ACR Meeting Abstracts

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  • Abstract Number: 1357 • 2013 ACR/ARHP Annual Meeting

    Coping Style Is An Independent Predictor For Disease Activity At Three Months In Early Arthritis Patients Initiating Therapy With Disease Modifying Anti-Rheumatic Drugs

    T. Martijn Kuijper1, Hong Xiong2, A.E.a.M. Weel3, A.H. Gerards4, Jendé van Zeben5, P.H.P. de Jong6, Ilja Tchetverikov7, P.B.J. de Sonnaville8, M.V. Krugten9, B.A. Grillet10, Jolanda J. Luime2 and Johanna M.W. Hazes11, 1Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, 2Rheumatology, Erasmus Medical Center, Rotterdam, Netherlands, 3Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 4Department of Rheumatology, Vlietland Hospital, Schiedam, Netherlands, 5Rheumatology, Sint Franciscus Gasthuis, Rotterdam, Netherlands, 6Department of Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, 7Albert Schweitzer Ziekenhuis, Dordrecht, Netherlands, 8Rheumatology, Admiraal de Ruyter Ziekenhuis, Goes, Netherlands, 9Department of Rheumatology, Admiraal de Ruyter Hospital, Vlissingen, Netherlands, 10Department of Rheumatology, Zorgsaam Hospital, Terneuzen, Netherlands, 11Rheumatology, Erasmus MC, Rotterdam, Netherlands

    Background/Purpose: To explore the effect of psychosocial factors on the Disease Activity Score (DAS) and its components in early arthritis patients three months after initiating…
  • Abstract Number: 1358 • 2013 ACR/ARHP Annual Meeting

    No Differences In Patient-Reported Outcomes By Methotrexate Dose Among Early Rheumatoid Arthritis Patients Treated Concomitantly With Adalimumab: Results From The Concerto Trial

    Roy Fleischmann1, Alan Kivitz2, Ronald F van Vollenhoven3, James W. Shaw4, Stefan Florentinus5, Piyalal M. Karunaratne4, Hartmut Kupper6, Maxime Dougados7 and Gerd Burmester8, 1University of Texas Southwestern Medical Center, Dallas, TX, 2Altoona Center for Clinical Research, Duncansville, PA, 3ClinTRID, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 4AbbVie Inc., North Chicago, IL, 5AbbVie, Rungis, France, 6AbbVie Deutschland GmBH & Co. KG, Ludwigshafen, Germany, 7Hopital Cochin, René Descartes University, Paris, France, 8Department of Rheumatology & Clinical Immunology, Charité-Universitätsmedizin Berlin, Free University and Humboldt University of Berlin, Berlin, Germany

    Background/Purpose: Methotrexate (MTX) in combination with the tumor necrosis factor inhibitor adalimumab (ADA) is an effective therapy for treating rheumatoid arthritis (RA), but the minimum…
  • Abstract Number: 1359 • 2013 ACR/ARHP Annual Meeting

    Does Rheumatoid Arthritis Disease Activity Correlate With Weather Conditions?

    Eimear Savage1, David McCormick1, Stephen McDonald1, Michael Stevenson2, Owen Moore3 and Andrew Cairns4, 1Rheumatology, Belfast Hospitals Trust, Musgrave Park Hospital, Belfast BT9 7JB, Northern Ireland, 2Medical Statistics, Centre for Public Health., Queens University, Belfast. School of Medicine, Dentistry and Biomedical Sciences., Belfast BT12 6BJ, Northern Ireland, 3Rheumatology, St. Vincent’s Hospital, Melbourne, Australia, 4Rheumatology, Belfast Hospitals Trust, Musgrave Park Hospital, Belfast, United Kingdom

    Background/Purpose: Rheumatoid Arthritis is a common inflammatory joint condition affecting up to 1% of the Northern Ireland population.  Patients often report increasing joint pain with…
  • Abstract Number: 1360 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of Biomarkers Involved In Periondontal Disease Including Porphyromonas Gingivalis Antibodies To Predict Response To Infliximab In Rheumatoid Arthritis Patients

    Mélanie Rinaudo-Gaujous1, Pierre Miossec2, Vincent Blasco-Baque3, Philippe Gaudin4, Christian Genin1, Thierry Thomas5, Stéphane Paul1 and Hubert Marotte6, 1Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, 2Department of Clinical Immunology and Rheumatology, Immunogenomics and inflammation research unit, Lyon, France, 3Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, 4Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, 5INSERM U1059 and University Hospital, Saint-Etienne, France, 6LBTO INSERM U1059 University Jean Monnet, Saint-Etienne, France

    Background/Purpose: This study evaluates biological markers of rheumatoid arthritis (RA) severity including matrix metalloproteinase 3 (MMP-3) and Porphyromonas gingivalis (P. gingivalis) serology during infliximab therapy…
  • Abstract Number: 1361 • 2013 ACR/ARHP Annual Meeting

    Stringent Therapies Improve Clinical, Radiographic and Magnetic Resonance Imaging Outcome In Early-Stage Rheumatoid Arthritis Patients From Japanese Population: Longitudinal Study From Nagasaki Early Arthritis Cohort

    Mami Tamai1,2, Yoshikazu Nakashima3, Junko Kita4, Ayuko Takatani4, Ayako Nishino3, Takahisa Suzuki3, Yoshiro Horai3, Akitomo Okada5, Shin-ya Kawashiri3,6, Naoki Iwamoto3, Kunihiro Ichinose3, Kazuhiko Arima6, Hideki Nakamura3, Tomoki Origuchi7, Masataka Uetani8, Katsumi Eguchi9 and Atsushi Kawakami3, 1Center for Health & Community Medicine, Nagasaki University, Nagasaki, Japan, 2Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 3Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 4Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 5Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, 6Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 7Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 8Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 9Sasebo City General Hospital, Sasebo, Nagasaki, Japan

    Background/Purpose: Prognosis of the patients with rheumatoid arthritis (RA) nowadays is supposed to become better by treat-to-target (T2T) strategy. Osteitis determined by magnetic resonance imaging…
  • Abstract Number: 1362 • 2013 ACR/ARHP Annual Meeting

    Isymind Significantly Reduces MTX-Induced Nausea In a Pilot Trial

    Eva Ostermeier1, Hans Ulrich Koetter2, Hans-Peter Tony3 and Ruth Pfister2, 1Rheumatology, University of Würzburg, Würzburg, Germany, 2iSyMind Institut, Giessen, Germany, 3Rheumatology/Clinical Immunology, University of Würzburg, Würzburg, Germany

    Background/Purpose:  MTX is the standard DMARD for treating rheumatoid arthritis and the most important partner for biological DMARDs. However MTX often induces heavy nausea accompanied…
  • Abstract Number: 1363 • 2013 ACR/ARHP Annual Meeting

    Active Tuberculosis Risk With Tumor Necrosis Factor Inhibitors After Treating Latent Tuberculosis -a 7-Year Retrospective Observational Study

    Minkyung Kwon1, Mindong Sung1, Yong-Jin Kwon1, Young Goo Song1, Sang-Won Lee2, Min-Chan Park1, Yong-Beom Park1, Soo-Kon Lee1 and Jason Jungsik Song1, 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, 2Department of Internal Medicine, Yonsei University College of Medicine, Seoul, NV, South Korea

    Background/Purpose: Active tuberculosis (TB) risk increases during anti-tumor necrosis factor (TNF) therapy and latent TB infection (LTBI) screening is recommended in potential TNF inhibitor users.…
  • Abstract Number: 1364 • 2013 ACR/ARHP Annual Meeting

    Detection of Latent Tuberculosis Infection in Rheumatologic Diseases Before Anti-TNFα Therapy: Tuberculin Skin Test Versus IFN-γ Assay

    Suleyman Ozbek1, Ismail Hanta2, Sedat Kuleci3, Gulsah Seydaoglu3 and Ezgi Ozyilmaz3, 1Division of Rheumatology, Cukurova University Faculty of Medicine, Adana, Turkey, 2Pulmonary, Cukurova University, Adana, Turkey, 3Cukurova University, Adana, Turkey

    Background/Purpose: We aimed to evaluate tuberculin skin test (TST) and interferon-gamma (IFN-γ) test results for latent tuberculosis infection (LTBI) in patients with rheumatologic diseases prior…
  • Abstract Number: 1365 • 2013 ACR/ARHP Annual Meeting

    Incidence Of Hepatitis B Virus Reactivation In Patients With Rheumatoid Arthritis During Treatment With Biologics

    Jun Nakamura1, Takao Nagashima1, Katsuya Nagatani2, Taku Yoshio3, Masahiro Iwamoto4 and Seiji Minota5, 1Rheumatology and Clinical Immunology, Jichi Medical University, Tochigi, Japan, 2Division of Rheumatology and Clinical Immunology, Jichi Medical University, Tochigi, Japan, 3Division of Rheumatology and Clinical Immunology, Jichi Medical University, School of Medicine, Shimotsuke-shi, Tochigi-ken, Japan, 4Division of Rheumatology and Clinical Immunology, Jichi Medical University, Shimotsuke, Tochigi, Japan, 5The Safety Evaluation Committee of Actemra® for JIA, Tokyo, Japan

    Background/Purpose: Reactivation of hepatitis B virus (HBV) is very problematic in patients who are receiving biologics. Optimal precaution and management for those patients are still…
  • Abstract Number: 1366 • 2013 ACR/ARHP Annual Meeting

    Abdominal Adiposity and Body Composition In Rheumatoid Arthritis: Relation With Disease Characteristics In A Case-Control Study

    Ivan Ferraz-Amaro1, Esmeralda Delgado-Frías2, Vanesa Hernandez-Hernandez3, Jose Ramon Muñiz4, Antonieta Gonzalez-Diaz5, Angeles Gomez Rodriguez-Bethencourt5 and Federico Diaz-Gonzalez6, 1Rheumatology, Servicio de Reumatologia. Hospital Universitario de Canarias, Tenerife, Spain, 2Rheumatology, Hospital Universitario de Canarias, La Laguna, Spain, 3Rheumatology, Rheumatology Service, Santa Cruz de Tenerife, Spain, 4Resonancia Magnética IMETISA, Resonancia Magnetica IMETISA, Santa Cruz de Tenerife, Spain, 5Servicio de Medicina Nuclear, Santa Cruz de Tenerife, Spain, 6University of La Laguna, Hospital Universitario de Canarias, La Laguna, Spain

    Background/Purpose: To determine the relationship between measures of body composition (total body composition derived from dual energy X-ray absorptiometry and abdominal adiposity through magnetic resonance…
  • Abstract Number: 1367 • 2013 ACR/ARHP Annual Meeting

    Performance Of a Two-Step Latent Tuberculosis Screening Algorithm In Patients With Rheumatoid Arthritis, Psoriatic Arthritis Or Ankylosing Spondylitis Prior To Treatment With Tumor Necrosis Alpha Inhibitors: Prospective Observational Data From The Biorx.Si Registry

    ŽIga Rotar1 and Matija Tomsic2, 1Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 2Department of Rheumatology, University Medical Centre Ljubjana, Ljubljana, Slovenia

    Background/Purpose: Reactivation of latent tuberculosis infection (LTBI) is of concern in patients treated with TNFi. Conversely, TB chemoprophylaxis (CP) is time consuming, delays the initiation…
  • Abstract Number: 1368 • 2013 ACR/ARHP Annual Meeting

    The Effect Of Vitamin D On Early Rheumatoid Arthritis: A Retrospective Cohort Analysis

    Faye A H Cooles1, Arthur G Pratt2,3,4, Wan-Fai Ng3,5, Terry J Aspray3 and John D Isaacs2, 1Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom, 2Institute of Cellular Medicine (Musculoskeletal Research Group), NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, 3Musculoskeletal Directorate, The Freeman Hospital, Newcastle upon Tyne, United Kingdom, 4Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, 5Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle upon Tyne, United Kingdom

    Background/Purpose: There is increasing evidence that vitamin D has immunoregulatory properties in autoimmunity. In established rheumatoid arthritis (RA) there appears to be an inverse association…
  • Abstract Number: 1369 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of Porphyromona Gingivalis Serology In Rheumatoid Arthritis and Non-Rheumatoid Inflammatory Disease

    Mélanie Rinaudo-Gaujous1, Adeline Moreau1, Vincent Blasco-Baque2, Xavier Roblin3, Christian Genin1, Thierry Thomas4, Stéphane Paul1 and Hubert Marotte5, 1Laboratory of Immunology and immunomonitoring, CIC CIE3 Inserm Vaccinology, GIMAP EA3064, Hôpital Nord, Saint-Etienne, France, 2Institute of Cardiovascular and Metabolic Diseases, CHU Rangueil, Toulouse, France, 3Department of gastroenterology, Hôpital Nord, Saint-Etienne, France, 4INSERM U1059 and University Hospital, Saint-Etienne, France, 5INSERM U1059 and University Hospital, Hôpital Nord, Saint-Etienne, France

    Background/Purpose: Periodontal disease (PD) is associated mainly with rheumatoid arthritis (RA), but recent data suggest an association with ankylosing spondylitis (AS). Role of Porphyromonas gingivalis…
  • Abstract Number: 1370 • 2013 ACR/ARHP Annual Meeting

    Prednisone Is a Risk Factor For Pneumocystis Jirovecii Pneumonia In Patients With Rheumatic Diseases: A Case-Control Study With 36 Cases

    Wieneke van den Hombergh1, Annelies van Ede2, J. Fransen3, Femke BG lamers-Karnebeek3, Saskia Kuipers4 and Matthijs Janssen5, 1Rheumatology, UMC st. Radboud, Nijmegen, Netherlands, 2Rheumatology, UMC st Radboud, Nijmegen, Netherlands, 3Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 4Microbiology, UMC st Radboud, Nijmegen, Netherlands, 5Department of Rheumatology, Rijnstate Hospital, Arnhem, Netherlands

     Background/Purpose: Pneumocystis jirovecii is a fungal pathogen that causes pneumonia in immunocompromized hosts. Prednisone is frequently suggested as a risk factor for developing pneumocystis pneumonia (PCP) in patients with rheumatic diseases. If prednisone…
  • Abstract Number: 1371 • 2013 ACR/ARHP Annual Meeting

    Tuberculosis Infection In Patients With Tumor Necrosis Factor–α Antagonists In South Korea;retrospective Analysis Using By National Health Insurance Review and Assessment Service

    Jong Wook Beom1, Eun-Jung Park2, Jinseok Kim3, Se Chang Park4 and Gi Hyeon Seo5, 1Medicine, Jeju National University Hospital, Jeju, South Korea, 2Internal Medicine, Department of Medicine, Jeju National University Hospital, Jeju University School of Medicine, Republic of Korea, Jeju, South Korea, 3Internal Medicine, Jeju National University Hospital, Jeju, South Korea, 4Veterinary Medicine, Seoul National University, Seoul, South Korea, 5Health Insurance Review and Assessment Service, Seoul, South Korea

    Background/Purpose: Tumor necrosis factor-α (TNF-α) antagonists bring new hope for treating rheumatoid arthritis (RA) over the past decade. However, the subsequent increased risk of developing…
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