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  • Abstract Number: 282 • 2014 ACR/ARHP Annual Meeting

    Pharmacovigilance in Juvenile Idiopathic Arthritis Patients (PHARMACHILD) Treated with Biologic Agents and/or Methotrexate. Consolidated Baseline Characteristics from Pharmachild and Other National Registries

    Joost F. Swart1, Alessandro Consolaro2, Gerd Horneff3, Kimme L. Hyrich4, Francesca Bovis5, Bo Magnusson6, Jose Melo-Gomes7, Ekaterina Alexeeva8, Stefano Lanni9, Gerd Ganser10, Violeta Vladislava Panaviene11, Jordi Anton12, Ivan Foeldvari13, Valda Stanevicha14, Susan Nielsen15, Ralf Trauzeddel16, Constantin Ailioaie17, Pierre Quartier18, Toni Hospach19, Gordana Susic20, Maria Trachana21, Frank Weller-Heinemann22, Alberto Martini23, Nico Wulffraat24 and Nicolino Ruperto25, 1Pediatric Rheumatology, Wilhelmina Children's Hospital/ UMC Utrecht, Utrecht, Netherlands, 2Pediatria II, Istituto Giannina Gaslini, Genova, Italy, 3Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 4Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 5Pediatria II, PRINTO, PRINTO - Istituto Giannina Gaslini, Genoa, Italy, 6Pediatric Rheumatology, Karolinska University Hospital, Stockholm, Sweden, 7Pediatric Rheumatology, Lisbon, Portugal, 8Scientific Centre of Children’s Health of RAMS, Moscow, Russia, 9Pediatria II, Istituto Giannina Gaslini, Genoa, Italy, 10Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, 11Children‘s Hospital, Affiliate of Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania, 12Hospital Sant Joan de Déu, Barcelona, Spain, 13Department of Pediatric Rheumatology, Hamburger Zentrum für Kinder und Jugendrheumatologie, Hamburg, Germany, 14Department of Paediatrics, Riga Stradins University, Riga, Latvia, 15University Clinic of Pediatrics II, Rigshospitalet, Copenhagen, Denmark, 16Pediatrics, Helios Clinics, Berlin, Germany, 17Department of Medical Physics, Alexandru Ioan Cuza University, Iasi, Romania, 18Necker-Enfants Malades Hospital, Paris, France, 19Pediatric Rheumatology, Olgahospital, Stuttgart, Germany, 20Institute of Rheumatology, School of Medicine, University of Belgrade, Belgrade, Serbia, 21Aristotle University, Thessaloniki, Greece, 22Klinikum Bremen-Mitte, Bremen, Germany, 23PRINTO-IRCCS, Genova, Italy, 24Pediatric rheumatology, Wilhelmina Children's Hospital/ UMC Utrecht, Utrecht, Netherlands, 25Pediatria II,, Istituto Giannina Gaslini, Genoa, Italy

    Background/Purpose The availability of methotrexate (MTX) and biological agents has provided a major change in the treatment of children with juvenile idiopathic arthritis (JIA). However,…
  • Abstract Number: 281 • 2014 ACR/ARHP Annual Meeting

    Retrospective Review of Immobilization Vs. Immediate Resumption of Activity in Patients with Oligoarticular Juvenile Idiopathic Arthritis and Corticosteroid Knee Injections

    Elaine Ramsay1, Heather Benham2, Jenna Tress3, Janille Diaz4 and David D. Sherry3, 1Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2Pediatric Rheumatology, Texas Scottish Rite Hospital for Children, Dallas, TX, 3Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 4Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia,, PA

    Background/Purpose Intraarticular corticosteroid injection (IACI) is one of the most common treatment modalities in oligoarticular Juvenile Idiopathic Arthritis (JIA). There is widespread use of IACI…
  • Abstract Number: 280 • 2014 ACR/ARHP Annual Meeting

    Biologic Treatment of Adult Patients with Juvenile Idiopathic Arthritis Followed in the National Registry

    Katerina Jarosova1, Karel Hejduk2, Michal Uher2 and Jiri Vencovsky, MD, DSc3, 1clinical, Institution of Rheumatology, Prague, Czech Republic, 2Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic, 3Rheumatology, Charles University Institute of Rheumatology, Prague, Czech Republic

    Background/Purpose To analyze the efficacy and safety of biologic agents in adult patients with juvenile idiopathic arthritis (JIA).Methods ATTRA is the Czech national registry of…
  • Abstract Number: 279 • 2014 ACR/ARHP Annual Meeting

    Focus on Patient Reported Outcomes in Juvenile Idiopathic Arthritis: There Is Room to Improve Care

    Alysha Taxter1, Keshia Maughn2, Edward M. Behrens3 and Pamela F. Weiss4, 1Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Pediatric Rheumatology, Childrens Hospital of Philadelphia, Philadelphia, PA, 4Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose National registry cross-sectional data show significant differences in patient-reported outcomes (PROs) across juvenile idiopathic arthritis (JIA) subtypes. This study aimed to assess predictors of…
  • Abstract Number: 278 • 2014 ACR/ARHP Annual Meeting

    Is It Worth Allowing the Presence of Morning Stiffness in the Definition of Inactive Disease in Juvenile Idiopathic Arthritis?

    Alessandro Consolaro1, Maddalena Allegra2, Maria C. Gallo1, Benedetta Schiappapietra2, Serena Calandra1, Cristina Robbiano2, Federica Mongelli3, Cecilia Bava3, Alberto Martini2,3 and Angelo Ravelli4,5, 1Pediatria II, Istituto Giannina Gaslini, Genova, Italy, 2Istituto Giannina Gaslini, Genova, Italy, 3University of Genova, Genova, Italy, 4Istituto Gaslini-PRINTO, Genova, Italy, 5Istituto Giannina Gaslini and University of Genova, Genova, Italy

    Background/Purpose Morning stiffness is a major symptom of juvenile idiopathic arthritis (JIA) and it is usually associated with active disease. However, it is common view…
  • Abstract Number: 297 • 2014 ACR/ARHP Annual Meeting

    S100 Proteins in Oligoarticular Juvenile Idiopathic Arthritis

    Alexandra R Aminoff1, Carol A Wallace1, Sarah Ringold2, Anne Stevens3 and Jessica M Foster4, 1Pediatric Rheumatology, Seattle Children's Hospital/Univ of Washington, Seattle, WA, 2Pediatrics, Seattle Children's Hospital/Univ of Washington, Seattle, WA, 3Seattle Children's Res Inst, Seattle Children's Hospital, Seattle, WA, 4Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA

    Background/Purpose   There is a lack of reliable biomarkers that correlate with active juvenile idiopathic arthritis (JIA). The S100A8/A9 heterodimer (calprotectin) and S100A12 are proinflammatory…
  • Abstract Number: 296 • 2014 ACR/ARHP Annual Meeting

    Countermeasures Against Methotrexate Intolerance in Juvenile Idiopathic Arthritis Instituted By Parents Show No Effect

    Andrea Scheuern1, Nadine Fischer2, Johannes-Peter Haas1 and Boris Hugle1, 1German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany, 2Research, German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany

    Background/Purpose: Methotrexate (MTX) is the mainstay treatment in the therapy of children with juvenile idiopathic arthritis (JIA) and can lead to prolonged remission and improved…
  • Abstract Number: 295 • 2014 ACR/ARHP Annual Meeting

    Intra-Articular Corticosteroid Injections in Juvenile Idiopathic Arthritis:   Results from a UK Prospective Collaborative Study

    Eileen Baildam1, Roberto Carrasco2, Susannah Holt3, Helen Foster4, Lucy R. Wedderburn5, Alice Chieng6, Joyce Davidson7, Yiannis Ioannou8, Kimme L. Hyrich9 and Wendy Thomson10, 1Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 2Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, 3Paediatric Palliative Care, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 4Newcastle University Medical School, Professor of Paediatric Rheumatology, Newcastle Upon Tyne, United Kingdom, 5Arthritis Research UK Centre for Adolescent Rheumatology,, UCL, UCLH, GOSH NHS Trust, London, United Kingdom, 6Paediatric Rheumatology, Royal Manchester Children's Hospital, Manchester, United Kingdom, 7Royal Hospital for Sick Children, Glasgow, United Kingdom, 8Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom, 9Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 10Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom

    Background/Purpose Intra-articular corticosteroid injections (IACI) are a standard treatment in juvenile idiopathic arthritis (JIA). This study assessed response to IACI in a large prospective cohort…
  • Abstract Number: 294 • 2014 ACR/ARHP Annual Meeting

    Long-Term Pharmacokinetics of Body Surface Area-Adjusted Doses of Golimumab Following Repeated Subcutaneous Administrations in Pediatric Patients with Polyarticular Juvenile Idiopathic Arthritis

    Jocelyn H. Leu1, Alan M. Mendelsohn2, Joyce Ford1, Hugh M. Davis1, Honghui Zhou1 and Zhenhua Xu1, 1Janssen Research & Development, LLC., Spring House, PA, 2Immunology, Janssen Research & Development, LLC., Spring House, PA

    Background/Purpose: To assess the pharmacokinetics (PK) and PK-efficacy correlations  of body surface area (BSA)-adjusted dosing of 30 mg/m2 golimumab administered subcutaneously (SC) every 4 weeks…
  • Abstract Number: 293 • 2014 ACR/ARHP Annual Meeting

    Long Term Functional Outcome and Quality of Life of Patients with Refractory Juvenile Idiopathic Arthritis Treated with Etanercept: Results of the Dutch Arthritis and Biologicals in Children Register

    Janneke Anink1, Femke Prince1, Maryanne Dijkstra1, Marieke H. Otten1, Marinka Twilt2, Rebecca ten Cate3, Simone Gorter4, Yvonne Koopman-Keemink5, Marion A.J. Van Rossum6,7, Esther P.A. Hoppenreijs8,9 and Lisette W.A. van Suijlekom-Smit1, 1Pediatric Rheumatology, Erasmus MC Sophia Children's Hospital, Rotterdam, Netherlands, 2Pediatric Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 3Pediatric Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Department of Internal Medicine, division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 5Pediatric Rheumatology, Hagaziekenhuis Juliana Children's Hospital, The Hague, Netherlands, 6Pediatric Rheumatology, Reade, location Jan van Breemen, Amsterdam, Netherlands, 7Pediatric Rheumatology, Emma Kinderziekenhuis Academic Medical Center, Amsterdam, Netherlands, 8Pediatric Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 9Pediatric Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands

    Background/Purpose: Juvenile idiopathic arthritis patients refractory to methotrexate are eligible for treatment with biologic agents. A longitudinal sub-analysis (n=53) of the Dutch Arthritis and Biologicals…
  • Abstract Number: 292 • 2014 ACR/ARHP Annual Meeting

    Flares in Children with JIA: Results from the Reacch-out Cohort

    Lori B. Tucker1, Jaime Guzman1, Kiem Oen2 and ReACCh Out Investigators3, 1Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 2Pediatrics, Children's Hospital of Winnipeg and University of Manitoba, Winnipeg, MB, Canada, 3BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose:   Disease flares are a concern to patients with JIA, their parents, and caregivers alike; but little is known of disease manifestations during a…
  • Abstract Number: 291 • 2014 ACR/ARHP Annual Meeting

    Development of a Serious Game Designed for Children with Juvenile Idiopathic Arthritis

    Jean-David Cohen1, Damien Bentayou2, Marcantoine Bernard-Brunel3 and Sonia Tropé4, 1IMMUNO-RHEUMATOLOGY, CHU LAPEYRONIE, MONTPELLIER, France, 2Art Director, CG Artist, PESSAC, France, 3Programmer, CG Artist, PESSAC, France, 4149 avenue du Maine, ANDAR, Paris, France

    Background/Purpose Juvenile Idiopathic Arthritis (JIA) is the most common chronic paediatric rheumatic disease and cause of physical and psychological disability, with family and school consequences.…
  • Abstract Number: 290 • 2014 ACR/ARHP Annual Meeting

    Patterns of Active Joint Involvement in JIA

    Simon W.M. Eng1, Mira Van Veenendaal2, Alan M. Rosenberg3, Kiem Oen4, Quaid Morris1 and Rae S.M. Yeung2, 1University of Toronto, Toronto, ON, Canada, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, 4Pediatrics RR149 Rehab Ctr, University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: JIA encompasses a set of heterogeneous diseases with chronic joint inflammation. Although the ILAR criteria consider joint counts, they do not reflect specific joint…
  • Abstract Number: 289 • 2014 ACR/ARHP Annual Meeting

    Patient-Reported Outcomes in Children with Moderately to Severely Active Polyarticular or Polyarticular-Course Juvenile Idiopathic Arthritis Who Are Prescribed and Treated with Adalimumab

    Gerd Horneff1, Carol A. Wallace2, Pierre Quartier3, Daniel J. Kingsbury4, Kirsten Minden5, Mareike Bereswill6, Vishvas Garg7, Hartmut Kupper6 and Jasmina Kalabic6, 1Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 2University of Washington School of Medicine and Seattle Children's Hospital, Seattle, WA, 3Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 4Randall Children's Hospital at Legacy Emanuel, Portland, OR, 5Kinderklinik der Charite, Otto-Heubner Centrum, Berlin, Germany, 6AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, 7AbbVie Inc., North Chicago, IL

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases of childhood and adolescents, and improvement in health-related quality of life and…
  • Abstract Number: 258 • 2014 ACR/ARHP Annual Meeting

    Pain Characteristics Among Patients with Rheumatoid Arthritis in the Context of Patient-Physician Discordance in Disease Activity Assessments

    John M. Davis III1, Cynthia S. Crowson2, Tim Bongartz1, Clement J. Michet1, Eric L. Matteson1 and Sherine E. Gabriel3, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose Healthcare must be patient-centered to achieve optimal outcomes and quality of life.  From this perspective, it is significant that patients with rheumatoid arthritis (RA)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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