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  • Abstract Number: 1983 • 2013 ACR/ARHP Annual Meeting

    Prevalence Of Birefringent Crystals In Three Inflammation-Prone Tissues

    Jane Park1, Divya Soman2, Martine P. Roudier3 and Peter A. Simkin4, 1Rheumatology, University of Washington, Seattle, WA, 2University of Washington, Seattle, WA, 3Pathology, University of Washington, Seattle, WA, 4Div of Rheumatology, University of Washington, Seattle, WA

    Background/Purpose: When serum is hyperuricemic, so too are all interstitial fluids other than CSF and sweat.  Anecdotally, urate crystals deposit as grossly visible tophi in…
  • Abstract Number: 1984 • 2013 ACR/ARHP Annual Meeting

    Impact Of Educational Attainment On Health-Related Quality Of Life and Healthcare Utilization Among Veterans With Gout

    Cleopatra Aquino-Beaton1, Jay E. Persselin2, Ari Weinreb1, Meika A Fang1, Jasvinder A. Singh3,4, Erin Duffy5, David Elashoff6, Puja Khanna7,8 and Dinesh Khanna9, 1Rheumatology, VA Greater Los Angeles Healthcare System, Los Angeles, CA, 2Medicine W-111J Div of Rheum, VA Greater Los Angeles Healthcare System, Los Angeles, CA, 3Department of Medicine, University of Alabama, Tuscaloosa, AL, 4Rheumatology, Birmingham VA, Birmingham, AL, 5Medicine, University of California Los Angeles, Los Angeles, CA, 6Medicine- Statistic Core, UCLA Department of Medicine Statistics Core, Los Angeles, CA, 7Division of Rheumatology/Dept. of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, 8Rheumatology, Ann Arbor VA, Ann Arbor, MI, 9Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI

    Background/Purpose: Gout is a debilitating, chronic disease that requires ongoing treatment and effective self-management. Successful gout treatment depends on multiple factors, including educational attainment. Adequate…
  • Abstract Number: 1985 • 2013 ACR/ARHP Annual Meeting

    Prescription Patterns Of Colchicine Before and After Food and Drug Administration Approval

    Eswar Krishnan1, Jasvinder A. Singh2 and Linjun Chen1, 1Medicine, Stanford University, Palo Alto, CA, 2Department of Medicine, University of Alabama, Tuscaloosa, AL

    Background/Purpose: Colchicine, a commonly used drug, had never been subjected to rigorous safety and efficacy studies prior to 2009, when under Hatch-Waxman ACT (1984) and…
  • Abstract Number: 1986 • 2013 ACR/ARHP Annual Meeting

    Colchicine Use and The Risk Of Myocardial Infarction Among Gout Patients: Results From a Community-Based, Informatics-Driven Retrospective Cohort Study

    Daria B. Crittenden1, Binita Shah2, Steven P. Sedlis2, Christopher J. Swearingen3, Eric S. Wagner4, Yvette M. Henry4, Peter B. Berger4, Bruce N. Cronstein1 and Michael H. Pillinger5, 1Internal Medicine, NYU School of Medicine, Division of Rheumatology, New York, NY, 2NYU School of Medicine, Division of Cardiology, New York, NY, 3Pediatric Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, 4Geisinger Health System, Cardiovascular Center for Clinical Research, Danville, PA, 5NYU School of Medicine, Division of Rheumatology, New York, NY

    Background/Purpose: Gout patients have an increased risk of myocardial infarction (MI). Since atherosclerosis and plaque rupture are inflammatory processes, anti-inflammatory gout medications might also reduce…
  • Abstract Number: 1987 • 2013 ACR/ARHP Annual Meeting

    LIVER Outcomes In Gout Patients Treated With Febuxostat and Altered LIVER Function TESTS

    Fernando Perez-Ruiz1,2 and Ana M. Herrero-Beites2,3, 1Servicio de Reumatologia, Hospital Universitario Cruces, Baracaldo, Spain, 2BioCruces Health Research Institute, Baracaldo, Spain, 3Physical Medicine Division, Hospital de Gorliz, Gorliz, Spain

    LIVER OUTCOMES IN GOUT PATIENTS TREATED WITH FEBUXOSTAT AND ALTERED LIVER FUNCTION TESTSBackground/Purpose: patients with significantly altered liver function test (LFTs) at screening do not…
  • Abstract Number: 1988 • 2013 ACR/ARHP Annual Meeting

    Self-Reported Gout, Comorbidities and Healthcare Resource Utilization Data From The 2012 United States National Health and Wellness Survey

    Jasvinder A. Singh1, Kathy Annunziata2 and Puja Khanna3, 1Department of Medicine, University of Alabama, Tuscaloosa, AL, 2Kantar Health, Princeton, NJ, 3Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI

    Background/Purpose: Hyperuricemia and gout are associated with major cardiovascular and metabolic comorbidities. Recently published data on comorbidities and gout epidemiology in the US have been…
  • Abstract Number: 1958 • 2013 ACR/ARHP Annual Meeting

    Does Evaluation Of Hand Bone Loss By Digital x-Ray Radiogrammetry Within The First 3 Months After Diagnosis Of Rheumatoid Arthrits Identify Patients At Risk For Radiological Progression?

    Ewa H. Berglin1 and Solbritt M. Rantapaa-Dahlqvist2, 1Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, 2Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, Umea, Sweden

    Background/Purpose: To evaluate the usefulness of assement of hand bone loss in prediction of radiological progression in patients with early rheumatoid arthritis (RA). Methods: Patients…
  • Abstract Number: 1949 • 2013 ACR/ARHP Annual Meeting

    Assessment Of Wrist Joint Inflammation In Patients With Rheumatoid Arthritis By Quantitative Two- and Three-Dimensional Power Doppler Ultrasonography

    Hsin-Hua Chen, Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; nstitute of Public Health and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan

    Background/Purpose: To assess the intra-operator and inter-operator reliability of two-dimensional (2D) and three-dimensional (3D)-power Doppler ultrasonography (PDUS) computer-aided quantification data for wrist joint vascularity.Methods: This…
  • Abstract Number: 1950 • 2013 ACR/ARHP Annual Meeting

    Relationship Between Radiographic Joint Space Narrowing, Sonographic Cartilage Thickness and Anatomy In Rheumatoid Arthritis and Control Joints

    Peter Mandl1, Gabriela Supp2, Gabor Baksa3, Daniel Aletaha4, Reka Kurucz5, Dora Niedermayer6, Helga Radner7, Paul Studenic8, Peter V. Balint9 and Josef S. Smolen10, 1Medical University of Vienna, Vienna, Austria, 2Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Semmelweis University, Budapest, Hungary, 4Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 5National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 6PsAID taskforce, EULAR, Zurich, Switzerland, 7Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria, 8Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 9Rheumatology, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 10Medical University of Vienna and Hietzing Hospital, Vienna, Austria

    Background/Purpose: To validate ultrasound (US) for measuring cartilage thickness, by evaluating cartilage thickness on cadaver specimens of metacarpophalangeal (MCP) joints by US and conventional measurement.…
  • Abstract Number: 1951 • 2013 ACR/ARHP Annual Meeting

    The Spring Ligament Window: A Unique Sonoanatomic View Into a Complex Rheumatoid Joint

    Joanne Kitchen1, I. Moller2, Maribel Miguel-Perez3 and David A. Bong4, 1Instituto Poal de Reumatolgia, Barcelona, Spain, 2Instituto Poal, Barcelona, Spain, 3University of Barcelona, Barcelona, Spain, 4Instituto Poal de Reumatologia, Barcelona, Spain

    Background/Purpose: The calcaneonavicular or spring ligament (SL) is a group of 3 stout non-elastic fibrocartilaginous bands in the medial mid-foot that is important in maintaining…
  • Abstract Number: 1952 • 2013 ACR/ARHP Annual Meeting

    The Value Of An Automated Ultrasound System In The Detection Of Synovitis

    Ruediger Mueller1, Mathias Gruenke2, Joerg Wendler3, Florian Schuch3, Karina Hofmann-Preiss4, Ina Boettger4, Ruediger Jakobs5, Hendrik Schulze-Koops6 and Johannes von Kempis1, 1Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Division of Rheumatoloy, Medizinische Klinik IV, University of Munich, Munich, Germany, 3Schwerpunktpraxis Rheumatologie, Erlangen, Germany, 4Institut für bildgebende Diagnostik und Therapie, Erlangen, Germany, 5Siemens AG, Erlangen, Germany, 6Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany

    Background/Purpose: The detection of joint swelling caused by synovitis is important for the diagnosis and assessment of inflammatory arthritis. Ultrasound (US) and MRI have proven…
  • Abstract Number: 1953 • 2013 ACR/ARHP Annual Meeting

    The Progression of Cartilage Damage in Rheumatoid Arthritis: A Three Year Prospective 3T- Magnetic Resonance Imaging Study Examining Predictive Factors

    Fiona M. McQueen1, Alexandra McHaffie2, Andrew Clarke2, Arier Lee3, Quentin Reeves2, Barbara Curteis1 and Nicola Dalbeth4, 1Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand, 2Radiology, Auckland District Health Board, Auckland, New Zealand, 3Biostatistics and Epidemiology, University of Auckland, Auckland, New Zealand, 4Auckland District Health Board, Auckland, New Zealand

    Background/Purpose: Cartilage damage impacts on patient disability in RA. The aims of this MRI study were to investigate cartilage damage over 3 years and determine…
  • Abstract Number: 1954 • 2013 ACR/ARHP Annual Meeting

    advantages Of a Combined Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) For Hand and Feet: Does The Ramris Of The Hand Alone Underestimate Disease Activity and Progression?

    Dr. Philipp Sewerin1, Dr. Christian Buchbender2, Dr. Stefan Vordenbäumen1, Dr. Axel Scherer2, Dr. Falk Miese2, Dr. Ralph Brinks3, Dr. Hans-Jörg Wittsack4, Prof. Dr. Gerald Antoch4, Prof. Dr. Matthias Schneider3 and Prof. Dr. Benedikt Ostendorf1, 1Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 3Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany, 4Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany

    Background/Purpose: To evaluate a combined rheumatoid arthritis magnetic resonance imaging score (RAMRIS) for hand and foot (HaF-score) in rheumatoid arthritis (RA). Methods: Magnetic resonance imaging…
  • Abstract Number: 1955 • 2013 ACR/ARHP Annual Meeting

    Biochemical MRI With Gagcest (Glycosaminoglycan Chemical Exchange Saturation Transfer Imaging) Of Finger Joint Cartilage In Rheumatoid Arthritis

    Dr. Philipp Sewerin1, Dr. Christoph Schleich2, Prof. Dr. Benedikt Ostendorf1, Dr. Stefan Vordenbäumen1, Prof. Dr. Gerald Antoch3, Prof. Dr. Matthias Schneider4 and Dr. Falk Miese5, 1Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, 3Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 4Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany, 5Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany

    Background/Purpose: Rheumathoid arthritis (RA) predominantly involves finger joints. Cartilage damage promotes synovitis and has previously been shown to be predictive for bone erosions. gagCEST has…
  • Abstract Number: 1956 • 2013 ACR/ARHP Annual Meeting

    The Effect Of Initial Methotrexate Therapy On Cartilage Composition In Early Rheumatoid Arthritis: Follow-Up With Biochemical MRI Of Finger Cartilage

    Dr. Philipp Sewerin1, Dr. Falk Miese2, Dr. Hans-Jörg Wittsack3, Dr. Stefan Vordenbäumen1, Dr. Christoph Schleich4, Prof. Dr. Gerald Antoch3, Prof. Dr. Matthias Schneider5 and Prof. Dr. Benedikt Ostendorf1, 1Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 3Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 4Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, 5Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany

    Background/Purpose: To test for initial status and subsequent recovery of cartilage glycosaminoglycane content in metacarpophalangeal joints (MCP) in patients with early rheumatoid arthritis (eRA) undergoing…
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