ACR Meeting Abstracts

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  • Abstract Number: 1235 • 2013 ACR/ARHP Annual Meeting

    Predictors Of Fracture In Patients With Osteopenia: Data From An Observational Cohort

    Kathryn Mitchell1, Peter Diggle1 and Marwan Bukhari1,2, 1Faculty of Health and Medicine, Lancaster, United Kingdom, 2Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom

    Background/Purpose: The risk factors for osteoporotic fragility fractures are well documented in the literature and although they are associated with a diagnosis of established osteoporosis…
  • Abstract Number: 1236 • 2013 ACR/ARHP Annual Meeting

    Outcomes and Costs Of Sacral Insufficiency Fractures

    Shahryar Hadavi1, Sanam Kia1, Christian Dejaco2, Bhaskar Dasgupta2 and Frances Borg3, 1Rheumatology Department, Southend University Hospital, Westcliff-on-Sea, United Kingdom, 2Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom, 3Rheumatology, Southend University Hospital, Westcliff-on-sea, United Kingdom

    Background/Purpose: Sacral insufficiency fracture (SIF) is a poorly recognised cause of lower back pain in the elderly with significant potential morbidity. Diagnosis is often slow…
  • Abstract Number: 1237 • 2013 ACR/ARHP Annual Meeting

    Denosumab Leads To Significantly Greater Increases In Bone Mineral Density Than Ibandronate and Risedronate In Postmenopausal Women At High Risk For Fracture Who Were Previously Treated With An Oral Bisphosphonate

    Jacques P. Brown1, Michael A. Bolognese2, Pei-Ran Ho3, Jesse Hall3, Christian Roux4, Henry G. Bone5, Sydney Bonnick6, Joop van den Bergh7, Irene Ferreira8, Prayashi Ghelani9, Paula Dakin3, Rachel B. Wagman3 and Chris Recknor10, 1CHU de Québec Research Centre and Laval University, Quebec City, QC, Canada, 2Bethesda Health Research Center, Bethesda, MD, 3Amgen Inc., Thousand Oaks, CA, 4Paris Descartes University, Paris, France, 5Michigan Bone and Mineral Clinic, Detroit, MI, 6Clinical Research Center of North Texas, Denton, TX, 7VieCuri Medical Centre and Maastricht University, Venlo, Netherlands, 8Amgen Inc., Cambridge, United Kingdom, 9Ovatech Solutions, London, United Kingdom, 10United Osteoporosis Centers, Gainesville, GA

    Denosumab Leads to Significantly Greater Increases in Bone Mineral Density Than Ibandronate and Risedronate in Postmenopausal Women at High Risk for Fracture Who Were Previously…
  • Abstract Number: 1238 • 2013 ACR/ARHP Annual Meeting

    Persistence At 12 Months With Denosumab (Prolia®) In Postmenopausal Women With Osteoporosis: Interim Results From a Prospective Observational Study

    Stuart L. Silverman1, Ethel Siris2, David L. Kendler3, Dea Belazi4, Jacques P. Brown5, Deborah T. Gold6, E. Michael Lewiecki7,8, Alexandra Papaioannou9, Christine Simonelli10, Irene Ferreira11, Paula Dakin12, Suresh Siddhanti12, Bradley Stolshek12 and Christopher Recknor13, 1Cedars-Sinai Medical Center, UCLA Center of Excellence, Los Angeles, CA, 2Columbia University, New York, NY, 3University of British Columbia, Vancouver, BC, Canada, 4AlchemiPharma LLC, Wayne, PA, 5CHU de Québec Research Centre and Laval University, Quebec City, QC, Canada, 6Duke University Medical Center, Durham, NC, 7University of New Mexico School of Medicine, Albuquerque, NM, 8New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, 9Geriatric Medicine, McMaster University, Hamilton, ON, Canada, 10Health East Osteoporosis Care, Woodbury, MN, 11Amgen Inc., Cambridge, United Kingdom, 12Amgen Inc., Thousand Oaks, CA, 13United Osteoporosis Centers, Gainesville, GA

    Background/Purpose: Persistence with osteoporosis therapy is important for optimal reduction of fracture risk. Persistence with denosumab was >90% in a randomized clinical trial in women…
  • Abstract Number: 1239 • 2013 ACR/ARHP Annual Meeting

    The Effects Of Hyperparathyroidism On Body Mass Index and Bone Mineral Density- An Observational Case-Control Study

    Chris Varley1, Alexander Oldroyd2 and Marwan Bukhari3, 1Lancaster Medical School, Lancaster University, Llandudno, United Kingdom, 2Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, 3Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom

    Background/Purpose: Hyperparathyroidism is associated with reduced bone mineral density (BMD) and increased fracture risk. A previous study from this group has shown that bone loss…
  • Abstract Number: 1240 • 2013 ACR/ARHP Annual Meeting

    Study On The Relationship Between The Preoperative Stay and Morbimortality In Patients With Hip Fracture

    Irene Martin1, Maria Aparicio1, Laura López-Vives1, Montserrat Jordana1, Antoni Coscujuela2, Abelardo Montero3 and Carmen gomez-Vaquero1, 1Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, 2Orthopedic Surgery Services., Hospital Universitari de Bellvitge, Barcelona, Spain, 3Internal Medicine, Hospital Universitari de Bellvitge, Barcelona, Spain

    Background/Purpose: Introduction: The preoperative stay (PS) in patients with hip fracture has been classically associated with the resultant morbimortality of the process. As a consequence,…
  • Abstract Number: 1241 • 2013 ACR/ARHP Annual Meeting

    A Low Serum 25(OH) Vitamin D Level As a Risk Factor For Incidence and Severity Of Vertebral Fracture In Glucocorticoid-Induced Osteoporosis In Japan

    Mari Ushikubo1, Harumi Kuda1, Sayaka Kubo1, Keisuke Izumi2, Kumiko Akiya1 and Hisaji Oshima1, 1Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, 2Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: Although levels of serum 25(OH) vitamin D (25(OH)D) have been discussed for preventing osteoporotic fractures in primary osteoporosis, an importance of the levels has…
  • Abstract Number: 1242 • 2013 ACR/ARHP Annual Meeting

    A Prospective Randomized Open Label Trial To Evaluate The Effect Of Food On Vitamin D Absorption

    Lucas Grisanti1, Zeenat Ali2, Joseph M. Grisanti3, James Hatem4, Mary Brennan5, Michael Grisanti3, Mary Margaret O'Neil3, Linda Burns3 and Kostas Botsoglou6, 1Department of Biology, College of Wooster, Wooster, OH, 2Medicine, Mercy Hospital of Buffalo, Buffalo, NY, 3Buffalo Rheumatology, Orchard Park, NY, 4BioStatistics, Buffalo Rheumatology, Orchard Park, NY, 5Research Division, Buffalo Rheumatology, Orchard Park, NY, 6Sisters Hospital, Buffalo, NY

    Background/Purpose: Vitamin D deficiency is commonplace throughout the world and is associated with a number of health related consequences. Being a fat-soluble vitamin, speculation has…
  • Abstract Number: 1243 • 2013 ACR/ARHP Annual Meeting

    Osteoporosis Medication Adherence: Reasons For Stopping and Not Starting

    Amy H. Warriner1, Ryan C. Outman2, Allison Wyman3, Fred H. Hooven4, Jonathan D. Adachi5, Roland Chapurlat6, Juliet E. Compston7, Cyrus Cooper8, Jeffrey R. Curtis9, Adolfo Díez-Pérez10, Robert Lindsay11, Lyn March12, Jeri W. Nieves11 and Kenneth G. Saag13, 1Endocrinology, Diabetes, and Metabolism, The University of Alabama at Birmingham, Birmingham, AL, 2Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, 3Center for Outcomes Research, Center for Outcomes Research, UMass Medical School, Worcester, MA, 4University of Massachusetts, Worcester, MA, 5McMaster University, Hamilton, ON, Canada, 6Service de Rhumatologie et Pathologie Osseuse, INSERM UMR 1033 and Université de Lyon, Hôpital Edouard Herriot, Lyon, France, 7University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, 8MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom, 9Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 10Internal Medicine, Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Barcelona; and RETICEF, ISCIII Madrid; Spain, Barcelona, Spain, 11Helen Hayes, West Haverstraw, NY, 12Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 13Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Medication adherence with prescription osteoporosis medications is poor, with approximately half remaining adherent in the first year of treatment. Moreover, approximately one-third who are…
  • Abstract Number: 1245 • 2013 ACR/ARHP Annual Meeting

    The Differential Effect Of Smoking On Bone Mineral Density At The Lumbar Spine and Neck Of Femur In Each Gender: An Observational Study

    William Hedges1, Alexander Oldroyd2 and Marwan Bukhari3, 1Foundation Programme, Royal Lancaster Infirmary, University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, United Kingdom, 2Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, 3Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom

    Background/Purpose: Current smoking is a known risk factor for loss of bone mineral density (BMD), and is part of the FRAX ™ 10-year fracture risk…
  • Abstract Number: 1246 • 2013 ACR/ARHP Annual Meeting

    Efficacy Of a 6-Month Treatment With Strontium Ranelate 2g/Day In The Improvement Of Long Bone Fractures With Delayed-Union Or Non-Union

    Jean-Marc Feron1, Vaclav Vyskocil2, Carlina Albanese3, Luis Augusto Tavares Russo4 and Jean-Denis Laredo5, 1Service de chirurgie orthopédique et traumatologique, Hôpital Saint Antoine, GHU Est , AP-HP, Paris, France, 2Osteocentrum, 3. interní klinika, Všeobecná fakultní nemocnice, U Nemocnice 1, Praha2, Czech Republic, 3Dipartimento di scienze radiologiche, Università degli studi, ROMA, Italy, 4CCBR Brasil, Rua Mena Barreto, 33 Botofogo, 22271, Rio de Janeiro, Brazil, 5Service Radiologie Ostéo-Articulaire, Hopital Lariboisière, 2, rue Ambroise Paré, 75475, Paris, France

    Background/Purpose: To assess the efficacy of strontium ranelate 2g/day in the improvement of healing of peripheral fractures with delayed union or aseptic non-union. Methods: International,…
  • Abstract Number: 1247 • 2013 ACR/ARHP Annual Meeting

    Association Between Bisphosphonate Switching Behavior and Cost Outcomes In Postmenopausal United States Veterans

    Joanne Lafleur1, Scott L. DuVall2, Jeffrey R. Curtis3, Robert A Adler4, Tina Willson5, Irene Agodoa6, Bradley Stolshek7 and Richard E. Nelson8, 1University of Utah College of Pharmacy, Salt Lake City, UT, 2VA Salt Lake City Health Care System and University of Utah School of Medicine, Salt Lake City, UT, 3University of Alabama at Birmingham, Birmingham, AL, 4Internal Medicine, Hunter Holmes McGuire VA Medical Center, Richmond, VA, 5Pharmacotherapy, University of Utah, Salt Lake City, UT, 6Amgen Inc, Thousand Oaks, CA, 7Amgen, Inc., Thousand Oaks, CA, 8Division of Epidemiology, Salt Lake City VA and University of Utah, Salt Lake City, UT

    Background/Purpose: Many bisphosphonate-treated patients discontinue therapy within the first year. Some later restart the same or a different bisphosphonate. The implications of this on total…
  • Abstract Number: 1248 • 2013 ACR/ARHP Annual Meeting

    Prevalence Of Vitamin D Inadequacy In European Postmenopausal Women Aged Over 80 Years

    Olivier Bruyere1, Justine Slomian1, Charlotte Beaudart2, Fanny Buckinx3, Etienne Cavalier4, Sophie Gillain5, Jean Petermans5 and Jean-Yves Reginster1, 1Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, 2Public Health/Epidemiology, University of Liège, Liège, Belgium, 3Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, 4Department of Clinical Chemistry, CHU de Liege, Liege, Belgium, 5Geriatric Department, CHU de Liege, Liege, Belgium

    Background/Purpose: Inadequate vitamin D level is associated with secondary hyperparathyroidism and increased bone turnover and bone loss, which in turn increases fracture risk. The objective…
  • Abstract Number: 1249 • 2013 ACR/ARHP Annual Meeting

    Contrasting Pathophysiology and Behavioural Responses Associated With Osteoarthritis and An Inflammatory Arthropathy

    Sanaa Zaki1, Margaret M. Smith2, Susan Smith1, Mark Connor3 and Christopher B. Little2, 1Raymond Purves Bone and Joint Research Laboratories, University of Sydney, St Leonards, Australia, 2Raymond Purves Bone and Joint Research Labs, University of Sydney, St Leonards, Australia, 3Australian School of Advanced Medicine, Macquarie University, North Ryde, Australia

    Background/Purpose: Osteoarthritis (OA) affects more than 15% of the population, and is the major cause of disability in people over 60. There are no therapies…
  • Abstract Number: 1250 • 2013 ACR/ARHP Annual Meeting

    Serological Markers Of Structural Integrity and Inflammation Is Associated With Pain In Osteoarthritis

    Anne Sofie Siebuhr1, Lars Arendt-Nielsen2, Thomas Navndrup Eskehave3, Morten Asser Karsdal4, Kristian Kjaer Petersen5, Ole Simonsen6 and Anne C. Bay-Jensen7, 1Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, 2Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Center for Sensory-Motor Interaction, Aalborg, Denmark, 3Center for Clinical and Basic Research and C4Pain, Aalborg, Denmark, 4Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, 5Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Denmark, Center for Sensory-Motor Interaction, Aalborg, Denmark, 6Frederikshavn Hospital, Frederikshavn, Denmark, 7Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark

    Background/Purpose: Pain is associated with diagnosed osteoarthritis (OA), but little clinically association is found between joint integrity and the pain the individual patient experience. Peripheral…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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