Abstract Number: 780 • 2013 ACR/ARHP Annual Meeting
Serious Infection Rates Among Patients With Systemic Lupus Erythematosus Receiving Corticosteroids and Immunosuppressants
Background/Purpose: Infections are among the leading causes of hospitalization and mortality in patients with systemic lupus erythematosus (SLE); approximately 50% have a serious infection during…Abstract Number: 781 • 2013 ACR/ARHP Annual Meeting
Mortality Rates, Readmissions and Revascularisation Following a First Myocardial Infarction In Patients With Autoimmune Rheumatic Disease Compared With Controls
Background/Purpose: We have previously demonstrated increased case fatality following myocardial infarction (MI) in rheumatoid arthritis (RA) patients[1], however post-MI case fatality has not been investigated…Abstract Number: 782 • 2013 ACR/ARHP Annual Meeting
Rates Of Malignancies In Patients From 5 Rheumatoid Arthritis Registries Across The World
Background/Purpose: The overall incidence of cancer in patients with rheumatoid arthritis (RA) is modestly elevated compared with the general population. The extent to which cancer…Abstract Number: 783 • 2013 ACR/ARHP Annual Meeting
Outcome In Patients With Rheumatoid Disease: Simple Screening Tools Predict Cardiovascular Events and Death
Background/Purpose: Patients with rheumatoid disease (RD) have an increased mortality risk compared to the normal population, mainly due to cardiovascular (CV) disease. Only a proportion…Abstract Number: 784 • 2013 ACR/ARHP Annual Meeting
IgG4+ Plasmablasts Are A Novel Biomarker In IgG4-Related Disease
Background/Purpose: IgG4-related disease (IgG4-RD) is an immune-mediated disorder that responds to B cell depletion with rituximab (RTX). We detected IgG4+ plasmablasts in the sera of…Abstract Number: 785 • 2013 ACR/ARHP Annual Meeting
Ophthalmic Manifestations Of IgG4-Related Disease: A Single-Center Experience
Background/Purpose: IgG4-related disease (IgG4-RD) is an inflammatory disorder responsible for fibrosing, tumefactive lesions that can present in nearly any anatomic location. The orbital manifestations of…Abstract Number: 786 • 2013 ACR/ARHP Annual Meeting
Antibodies Against Drp-4 and Macropain Subunit C2 As a Potential Marker Of Aosd
Background/Purpose: Making the diagnosis of adult-onset Still's disease (AOSD) is mainly based on the exclusion of inflammatory, infectious and malignant diseases. There are no specific…Abstract Number: 787 • 2013 ACR/ARHP Annual Meeting
Serum Leucine-Rich Alpha-2 Glycoprotein As a Marker For Disease Activity In Adult-Onset Still’s Disease
Background/Purpose: Leucine-rich a2-glycoprotein (LRG) is a plasma protein which contains leucine-rich repeats. Though physiological functions of LRG have not been clarified yet, it has been…Abstract Number: 767 • 2013 ACR/ARHP Annual Meeting
Zinc Finger Protein ZCCHC6 Is Highly Expressed In Osteoarthritic Cartilage and Regulate The Expression Of Interleukin-6 In Human Chondrocytes
Background/Purpose: Interleukin-1β (IL-1β) is the major cytokine involved in cartilage catabolism in osteoarthritis(OA) and induces the expression of pro-inflammatory cytokine IL-6. Members of cytoplasmic RNA…Abstract Number: 748 • 2013 ACR/ARHP Annual Meeting
Efficacy Of Methotrexate For Remission Induction and Maintenance In Granulomatosis With Polyangiitis In Routine Clinical Practice
Background/Purpose: Methotrexate has been shown to be effective for both induction (non-severe disease) and maintenance of remission in patients with Granulomatosis with Polyangiitis (GPA) in…Abstract Number: 749 • 2013 ACR/ARHP Annual Meeting
High Clinical Remission Rate With Relatively High Incidence Of Serious Infection In Newly-Onset ANCA-Associated Vasculitides In Japan – A Report From The Nationwide Prospective Cohort Study
Background/Purpose: Clinical characteristics and antineutrophil cytoplasmic antibody (ANCA)-serology of ANCA-associated vasculitis (AAV) patients are substantially different between Western and Asian countries. We investigated effectiveness and…Abstract Number: 750 • 2013 ACR/ARHP Annual Meeting
Maintenance Treatment In Childhood Granulomatosis With Polyangiitis
Background/Purpose: Granulomatosis with Polyangiitis (GPA) is a rare but life threatening disease. Most children present with pulmonary bleeds and/or renal failure. Most treatment regimens are…Abstract Number: 751 • 2013 ACR/ARHP Annual Meeting
Fatigue, Pain, and Functional Disability Among Patients With Vasculitis
Background/Purpose: Vasculitis is a heterogeneous group of diseases often resulting in severe morbidity affecting patients’ quality of life. These morbidities are generally attributed to disease…Abstract Number: 752 • 2013 ACR/ARHP Annual Meeting
Cardiovascular Outcomes Are Worse In Microscopic Polyangiitis Compared To Granulomatosis With Polyangiitis: Data From An Inception Cohort Of Patients With Anti-Neutrophil Cytoplasm Antibody Associated Systemic Vasculitis
Background/Purpose: A greater than three-fold increase in cardiovascular mortality as been reported within the first five years of diagnosis of anti-neutrophil cytoplasmic antibody (ANCA) associated…Abstract Number: 753 • 2013 ACR/ARHP Annual Meeting
Validation Of The New Histopathological Classification Of ANCA Glomerulonephritis and Its Association With Renal Outcomes In a Paediatric Population
Background/Purpose: Anti-Neutrophil Cytoplasmic Antibody (ANCA) associated glomerulonephritides (ANCA GN) include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and Churg-Strauss. A novel histopathologic classification for GPA…