ACR Meeting Abstracts

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  • Abstract Number: 406 • 2013 ACR/ARHP Annual Meeting

    Cardiovascular Case Fatality In Rheumatoid Arthritis Is Decreasing; Results From a Current Low Disease Activity Rheumatoid Arthritis Cohort and Review Of The Literature

    Inger L. Meek1, Harald E. Vonkeman2 and Mart A.F.J. van de Laar3, 1Rheumatology & Clinical Immunology, Rheumatology Center Twente, Medisch Spectrum Twente & Twente University, Enschede, Netherlands, 2Medisch Spectrum Twente & University of Twente, Enschede, Netherlands, 3Rheumatology, Medisch Spectrum Twente & University of Twente, Enschede, Netherlands

    Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and mortality. Previous studies, found increased case fatality after myocardial infarction and more frequent…
  • Abstract Number: 407 • 2013 ACR/ARHP Annual Meeting

    Association Between Anti-Cyclic Citrullinated Peptide Antibodies Titres and The Presence and Severity Of Diffuse Interstitial Lung Disease Secondary To Rheumatoid Arthritis

    Juan Manuel Ponce-Guarneros1, Alberto Daniel Rocha Muñoz2, Jorge Ivan Gámez Nava3, Soraya Amalí Zavaleta Muñíz4, Miriam Lizette Díaz Toscano5, Mario Salazar Paramo6, Liliana Faviola De La Cerda Trujillo7, Norma Guadalupe González Montoya3, Ernesto German Cardona Muñoz8, Monica Vazquez del Mercado9 and Laura González López10, 1Medidina Interna-Reumatología, Hospital General Regional 110, Instituto Mexicano del Seguro Social. Guadalajara., Guadalajara, Jalisco, Mexico, 2Institute for Research in Rheumatology and Musculoskeletal System, Guadalajara, Jalisco, Mexico, 3Unidad de Investigación en Epidemiología Clínica, Hospital de Especialidades Centro Médico Nacional de Occidente., Guadalajara, Jalisco, Mexico, 4Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Jalisco, México, Mexico, 5Fisiología, Doctorado en Farmacología, Centro Universitario de Ciencias de la Salud, Guadalajara, Jalisco, Mexico, 6Clinical Research Division, Instituto Mexicano Del SS, Guadalajara, Mexico, 7Unidad de Investigación en Epidemiología Clínica del Hospital de Especialidades Centro Médico Nacional de Occidente, IMSS, Guadalajara, Jalisco, Mexico, 8Departamento de Fisiología, Universidad de Guadalajara, Guadalajara, México, Guadalajara, Jalisco, Mexico, 9Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Mexico, 10Medicina Interna-Reumatología, Departamento de Medicina Interna-Reumatología, Hospital General Regional 110, Instituto Mexicano del Seguro Social., Guadalajara, Jalisco, Mexico

    Background/Purpose: To evaluate the association between anti-cyclic citrullinated peptide antibody titres (anti-CCP) and other clinical factors with the presence and severity of Interstitial Lung Disease…
  • Abstract Number: 408 • 2013 ACR/ARHP Annual Meeting

    Comorbidity In Early Rheumatoid Arthritis.Does Inflammation Matter ?

    Lena Innala1, Clara Sjöberg2, Ewa H. Berglin3, Anna Södergren3, Bozena Möller4, Solbritt M. Rantapaa-Dahlqvist5 and Solveig Wållberg-Jonsson3, 1Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umeå, Sweden, 2Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, 3Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, 4Department of Rheumatology, Sunderby Hospital, Luleå, Sweden, 5Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, Umea, Sweden

    Background/Purpose: Patients with rheumatoid arthritis (RA) suffer from comorbidities that contribute to a shortened lifespan. The degree of inflammation is of importance for the development…
  • Abstract Number: 409 • 2013 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis-Associated Interstitial Lung Disease: Lung Inflammation Evaluated With High Resolution Computed Tomography Scan Is Correlated To Rheumatoid Arthritis Disease Activity

    Jorge Rojas-Serrano1, Renzo Perez-Dorame2, Heidegger Mateos-Toledo2 and Mayra Mejia3, 1Interstitial Lung Diseases Unit, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico, 2Intertitial Lung Disease Unit, Instituto Nacional de Enfermedades Respiratorias, Mexico, Mexico, 3Interstitial Lung Disease Unit, Instituto Nacional de Enfermedades Respiratorias Dr. Ismael Cosío Villegas. México DF., México, D.F., Mexico

    Background/Purpose: To describe the association between rheumatoid arthritis disease activity (RA) and interstitial lung damage (inflammation and fibrosis), in a cohort of rheumatoid arthritis-associated interstitial…
  • Abstract Number: 410 • 2013 ACR/ARHP Annual Meeting

    Correlation of  Carotid Intima Media Thickness With Interleukin-6, Tumor Necrosis Factor-α and Anti-Cyclic Citrullinated Peptides In Rheumatoid Arthritis

    Lourdes Nuñez Atahualpa1, Mauricio Figuroa Sanchez1, Daniel Alberto Rocha Muñoz2, Raul Vargas Ramirez3, Beatriz Teresita Martin Marquez4, Jorge Ivan Gamez Nava5, Laura González López6, Erika Martínez García3, Esther Sanchez Corona3, Marcelo Petri4, Rosa Navarro Hernandez3, Veronica Gonzalez Diaz7, Jorge Aguilar Arreola8, Ana Guisllaine Bernard Medina9, Alejandra Nuñez Atahualpa10, Javier Andrade Garduño10, Eduardo Gomez Bañuelos3 and Monica Vazquez Del Mercado4,8, 1Radiology, Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, 2Unidad de Investigación en Epidemiología Clínica del Hospital de Especialidades Centro Médico Nacional de Occidente, IMSS, Guadalajara, Jalisco, Mexico, 3CUCS, Universidad de Guadalajara, Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético,, Guadalajara, Mexico, 4Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Mexico, 5Unidad de Investigación en Epidemiología Clínica, Hospital de Especialidades Centro Médico Nacional de Occidente., Guadalajara, Jalisco, Mexico, 6Medicina Interna-Reumatología, Departamento de Medicina Interna-Reumatología, Hospital General Regional 110, Instituto Mexicano del Seguro Social., Guadalajara, Jalisco, Mexico, 7Reumatologia, Antiguo Hospital Civil de Guadalajara - Fray Antonio Alcalde, Guadalajara, Mexico, 8Rheumatology, Hospital Civil Dr Juan I Menchaca, Guadalajara, Mexico, 9Rheumatology, Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, 10Universidad Autónoma de Guadalajara, Guadalajara, Mexico

    Background/Purpose: The main cause of death in rheumatoid arthritis patients are cardiovascular events which cannot be entirely explained by traditional risk factors, suggesting, that systemic…
  • Abstract Number: 411 • 2013 ACR/ARHP Annual Meeting

    Differential Effects of biologics On The Removal Of Amyloid Deposition Between The Kidney and Gastric Tract Of Amyloid A Amyloidosis Patients With Rheumatoid Arthritis

    Hiroshi Uda1, Tamaki Harada2, Ayumi Matsumoto3, Aya Mizumoto2, Toshirou Takama2 and Osamu Saiki1, 1Rheumatology, Higashiosaka City General Hospital, Higashiosaka, Japan, 2Nephrology, Higashiosaka City General Hospital, Higashiosaka, Japan, 3Higashiosaka City General Hospital, Higashiosaka, Japan

    Background/Purpose: Several biologics therapy reportedly regress gastric amyloid deposition in amyloid A (AA) amyloidosis patients with rheumatoid arthritis (RA), but it is uncertain whether the…
  • Abstract Number: 413 • 2013 ACR/ARHP Annual Meeting

    A Multiple Cause-Of-Death Study In Rheumatoid Arthritis

    Frederico A. G. Pinheiro1, Deborah C. C. Souza1 and Emilia I. Sato2, 1Rheumatology, Universidade Federal de São Paulo, São Paulo, Brazil, 2Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

    Background/Purpose: Rheumatoid arthritis (RA) is the most common chronic inflammatory arthritis and has a high standardized mortality ratio when compared to general population. One of…
  • Abstract Number: 414 • 2013 ACR/ARHP Annual Meeting

    High Prevalence Of Obesity Among Early and Established Rheumatoid Arthritis

    Ines Colmegna1, Maria Celia Bazan Bardales2, Susan J. Bartlett3 and Carol A. Hitchon4, 1Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 2Rheumatology, McGill University, Montreal, QC, Canada, 3Clinical Epidemiology, McGill University, Montreal, QC, Canada, 4Rheumatology, University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by early, accelerated atherosclerosis leading to increased disability, morbidity and mortality. Inflammation and traditional cardiovascular (CVD) risk factors contribute…
  • Abstract Number: 415 • 2013 ACR/ARHP Annual Meeting

    Stability Of Carotid Intima Media Thickness and No Plaque Formation In Inflammatory Arthritis Patients On Biologics Over One Year

    Stephanie O. Keeling1, Asvina Bissonauth2, Jeff Odenbach2, Quazi Ibrahim3 and Michael Sean McMurtry4, 1Division of Rheumatology, Department of Medicine, University of Alberta, Canada, Edmonton, AB, Canada, 2Medicine, University of Alberta, Edmonton, AB, Canada, 3Medicine, EPICORE, Edmonton, AB, Canada, 4Cardiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Carotid intima media (cIMT) measurement is a validated surrogate measure of cardiovascular (CV) disease. Our aim was to evaluate baseline and follow-up cIMTs in…
  • Abstract Number: 416 • 2013 ACR/ARHP Annual Meeting

    Changes In Body Composition On Two Different Glucocorticoid Regimens In Early RA: Experience From The Cobra-Light Trial

    Nicole P.C. Konijn1, Karin Britsemmer2, Marieke M. ter Wee1, Debby den Uyl1, Birgit S. Blomjous1, Maarten Boers3,4, Dirkjan van Schaardenburg5,6, Willem F. Lems1,6 and Michael T Nurmohamed5,7, 1Rheumatology, VU University Medical Center, Amsterdam, Netherlands, 2Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 3Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, Netherlands, 4Deapartment of Epidemiology and Biostatistics, Jan van Breemen Research Institute/Reade, Amsterdam, Netherlands, 5VU University Medical Center, Amsterdam, Netherlands, 6Jan van Breemen Research Institute/Reade, Amsterdam, Netherlands, 7Rheumatology, Jan van Breemen Research Institute/Reade, Amsterdam, Netherlands

    Background/Purpose: Prednisolone improves joint inflammation and disease severity in rheumatoid arthritis (RA), but is associated with multiple cardiovascular, metabolic and endocrine side effects and may…
  • Abstract Number: 417 • 2013 ACR/ARHP Annual Meeting

    Consensus Statement On The Diagnosis and Management Of Comorbidity In Rheumatoid Arthritis

    Cristina Lajas1, José Luis Andreu2, Alejandro Balsa3, Manuel Crespo4, Carlos M. Gonzalez5, Oscar Illera6, Juan A. Jover1, Isabel Mateo7, Javier Orte8, Javier Rivera9, Jose M Rodriguez-Heredia10, Fredeswinda I. Romero11, Juan A Martínez-López12, Ana M. Ortiz13, Esther Toledano1, Virginia Villaverde14, Estibaliz Loza15, Loreto Carmona16,17 and Santos Castañeda18, 1Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 2Rheumatology, Puerta de Hierro Universitary Hospital, Madrid, Spain, 3Rheumatology unit, La Paz University Hospital, Rheumatology, Madrid, Spain, 4Hospital universitario Severo Ochoa, Madrid, Spain, 5Rheumatology, Gregorio Marañon Hospital, Madrid, Spain, 6Rheumatology, Hospital Infanta Sofía, Madrid, Spain, 7Servicio De Reumatología, Hospital 12 De Octubre,, Madrid, Spain, 8Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, 9Instituto Provincial de Rehabilitación, Madrid, Spain, 10Hospital Universitario de Getafe, Getafe, Spain, 11Section for Autoimmune Diseases, Rheumatology, Jiménez Díaz Foundation University Hospital, Madrid, Spain, 12Rheumatology, Section for Autoimmune Diseases, Jiménez Díaz Foundation University Hospital, Madrid, Spain, 13Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 14Rheumatology, Hospital Universitario de Móstoles, Mostoles, Spain, 15Institu, Madrid, Spain, 16Institute for Musculoskeletal Health, Madrid, Spain, 17Health Sciences School, Universidad Camilo José Cela, Villanueva de la Cañada, Spain, 18Rheumatology, Hospital Universitario de La Princesa, IIS Princesa, Madrid, Spain

    Background/Purpose: comorbidity in rheumatoid arthritis (RA) is very important because it might delay diagnosis and influence treatment decisions. It is usually related to complications, alters…
  • Abstract Number: 418 • 2013 ACR/ARHP Annual Meeting

    Assessment Of Treatment Effect Over Insulin Resistance and Adipokines In Patients With Early Rheumatoid Arthritis: A 6 Months Longitudinal Observational Study

    Sara Manrique-Arija1, José Rioja2, Pedro Valdivielso2, María América López-Lasanta3, Pilar Espiño4, Inmaculada Ureña5, Francisco G. Jiménez-Núñez5, Carmen M. Romero-Barco5 and Antonio Fernández-Nebro1, 1Rheumatology, Hospital Carlos Haya. University of Malaga. IBIMA, Malaga, Spain, 2Department of Medicine. University of Malaga, Malaga, Spain, 3Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, 4Hospital Carlos Haya. University of Malaga, Malaga, Spain, 5Rheumatology, Hospital Carlos Haya. University of Malaga, Malaga, Spain

    Background/Purpose: To analyze treatment effects over insulin resistance (IR), adipokines, inflammatory cytokines and clinical and laboratory characteristics in patients with early rheumatoid arthritis (RA). Methods:…
  • Abstract Number: 419 • 2013 ACR/ARHP Annual Meeting

    A Long Term Observation Of Rheumatoid Arthritis Who Developed Methotrexate Related Lymphoproliferative Disorders

    Yukiko Kamogawa1, Kyohei Nakamura2, Ryu Watanabe2, Tsuyoshi Shirai1, Yoko Fujita3, Yuko Shirota4, Noriko Fukuhara1, Hiroshi Fujii2, Shinichiro Saito5, Tomonori Ishii2 and Hideo Harigae2, 1Tohoku University, Sendai, Japan, 2Department of Hematology and Rheumatology, Tohoku University, Sendai, Japan, 3Department of Hematolgy and rheumatolgy, Tohoku University, Sendai, Japan, 4Department of Hematology and Rheumatolgy, Tohoku University, Sendai, Japan, 5Department of hematology and rheumatology, Tohoku University, Sendai, Japan

    Background/Purpose: Methotrexate (MTX) has been increasingly administered by patients with rheumatoid arthritis (RA). In rare cases, we experience development of malignant lymphoma in patients treated…
  • Abstract Number: 382 • 2013 ACR/ARHP Annual Meeting

    Effect Of Biologic Disease Modifiers On Cardiovascular Risk Of Patients With Rheumatoid Arthritis – 2 Years Prospective Cohort Study

    Majed M. Khraishi1 and Rana Aslanov2, 1Nexus Clinical Research, St John's, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada

    Background/Purpose: People with RA have a higher risk for developing cardiovascular diseases than the general population. The pathogenic mechanisms in RA appear to be complex…
  • Abstract Number: 380 • 2013 ACR/ARHP Annual Meeting

    Active Rheumatoid Arthritis Is An Independent Risk Factor Of Chronic Kidney Disease

    Ryosuke Hanaoka1,2, Kazuhiro Kurasawa3, Ayae Tanaka4 and Harutsugu Okada5, 1Department of Rheumatology, Kamitsuga General Hospital, Kanuma, Japan, 2Department of Rheumatology, Kamitsuga General Hospital, Kanuma, Tochigi, Japan, 3Clinical Immunology, Dokkyo Medical University, Mibu-machi, Shimotsuga-gun, Tochigi-ken, Japan, 4Clinical Immunology, Dokkyo Medical University, Mibu, Tochigi, Japan, 5Clinical Immunology, Dokkyo Medical University, Mibu-machi, Tochigi-ken, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is a systemic inflammatory disease that affects not only joints but also many organs. RA causes vascular damages to contribute to…
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