ACR Meeting Abstracts

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  • Abstract Number: 2008 • 2013 ACR/ARHP Annual Meeting

    Assessing Treat To Target In Gout Patients With and Without Tophi

    Leslie R. Harrold1, Carol Etzel2,3, Bruce Schechter4, Raymond L. Malamet5, Vanessa Cox2 and Jeffrey D. Greenberg6, 1University of Massachusetts Medical School, Worcester, MA, 2CORRONA, Inc, Southborough, MA, 3Department of Epidemiology, UT MD Anderson, Houston, TX, 4Savient Pharmaceuticals, Inc., Bridgewater, NJ, 5Global Medical Affairs, Savient Pharmaceuticals, Inc., Bridgewater, NJ, 6NYU Hospital for Joint Diseases, New York, NY

    Background/Purpose: Little is known regarding the differences in characteristics between patients with tophaceous gout compared to those without tophi.  We examined these differences in a…
  • Abstract Number: 1969 • 2013 ACR/ARHP Annual Meeting

    Ankle Joint Involvement In Rheumatoid Arthritis. An Ultrasound Study Using High Resolution- and Colour Doppler Ultrasound

    Mohammed Alsuwaidi1, Boris P. Ehrenstein1, Martin Fleck2 and Wolfgang Hartung1, 1Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, 2Internal Medicine I, University Medical Center of Regensburg, Regensburg, Germany

    Background/Purpose: Despite a pivotal role for RA patients mobility, the ankle joints are frequently neglected, and omitted in activity scoring systems including DAS 28. In…
  • Abstract Number: 1970 • 2013 ACR/ARHP Annual Meeting

    The Utility Of Fluorescence Optical Imaging For Detecting Clinically Silent Synovitis Of The Hands and Wrists

    Yogan Kisten1, Noémi Györi2, Hamed Rezaei3, Anna Karlsson1, Carolina Romanus2, Ronald van Vollenhoven4 and Erik af Klint5, 1Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute,Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Stockholm, Sweden, 2Unit for Clinical Therapy Research Inflammaroty Diseases (ClinTRID) Department of Medicine, the Karolinska Insitute, Stockholm, Sweden, 3Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, 4Unit for Clinical Research Therapy. Inflammatory Diseases (ClinTrid), Karolinska Institute, Stockholm, Sweden, 5Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The rheumatology clinic of the Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: The detection of subclinical synovial inflammation (“silent synovitis”) would be of critical importance for the detection of rheumatoid arthritis (RA) in its earliest pathophysiological…
  • Abstract Number: 1971 • 2013 ACR/ARHP Annual Meeting

    The Four Finger Examination Technique Is Superior To The Standard Two Finger Technique To Detect Metacarpal Phalangeal Joint Swelling In Rheumatoid Arthritis – A Validation By Power Doppler Ultrasound

    Mohammed Omair1, Pooneh Akhavan2, Ali Naraghi3, Deborah Weber4, Shikha Mittoo2, Melissa Weber4, Juan Xiong5 and Edward C. Keystone2, 1Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, 2Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, 3Musculoskeletal Radiology Joint Department of Medical Imaging, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, 4Mount Sinai Hospital, Toronto, ON, Canada, 5Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Swollen joints (SJs) are a strong clinical predictor of radiographic progression in rheumatoid arthritis (RA). The metacarpal phalangeal joints (MCP) SJs are particularly relevant…
  • Abstract Number: 1972 • 2013 ACR/ARHP Annual Meeting

    Erosion Case Definition and Scoring Reliability Exercise Using a New Outcome Measurement Tool, High-Resolution Peripheral Quantitative Computed Tomography, In Rheumatoid Arthritis

    Cheryl Barnabe1, Dominique Toepfer2, Hubert Marotte3, Ellen-Margrethe Hauge4, Andrea Scharmga5, Roland Kocijan6, Sebastian Kraus7, Kresten K. Keller4, Joost de Jong8, Jeroen Williams8 and Stephanie Finzel7, 1Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, 2Institute of Medical Physics, University of Erlangen-Nuremberg, Erlangen, Germany, 3Rheumatology Department, University Hospital of Saint-Étienne, Inserm U1059, Saint-Etienne, France, 4Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 5Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 6Academic Teaching Hospital of Medical University Vienna, Vienna, Austria, 7Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 8Maastricht University, Maastricht, Netherlands

    Background/Purpose: High-resolution peripheral quantitative computed tomography (HR-pQCT) is a novel imaging instrument for bony damage in rheumatoid arthritis (RA). Agreement on a case definition for…
  • Abstract Number: 1973 • 2013 ACR/ARHP Annual Meeting

    Importance Of Hand Positioning In 3D Joint Space Morphology Assessment

    Stephanie Boutroy1, Elodie Hirschenhahn1, Emile Youssof2, Hervé Locrelle2, Thierry Thomas2, Roland Chapurlat3 and Hubert Marotte2, 1INSERM U1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, 2INSERM U1059 and University Hospital, Hôpital Nord, Saint-Etienne, France, 3INSERM UMR 1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France

    Background/Purpose: Precise quantification of joint space morphology (JSM) is an important factor for early diagnosis and monitoring of disease activity and therapeutic responses in rheumatoid…
  • Abstract Number: 1974 • 2013 ACR/ARHP Annual Meeting

    Assessing Validity Of Low Field Magnetic Resonance Imaging (MRI) for  Joint Inflammation and Damage In Wrist/Hand Rheumatoid Arthritis (RA) – A Systematic Literature Review (SLR)

    OM Troum1, OL Pimienta1, TG Woodworth2, O Morgacheva3, V Ranganath4 and Daniel Furst5, 1Keck School of Medicine, University of Southern California, Los Angeles, CA, 2Medicine, Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, CA, 3Medicine/Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, CA, 4Medicine, Division of Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 5David Geffen School of Medicine, University of California, Los Angeles, CA

    Background/Purpose: Radiographic scoring of erosions and joint space narrowing (JSN) of the hand/wrist is standard to evaluate RA joint damage for regulatory approval of DMARDs;…
  • Abstract Number: 1975 • 2013 ACR/ARHP Annual Meeting

    Cardiovascular Risk Stratification In Rheumatic Diseases : Carotid Ultrasound Is More Sensitive Than Coronary Artery Calcification Score To Detect Subclinical atherosclerosis In Patients With Rheumatoid Arthritis

    Francisco Ortiz-Sanjuán1, Alfonso Corrales2, José Antonio Parra3, Carlos González-Juanatey4, Montserrat Santos5, Javier Rueda6, Ricardo Blanco7, Vanesa Calvo-Río8, Javier Loricera8, Javier Llorca9 and Miguel A González-Gay10, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 3Radiology Division, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 4Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, 5Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, 6Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 7Hospital Marques de Valdecilla, Santander, Spain, 8Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 9Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, 10Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain

    Background/Purpose: Rheumatoid arthritis (RA) is a disease associated to accelerated atherogenesis leading to increased incidence of cardiovascular (CV) mortality. Adequate stratification of the CV risk…
  • Abstract Number: 1976 • 2013 ACR/ARHP Annual Meeting

    Magnetic Resonance Imaging-Assessment Of Early Response To Certolizumab Pegol In Rheumatoid Arthritis: A Randomized, Double-Blind, Placebo-Controlled Phase IIIb Study Applying Magnetic Resonance Imaging At Week 0, 1, 2, 4, 8 and 16

    Mikkel Ostergaard1, Lennart Jacobsson2, Christopher Schaufelberger3, Michael Sejer-Hansen4, Johannes Bijlsma5, Anna Dudek6, Maria Rell-Bakalarska7, Fabienne Staelens8, Robert Haake9, Britt Sundman-Engberg10 and Henning Bliddal11, 1Copenhagen Center for Arthritis Research, Glostrup, Denmark, 2Department of Clinical Sciences, Section of Rheumatology, Malmö, Sweden, 3Department of Rheumatology & Inflammation Research, Sahlgrens' Hospital, Göteborg, Sweden, 4Rheumatology Clinic, Copenhagen, Denmark, 5Deptartment of Rheumatology & Immunity, University Medical Center, Utrecht, Netherlands, 6Medica Pro Familia, Warsaw, Poland, 7Rheuma Medicus, Warsaw, Poland, 8UCB Pharma, Brussels, Belgium, 9UCB Pharma, Raleigh, NC, 10UCB Pharma, Stockholm, Sweden, 11Department of Rheumatology, The Parker Institute, Frederiksberg, Denmark

    Background/Purpose: The OMERACT rheumatoid arthritis (RA) magnetic resonance imaging (MRI) scoring system (RAMRIS) is a validated scoring system for assessment of synovitis, bone edema and…
  • Abstract Number: 1977 • 2013 ACR/ARHP Annual Meeting

    Remission At 3 Or 6 Months and Radiographic Non-Progression At 12 Months In Methotrexate-Naïve Rheumatoid Arthritis Patients Treated With Tofacitinib Or Methotrexate: A Post-Hoc Analysis Of The ORAL Start Trial

    V. Strand1, D. van der Heijde2, R. Landewe3, E. B. Lee4, B. Wilkinson5, S. H. Zwillich5, J. Bradley5, C. Mebus5, B. Benda6 and D. Gruben5, 1Adjunct, Division of Immunology / Rheumatology, Stanford University, Palo Alto, CA, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, 4Seoul National University, Seoul, South Korea, 5Pfizer Inc, Groton, CT, 6Pfizer Inc, Collegeville, PA

    Background/Purpose: Tofacitinib is a novel, oral Janus kinase (JAK) inhibitor for the treatment of RA. The importance of “treat to target” in RA to attain…
  • Abstract Number: 1978 • 2013 ACR/ARHP Annual Meeting

    The Effect Of Certolizumab On Lymphatic Volume and Flow In Rheumatoid Arthritis Patients With Acute Flare

    Homaira Rahimi1, Vaseem Chengazi2, Gregory Dieudonne2, Edward M. Schwarz3 and Christopher T. Ritchlin4, 1Pediatrics, University of Rochester, Rochester, NY, 2Radiology, University of Rochester, Rochester, NY, 3Center for Musculoskeletal Research, University of Rochester, Rochester, NY, 4Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY

    Background/Purpose: Episodic flare occurs in rheumatoid arthritis (RA) but the mechanisms of this process are not well understood. Our prior reports on MRI analysis of…
  • Abstract Number: 1979 • 2013 ACR/ARHP Annual Meeting

    Occupational Balance Questionnaire: From People’s Perspectives To A Patient Reported Outcome

    Mona Dür1, Gunter Steiner2, Michaela Stoffer3, Alexandra Kautzky-Willer4, Veronika Fialka-Moser5, Clemens Dejaco6, Birgit Prodinger7, Alexa Binder8, Josef S. Smolen9,10 and Tanja A. Stamm11, 1Internal Medicine III Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Internal Medicine III, division of rheumatology, Medical University of Vienna, Vienna, Austria, 4Internal Medicine III, Division of Diabetology, Medical University of Vienna, Vienna, Austria, 5Physical Medicine and Rehabilitation, Medical University of Vienna, Vienna, Austria, 6Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria, 7ICF Research Branch, Swiss Paraplegic Group, Nottwil, Switzerland, Notwill, Switzerland, 8Occupational therapy, Hospital Goettlicher Heiland, Vienna, Austria, 9Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 10Department of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 11Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: Occupational balance is one of the foundations on which occupational therapy is based. Occupational balance is defined diversely and mainly derived from the perspective…
  • Abstract Number: 1980 • 2013 ACR/ARHP Annual Meeting

    Validation Of The Fox-Walk Test In People With Rheumatoid Arthritis

    Birgitta Nordgren1, Cecilia Fridén2, Eva Jansson3, Ted Österlund4, Wilhelmus Johannes Andreas Grooten2, Christina H. Opava1 and Anette Rickenlund4,5, 1Neurobiology, Care Sciences and Society, Division of Physical Therapy, Karolinska Institutet, Huddinge, Sweden, 2Neurobiology, Care Sciences and Society, Division of Physical Therapy, Karolinska Institutet, SE 14183 Huddinge, Sweden, 3Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden, 4Karolinska University Hospital, Huddinge, Sweden, 5Department of Molecular Medicine and Surgery, Karolinska Institutet, Huddinge, Sweden

    Background/Purpose: Aerobic capacity tests are important to evaluate exercise programs and to encourage individuals to a physically active lifestyle. Maximum aerobic tests in a laboratory…
  • Abstract Number: 1981 • 2013 ACR/ARHP Annual Meeting

    Developing International Consensus Definitions Of Improvement For Adult and Juvenile Dermatomyositis and Polymyositis

    Saad Feroz1, Nicolino. Ruperto2, Jiri Vencovsky3, Peter A. Lachenbruch1, Brian Erman4, Adam Huber5, Brian M. Feldman6, Ingrid E. Lundberg7, Angela Pistorio8, Howard Rockette9, Frederick W. Miller1, Rohit Aggarwal10, Lisa G. Rider1, for The ACR-EULAR Myositis Response Criteria Project Group11, Angelo Ravelli12, Clarissa Pilkington13 and Sheila K. Oliveira14, 1Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 2PRINTO, IRCCS G. Gaslini, Genoa, Italy, 3Institute of Rheumatology, Department of Clinical and Experimental Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 4SRA International, Research Triangle Park, NC, 5IWK Health Centre, Halifax, NS, Canada, 6Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 7Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, 8PRINTO, Genoa, Italy, 9University of Pittsburgh, Pittsburgh, PA, 10Medicine / Rheumatology, University of Pittsburgh, Pittsburgh, PA, 11NIEHS, NIH, Bethesda, MD, 12Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, 13Rheumatology Department, Great Ormond Street Hospital, London, United Kingdom, 14Pediatric Rheumatology, Instituto de Pediatria e Puericultura Martagão Gesteira (IPPMG) da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil

    Background/Purpose: IMACS and PRINTO have developed preliminary core set activity measures and definitions of improvement (DOIs). However, these were developed from small and partially retrospective…
  • Abstract Number: 1982 • 2013 ACR/ARHP Annual Meeting

    Development and Validation Of Medication Assessment Tools Specific For Rheumatoid Arthritis

    Louise Grech1,2, Bernard Coleiro1,3, Anthony Serracino Inglott1, Lilian M. Azzopardi1, Victor Ferrito1 and Andrew A. Borg3,4, 1Pharmacy, University of Malta, Msida, Malta, 2Clinical Pharmacy, Mater Dei Hospital, Msida, Malta, 3Medicine, Mater Dei Hospital, Msida, Malta, 4Medicine, University of Malta, Msida, Malta

    Background/Purpose: Medication assessment tools can be defined as evidence-based instruments intended for the evaluation of prescribing trends and monitoring of adherence to established guidelines. Medication…
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