Abstracts Archive - Page 2086 of 2425 - ACR Meeting Abstracts

Abstract Number: 2474 • 2013 ACR/ARHP Annual Meeting
Fat Mass and Resistin: Predictive Factors For Anti-TNF Therapy Response In Ankylosing Spondylitis Patients
Carla G.S. Saad¹, Andressa Silva Abreu¹, Ana Cristina Medeiros Ribeiro¹, Julio C. B. Moraes², Luiz A. Perandini¹, Thalita Dassouki³, Rosa M. R. Pereira⁴, Eloisa Bonfa⁵ and Ana Lucia S. Pinto¹, ¹Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ⁴Reumatologia, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, ⁵Rheumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: The adipose tissue immune properties and pharmacokinetic consequences can contribute to the pathogenesis of inflammatory conditions. The hole of fat tissue in active Ankylosing…
Abstract Number: 2475 • 2013 ACR/ARHP Annual Meeting
Relationship Between Extra-Articular Manifestations and Disease Activity In Patients Diagnosed With New-Onset Spondyloarthropathy In a Cohort In Spain
César Antonio Egües Dubuc¹, Maria Martin Martinez², Joaquin Belzunegui Otano¹, Miren Uriarte Ecenarro¹, Juan Mulero³, Eugenio de Miguel⁴, Santiago Muñoz⁵, Pedro Zarco⁶, Eduardo Collantes⁷, Sabina Perez Vicente² and Milena Gobbo², ¹Rheumatology, Donostia University Hospital, San Sebastián, Spain, ²Research Unit, Spanish Society of Rheumatology., Madrid, Spain, ³Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Spain, ⁴Rheumatology, University Hospital La Paz - IdiPaz, Madrid, Spain, ⁵Rheumatology, Hospital Infanta Sofia, Madrid, Spain, ⁶Rheumatology Service, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain, ⁷Rheumatology, Hospital Reina Sofia, Cordoba, Spain
Background/Purpose : The Spondyloarthropathy (SpA) that affect in many aspects of life of the patients, either for their musculoskeletal or extra-articular manifestations (EAM). EAM vary…
Abstract Number: 2476 • 2013 ACR/ARHP Annual Meeting
Periodontal Disease Is Not Associated With Ankylosing Spondylitis and TNF-Alpha Blockers Usage In Korea
Sung Hae Chang^1,2, Jung Tae Lee³, Byoung Youg Choi⁴, Hyon Joung Cho⁵, Jong Jin Yoo⁶, Hye Jin Oh⁷, Eun Ha Kang⁴, Yeong Wook Song^2,8, Hyo Jung Lee⁹ and Yun Jong Lee^2,10, ¹Internal Medicine Rheumatology, Seoul National University Bundang Hospital, Seongnam-si, South Korea, ²Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ³Periodontology,Dentistry, Seoul National University Bundang Hospital, Seongnam-si, South Korea, ⁴Internal Medicine, Rheumatology, Seoul National University Bundang Hospital, Seongnam-si, South Korea, ⁵Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, South Korea, ⁶Internal Medicine, Armed Forces Capital Hospital Seongnam Republic of Korea, Seongnam si, South Korea, ⁷Internal Medicine, Rheumatology, Seoul National University Hospital, Seoul, South Korea, ⁸Internal Medicine,Rheumatology, Seoul National University Hospital, Seoul, South Korea, ⁹Periodontology, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam-si, South Korea, ¹⁰Division of Rheumatology, Department of Internal Medicine,Seoul National University Bundang Hospital, Seongnam, South Korea
Background/Purpose: Periodontal disease (PD) is a chronic inflammatory disease, which has been reported to be associated with rheumatoid arthritis (RA). But, a few studies on…
Abstract Number: 2477 • 2013 ACR/ARHP Annual Meeting
Impact Of Stressful Life Events On Disease Activity In Spondyloarthritis: Results Of The Coenv-2 Prospective Cohort Study
Guanguan Luo¹, Pierre Yves Boelle¹, Clément Turbelin¹, Roula Said Nahal², Nadine Zeboulon³, Maria-Antonietta d'Agostino⁴, Solen Kerneis¹, Thomas Hanslik^1,5 and Maxime A. Breban^4,6, ¹Epidemiology-UMR S 707, Faculté de Médecine Pierre et Marie Curie, Paris, France, ²Service de Rhumatologie, Hopital Ambroise Pare, Boulogne-Billancourt, France, ³Rheumatology, Ambroise Paré Hospital, Boulogne-Billancourt, France, ⁴Rheumatology, Ambroise Paré Hospital, and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁵Internal Medicine, Ambroise Paré Hospital, and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁶Immunology, NSERM U1016 - CNRS (UMR 8104), Montigny le Bretonneux, France
Background/Purpose: The relative contribution of environmental factors to triggering and/or progression of spondyloarthritis (SpA) remains poorly characterized. A link between disease activity and stressful life…
Abstract Number: 2479 • 2013 ACR/ARHP Annual Meeting
Adalimumab Significantly Reduces Inflammation In Active Ankylosing Spondylitis: An Ultrasound Study
Zaiying Hu¹, Manlong Xu², Zetao Liao³, Zhiming Lin⁴ and Jieruo Gu⁵, ¹Rheumatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²THIRD AFFILIATED HOSPITAL OF SUN YAT-SEN UNIVERSIT, Guangzho, China, ³Rheumatology, The Affiliated Third Hospital of Sun Yat-san University, Rheumatology, Guangzhou, China, ⁴Rheumatology, third affiliated hospital of Sun Yat-sen Universtiy, Guangzhou, China, ⁵Medicine, Third Affiliated Hospital of Sun Yat-sen University, GuangZhou, China
Background/Purpose: To evaluate the feasibility of using power Doppler ultrasound (PDUS) to detect inflammation in sacroiliac joints and entheses after adalimumab (a TNF-alpha antagonist) treatment…
Abstract Number: 2480 • 2013 ACR/ARHP Annual Meeting
Predicting Progression Of Non-Radiographic Axial Spondyloarthritis
Nigil Haroon^1,2,3, Lianne S. Gensler⁴, Dinny Wallis⁵, Ammepa Anton¹, Grace Yoon⁶ and Robert D. Inman⁷, ¹Rheumatology, University Health Network, Toronto, ON, Canada, ²Medicine, Rheumatology, University of Toronto, Toronto, ON, Canada, ³Toronto Western Research Institute, Toronto, ON, Canada, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁵Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁶Medicine/Rheumatology, UCSF, San Franciscao, CA, ⁷Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: A proportion of patients with non-radiographic axial spondyloarthritis (NR-AxSpA) progress to AS but the predictors of progression have not been well established. We studied…
Abstract Number: 2481 • 2013 ACR/ARHP Annual Meeting
External Validation Of The Spondyloarthritis Radiography Online Reference Module For Training Readers To Score The Modified Stoke Ankylosing Spondylitis Score
Praveena Chiowchanwisawakit¹, Susanne Juhl Pedersen² and Walter P. Maksymowych³, ¹Mahidol University, Bangkok, Thailand, ²Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ³Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) is commonly used to assess disease severity and progression in patients with AS; however, the reliability…
Abstract Number: 2482 • 2013 ACR/ARHP Annual Meeting
Which Contextual Factors Have An Important Influence On Work Outcome In Patients With Ankylosing Spondylitis. A Systematic Literature Review
Jose Dionisio Castillo-Ortiz^1,2, Carmen Stolwijk³ and Annelies Boonen¹, ¹Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ²Unidad de Investigacion en Enfermedades Cronico-Degenerativas, Guadalajara, Mexico, ³School for Public Health and Primary Care (CAPHRI), Maastricht University, Maastricht, Netherlands
Background/Purpose: It is increasingly recognized that contextual factors (either environmental or personal) play a role in the magnitude in which the disease influences work participation.…
Abstract Number: 2483 • 2013 ACR/ARHP Annual Meeting
Periarticular Bone Gain In Early Psoriatic Arthritis But Not In Rheumatoid Arthritis Following Anti-Rheumatic Treatment As Measured By Digital X-Ray Radiogrammetry
Agnes Szentpetery¹, Muhammad Haroon², Phil Gallagher³, Eric J. Heffernan⁴ and Oliver FitzGerald², ¹Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ²Department of Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ³Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ⁴Radiology, St. Vincent's University Hospital, Dublin, Ireland
Background/Purpose: Hand bone loss is an early feature in both RA and PsA, but there is less data available on periarticular bone gain, in particular…
Abstract Number: 2484 • 2013 ACR/ARHP Annual Meeting
Immunogenicity Of TNFα Blockers In Patients With Psoriatic Arthritis
Michael Zisapel Zisapel¹, Noa Madar-Balakirsi², Hagit Padova³, Irena Wigler⁴, Daphna Paran⁵, Uri Arad⁴, Dan Caspi⁶ and Ori Elkayam⁷, ¹Rheumatology, Tel Aviv Medical Centet, Tel Aviv, Israel, ²Rheumatology, Tel Aviv Medical Center, Tel Aviv, Israel, ³Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁴Department of Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁵Rheumatology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv university, Tel Aviv, Israel, ⁶Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel- Aviv, Israel
Background/Purpose: TNFα blockers have been shown to produce immunogenecity in patients with rheumatoid arthritis, spondyloarthrritis and inflammatory bowel diseases. Data on the induction of anti-drug…
Abstract Number: 2485 • 2013 ACR/ARHP Annual Meeting
High Incidence Of Disease Recurrence After Discontinuation Of Disease Modifying Anti-Rheumatic Drug Treatment In Patients With Psoriatic Arthritis In Remission
Elizabeth Araujo¹, Stephanie Finzel¹, Dominik A. Schreiber², Matthias Englbrecht¹, Axel J. Hueber³, Francesca Faustini³, Juergen Rech³ and Georg Schett¹, ¹Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²University of Erlangen-Nuremberg, Erlangen, Germany, ³Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: In the era of modern anti-rheumatic therapy, it is now possible to contemplate the idea of clinical remission in patients with psoriatic arthritis (PsA).…
Abstract Number: 2486 • 2013 ACR/ARHP Annual Meeting
Clinical Performance Of 4 Methods For Detecting Latent Tuberculosis Infection (LTbI) In Patients With Active Chronic Inflammatory Arthritis Taking TNFα Blockers
Carina M F Gomes¹, Maria Teresa Terreri², Maria Isabel Pinto³, Karen Oseki³, Fernanda Spina⁴ and Marcelo M. Pinheiro⁵, ¹Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, ²Pediatrics, Universidade Federal de São Paulo / UNIFESP, Sao Paulo, Brazil, ³Pediatrics, Universidade Federal de São Paulo, Sao Paulo, Brazil, ⁴Rheumatology Division, Universidade Federal de São Paulo Unifesp/EPM, Brazil, Universidade Federal de São Paulo, Sao Paulo, Brazil, ⁵Brazilian Registry of Spondyloarthritis, São Paulo, Brazil
Background/Purpose: About 5% of the Brazilian population has some chronic inflammatory arthropathy (CIA), including rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PA) and juvenile…
Abstract Number: 2487 • 2013 ACR/ARHP Annual Meeting
Role Of IL-33 In The Development Of Premature Atherosclerosis In Psoriatic Arthritis Patients
Priscilla Ching-han Wong¹, Qing Shang², Cheuk-Man Yu² and Lai Shan Tam², ¹Medicine and Therapeutics, Prince of Wales hospital, New Territories, Hong Kong, ²Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Interleukin 33 (IL-33) is a newly identified member of the IL-1 cytokine family. It involves in T-cell mediated immune responses through the activation of…
Abstract Number: 2488 • 2013 ACR/ARHP Annual Meeting
Elevated Serum Anti-Flagellin Antibodies Implicate Subclinical Bowel Inflammation in Ankylosing Spondylitis
Dinny Wallis¹, Arundip Asaduzzaman¹, Michael H. Weisman², Nigil Haroon¹, Ammepa Anton³, Dermot P. B. McGovern⁴, Stephan R. Targan⁵ and Robert D. Inman⁶, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²Rheumatology, Cedars-Sinai Med Ctr, Los Angeles, CA, ³Rheumatology, University Health Network, Toronto, ON, Canada, ⁴Department of Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁶Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Elevated serum anti-flagellin antibodies implicate subclinical bowel inflammation in ankylosing spondylitisBackground/Purpose: Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) share genetic and clinical features. IBD…
Abstract Number: 2489 • 2013 ACR/ARHP Annual Meeting
Spondyloarthritis-Associated Polymorphisms Of ERAP1 Are Correlated With Gene Expression, Protein Level and Enzymatic Activity Of The Amino-Peptidase
Félicie Costantino¹, Alice Talpin², Irini Evnouchidou³, Amir Kadi², Roula Said-Nahal⁴, Ariane Leboime⁵, Nelly Bonilla⁶, Franck Letourneur⁶, Tifenn Leturcq², Zeyna Ka², Peter van Endert³, Henri-Jean Garchon^2,7, Gilles Chiocchia^8,9 and Maxime A. Breban^2,7, ¹INSERM U987, Faculté des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France, ²Institut Cochin - Université Paris Descartes - INSERM U1016 - CNRS (UMR 8104), Paris, France, ³INSERM U1013 - Université Paris Descartes - Sorbonne Paris Cité, Paris, France, ⁴Rheumatology Division, Ambroise Paré Hospital (AP-HP), and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁵Rheumatology Division, Ambroise-Paré Hospital AP-HP, Boulogne-Billancourt, France, ⁶INSERM U1016, Cochin Institute, Paris, France, ⁷Ambroise Paré Hospital (AP-HP), and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁸Versailles Saint Quentin en Yvelines University, INSERM U987, UFR des Sciences de la Santé, Montigny-le-Bretonneux, France, ⁹Université Versailles-Saint Quentin, Montigny le Bretonneux, France
Background/Purpose: Endoplasmic reticulum aminopeptidase 1 (ERAP1) exerts a central role in antigen presentation making it an attractive candidate gene for inflammatory diseases. Several polymorphisms in…

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