Abstracts Archive - Page 2192 of 2425 - ACR Meeting Abstracts

Abstract Number: 884 • 2013 ACR/ARHP Annual Meeting
Treatment Of Lupus Nephritis With Abatacept Plus Low-Dose Pulse Cyclophosphamide Followed By Azathioprine (the Euro-Lupus Regimen): Twenty-Four Week Data From a Double-Blind Controlled Trial
David Wofsy¹, Anca Askanase², Patricia C. Cagnoli³, W. Winn Chatham⁴, Gabriel Contreras⁵, Maria Dall'era⁶, Mary Anne Dooley⁷, Hilda Fragoso-Loyo⁸, David R. Karp⁹, Meenakshi Jolly¹⁰, Kenneth Kalunian¹¹, Diane L. Kamen¹², Iris Lee¹³, Marc C. Levesque¹⁴, S. Sam Lim¹⁵, Meggan Mackay¹⁶, Cesar Ramos-Remus¹⁷, Brad H. Rovin¹⁸, Tammy O. Utset¹⁹, Swamy Venuturupalli²⁰, Robert Winchester²¹, Linna Ding²², Wendy Gao²², Lynette Keyes-Elstein²³ and Patti Tosta²⁴, ¹Rheumatology/Immunology, University of California San Francisco and NIAID Autoimmunity Centers of Excellence, San Francisco, CA, ²NYU School of Medicine, New York, NY, ³Int Med/Div of Rheum, University of Michigan Health, Ann Arbor, MI, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵University of Miami, Miami, FL, ⁶Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁷University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁸Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ⁹Rheumatic Diseases Division, UT Southwestern Medical Center, Dallas, TX, ¹⁰Rheumatology, Rush University Medical Center, Chicago, IL, ¹¹UCSD School of Medicine, La Jolla, CA, ¹²Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, ¹³Nephrology, Temple University, Philadelphia, PA, ¹⁴Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹⁵Emory University School of Medicine, Division of Rheumatology, Atlanta, GA, ¹⁶Autoimmune & Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, NY, ¹⁷Unidad de Investigacion en Enfermedades Cronico-Degenerativas, Guadalajara, Mexico, ¹⁸Division of Nephrology, Ohio State University Medical Center, Columbus, OH, ¹⁹Rheumatology, University of Chicago Medical Center, Chicago, IL, ²⁰Cedars-Sinai Medical Center, West Hollywood, CA, ²¹Dept of Medicine & Pathology, Columbia University, New York, NY, ²²NIAID, Bethesda, MD, ²³Rho Federal Systems, Inc., Chapel Hill, NC, ²⁴Immune Tolerance Network, San Francisco, CA
Background/Purpose: Studies in murine models for SLE have shown that CTLA4Ig can ameliorate murine lupus nephritis. Moreover, the combination of CTLA4Ig plus intravenous cyclophosphamide (IVC)…
Abstract Number: 885 • 2013 ACR/ARHP Annual Meeting
Fatigue In SLE Is Associated With Upregulation Of Interferon- Alpha Related Gene Transcripts
Maureen A. McMahon¹, Jennifer M. Grossman², Bevra H. Hahn³, Lori Sahakian⁴, Isao Matsuura⁵, Elaine Lourenco⁶ and Brian Skaggs⁶, ¹Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²Division of Rheumatology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, ³Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁴Division of Rheumatology, Department of Medicine,, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁵UCLA David Geffen School of Medicine, Los Angeles, CA, ⁶Medicine/Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Fatigue is a major complaint in at least 80% of SLE patients, and is often listed as the most disabling symptom of the disease;…
Abstract Number: 886 • 2013 ACR/ARHP Annual Meeting
Lupus Neutrophil Extracellular Traps Render High Density Lipoprotein Oxidized and proatherogenic
Carolyne K. Smith¹, Anuradha Vivekanandan-Giri², Jason S. Knight³, Paul Ryan Thompson⁴, Subramaniam Pennathur² and Mariana J. Kaplan⁵, ¹Rheumatology and Graduate Program in Immunology, University of Michigan, Ann Arbor, MI, ²Internal Medicine/Nephrology, University of Michigan Nephrology, Ann Arbor, MI, ³Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, ⁴The Scripps Research Institute, Jupiter, FL, ⁵Systemic Autoimmunity Branch, National Institutes of Health/NIAMS, Bethesda, MD
Background/Purpose: Cardiovascular risk is significantly increased in systemic lupus erythematosus (SLE) patients. This phenomenon cannot be explained by the Framingham risk equation. Previous reports suggest that…
Abstract Number: 887 • 2013 ACR/ARHP Annual Meeting
Atherosclerosis and Cardiovascular Disease In Systemic Lupus Eryhematosus Are Related To An Inflammatory/Oxidative Status Linked To The Autoimmune Condition and The Clinical Activity Of The Disease. Effect Of Statins Treatment
Chary Lopez-Pedrera¹, Patricia Ruiz-Limon¹, Carlos Perez-Sanchez¹, Mª Angeles Aguirre², Nuria Barbarroja¹, Tomás Cerdó-Ráez³, Maria Laura Bertolaccini⁴, Munther A. Khamashta⁵, Antonio Rodriguez-Ariza⁶, Yolanda Almaden⁷, Husam Khraiwesh⁸, Jose Antonio Gonzalez-Reyes⁹, Jose Manuel Villalba¹⁰, Eduardo Collantes¹¹ and Mª Jose Cuadrado¹², ¹Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, ²Rheumatology, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, ³Imibic, Córdoba, Spain, ⁴Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, ⁵Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, ⁶Oncology Service and Research Unit, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, ⁷Imibic, Códoba, Spain, ⁸UCO, Córdoba, Spain, ⁹Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain, ¹⁰Cell Biology, Physiology and Immunology, University of Cordoba, Agrifood Campus of International Excelence (ciA3), Cordoba, Spain, ¹¹Rheumatology, Hospital Reina Sofia, Cordoba, Spain, ¹²Lupus Research Unit, The Rayne Institute, London, United Kingdom
Background/Purpose: Atherosclerosis (AT) and cardiovascular disease (CVD) are enhanced systemic lupus erythematosus (SLE). Although there is evidence that statins have anti-inflammatory properties, their mechanism of…
Abstract Number: 848 • 2013 ACR/ARHP Annual Meeting
Human Papillomavirus Vaccine Uptake Among Children and Young Adults With Autoimmune Diseases
Candace H. Feldman¹, Linda T. Hiraki², Joyce Lii³ and Seoyoung C. Kim⁴, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, ³Department of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ⁴Div. of Pharmacoepidemiology and Pharmacoeconomics, Div. of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Autoimmune diseases such as lupus and inflammatory bowel disease are associated with increased rates of human papillomavirus (HPV), the most common sexually transmitted disease…
Abstract Number: 849 • 2013 ACR/ARHP Annual Meeting
Reasons For Failure To Obtain Influenza and Pneumococcal Vaccines Among Immunosuppressed Individuals With Systemic Lupus Erythematosus
Erica F. Lawson¹, Laura Trupin², Emily von Scheven³, Edward H. Yelin² and Jinoos Yazdany², ¹Pediatrics, University of California, San Francisco, San Francisco, CA, ²Medicine, UC San Francisco, San Francisco, CA, ³Pediatrics, UC San Francisco, San Francisco, CA
Background/Purpose: Infection is the third-leading cause of death in individuals with systemic lupus erythematosus (SLE) in developed countries. Nearly half of those deaths are attributed…
Abstract Number: 850 • 2013 ACR/ARHP Annual Meeting
Salivary Gland Ultrasonography: A Highly Specific Tool For The Early Diagnosis Of Primary Sjögren’s Syndrome
Nicoletta Luciano¹, Chiara Baldini¹, Gaia Tarantini², Rachele Pascale², Francesca Sernissi¹, Linda Carli¹, Francesco Ferro¹, Rosaria Talarico¹, Marta Mosca³, Davide Caramella⁴ and Stefano Bombardieri¹, ¹University of Pisa, Rheumatology Unit, Pisa, Italy, ²Department of Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy, ³Rheumatology Unit, University of Pisa, Pisa, Italy, ⁴University of Pisa, Department of Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy
Background/Purpose: Recently, Cornec D. et al. reported that salivary gland ultrasonography (SGUS) was characterized by a sensitivity of 65.8% and a specificity of 95.3%, in…
Abstract Number: 851 • 2013 ACR/ARHP Annual Meeting
Salivary Gland Ultrasonography Improves The Diagnostic Performance Of ACR 2012 Classification Criteria For Sjögren’s Syndrome, Even In The Early Stages Of The Disease
Divi Cornec¹, Sandrine jousse-Joulin², Thierry Marhadour³, Jacques-Olivier Pers⁴, Yves Renaudineau⁴, Alain Saraux⁵ and Valerie Devauchelle-Pensec⁶, ¹Department of rheumatology, Brest Occidentale University, Brest, France, ²Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ³Rheumatology, CHU de la Cavale Blanche, Brest, France, ⁴Unit of immunology, EA 2216, Brest Occidentale University, Brest, France, ⁵Department of rheumatology and unit of immunology (EA 2216), CHU Brest et Université Bretagne Occidentale, Brest, France, ⁶Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: Recently published ACR classification criteria for primary Sjögren’s syndrome (pSS) include only 3 objective tests: 1) a serological item: anti-SSA/SSB antibodies or [antinuclear antibody…
Abstract Number: 852 • 2013 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosous and Primary Sjogren’s Syndrome May Display Joint Erosions On MRI As Well As Healthy Control, But Cannot Be Considered As Erosive Disease Such As Rheumatoid Arthritis: : An MRI Observational Study Of 90 Subjects
Frédérique Gandjbakhch¹, Violaine Foltz², Jérôme Renoux³, Nahalie Cozic⁴, Nathalie Costedoat-Chalumeau⁵, Damien Sene⁶, Guillaume Mercy⁷, Zahir Amoura⁸, Jean-Charles Piette⁹, Nathalie Morel¹⁰, Pierre Bourgeois¹¹ and Bruno Fautrel¹², ¹Department of Rheumatology, APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, ²APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, ³Radiology, Pitie-Salpetriere Hospital, Paris, France, ⁴APHP, Pitie Salpetriere Hospital, department of statistics, Paris, France, ⁵Internal Medicine, Hopital Cochin, Paris, France, ⁶Internal Medicine, Hopital Lariboisière, Paris, France, ⁷APHP, Pitie-Salpétrière Hospital, paris, France, ⁸Department of Internal Medicine 2. Referal center for SLE/APS, CHU Pitié-Salpêtrière, Paris, France, ⁹Department of Internal Medicine 1., CHU Pitié-Salpêtrière, Paris, France, ¹⁰Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, Paris, France, ¹¹Rheumatology, APHP,Pitie-Salpetriere Hospital, Paris 6, Paris, France, ¹²Paris 6 – Pierre et Marie Curie University; AP-HP, Rheumatology, Pitié-Salpêtrière Hospital, - GRC-UPMC 08 – EEMOIS, Paris, France
Background/Purpose: Recent studies tend to demonstrate presence of MRI erosion in Systemic Lupus Erythematosous (SLE) and primary Sjogren’s syndrome (pSS). The objective of this study…
Abstract Number: 853 • 2013 ACR/ARHP Annual Meeting
Capillaroscopy Compared With Color Doppler Ultrasound Of Digital Arteries For Distinguishing Primary From Secondary Raynaud’s Phenomenon
Wolfgang A. Schmidt¹, Katharina Pagel², Bernd Schicke³ and Andreas Krause⁴, ¹Med Ctr Rheumatology Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, ²Medical Ctr Rheumatol Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, ³Tumorzentrum Berlin, Berlin, Germany, ⁴Immanuel Krankenhaus Berlin, Berlin, Germany
Background/Purpose: Raynaud’s phenomenon (RP) is commonly seen in rheumatology practice. Differentiating primary from secondary RP is important for disease management and prognosis. How does capillaroscopy…
Abstract Number: 854 • 2013 ACR/ARHP Annual Meeting
Aortic Wall Thickness In Patients Without Aortitis: a Computed Tomography-Based Study Of 100 Patients
Afif Nakhleh¹, Irina Rukhkyan², Vladimir Wolfson³, Itzhak A. Rosner⁴, Majed Odeh⁴ and Gleb Slobodin⁵, ¹Internal Medicine, Bnai Zion Medical Center, Haifa, Israel, ²Rehabilition, Bnai Zion Medical Center, Haifa, Israel, ³Radiology, Bnai Zion Medical Center, Haifa, Israel, ⁴Bnai Zion Medical Center, Haifa, Israel, ⁵Rheumatology, Bnai Zion Medical Center, Haifa, Israel
Background/Purpose: Thickening of the aortic wall, probably the earliest CT sign of aortitis, is frequently missed as there are no accepted criteria for normal aortic…
Abstract Number: 855 • 2013 ACR/ARHP Annual Meeting
Ultrasound Evaluation Of The Greater Trochanter Pain Syndrome: Bursitis Or Tendinopathy?
Cristian Quiroz¹, Santiago Ruta², Javier Rosa³, David A. Navarta¹, Ricardo Garcia-Monaco⁴ and Enrique R. Soriano⁵, ¹Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina
Background/Purpose: Greater trochanteric pain syndrome (GTPS) is a common clinical problem that may be caused by a variety of either intra-articular o peri-articular pathologies. Inflammation…
Abstract Number: 856 • 2013 ACR/ARHP Annual Meeting
Cost-Effectiveness Of Urate Lowering Strategies For The Management Of Gout
Eric Jutkowitz¹, Karen Kuntz², Laura T Pizzi³ and Hyon Choi^4,5, ¹Divisions of Health Policy and Management (EJ, KMK), School of Public Health, University of Minnesota, Minneapolis, MN, ²Division of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, MN, ³Thomas Jefferson University, Philadelphia, PA, ⁴Section of Rheumatology and the Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ⁵Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: The new 2012 ACR guidelines for the management of gout have provided updated recommendations; however, the employed method do not address the societal costs…
Abstract Number: 857 • 2013 ACR/ARHP Annual Meeting
Impact of Urate Lowering Therapy On Renal Disease Progression in Patients With Hyperuricemia
Gerald D. Levy¹, T. Craig Cheetham², Nazia Rashid³ and Fang Niu², ¹Int Med/Rheumatology, Southern California Permanente Medical Group, Downey, CA, ²Pharmacy Analytical Services, Kaiser Permanente, Downey, CA, ³Pharmacy Analytical Services, Kaiser Permanente Southern California, Downey, CA
Background/Purpose: The relationship between elevated serum Uric Acid [sUA] and progression of chronic kidney disease is well established.1-3 There are a several small studies on…
Abstract Number: 858 • 2013 ACR/ARHP Annual Meeting
Monosodium Urate Crystal Induced Macrophage Inflammation Is Attenuated By Chondroitin Sulfate: Pre-Clinical Model For Gout Prophylaxis?
Eric W. Orlowsky¹, Thomas V. Stabler², Eulalia Montell³, Josep Verges³ and Virginia B. Kraus², ¹Divsion of Rheumatology, Dept of Internal Medicine, Duke University Medical Center, Durham, NC, ²Medicine/Rheumatology, Duke University Medical Center, Durham, NC, ³Pre-Clinical R&D Area, Pharma Science Division, Bioibérica, Barcelona, Spain
Background/Purpose: Gout is one of the most common forms of inflammatory arthritis and is characterized by acute episodes of joint pain. Monosodium urate (MSU) crystals…

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