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  • Abstract Number: 2087 • 2014 ACR/ARHP Annual Meeting

    Defective Regulation of L1 Endogenous Retroelements in Primary Sjogren’s Syndrome and Systemic Lupus Erythematosus: Role of Methylating Enzymes

    Clio Mavragani1, Adrianos Nezos2, Irina Sagalovskiy3, Surya V. Seshan4, Kyriakos A. Kirou5, Haralampos M. Moutsopoulos6 and Mary K. Crow3, 1Department of Physiology, School of Medicine, University of Athens, Athens, Greece, 2Department of Physiology, School of Medicine, University of Athens, Athens, Greece, 3Department of Medicine, Hospital for Special Surgery, New York, NY, 4Pathology and Laboratory Medicine, Hospital for Special Surgery, New York, NY, 5Hospital for Special Surgery, New York, NY, 6Department of Pathophysiology, School of Medicine, University of Athens, Athens, Greece

    Background/Purpose: To investigate whether deranged methylating mechanisms are involved in the inappropriate expression of LINE-1 (L1) retroelements in primary Sjogren’s syndrome (SS) and systemic lupus…
  • Abstract Number: 2086 • 2014 ACR/ARHP Annual Meeting

    Replication of PTPRC As Genetic Biomarker of Response to TNF Inhibitors in Patients with Rheumatoid Arthritis

    Antonio Gonzalez1, Aida Ferreiro-Iglesias2, Juan Gomez-Reino3 and on Behalf of Their Collaborators4, 1Laboratorio Investigacion 10 and Rheumatology Unit, Instituto Investigacion Sanitaria- Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, 2Insitituto Investigacion Sanitaria- Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, 3Instituto Investigacion Sanitaria- Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, 4multiple, multiple, Spain

    Background/Purpose The use of biomarkers to predict response to the different drugs available for treating rheumatoid arthritis (RA) is a very desirable goal. However, success…
  • Abstract Number: 2085 • 2014 ACR/ARHP Annual Meeting

    Association of Circulating Mirnas with Spinal Involvement in Patients with Axial Spondyloarthritis

    Klára Prajzlerová1, Markéta Fojtíková1, Šárka Forejtová1, Astrid Jüngel2, Steffen Gay2, Karel Pavelka1, Jiri Vencovsky1, Ladislav Senolt1 and Mária Filková1, 1Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 2Center of Experimental Rheumatology, Zurich University Hospital, Zurich, Switzerland

    Background/Purpose The altered expression of miRNAs and dysregulation of their target genes has been shown to contribute to the development and maintenance of autoimmune diseases.…
  • Abstract Number: 2084 • 2014 ACR/ARHP Annual Meeting

    Are Genetic Markers Associated with Myocardial Infarction in Patients with Early Rheumatoid Arthritis?

    Lisbeth Ärlestig1, Petros Zamout2, Lena Innala3, Eva Freyhult4, Solveig Wållberg Jonsson2 and Solbritt Rantapää-Dahlqvist2, 1Public Health & Clinical Medicine/Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umea, Sweden, 2Public Health & Clinical Medicine/Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umeå, Sweden, 3Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umeå, Sweden, 4Bioinformatics Infrastructure for Life Sciences, Uppsala, Sweden

    Background/Purpose Cardiovascular disease (CVD) are increased in patients with rheumatoid arthritis (RA). Traditional as well as disease related risk factors seem to contribute to the…
  • Abstract Number: 2083 • 2014 ACR/ARHP Annual Meeting

    Evaporative Dry-Eye Disease and Aqueous Deficient Dry-Eye Disease Associated with Fibromyalgia

    William Pachas1, Jack Greiner2,3,4,5 and Paula Oliver2,3,4,6, 1Center for Rheumatology, Osteoporosis and Fibromyalgia, Boston, MA, 2The Schepens Eye Research Institute, Boston, MA, 3Massachusetts Eye and Ear Infirmary, Boston, MA, 4Harvard Medical School, Boston, MA, 5The Boston Ocular Surface Center, Boston, ME, 6The Boston Ocular Surface Center, Boston, MA

    Background/Purpose Fibromyalgia (FM) patients with ocular discomfort often describe symptoms characteristic of dry eye diseases, but frequently do not fulfill criteria diagnostic of Sjögrens syndrome.…
  • Abstract Number: 2082 • 2014 ACR/ARHP Annual Meeting

    Presence of Acrocyanosis in Patients with Joint Hypermobility

    Ayhan Dinc1 and Göksal Keskin2, 1Rheumatology, Patio Clinic, Ankara, Turkey, 2Immunology, Medical School of Ankara, Ankara, Turkey

    Background/Purpose Joint hypermobility is a common but often poorly recognized connective tissue condition with joint laxity in the absence of any hereditary systemic disease. Acrocyanosis…
  • Abstract Number: 2081 • 2014 ACR/ARHP Annual Meeting

    Ehlers-Danlos Hypermobile (EDS-HT) Patients and Postural Instability : Another Clue to Explain Pain and Fatigue ?

    Roland Jaussaud1, Elodie Vlamynck2, Rami Haidar3, Dorothée Lambert4, Violaine Laurant-Noel5 and Amélie Servettaz5, 1Médecine interne, maladies infectieuses, immunologie clinique, CHU de Reims, REIMS, France, 2Cabinet d'Orthopédie, Versailles, France, 3Cabinet d'Orthopédie, Lille, France, 4Médecine interne, maladies infectieuses, Immunologie clinique, CHU Reims, Reims, France, 5Médecine interne, maladies infectieuses, immunologie clinique, Hôpital Robert Debré. CHU de Reims, Reims, France

    Background/Purpose Postural instability was found in several functional disorders including dyslexia, chronic pain and fibromyalgia. Furthermore, the link between vertical heterophoria (VH) and postural control…
  • Abstract Number: 2080 • 2014 ACR/ARHP Annual Meeting

    Carryover Effects in Crossover Design Studies in Fibromyalgia and Other Pain Conditions

    Lynne Pauer1, Birol Emir2, Ed Whalen3, Joseph Scavone4 and Andrew Clair2, 1445 Eastern Point Road, Pfizer Inc, Groton, CT, 2Pfizer Inc, New York, NY, 3Pfizer Inc., New York, NY, 4Pfizer Inc, Groton, CT

    Background/Purpose: Explore carryover effects and their influence on crossover and randomized withdrawal design (RWD) studies.Methods: We examine pregabalin crossover and RWD studies in fibromyalgia (FM),…
  • Abstract Number: 2079 • 2014 ACR/ARHP Annual Meeting

    The Association Between Straight Neck and Fibromyalgia

    Omar-Eloy Muñoz-Monroy1, Laura-Aline Martinez-Martinez2, Manuel Martínez-Lavín3, Blanca-Adela Mota-Mondragón1 and Evalorena Martínez-Hernández1, 1Hospital Central Militar, Mexico City, Mexico, 2Instituto Nacional de Cardiologia, Mexico City, Mexico, 3Chief Rheumatology, Instituto Nacional de Cardiologia, Mexico City, Mexico

    Background/Purpose: It has been suggested that patients with fibromyalgia very often have radiographic straight neck. According to one study, 71% of patients with fibromyalgia lose…
  • Abstract Number: 2078 • 2014 ACR/ARHP Annual Meeting

    A Proposed Simple 3-Variable Index for Identification of Fibromyalgia, Analogous to Classification Criteria for RA and SLE

    Sung-Hoon Park1, Jung-Yoon Choe2, Seong-Kyu Kim3, Hwajeong Lee4 and Theodore Pincus5, 1Internal Medicine, Arthritis and Autoimmunity Research Center, Catholic University of Daegu School of Medicine, Daegu, South Korea, 2Division of Rheumatology, Catholic University of Daegu School of Medicine, Daegu, South Korea, 3Devision of Rheumatology, Department of Internal Medicine, Arthritis & Autoimmunity Research Center, Catholic University of Daegu School of Medicine, Daegu, South Korea, 4Internal medicine, Catholin university of Daegu School of medicine, Daegu, South Korea, 5rheumatology, Rush univeristy medical center, Chiacago, IL

    Background/Purpose : A cumulative index that includes various quantitative data has been useful in developing classification criteria for various rheumatic diseases, including rheumatoid arthritis (RA)1…
  • Abstract Number: 2077 • 2014 ACR/ARHP Annual Meeting

    A New Tender Point on the Plantar Arch in Primary Juvenile Fibromyalgia: A Potential Point to be Considered

    Walter J. Spindler1, Cecilia Santarelli2, Alberto J. Spindler2, Alberto Berman2, Horacio Berman2 and Mirta Santana2, 1Tucuman, Centro Medico Privado de Reumatologia, Tucuman, Argentina, 2Centro Medico Privado de Reumatologia, Tucuman, Argentina

    Background/Purpose Juvenile Primary Fibromyalgia Syndrome (JPFS) is a chronic and complex musculoskeletal disorder that may cause diffuse pain accompanied by defined tender points. Diagnostic dilemmas…
  • Abstract Number: 2076 • 2014 ACR/ARHP Annual Meeting

    Predictive Modeling of a Fibromyalgia Diagnosis: Increasing the Accuracy Using Real World Data

    Birol Emir1, Jack Mardekian1, Elizabeth T. Masters1, Andrew Clair1, Max Kuhn2 and Stuart L. Silverman3, 1Pfizer Inc, New York, NY, 2Pfizer Inc., Groton, CT, 3Cedars-Sinai Medical Center, UCLA Center of Excellence, Los Angeles, CA

    Background/Purpose: The number of symptoms and comorbidities associated with the chronic pain condition of fibromyalgia (FM) complicates its identification and diagnosis. Methods: This retrospective analysis…
  • Abstract Number: 2075 • 2014 ACR/ARHP Annual Meeting

    The Lumbar Spine in Fibromyalgia

    Robert S. Katz1, Alexandra Small2 and Anthony Farkasch3, 1Rush Medical College, Chicago, IL, 2University of Illinois College of Medicine, Chicago, IL, 3Rheumatology Associates, Chicago, IL

    Background/Purpose: Radiographs of the lumbar spine appear normal in fibromyalgia.  However, a previous study (ArthRheum50:134, 2004) found a reduced lordotic curve in the cervical spine…
  • Abstract Number: 2074 • 2014 ACR/ARHP Annual Meeting

    Hypervigilance and FMS

    Robert S. Katz, Rush Medical College, Chicago, IL

    Background/Purpose:   In dangerous environments, hypervigilance conveys  a survival value. A cave dweller who sleeps lightly and startles easily might escape a prowling  bear  while…
  • Abstract Number: 2073 • 2014 ACR/ARHP Annual Meeting

    Is Susceptibility to Fibromyalgia a Trait?

    Robert S. Katz1, Ben J Small2, Lauren Kwan3, Hannah Bond3, Jessica L. Polyak3 and Susan Shott4, 1Rush Medical College, Chicago, IL, 2MacNeal Hospital, Berwyn, IL, 3Rheumatology Associates, Chicago, IL, 4Rush University Medical Center, Chicago, IL

    Background/Purpose: We asked patients, as part of an in-office survey, whether their immediate or extended family members had FMS.  Methods: 211 office patients with either…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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