Abstract Number: 2217 • 2014 ACR/ARHP Annual Meeting
Ultrasonography Analysis of Carotid Parameters in Patients with Idiopathic Inflammatory Myopaties: Correlation with Demographic Profile and Disease Activity
Background/Purpose Subclinical cardiovascular (CV) involvement is frequent in patients with idiopathic inflammatory myositis (IIM). Growing interest exists on the role of markers of subclinical CV…Abstract Number: 2218 • 2014 ACR/ARHP Annual Meeting
Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Dysfunction and Atrophy Can be Prevented By Pharmacological Upregulation of Heat Shock Protein 70 (HSP) in Cultured Murine Myotubes
Background/Purpose: The symmetrical proximal muscle weakness typical of myositis often fails to improve completely with any treatment, due to irreversible muscle fibre degeneration. Although inflammatory…Abstract Number: 2219 • 2014 ACR/ARHP Annual Meeting
Contribution of Tripartite Motif Proteins Modulating Membrane Repair to the Pathogenesis of Autoimmune-Mediated Myositis
Background/Purpose: The idiopathic inflammatory myopathies are a heterogeneous group of diseases that result in autoimmunity toward muscles and lead to tissue destruction, but the pathogenesis…Abstract Number: 2220 • 2014 ACR/ARHP Annual Meeting
Overexpression of Ankyrin Repeat Domain Containing Protein 1 Gene (ANKRD1) in Polymyositis Muscle Biopsies Is Correlated to Hypoxia
Background/Purpose: ANKRD1 codes for ankyrin repeat domain containing protein 1, which belongs to the muscle ankyrin repeat protein family involved in a mechano-signaling pathway that…Abstract Number: 2221 • 2014 ACR/ARHP Annual Meeting
Reduction of Ovarian Reserve in Adult Patients with Dermatomyositis
Background/Purpose: Dermatomyositis (DM) affects female gender during reproductive age, in which ovarian reserve and future fertility are major topics of interest. However, there is no…Abstract Number: 2222 • 2014 ACR/ARHP Annual Meeting
Predictors of Myositis Treatments Received and Associated Treatment Responses in Myovision, a National Myositis Patient Registry
Background/Purpose: Little is known about medications received for myositis and patients’ responses to therapies. We present information on self-reported myositis therapy use and responses from…Abstract Number: 2223 • 2014 ACR/ARHP Annual Meeting
High Prevalence of Hepatitis C Virus Infection in a Japanese Inclusion Body Myositis Cohort
Background/Purpose There have been several case reports of inclusion body myositis (IBM) that appeared after chronic hepatitis C virus (HCV) infection. However, the relationship between…Abstract Number: 2224 • 2014 ACR/ARHP Annual Meeting
Increased Immune Complex Levels in Children with Juvenile Dermatomyositis Are Not Associated with Levels of Von Willebrand Factor Antigen, C4, Duration of Illness, Disease Activity Score, or the Absolute NK Count
Background/Purpose: A potential mechanism for the vasculopathy of Juvenile Dermatomyositis (JDM), the most common pediatric inflammatory myopathy, has been attributed to complement mediated immune complex…Abstract Number: 2225 • 2014 ACR/ARHP Annual Meeting
Does Previous Corticosteroid Treatment Affect the Inflammatory Infiltrate Found in Polymyositis Muscle Biopsies?
Background/Purpose: We conducted this study because there have been no studies evaluating the effect of the use of corticosteroids (CE) on the presence of inflammatory…Abstract Number: 2226 • 2014 ACR/ARHP Annual Meeting
Systemic Treatment for Clinically Amyopathic Dermatomyositis
Background/Purpose: Clinically amyopathic dermatomyositis (CADM) is an important subset and accounts for approximately 20% of patients with dermatomyositis (DM). CADM is characterized by the presence…Abstract Number: 2227 • 2014 ACR/ARHP Annual Meeting
Physical Impairment in Patients with Idiopathic Inflammatory Myopathies Is Predicted By the American College of Rheumatology Functional Status Measure
Background/Purpose The American College of Rheumatology classification criteria of functional status (ACR-FS) in Rheumatoid Arthritis is used as a measure of the consequences of impairment…Abstract Number: 2228 • 2014 ACR/ARHP Annual Meeting
Has MRI an Added Value over Serum Creatine Kinase Measurement in Myositis?
Background/Purpose MRI is widely used to assess inflammation in myositis. Muscle edema on short tau inversion recovery (STIR) sequences is thought to reflect active inflammation.…Abstract Number: 2229 • 2014 ACR/ARHP Annual Meeting
How Often Are Clinically Amyopathic Dermatomyositis Patients Truly Amyopathic?
Background/Purpose: Juvenile dermatomyositis (JDM) is a chronic inflammatory disorder primarily involving the skin and striated muscle. Classic JDM presents with rash, proximal muscle weakness, and…Abstract Number: 2230 • 2014 ACR/ARHP Annual Meeting
Treatment of Symptomatic Knee Osteoarthritis with Oral Salmon Calcitonin: Results from Two Phase 3 Randomized Clinical Trials
Background/Purpose: To evaluate the structure-modifying and symptom efficacy, as well as safety and tolerability of oral salmon calcitonin (sCT) formulated with a 5-CNAC carrier (a…Abstract Number: 2191 • 2014 ACR/ARHP Annual Meeting
Intravenous Sodium Thiosulfate for Treatment of Refractory Calcinosis in Rheumatic Disease
Background/Purpose: Calcinosis, or dystrophic calcification, is a poorly understood, debilitating condition commonly manifested in connective tissue diseases such as scleroderma and polymyositis. Despite treatment of…
ACR Meeting Abstracts