ACR Meeting Abstracts

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  • Abstract Number: 2173 • 2013 ACR/ARHP Annual Meeting

    The Interleukin-1 Receptor Antagonist Anakinra Is Effective In The Treatment Of Undifferentiated Periodic Fever Syndromes

    Daniella M. Schwartz1, Runsheng Wang2, Karyl Barron3, Daniel L. Kastner4 and Amanda K. Ombrello5, 1Rheumatology fellowship and training branch, National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 2NIH/NIAMS, Rheumatology fellowship and training branch, Bethesda, MD, 3Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 4Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, MD, 5National Human Genome Research Institute,National Institute of Health, Bethesda, MD

    Background/Purpose: The autoinflammatory diseases are a group of disorders associated with dysregulation of the innate immune system. They are characterized by recurrent episodes of fever…
  • Abstract Number: 2174 • 2013 ACR/ARHP Annual Meeting

    Urinalysis Monitoring In Children With Henoch-Schönlein Purpura: Is It Time To Revise?

    Hao Wang1, Manasita Tanya2, Justin Hung Tiong Tan2, Sook Fun Hoh3, Lena Das4 and Thaschawee Arkachaisri5, 1Paediatrics, Duke-NUS Graduate Medical School, Singapore, Singapore, 2Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, 3Nursing, KK Women's and Children's Hospital, Singapore, Singapore, 4Pediatric Rheumatology, KK Women's and Children's Hospital, Singapore, Singapore, 5Rheumatology & Immunology, KK Women's and Children's Hospital and Duke-NUS Graduate Medical School, Singapore, Singapore

    Background/Purpose: Major complication of Henoch-Schönlein Purpura (HSP) is renal impairment. Recommended urinalysis (UA) monitoring over a period of 2 years has been a common practice…
  • Abstract Number: 2175 • 2013 ACR/ARHP Annual Meeting

    Systematic Analysis and Pathologic Findings In Young Adults With Sudden Death Attributed To Kawasaki Disease In Childhood

    Chisato Shimizu1, Alka Sood1, Hubert Lau1, Steven Campman2 and Jane C. Burns1, 1Pediatrics, UC San Diego, School of Medicine, La Jolla, CA, 2San Diego County Medical Examiner Office, La Jolla, CA

    Background/Purpose: Coronary artery aneurysms (CAA) may remain silent after Kawasaki disease (KD) until adulthood when myocardial ischemia can lead to sudden death. CAA attributed to…
  • Abstract Number: 2177 • 2013 ACR/ARHP Annual Meeting

    A Pilot Study Of Juvenile Localized Scleroderma (jLS) Consensus Treatment Plans

    Suzanne C. Li1, Kathryn S. Torok2, Mara L Becker3, Fatma Dedeoglu4, Robert C. Fuhlbrigge5, Gloria C. Higgins6, Sandy D. Hong7, Maria F. Ibarra8, Ronald M. Laxer9, Thomas G. Mason II10, Elena Pope11, Marilynn G. Punaro12,13, C. Egla Rabinovich14, Katie G. Stewart12, Christina Kelsey15, Brian Feldman16, Themba Nyrienda17 and Knut M. Wittkowski18, 1Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 2Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 3Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, 4Division of Immunology, Boston Children's Hospital, Boston, MA, 5Pediatric Rheumatology, Childrens Hospital, Boston, MA, 6Pediatric Rheumatology Ohio State University, Nationwide Childrens Hosp, Columbus, OH, 7Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, 8Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, 9Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 10Rheumatology, Mayo Clinic Rochester, Rochester, MN, 11Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, 12Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, 13Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, 14Duke University Medical Center, Durham, NC, 15Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 16Rheumatology, Hospital for Sick Kids, Toronto, ON, Canada, 17Research, Hackensack University Medical Center, Hackensack, NJ, 18Center for Clinical and Translational Science, Rockefeller University, New York, NY

    Background/Purpose: Purpose: To evaluate clinical assessment tools and standardized treatment regimens (consensus treatment plans, CTPs) developed for juvenile localized scleroderma (jLS)  jLS is a chronic, inflammatory…
  • Abstract Number: 2178 • 2013 ACR/ARHP Annual Meeting

    Juvenile Onset Systemic Sclerosis: Clinical and Serological Features, and Mortality In Comparison With Adult Onset Disease

    Juan G. Ovalles-Bonilla1, Francisco Javier López-Longo2, Indalecio Monteagudo1, Esperanza Naredo1, Carlos Gonzalez Fernandez1, María Montoro Alvarez1, Lina Martínez-Estupiñán1, Juan C. Nieto3, Julia Martínez-Barrio1, Michelle Hinojosa1, Natalia Bello1, Belen Serrano1, Carmen Mata1 and Luis Carreño1, 1Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Hospital General Universitario Gregorio Marañón, Department of Rheumatology, Madrid, Spain, 3Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Background/Purpose: Currently data regarding long-term outcome of juvenile systemic sclerosis (jSSc) is scarce. To describe the differences between patients with jSSc versus adult onset evaluated at a single medical…
  • Abstract Number: 2179 • 2013 ACR/ARHP Annual Meeting

    Consensus: What Agent To Use When First-Line Vasodilatadors Fail In Raynaud´s Phenomenon Or Digital Ulcers Secondary To Juvenile Systemic Sclerosis?

    Marìa M. Katsicas1, Mariana Gonzalez2 and Ricardo A. G. Russo3, 1Immunology & Rheumatology., Hospital de Pediatrìa Garrahan, Buenos Aires, Argentina, 2Immunology & Rheumatology, Hospital de Pediatría Garrahan, Buenos Aires, Argentina, 3Immunology & Rheumatology, Hospital de Pediatria Garrahan, Buenos Aires, Argentina

    Background/Purpose: Juvenile Systemic Sclerosis (JSS) is characterized by Raynaud`s phenomenon (RP) and digital ulcers (DU).Conventional therapy includes calcium channel blockers (CCB). A growing number of…
  • Abstract Number: 2180 • 2013 ACR/ARHP Annual Meeting

    Presentation, Diagnosis, and Treatment Of Chronic Recurrent Multifocal Osteomyelitis

    Colin Anderson1, Erin Wylie2, Travis Heare3, Jamie Stewart4, Kelley Capocelli5, Shelley Dell'Orfano3 and Jennifer Soep6, 1Orthopaedic Surgery, The University of Colorado, Aurora, CO, 2Musculoskeletal Research Center, Children’s Hospital Colorado, Aurora, CO, 3Orthopaedic Surgery, Children’s Hospital Colorado, Aurora, CO, 4Pediatric Radiology, Children’s Hospital Colorado, Aurora, CO, 5Pediatric Pathology, Children’s Hospital Colorado, Aurora, CO, 6Pediatric Rheumatology, Children’s Hospital Colorado, Aurora, CO

    Background/Purpose: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare, non-infectious inflammatory bone disorder in children. Knowledge about the disorder is limited secondary to its rare…
  • Abstract Number: 2181 • 2013 ACR/ARHP Annual Meeting

    Methotrexate and Infliximab With Or Without Zoledronic Acid Improve Disease Activity and Prevent Damage Progression In Chronic Nonbacterial Osteomyelitis

    Yongdong (Dan) Zhao1, Nancy Chauvin2, Diego Jaramillo2 and Jon Burnham3, 1Rheumatology, Children's Hospital of Philadelphia, PHILADELPHIA, PA, 2Radiology, Children's Hospital of Philadelphia, PHILADELPHIA, PA, 3Pediatrics, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Chronic nonbacterial osteomyelitis (CNO) is an inflammatory bone disease that causes pain, disability, and sometimes permanent skeletal damage. MRI allows for visualization of bone…
  • Abstract Number: 2182 • 2013 ACR/ARHP Annual Meeting

    Spectrum Of Musculoskeletal Inpatient Diagnoses At The Largest Pediatric Center In East Africa In 2011

    Angela Migowa1, Ines Colmegna2, Evelyne Ng'ang'a3, John Wachira4, Thomas Ngwiri5, Carol A. Hitchon6, Sasha Bernatsky7 and Rosie Scuccimarri8, 1Pediatrics, Aga Khan University Hospital, Nairobi, Kenya, 2Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 3Pediatrics, University of Nairobi, Nairobi, Kenya, 4Pediatrics, Gertrude's Children Hospital, Nairobi, Kenya, 5Pediatrics, Gertrude's Children's Hospital, Nairobi, Kenya, 6Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 7Division of Clinical Epidemiology, McGill University Health Center, Montreal, QC, Canada, 8McGill University, Montreal, QC, Canada

    Background/Purpose: Pediatric rheumatic diseases are among the most common chronic illnesses of childhood and can cause considerable disease burden and disability. The frequency and outcomes…
  • Abstract Number: 2183 • 2013 ACR/ARHP Annual Meeting

    Spectrum Of Outpatient Musculoskeletal Visits At The Largest Pediatric Center In East Africa In 2011

    Laurel Broten1, Angela Migowa2, Rosie Scuccimarri3, Evelyne Ng'ang'a4, John Wachira5, Thomas Ngwiri6, Sasha Bernatsky7, Carol A. Hitchon8 and Ines Colmegna9, 1Rheumatology, McGill University, Montreal, QC, Canada, 2Pediatrics, Aga Khan University Hospital, Nairobi, Kenya, 3McGill University, Montreal, QC, Canada, 4Pediatrics, University of Nairobi, Nairobi, Kenya, 5Pediatrics, Gertrude's Children Hospital, Nairobi, Kenya, 6Pediatrics, Gertrude's Children's Hospital, Nairobi, Kenya, 7Division of Clinical Epidemiology, McGill University Health Center, Montreal, QC, Canada, 8Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 9Rheumatology, McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Pediatric rheumatic diseases are a major cause of morbidity, frequently leading to permanent disability, impaired functional status and quality of life, and significant direct…
  • Abstract Number: 2184 • 2013 ACR/ARHP Annual Meeting

    Application Of The Bonexpert Method For Bone Age and Bone Health Assessment In Patients With Juvenile Idiopathic Arthritis

    Charlotte M. Nusman1, Janneke Anink2, Lisette W.A. van Suijlekom-Smit2, Marion A.J. van Rossum3, Mario Maas4 and Rick R. van Rijn4, 1Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 2Pediatric Rheumatology, Erasmus MC Sophia Children's Hospital, Rotterdam, Netherlands, 3Department of Pediatric Rheumatology and Immunology, Emma Children's Hospital / Academic Medical Center and Reade Institute, Amsterdam, Netherlands, 4Radiology, Academic Medical Center, Amsterdam, Netherlands

    Background/Purpose: Both the maturation of bone and its mineral density are affected by chronic inflammation in juvenile idiopathic arthritis (JIA). Bone age is in most…
  • Abstract Number: 2185 • 2013 ACR/ARHP Annual Meeting

    Three Middle Finger Width Correlates With Maximum Mouth Opening and Is a New Reliable Parameter To Identify Joint Hypermobility In Schoolchildren

    Francesca Sperotto1, Gabriella La Falce2, Fabio Vittadello1, Lorenzo Favero2 and Francesco Zulian3, 1Department of Pediatrics, University of Padua, Padua, Italy, 2Gnatology Unit, Department of Dentistry, Padua, Italy, 3PRINTO, Genoa, Italy

    Background/Purpose: Maximum mouth opening (MMO) is a useful parameter to identify common temporomandibular joint (TMJ) disorders. Up to now, a few studies addressed the issue…
  • Abstract Number: 2186 • 2013 ACR/ARHP Annual Meeting

    Lower Extremity Strength Is Related To Diminished Quality Of Life In Obese Children

    Sharon M. Bout-Tabaku1,2, Matt Briggs3, Tom Best2, Colleen Spees2, Ajit Chaudhari2 and Laura Schmitt4, 1Rheumatology, Nationwide Children's Hospital, Columbus, OH, 2The Ohio State University, Columbus, OH, 3School of Health and Rehabilitation Sciences, Division of Physical Therapy, The Ohio State University, Columbus, OH, 4Health and Rehabilitation Science, The Ohio State Universtiy, Columbus, OH

    Background/Purpose: Obese children have a higher prevalence of lower extremity (LE) pain, with associated diminished quality of life, greater knee malalignment, generate less knee extensor…
  • Abstract Number: 2187 • 2013 ACR/ARHP Annual Meeting

    Inter-Rater Reliability Of Jumping Mechanography In Healthy Children and Adults

    Johannes Roth1, Ciaran M. Duffy2, Tania Bennett1, Marta Erlandson3, Michele Gibbon4, Heather Macdonald5, Douglas Race6, Leanne M. Ward1 and Lori B. Tucker7, 1University of Ottawa, Ottawa, ON, Canada, 2Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, 3University of Toronto, Toronto, ON, Canada, 4Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, 5The University of British Columbia, Vancouver, BC, Canada, 6University of British Columbia, Vancouver, BC, Canada, 7Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Muscle function can be affected by many chronic disorders of childhood including Juvenile Idiopathic Arthritis (JIA). Whereas the term “muscle strength” is often used…
  • Abstract Number: 2188 • 2013 ACR/ARHP Annual Meeting

    Role of Interleukin-1 in Abnormal Monocyte Phenotype in Systemic Onset Juvenile Idiopathic Arthritis

    Yujuan Zhang1,2, Claudia Macaubas2, Clarissa Klein3, M. Virginia Pascual4, Arielle Hay5, Susan D. Thompson6, Christy I. Sandborg3, Norman T. Ilowite7 and Elizabeth D. Mellins8, 1Pediatrics, Stanford University Med Ctr, Palo Alto, CA, 2Pediatric Rheumatology, Stanford University Med Ctr, Stanford, CA, 3Stanford University Med Ctr, Stanford, CA, 4Baylor Institue for Immunology Research, Dallas, TX, 5The Children's Hospital at Montefiore, Bronx, NY, 6Department of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, 8Dept of Pediatrics CCSR, Stanford University Medical Center, Stanford, CA

    Background/Purpose: Monocytes undergo phenotype changes when exposed to different microenvironments: the classic proinflammatory M1 phenotype, alternative regulatory M2 phenotype and M2-like phenotype, are each regulated…
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