Abstracts Archive - Page 2199 of 2425 - ACR Meeting Abstracts

Abstract Number: 749 • 2013 ACR/ARHP Annual Meeting
High Clinical Remission Rate With Relatively High Incidence Of Serious Infection In Newly-Onset ANCA-Associated Vasculitides In Japan – A Report From The Nationwide Prospective Cohort Study
Masayoshi Harigai¹, Ken-ei Sada², Takao Fujii³, Masahiro Yamamura⁴, Yoshihiro Arimura⁵ and Hirofumi Makino², ¹Dept of Pharmacovigilance, Tokyo Medical and Dental University, Tokyo, Japan, ²Department of Medicine and Clinical Science, Okayama University, Okayama, Japan, ³Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁴Center for Rheumatology, Okayama Saiseikai Hospital, Okayama, Japan, ⁵First Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, Japan
Background/Purpose: Clinical characteristics and antineutrophil cytoplasmic antibody (ANCA)-serology of ANCA-associated vasculitis (AAV) patients are substantially different between Western and Asian countries. We investigated effectiveness and…
Abstract Number: 750 • 2013 ACR/ARHP Annual Meeting
Maintenance Treatment In Childhood Granulomatosis With Polyangiitis
Marinka Twilt¹, Rayfel Schneider², Diane Hebert³, Elizabeth Harvey³, Ronald M. Laxer², Sharon Dell⁴, Christoph Licht³ and Susanne M. Benseler², ¹Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ²Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ³Nephrology, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Granulomatosis with Polyangiitis (GPA) is a rare but life threatening disease. Most children present with pulmonary bleeds and/or renal failure. Most treatment regimens are…
Abstract Number: 751 • 2013 ACR/ARHP Annual Meeting
Fatigue, Pain, and Functional Disability Among Patients With Vasculitis
Antoine G. Sreih^1,2, Narender Annapureddy³ and Osama Elsallabi⁴, ¹Medicine/Division of Rheumatology, The University of Pennsylvania, Philadelphia, PA, ²Medicine/Rheumatology, Rush University Medical Center, Chicago, IL, ³Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Medicine, Creighton University, Omaha, NE
Background/Purpose: Vasculitis is a heterogeneous group of diseases often resulting in severe morbidity affecting patients’ quality of life. These morbidities are generally attributed to disease…
Abstract Number: 752 • 2013 ACR/ARHP Annual Meeting
Cardiovascular Outcomes Are Worse In Microscopic Polyangiitis Compared To Granulomatosis With Polyangiitis: Data From An Inception Cohort Of Patients With Anti-Neutrophil Cytoplasm Antibody Associated Systemic Vasculitis
Anna Mistry¹, Joanna Robson², Susan L Hogan³, Caroline Poulton³, Yichun Hu⁴, Ronald Falk⁵ and Raashid A. Luqmani⁶, ¹Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK, Oxford, United Kingdom, ²Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, ³UNC Kidney Center, Chapel Hill, NC, ⁴UNC Kidney Centre, University of North Carolina, Chapel Hill, North Carolina, Chapel Hill, NC, ⁵Dept of Nephrology and Hypertension, UNC Kidney Center, Chapel Hill, NC, ⁶Rheumatology, Nuffield Orthopaedic Centre, Oxford, United Kingdom
Background/Purpose: A greater than three-fold increase in cardiovascular mortality as been reported within the first five years of diagnosis of anti-neutrophil cytoplasmic antibody (ANCA) associated…
Abstract Number: 753 • 2013 ACR/ARHP Annual Meeting
Validation Of The New Histopathological Classification Of ANCA Glomerulonephritis and Its Association With Renal Outcomes In a Paediatric Population
Marinka Twilt¹, Damien Noone², Wesley Hayes², Paul Thorner³, Susanne M. Benseler⁴, Ronald M. Laxer⁴, Rulan Parekh² and Diane Hebert², ¹Pediatric Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ²Nephrology, The Hospital for Sick Children, Toronto, ON, Canada, ³Pathology, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Anti-Neutrophil Cytoplasmic Antibody (ANCA) associated glomerulonephritides (ANCA GN) include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and Churg-Strauss. A novel histopathologic classification for GPA…
Abstract Number: 754 • 2013 ACR/ARHP Annual Meeting
Outcome Of Kidney Transplantation In Paediatric Patients With ANCA Associated Glomerulonephritis: A Single-Center Experience
Marinka Twilt¹, Damien Noone², Wesley Hayes², Paul Thorner³, Susanne M. Benseler⁴, Ronald M. Laxer⁴, Rulan Parekh² and Diane Hebert², ¹Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ²Nephrology, The Hospital for Sick Children, Toronto, ON, Canada, ³Pathology, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Kidney transplant outcomes for paediatric patients with end stage kidney disease (ESKD) secondary to ANCA GN, particularly granulomatosis with polyangiitis (GPA) and microscopic polyangiitis…
Abstract Number: 755 • 2013 ACR/ARHP Annual Meeting
Survival Of Patients With ANCA-Associated Vasculitides In Chronic Dialysis In France From 2002 To 2011: Data From The National Rein Registry
Manon Romeu¹, Cécile Couchoud Sr.², Jean-Christophe Delarozière³, Laurent Chiche Sr.⁴, Jean-Robert Harle⁵, Bertrand Gondoin⁶, Stéphane Burtey⁶, Philippe Brunet⁶, Yvon Berland⁶ and Noémie Jourde-Chiche Sr.⁷, ¹Nephrology, Aix-Marseille Universite, APHM, Marseille, France, ²registre REIN, agence de la biomédecine, paris, France, ³public health, APHM, Marseille, France, ⁴Internal Medicine, CHU Marseille, Marseille, France, ⁵Internal Medicine, APHM, Marseille, France, ⁶Nephrology, APHM, Marseille, France, ⁷Nephrology, Aix-Marseille Université - APHM, Marseille, France
Background/Purpose: Despite dramatic outcome improvement in ANCA-associated vasculitides (AAV), renal involvement is still leading to end-stage renal disease (ESRD) in 20-30% of patients. This study…
Abstract Number: 756 • 2013 ACR/ARHP Annual Meeting
Clinical Value Of Commonly-Measured Laboratory Tests In Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)
Peter C. Grayson¹, Paul A. Monach², David Cuthbertson³, Simon Carette⁴, Gary S. Hoffman⁵, Nader A. Khalidi⁶, C. L. Koening⁷, Carol A. Langford⁸, Kathleen Maksimowicz-McKinnon⁹, Christian Pagnoux¹⁰, Philip Seo¹¹, Ulrich Specks¹², Steven R. Ytterberg¹³ and Peter A. Merkel¹⁴, ¹NIAMS, National Institutes of Health, Bethesda, MD, ²Rheumatology, Boston University, Boston, MA, ³Department of Biostatistics, University of South Florida, Tampa, FL, ⁴Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ⁵Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, ⁶Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, ⁷Internal Medicine, Salt Lake City Veterans Administration, Salt Lake City, UT, ⁸Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, ⁹Rheumatology, Henry Ford Hospital, Detroit, MI, ¹⁰Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, ¹¹Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, ¹²Mayo Clinic, Rochester, MN, ¹³Rheumatology Division, Mayo Clinic, Rochester, MN, ¹⁴Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Serial measurement of absolute eosinophil count (Eos), serum immunoglobulin E (IgE), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) is common practice in the…
Abstract Number: 757 • 2013 ACR/ARHP Annual Meeting
Impact Of Cardiac Magnetic Resonance Imaging On Eosinophilic Granulomatosis With Polyangiitis Outcomes: A Long-Term Retrospective Study On 42 Patients
Bertrand Dunogué¹, Pascal Cohen², Benjamin Terrier³, Julien Marmursztejn⁴, Denis Duboc⁴, Olivier Vignaux⁵ and Loic Guillevin³, ¹Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Paris, France, ²National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Paris, France, ³Internal Medicine, Cochin University Hospital, Paris, France, ⁴Cardiology, Cochin University Hospital, Paris, France, ⁵Radiology, Cochin University Hospital, Paris, France
Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) cardiomyopathy carries a poor prognosis, and is the main cause of 1st-year and long-term mortality. Morbidity due to chronic…
Abstract Number: 758 • 2013 ACR/ARHP Annual Meeting
Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss Syndrome) – Re-Analysis Of The French Vasculitis Study Group Cohort Using Different Disease Definitions and Cluster Analysis
Christian Pagnoux¹, Pascal N. Tyrrell², Chiara Baldini³, Simon Carette¹, Jean-Francois Cordier⁴, Loic Guillevin⁵ and French Vasculitis Study Group FVSG⁶, ¹Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ²Department of Medical Imaging, University of Toronto, Toronto, ON, Canada, ³University of Pisa, Rheumatology Unit, Pisa, Italy, ⁴Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, ⁵Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, ⁶Internal Medicine, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France
Background/Purpose: Because only 25–40% of the patients are ANCA+ and biopsy is not always taken or helpful, EGPA diagnosis can be challenging. Previous cohort analyses…
Abstract Number: 759 • 2013 ACR/ARHP Annual Meeting
Eosinophilic Granulomatosis With Polyangiitis (Churg–Strauss Syndrome): Comparison Of The Independent French Vasculitis Study Group and Italian–Pisa Patient Cohorts and Cross-Validation Of Cluster Analysis
Chiara Baldini¹, Pascal N. Tyrrell², Manuela Latorre³, Simon Carette⁴, Nader A. Khalidi⁵, Veronica Seccia⁶, Loic Guillevin⁷ and Christian Pagnoux⁴, ¹University of Pisa, Rheumatology Unit, Pisa, Italy, ²Department of Medical Imaging, University of Toronto, Toronto, ON, Canada, ³University of Pisa, Pneumology Unit, Pisa, Italy, ⁴Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ⁵Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, ⁶Unit of Otorhinolaryngology, Department of Neuroscience, University of Pisa, Pisa, Italy, Pisa, Italy, ⁷Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France
Background/Purpose: Previous analyses of the FVSG- and Pisa-cohort EGPA patients identified several covariates associated with poor outcomes and suggested differences between ANCA+ and ANCA– EGPA-patient…
Abstract Number: 760 • 2013 ACR/ARHP Annual Meeting
Cluster Analysis To Explore Clinical Subclassification Of Eosinophilic Granulomatosis With Polyangiitis (Churg–Strauss)
Thomas Neumann¹, Frank Moosig², Augusto Vaglio³, Jochen Zwerina⁴, Renato Alberto Sinico⁵, Wojciech Szczeklik⁶, Paolo Bottero⁷, Phillip Bremer⁸, Andrea Gioffredi⁹, Barbara Sokolowska⁶, Luca Di Toma⁵, Federica Maritati⁹, Julian Großkreutz¹⁰, Claus Kroegel¹¹, Matthieu Resche-Rigon¹² and Alfred Mahr¹³, ¹Jena University Hospital, Internal Medicine III, Jena, Germany, ²Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt, Germany, ³Unit of Nephrology, University Hospital of Parma, Parma, Italy, ⁴Ludwig Bolzmann institut of osteology at the 4th medical departmen, Hanusch Hospital, Vienna, Austria, ⁵Clinical Immunology Unit and Renal Unit, Department of Medicine, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milan, Italy, ⁶Department of Medicine, Jagiellonian University Medical College, Krakow, Poland, ⁷llergy and Clinical Immunology Unit, Magenta Hospital, Magenta, Italy, ⁸University Hospital Schleswig Holstein and Klinikum Bad Bramstedt, Bad Bramstedt, Germany, ⁹Department of Clinical Medicine, Nephrology and Health Sciences, University of Parma, Parma, Italy, ¹⁰Department of Neurology, Jena University-Hospital, Jena, Germany, ¹¹Jena University Hospital, Internal Medicine I, Jena, Germany, ¹²Biostatistics, Hopital Saint-Louis, Paris, France, ¹³Department of Internal Medicine, Hospital Saint-Louis, Paris, France
Background/Purpose: Results from descriptive studies of eosinophilic granulomatosis with polyangiitis (EGPA) suggest distinct clinical subclasses that may be determined by anti-neutrophil cytoplasmic antibody (ANCA) status.…
Abstract Number: 761 • 2013 ACR/ARHP Annual Meeting
Apremilast For The Treatment Of Behçet’s Syndrome: A Phase II Randomized, Placebo-Controlled, Double-Blind Study
Gulen Hatemi¹, Melike Melikoglu², Recep Tunc³, Cengiz Korkmaz⁴, Banu Turgut Ozturk⁵, Cem Mat⁶, Peter A. Merkel⁷, Kenneth Calamia⁸, Ziqi Liu⁹, Lilia Pineda⁹, Randall M. Stevens⁹, Hasan Yazici² and Yusuf Yazici¹⁰, ¹Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ²Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ³Necmettin Erbakan University, Meram Medical Faculty,Division of Rheumatology, Konya, Turkey, ⁴Eskisehir Osmangazi University, Eskisehir, Turkey, ⁵Selçuk University, Konya, Turkey, ⁶Istanbul University, Cerrahpasa Medical Faculty, Dermatology, Istanbul, Turkey, ⁷Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA, ⁸Mayo Clinic, Jacksonville, FL, ⁹Celgene Corporation, Warren, NJ, ¹⁰Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY
Apremilast for the Treatment of Behçet's Syndrome: A Phase II Randomized, Placebo-Controlled, Double-Blind StudyBackground/Purpose: Mucocutaneous manifestations of Behçet's syndrome (BS) can be resistant to conventional…
Abstract Number: 762 • 2013 ACR/ARHP Annual Meeting
Inhibition Of TGF-Beta Signaling In Articular Chondrocytes Leads To OA-Like Pathological Defects and Pain-Related Behavior Change In Mice
Jia Li¹, Jie Shen², Shan Li¹, John Dickerson¹, Jeffrey Kroin¹, Hee-Jeong Im¹ and Di Chen¹, ¹Rush University, Chicago, IL, ²University of Rochester, Rochester, NY
Background/Purpose: TGF-β signaling plays an important role in chondrocyte differentiation and osteoarthritis (OA) pathogenesis. However TGF-β downstream target genes and signaling mechanism in OA development…
Abstract Number: 763 • 2013 ACR/ARHP Annual Meeting
The Risk Of Myocardial Infarction In Systemic Sclerosis: A Population-Based Cohort Study
Iman Hemmati¹, Hyon K. Choi^2,3, Kamran Shojania^3,4, Eric C. Sayre³ and J. Antonio Avina-Zubieta^3,5, ¹Deparment of Medicine and Rheumatology, University of British Columbia, Vancouver, BC, Canada, ²Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁴Rheumatology, University of British Columbia, Vancouver, BC, Canada, ⁵Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada
Background/Purpose: An increased risk of premature atherosclerosis has been well described in patients with rheumatoid arthritis and systemic lupus erythematosus. However, there is limited data…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].