoid arthritis (RA), as inferred by the efficacy of biologics. Previously, we reported that…
  • Abstract Number: 37 • 2014 ACR/ARHP Annual Meeting

    Regulation of Osteoclast and T Cell Differentiation By DC-STAMP and TRAF3

    Yahui Grace Chiu1, Jinbo Li2, Dongge Li1, Brendan Boyce2 and Christopher T. Ritchlin3, 1Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 2Pathology, University of Rochester, Rochester, NY, 3Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY

    Background/Purpose DC-STAMP (Dendritic Cell-Specific Transmembrane Protein) is a 7-pass transmembrane protein essential for cell-to-cell fusion during OC differentiation. We have previously shown that DC-STAMP is…
  • Abstract Number: 56 • 2014 ACR/ARHP Annual Meeting

    High Prevalence of Cervical Malignant and Premalignant Lesions Among Women with Rheumatoid and Psoriatic Arthritis

    Majed Khraishi1, Rana Aslanov2 and Sarah Khraishi3, 1Nexus Clinical Research, St John's, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, 3NL Research Technologies (NLRT), St. John's, NF, Canada

    Background/Purpose Rheumatic diseases have been associated with an increased prevalence of malignancy. We aimed to examine the prevalence of precancerous lesions and malignancy in the entire…
  • Abstract Number: 55 • 2014 ACR/ARHP Annual Meeting

    Validation of the Diagnosis of Avascular Necrosis of Bone in Administrative Data

    Medha Barbhaiya1, Yan Dong2, Jeffrey A. Sparks1, Elena Losina2, Karen H. Costenbader1 and Jeffrey N. Katz3, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 3Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Avascular necrosis (AVN) of bone is a painful, disabling condition. Studies aimed at improving the diagnosis or treatment of AVN require accurate case-finding methods.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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