Abstracts Archive - Page 2102 of 2425 - ACR Meeting Abstracts

Abstract Number: 2234 • 2013 ACR/ARHP Annual Meeting
Targeting Therapy Of Citrullinated Antigen-Specific B Cells Ameliorates Collagen-Induced Arthritis
Kazuya Michishita¹, Kimito Kawahata¹, Takeyuki Kanzaki², Lisa Akahira¹, Toshiki Eri¹ and Kazuhiko Yamamoto³, ¹Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, ²Internal Medicine, Yamanashi Prefectural Central Hospital, Yamanashi, Japan, ³Department of Allergy and Rhaumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Background/Purpose: The clinical benefit of B-cell depletion therapy in rheumatoid arthritis(RA) is a well-known fact, but problems such as relapse of tuberculosis and reactivation of…
Abstract Number: 2235 • 2013 ACR/ARHP Annual Meeting
Fas Signaling In Macrophages Promotes Chronicity In K/BxN Serum Transfer Induced Arthritis
Qi Quan Huang¹, Robert Birkett², Renee E. Koessler¹, Carla M. Cuda³, J.-P. Jin⁴, Harris R. Perlman⁵ and Richard M. Pope⁶, ¹Medicine/Rheumatology, Northwestern University, Chicago, IL, ²Medicine/Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL, ³Medicine / Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Physiology, Wayne State University, Detroit, MI, ⁵Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL
Background/Purpose: A non-apoptotic role for Fas signaling has been implicated in the regulation of inflammation and innate immunity. These studies were performed to elucidate the…
Abstract Number: 2236 • 2013 ACR/ARHP Annual Meeting
Articular Inflammation Is Protected By Fat-1 During The Acute Phase Of Arthritis In Mice
Sang-Il Lee¹, Yun-Hong Cheon², Ji-Min Kim³ and Won Seok Lee², ¹Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ²Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea
Background/Purpose: Omega-3 polyunsaturated fatty acids (n-3 PUFA) are well known to exert anti-inflammatory effects. The Fat-1 transgenic (Fat-1 TG) mice are capable of producing n-3…
Abstract Number: 2237 • 2013 ACR/ARHP Annual Meeting
Assessment Of Wage and Salary Growth In Patients With Rheumatoid Arthritis (RA)
Martin J. Bergman¹, Gourab De², Arijit X. Ganguli³, James Signorovitch⁴ and Yanjun Bao⁵, ¹Taylor Hospital, Ridley Park, PA, ²Analysis Group, Inc., New York, NY, ³AbbVie, Inc., North Chicago, IL, ⁴Analysis Group, Inc., Boston, MA, ⁵AbbVie Inc., North Chicago, IL
Background/Purpose: RA negatively impacts patients' work outcomes. Treatment with tumor necrosis factor inhibitors (anti-TNFs) has been associated with improved work productivity and stability in RA.…
Abstract Number: 2238 • 2013 ACR/ARHP Annual Meeting
Comparison Of The Long-Term Outcome For Rheumatoid Arthritis Patients With persistent Moderate Disease Activity Or Disease Remission During The First Year After Diagnosis: Data From The Espoir Cohort
Bernard Combe¹, Isabelle Logeart², M. Belkacemi³, S Dadoun⁴, Jean-Pierre Daurès⁵ and Maxime Dougados⁶, ¹Rheumatology, Lapeyronie Hospital, Montpellier I university, Montpellier, France, ²Pfizer, Paris, France, ³CHRU Montpellier, Montpellier, France, ⁴Paris-Pitié Salpêtrière University Hospital, Paris, France, ⁵Service BESPIM, CHU, Nimes, France, ⁶Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France
Background/Purpose: The Treat to Target and EULAR recommendations highlighted the need for achieving and maintaining remission in patients with early RA. We investigated if early…
Abstract Number: 2239 • 2013 ACR/ARHP Annual Meeting
Validation Of a Patient Reported Experience Measure In Patients With Rheumatoid Arthritis
Marwan Bukhari¹, Peter Jones², Ifeanyi Sargeant³, Maureen Cox⁴, Alison Elliott⁵, Suzanne Bullock⁶, Anne O'Brien² and Ailsa Bosworth⁷, ¹Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom, ²Keele University, Keele, United Kingdom, ³IS medical communications, Stafford, United Kingdom, ⁴Nuffield Orthopaedic centre, Oxford, United Kingdom, ⁵Roche Pharmaceuticals, Welwyn Garden City, United Kingdom, ⁶Lancaster University, Lancaster, United Kingdom, ⁷National Rheumatoid Arthritis Society, Maidenhead, United Kingdom
Background/Purpose: Improving patient experience is important in all diseases, but most important in patients with chronic rheumatic diseases like rheumatoid arthritis. To date there…
Abstract Number: 2240 • 2013 ACR/ARHP Annual Meeting
Correlative Analysis Of Swollen Joints Between Clinical Examination and Musculoskeletal Ultrasound For Rheumatoid Arthritis
Kenta Misaki¹, Takashi Nakazawa², Shunichi Fujita¹, Hirotaka Yamada¹ and Toshihiko Yokota¹, ¹Rheumatology, Kurashiki Central Hospital, Kurashiki, Japan, ²Rheumatology, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan
Background/Purpose: The disease activity score 28 (DAS28), clinical disease activity index (CDAI) and simplified disease activity index (SDAI) are all used in the clinical assessment…
Abstract Number: 2241 • 2013 ACR/ARHP Annual Meeting
Assessing Significant Flares In Rheumatoid Arthritis: Validity Of The Outcome Measures In Rheumatology Preliminary Flare Questions In The Canadian Early Arthritis Cohort
Susan J. Bartlett^1,2, Clifton O. Bingham III³, Ernest Choy⁴, Juan Xiong⁵, Gilles Boire⁶, Boulos Haraoui⁷, Janet E. Pope^8,9, J. Carter Thorne¹⁰, Carol A. Hitchon¹¹, Diane Tin¹², Edward C. Keystone¹³ and Vivian P. Bykerk^13,14, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁵Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁶Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁷Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ⁸St Joseph Health Care, London, ON, Canada, ⁹Univ of Western Ontario, London, ON, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ¹⁴Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) flares are common, poorly defined, and understudied. A tool is needed to measure significant RA flares that may signal need for…
Abstract Number: 2242 • 2013 ACR/ARHP Annual Meeting
Patient Versus Physician Joint Counts In Rheumatoid Arthritis Utilizing a Unique Self-Joint Examination Tool
Daisy Bang¹, Yomei Shaw², Christine L. Amity³, Kelly A. Reckley⁴, Ilinca D. Metes⁵ and Marc C. Levesque⁶, ¹Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, ²Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, ³Rheumatology & Clinical Immun, Univ of Pittsburgh, Pittsburgh, PA, ⁴Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁶Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The quantitative assessment of disease activity has been endorsed by the American College of Rheumatology (ACR) to improve rheumatoid arthritis (RA) outcomes. To facilitate…
Abstract Number: 2243 • 2013 ACR/ARHP Annual Meeting
How Well Do The Three Generic Patient Reported Outcomes Measurement Information System Fatigue Instruments Perform In Rheumatoid Arthritis?
Susan J. Bartlett^1,2, Ana-Maria Orbai³, Trisha Duncan³ and Clifton O. Bingham III³, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD
Background/Purpose: NIH Patient-Reported Outcomes Measurement Information System (PROMIS) has created highly precise and efficient instruments to measure patient-reported outcomes across health domains relevant to chronic…
Abstract Number: 2244 • 2013 ACR/ARHP Annual Meeting
Diagnostic Accuracy Of Anti-Ccp Testing For Detecting Prevalent Rheumatoid Arthritis: Results From Screening a Population Based Cohort
Aase Haj Hensvold¹, Patrik KE Magnusson², Lena Israelsson³, Monika Hansson⁴, Vijay Joshua¹, Rikard Holmdahl⁵, Per-Johan Jakobsson³, Johan Askling⁶, Vivianne Malmström⁷, Lars Klareskog³ and Anca I Catrina³, ¹Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ²Medical Epidemiology and Biostatistics, Swedish Twin Registry Karolinska Institutet, Stockholm, Sweden, ³Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, ⁴Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden, ⁶Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁷Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Anti-CCP testing is a part of the clinical routine investigations for rheumatoid arthritis (RA). Previous studies have relative few included controls per patients. We therefor…
Abstract Number: 2245 • 2013 ACR/ARHP Annual Meeting
Predictive Validity Of Low Disease Activity Using Patient Reported Measures On Long-Term Outcomes In Early Rheumatoid Arthritis- Results From Study Of New Onset Rheumatoid Arthritis and Ontario Best Practices Initiative
Pooneh Akhavan¹, Binu Jacob², Paul R. Fortin³, George A. Tomlinson⁴ and Claire Bombardier^5,6, ¹Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ²University Health Network, Toronto General Research Institute, Toronto, ON, Canada, ³University of Laval, Quebec, QC, Canada, ⁴Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada, ⁵Rheumatology, University of Toronto, Toronto, ON, Canada, ⁶Division of rheumatology and Department of Health Policy, Management, and Evaluation, University Health Network, Toronto, ON, Canada
Background/Purpose: Patient reported outcome measures (PROM) are used in routine practice for assessment of disease activity. They have been shown to correlate well with other…
Abstract Number: 2246 • 2013 ACR/ARHP Annual Meeting
Patients’ Assessment of the Disease Greatly Influences the Determination of Disease Activity and Remission in Rheumatoid Arthritis
Kenrin Shi^1,2, Kenji Miki^1,3, Masao Yukioka¹, Kosuke Ebina², Shoichi Kaneshiro² and Hideki Yoshikawa², ¹Department of Orthopaedic Surgery, Yukioka Hospital, Osaka, Japan, ²Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan, ³Department of Orthopaedic Surgery, Amagasaki Central Hospital, Amagasaki, Japan
Background/Purpose: Recently defined remission criteria of rheumatoid arthritis (RA), Boolean criteria or Simplified Disease Activity Index (SDAI)
Abstract Number: 2247 • 2013 ACR/ARHP Annual Meeting
Response To a Sleep Query On The Multi-Dimensional Health Assessment Questionnaire (MDHAQ) Is Related To Levels Of Disease Activity
Martin J. Bergman^1,2, Sapna Sangani³, Isabel Castrejón⁴ and Theodore Pincus⁴, ¹Medicine, Drexel University College of Medicine, Philadelphia, PA, ²Taylor Hospital, Ridley Park, PA, ³Medicine, Mercy Catholic Medical Center, Lansdowne, PA, ⁴Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Patients with rheumatoid arthritis (RA) often report fatigue, but a possible impact of disease on sleep and/or on disease activity are poorly characterized. We…
Abstract Number: 2248 • 2013 ACR/ARHP Annual Meeting
Difference Between The Two Versions Of Disease Activity Score Based On C-Reactive Protein and Erythrocyte Sedimentation Rate
Pinar Cetin¹, Dilek Solmaz¹, Hacer Gulluoglu², Ismail Sari¹, Merih Birlik¹, Servet Akar¹, Fatos Onen¹ and Nurullah Akkoc¹, ¹Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey, ²Internal Medicine, Dokuz Eylul University School of Medicine, Ýzmir, Turkey
Background/Purpose: In some countries reimbursement criteria require a DAS28 score of >5.1 for initiating anti-TNF therapy in patients with rheumatoid arthritis. DAS28 score can be…

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