Abstracts Archive - Page 2208 of 2425 - ACR Meeting Abstracts

Abstract Number: 639 • 2013 ACR/ARHP Annual Meeting
Examination Of The Cytokine Profile Of The Cerebrospinal Fluid In Neuropsychiatric Systemic Lupus Erythematosus
Kunihiro Ichinose¹, Takeshi Ushigusa², Yoshikazu Nakashima³, Takahisa Suzuki³, Yoshiro Horai⁴, Shin-ya Kawashiri², Naoki Iwamoto², Mami Tamai³, Kazuhiko Arima⁴, Hideki Nakamura², Tomoki Origuchi⁵ and Atsushi Kawakami⁴, ¹Department of Immunology and Rheumatology, Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁴Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Examination of the cytokine profile of the cerebrospinal fluid in neuropsychiatric systemic lupus erythematosusBackground/Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE) is a serious complication in systemic…
Abstract Number: 640 • 2013 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus Patients With Atherosclerosis Are Characterised By a Distinct Invariant Natural Killer T Cell Phenotype and Altered CD1d-Mediated Lipid Antigen Presentation
Edward Smith¹, Sara Croca², Andrew Pitcher¹, D.A. Isenberg¹, Anisur Rahman³ and Elizabeth C. Jury⁴, ¹Centre for Rheumatology Research, University College London, London, United Kingdom, ²Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, ³Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom, ⁴Division of Medicine, Centre for Rheumatology Research, University College London, London, United Kingdom
Background/Purpose: It is widely reported that systemic lupus erythematosus (SLE) patients have an increased risk of atherosclerosis compared to the general population, irrespective of traditional…
Abstract Number: 641 • 2013 ACR/ARHP Annual Meeting
Vitamin D Increases The Number and Function Of Myeloid Angiogenic Cells In Systemic Lupus Erythematosus
John A. Reynolds¹, David W. Ray², Terence O'Neill³, M. Yvonne Alexander⁴ and Ian N. Bruce⁵, ¹Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, United Kingdom, Manchester, United Kingdom, ²Institute of Human Development, Institute of Human Development, The University of Manchester, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ⁴Healthcare Science Research Institute, Faculty of Science and Engineering, Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, ⁵Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit and NIHR Manchester Musculoskeletal Biomedical Research Unit, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Patients with Systemic Lupus Erythematosus (SLE) have an increased prevalence of cardiovascular disease (CVD). Vitamin D deficiency is common in SLE and an independent…
Abstract Number: 614 • 2013 ACR/ARHP Annual Meeting
Causes Of Mortality In Lupus Patients Followed Prospectively At a Large Single-Centre Lupus Clinic
Barry J. Sheane, Dominique Ibanez, Dafna D. Gladman and Murray B. Urowitz, Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Survival rates of patients with systemic lupus erythematosus (SLE) have improved significantly over the last four decades. Mortality rates remain high, however, and are…
Abstract Number: 602 • 2013 ACR/ARHP Annual Meeting
Repeat Biopsy In Lupus Nephritis: A Single-Center Experience
Josefina Marin¹, Marina Scolnik², Eliana Lancioni³, Gustavo Greloni⁴, Cristian Quiroz⁵, Johana Zacariaz³, Carla Saucedo⁶, Luis J. Catoggio² and Enrique R. Soriano², ¹Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, ³Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Nephrology Service. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: Renal involvement in systemic lupus erythematosus (SLE) is an important cause of morbidity and even mortality. Lupus nephritis has diverse morphologic manifestations with varying clinical…
Abstract Number: 603 • 2013 ACR/ARHP Annual Meeting
Factors Associated With a Double Increase In Serum Creatinine In Biopsy Proven Lupus Nephritis From a Single Center In Spain
Raúl Menor Almagro¹, M. H. Cardiel², Javier Rubio Garrido³, J. Luis de la Iglesia¹, José Javier Perez Venegas¹, María Mar Ruiz Tudela¹, José Javier Salaberri¹ and Manuel Paez-Camino¹, ¹Rheumatology, Hospital de Jerez, Jerez de la Frontera, Spain, ²Centro de Investigacion Clinica de Morelia, Morelia, Mexico, ³Pathology, Hospital de Jerez, Jerez de la Frontera, Spain
Background/Purpose: Lupus nephritis is a common and feared complication in systemic lupus erythematosus (SLE). Clinicians have relied on different variables to help to predict those…
Abstract Number: 604 • 2013 ACR/ARHP Annual Meeting
Mycophenolate Mofetil Is Not Associated With Reduced Cardiovascular Or Lupus Damage Accumulation In a Cross-Sectional Lupus Cohort Study
Maureen A. McMahon¹, Maria Dall'era², Eliza Chakravarty³, Joseph E. Craft⁴, Gary S. Gilkeson⁵, Kenneth C. Kalunian⁶, R. John Looney⁷, Gerald McGwin Jr.⁸ and Meggan Mackay⁹, ¹Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ³Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Yale University School of Medicine, Internal Medicine, Section of Rheumatology, New Haven, CT, ⁵Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ⁶UCSD School of Medicine, La Jolla, CA, ⁷Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁸Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁹Autoimmune & Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Mycophenolate mofetil (MMF) is frequently used for the treatment of lupus. The immune-modulating effects of MMF extend beyond effects on lymphocyte proliferation, and include…
Abstract Number: 605 • 2013 ACR/ARHP Annual Meeting
Childhood Lupus Nephritis: Long Term Outcome Of 91biopsy Proven Cases From India
Puja Srivastava¹, Bonnie Abujam², Ramnath Misra¹, Able Lawrence¹, Vikas Agarwal¹ and Amita Aggarwal¹, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Postgraduate Institute of Medical Education and Research, Chandigarh, India
Background/Purpose: Childhood SLE has a higher prevalence of lupus nephritis (LN) as well as proliferative LN than adults. There is ethnic variation in response to…
Abstract Number: 606 • 2013 ACR/ARHP Annual Meeting
Characteristics Of Lupus Nephritis: Data From a Large Multicenter Registry Of Patients With Systemic Lupus Erythematosus
Diane L. Kamen¹, Graciela S. Alarcon², Jill P. Buyon³, Mary Anne Dooley⁴, Richard A. Furie⁵, David S. Pisetsky⁶ and Tammy O. Utset⁷, ¹Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ²Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, ³Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, ⁴University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵The Feinstein Institute for Medical Research and North Shore-Long Island Jewish Health System, Lake Success, NY, ⁶Department of Medicine, Duke University Medical Center, Durham, NC, ⁷Rheumatology, University of Chicago Medical Center, Chicago, IL
Background/Purpose: Renal disease is strongly associated with morbidity and mortality among SLE patients. We utilized the Lupus Clinical Trials Consortium, Inc. longitudinal registry of SLE…
Abstract Number: 607 • 2013 ACR/ARHP Annual Meeting
Venous Thromboembolic Disease Is Associated With Increased Length Of Stay and In-Hospital Mortality In Hospitalized SLE Patients: A Multi-State, Population-Based Study
Matthew Cascino¹, Laura Trupin¹, Sara Murray¹, Mary Margaretten², Edward H. Yelin³ and Jinoos Yazdany¹, ¹Medicine, University of California, San Francisco, San Francisco, CA, ²Rheumatology, University of California, San Francisco, San Francisco, CA, ³Arthritis Research Group, University of California, San Francisco, San Francisco, CA
Background/Purpose: Individuals with systemic lupus erythematosus (SLE) are at increased risk for venous thromboembolism (VTE). However, there is limited population-based data on outcomes associated with…
Abstract Number: 608 • 2013 ACR/ARHP Annual Meeting
Effect Of Renal Damage On Extra-Renal Organ Damage and Mortality In Patients With Systemic Lupus Erythematosus (SLE): A Longitudinal Cohort Study Of 756 Patients
Chi Chiu Mok¹, Ling Yin Ho¹, Kar Li Chan¹ and Chi Hung To², ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose: To study the effect of renal damage on extra-renal organ damage and mortality in patients with SLE. Methods: Patients who fulfilled >=4 ACR criteria…
Abstract Number: 609 • 2013 ACR/ARHP Annual Meeting
Increased Arterial Stiffness In Systemic Lupus Erythematosus (SLE) Patients At Low Risk For Cardiovascular Disease: A Cross-Sectional Controlled Study
Karim Sacre¹, Brigitte Escoubet², Maria Chauchard³, Antoine Dossier³, Marie-Paule Chauveheid⁴ and Thomas Papo⁵, ¹Internal Medicine, University Paris-7, INSERM U699, APHP, Bichat Hospital, Paris, France, ²Cardiology, University Paris-7, INSERM U872, APHP, Bichat Hospital, Paris, France, ³Internal Medicine, University Paris-7, APHP, Bichat Hospital, Paris, France, ⁴Internal Medicine,, University Paris-7, APHP, Bichat Hospital, Paris, France, ⁵Internal Medicine, Bichat Hospital, Paris, Paris, France
Background/Purpose: Accelerated atherosclerosis accounts for significant premature mortality rates among systemic lupus erythematosus (SLE) patients. Arterial stiffness reflects changes in mechanical properties of vascular wall…
Abstract Number: 610 • 2013 ACR/ARHP Annual Meeting
Disease Specific Quality Of Life Domains Are Impaired In Patients With Lupus Nephritis?
Meenakshi Jolly¹, Zineb Aouhab², Sergio Toloza³, Ana M. Bertoli⁴, Ivana Blazevik⁵, Luis M. Vila⁶, Ioana Moldovan⁷, Karina Marianne D. Torralba⁸, Arif Kaya⁹, Berna Goker¹⁰, Mehmet E. Tezcan¹¹, Seminur Haznedaroglu¹², Josiane Bourré-Tessier¹³, Ann E. Clarke¹⁴, D.J. Wallace¹⁵, Michael H. Weisman¹⁶ and Graciela S. Alarcon¹⁷, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Medicine, John H Stroger Hospital, Chicago, IL, ³Hospital San Juan Bautista, Catamarca, Argentina, ⁴Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, ⁵University of Buenos Aires, Buenos Aries, Argentina, ⁶Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, PR, ⁷Loma Linda Univ Medical Center, Loma Linda, CA, ⁸Rheumatology/Int Med, USC Keck Schl of Medicine, Los Angeles, CA, ⁹Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, ¹⁰Internal Medicine-Rheumatology, Gazi University, Ankara, Turkey, ¹¹Rheumatology, Dr. Lutfi Kirdar Kartal EA Hastanesi, Istanbul, Turkey, ¹²Internal Medicine-Rheumatology, Gazi University School of Medicine, Ankara, Turkey, ¹³Rheumatology, McGill University, Montréal, QC, Canada, ¹⁴Division of Rheumatology, University of Calgary, Alberta, Calgary, AB, Canada, ¹⁵Cedars-Sinai Medical Center, Los Angeles, CA, ¹⁶Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ¹⁷Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Often systemic Lupus Erythematosus (SLE) patients with Lupus Nephritis (LN) require frequent visits with their health care providers, follow up, and exposure to immunosuppressive…
Abstract Number: 611 • 2013 ACR/ARHP Annual Meeting
Efficacy and Safety Of Transjugular Renal Biopsy In Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Retrospective Monocentric Study Of 91 Procedures
Alexis Mathian¹, Maud Cazenave², Laurent Arnaud³, Nathalie Costedoat-Chalumeau⁴, Du Boutin-LE Thi Huong⁵, Ahlem Chaib⁵, Fleur Cohen-Aubart⁶, Julien Haroche³, Miguel Hié⁵, Makoto Miyara⁵, Philippe Rouvier⁷, Jean-Charles Piette⁸, Philippe Cluzel⁹ and Zahir Amoura¹⁰, ¹Hôpital Pitié-Salpêtrière, AP-HP, UPMC Univ Paris 06 & French National Reference Center For Systemic Lupus and Antiphospholipid Syndrome, Internal Medicine, Paris, France, ²Service de médecine interne 2, Centre de référence National pour le Lupus et le Syndrome des antiphospholipides, CHU Pitié-Salpêtrière, APHP, Paris, France, Paris, France, ³Internal Medicine, Hôpital Pitié-Salpêtrière, AP-HP, UPMC Univ Paris 06 & French National Reference Center For Systemic Lupus and Antiphospholipid Syndrome, Paris, France, ⁴Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France, ⁵Hôpital Pitié-Salpêtrière, AP-HP, UPMC Univ Paris 06 & French National Reference Center For Systemic Lupus and Antiphospholipid Syndrome, Paris, France, ⁶Internal Medicine Dpt 2, Pitié-Salpêtrière Hospital, APHP, Paris, France, ⁷Service d'anatomie pathologie, CHU Pitié-Salpêtrière, APHP, Paris, France, Paris, France, ⁸Department of Internal Medicine 1., CHU Pitié-Salpêtrière, Paris, France, ⁹Cadiovascular Imaging and Interventional Radiology, Pitié-Salpétrière, Paris, France, ¹⁰Department of Internal Medicine 2. Referal center for SLE/APS, CHU Pitié-Salpêtrière, Paris, France
Background/Purpose: Percutaneous renal biopsy requires a long duration discontinuation of antithrombotic treatment which can increase the risk of thrombosis in patient with Systemic Lupus Erythematosus…
Abstract Number: 612 • 2013 ACR/ARHP Annual Meeting
Increased Expression Of Membrane Endothelial Protein C Receptor Associates With Poor Response In Lupus Nephritis Independent Of Chronicity Index
Barbara Mendez¹, Ming Wu², Dominick Santoriello², Laura Barisoni³, Peter M. Izmirly¹, Jill P. Buyon¹ and Robert M. Clancy⁴, ¹Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Pathology, New York University School of Medicine, New York, NY, ³Pathology, University of Miami Hospital, Miami, FL, ⁴Medicine, New York University School of Medicine, New York, NY
Background/Purpose: While a consensus is that a high chronicity index (CI) is associated with a greater risk for progression to renal failure in lupus nephritis…

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