ACR Meeting Abstracts

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  • Abstract Number: 2501 • 2013 ACR/ARHP Annual Meeting

    Validation Of Gene Expression Biomarkers Of Psoriatic Arthritis

    Fatima Abji1, Remy Pollock1, Fawnda Pellett2, Kun Liang3, Vinod Chandran2 and Dafna D. Gladman2, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada

    Background/Purpose: Psoriatic arthritis (PsA) is a seronegative immune mediated arthritis that develops in about a third of patients with cutaneous psoriasis (PsC). The cellular pathways…
  • Abstract Number: 2502 • 2013 ACR/ARHP Annual Meeting

    Contributions Of Skin and Joint Manifestations To The Parent-Of-Origin Effect In Psoriatic Disease

    Remy Pollock1, Arane Thavaneswaran2, Vinod Chandran3, Art Petronis4, Al Amin P. Rahman5 and Dafna D. Gladman3, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4The Krembil Family Epigenetics Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada, 5Medicine, Memorial University, St Johns, NE, Canada

    Background/Purpose: Excessive paternal transmission has been previously documented in psoriatic disease. Our objective is to delineate the differential contributions of skin and joint manifestations to…
  • Abstract Number: 2503 • 2013 ACR/ARHP Annual Meeting

    IL-17+ CD8+ T Cells Are Enriched In The Joints Of Patients With Psoriatic Arthritis and Correlate With Markers Of Disease Activity and Joint Damage Progression

    Bina Menon1,2, Nicola J. Gullick3, Hayley G. Evans4, Gina J. Walter4, Megha Rajasekhar4, Toby Garrood2, Leonie S. Taams4 and Bruce W. Kirkham2, 1Centre for Cellular and Molecular Biology of Inflammation, King's College London, London, United Kingdom, 2Rheumatology, Guy's and St. Thomas' Foundation Hospital NHS Trust, London, United Kingdom, 3Rheumatology, King's College Hospital Foundation NHS Trust, London, United Kingdom, 4Centre for Molecular and Cellular Biology of Inflammation, King's College London, London, United Kingdom

    Background/Purpose: Psoriatic arthritis (PsA) and rheumatoid arthritis (RA) have clear differences in clinical, radiological and genetic features, suggesting that the immunopathology of the conditions may…
  • Abstract Number: 2504 • 2013 ACR/ARHP Annual Meeting

    Male Children With Higher SLE Disease Activity In An US Cohort

    Lakshmi N. Moorthy1, Elizabeth Roy2, Margaret Peterson3, Afton L. Hassett4, Alexa B. Adams5, Laura V. Barinstein6, Elizabeth C. Chalom7, Karen Onel8, Linda Ray9, Jorge Lopez-Benitez10, Kathleen A. Haines11, Philip Hashkes12, Daniel J. Kingsbury13, Victoria Cartwright14, Nora G. Singer15, Ingrid Tomanova-Soltys16, Andreas Reiff17, Sandy D. Hong18 and Thomas J. A. Lehman19, 1Pediatric Rheumatology, Robert Wood Johnson Medical School-Rutgers University, New Brunswick, NJ, 2RWJMS-UMDNJ, New Brunswick, NJ, 3Hospital for Special Surgery, New York, NY, 4Anesthesiology, University of Michigan, Ann Arbor, MI, 5Pediatric Rheumatology, Hospital for Special Surgery, New York, NY, 6Pediatric Rheumatology, Mount Sinai Med Ctr, New York, NY, 7Pediatrics, St. Barnabas Medical Center, Livingston, NJ, 8Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, 9Pediatric Rheumatology, University of Mississippi Medical Center, Jackson, MS, 10Pediatric Rheumatology Program Centro Medico La Costa, Asuncion, Paraguay, 11Department of Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 12Pediatric Rheumatology, Shaare Zedek Medical Center, Jerusalem, Israel, 13Randall Children's Hospital at Legacy Emanuel, Portland, OR, 14Legacy Emanuel Children's Hospital, Portland, OR, 15Medicine, Division of Rheumatology, MetroHealth Medical Center, Cleveland, OH, 16Winthrop University Hospital, Mineola, NY, 17Division of Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, 18Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, 19Chief Div Ped Rheum PTD, Hospital for Special Surgery, New York, NY

    Background/Purpose: Although systemic lupus erythematosus (SLE) is more common in females, males tend to have more severe disease. We compared age at SLE diagnosis, duration,…
  • Abstract Number: 2505 • 2013 ACR/ARHP Annual Meeting

    Higher Disease Damage Among African Americans With Familial Versus Sporadic Systemic Lupus Erythematosus

    April Barnado1, Lee Wheless2, Stephanie Slan1, Gary S. Gilkeson1 and Diane L. Kamen1, 1Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, 2Public Health Sciences, Medical University of South Carolina, Charleston, SC

    Background/Purpose: Studies in predominantly Caucasian cohorts have found no significant clinical or serologic differences in systemic lupus erythematosus (SLE) patients with a family history of…
  • Abstract Number: 2506 • 2013 ACR/ARHP Annual Meeting

    Systemic LUPUS Erythematosus Patients Presenting With Immune Thrombocytopenia and The Association Between Two Diseases

    Omer Nuri Pamuk1, Gulsum Emel Pamuk2 and Mehmet Sevki Uyanik2, 1Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, 2Hematology, Trakya University Medical Faculty, Edirne, Turkey

    Background/Purpose: We evaluated the features of our systemic lupus erythematosus (SLE) patients who presented with immune thrombocytopenia (ITP) and compared them to other SLE patients.…
  • Abstract Number: 2507 • 2013 ACR/ARHP Annual Meeting

    What Is The Risk Of Having a Total Hip Or Knee Replacement for Patients With Lupus?

    Sandeep Mukherjee1, David Culliford2, Nigel K. Arden3 and Christopher J. Edwards1, 1NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, 2Faculty of Medicine, University of Southampton, Southampton, United Kingdom, 3NDORMS; MRC Lifecourse Epidemiology Unit, Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom

    Background/Purpose: Individuals with systemic lupus erythematosus (SLE) frequently have arthralgia, but joint damage leading to surgery is thought to be less common. In addition to…
  • Abstract Number: 2508 • 2013 ACR/ARHP Annual Meeting

    Clinical and Serological Discordance In The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) Cohort

    Murray B. Urowitz1, Dafna D. Gladman1, Nicole Anderson1 and Systemic Lupus Erythematosus International Collaborating Clinics SLICC2, 1Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Anti-DNA antibodies and serum complement levels are considered important biomarkers for disease activity in SLE.  Despite this many SLE patients present serologically active (positive…
  • Abstract Number: 2509 • 2013 ACR/ARHP Annual Meeting

    Long Term Natural History Of Asymptomatic Avascular Necrosis In a Cohort Of Patients With Systemic Lupus Erythematosus Treated With Corticosteroids

    Eileen J. Lydon1 and H. Michael Belmont2, 1Rheumatology, NYU Hospital for Joint Diseases, New York, NY, 2NYU School of Medicine, New York, NY

    Background/Purpose: Avascular necrosis (AVN) is cellular death of bone components due to interruption of the blood supply resulting in area of ischemic necrosis but may…
  • Abstract Number: 2510 • 2013 ACR/ARHP Annual Meeting

    The Epidemiology Of Systemic LUPUS Erythematosus and Clinical Features Of Patients At A Single Center In Northwestern Turkey

    Omer Nuri Pamuk1, Salim Dönmez2, Gokce Busra Calayir3 and Cigdem Mengus4, 1Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, 2Rheumatology, Yüzüncü Yıl University Medical Faculty, Edirne, Turkey, 3Rheumatology, Trakya University Medical Faculty, Edirne, Turkey, 4Internal Medicine, Trakya University Medical Faculty, Edirne, Turkey

    Background/Purpose: We evaluated  the clinical features, treatment modalities, treatment responses and prognosis of patients diagnosed with systemic lupus erythematosus (SLE). We also estimated the prevalence…
  • Abstract Number: 2511 • 2013 ACR/ARHP Annual Meeting

    Multicenter Validation Of The Lupus Activity Scoring Tool (LAST) As Compared To The Selena Sledai (SS) Modification

    Majed M. Khraishi1, Rana Aslanov2, Sanjay Dixit3, Krista Fudge4, Vandana Ahluwalia5 and Sarah Khraishi6, 1Nexus Clinical Research, St John's, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, 3McMaster University, Hamilton, ON, Canada, 4Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada, 5Past President, Ontario Rheumatology Association, Brampton, ON, Canada, 6Nexus Clinical Research, Memorial University of Newfoundland, St.John's, NF, Canada

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic immune modulated disease with variable clinical manifestations. New advances in the management of SLE mandated closer monitoring…
  • Abstract Number: 2473 • 2013 ACR/ARHP Annual Meeting

    Comparison Of The Two Subtypes Of Axial Spondyloarthritis Patients Fulfilling The Imaging Arm Based On Radiographic and MRI Findings

    Dilek Solmaz, Servet Akar, Ismail Sari, Pinar Cetin, Fatos Onen and Nurullah Akkoc, Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey

    Background/Purpose: New Axial Spondyloarthritis Classification Criteria  include an imaging arm and a clinical arm. The imaging arm includes radiographic ax-SpA patients who have radiographic sacroilitis…
  • Abstract Number: 2478 • 2013 ACR/ARHP Annual Meeting

    Clinical Characteristics Of Patients With Early Spondyloarthritis. Results From a Specialized Consultation In a Clinical Hospital

    Juan Jose Aznar Sánchez, Eugenio Chamizo Carmona, Adela Gallego Flores, Raul Veroz Gonzalez and Tamara Libertad Rodriguez Araya, Rheumatology, Hospital de Mérida, Mérida, Spain

    Background/Purpose: The classification criteria for spondyloarthritis (SpA) intend to identify patients with this disease from the initial stages.  The nonspecific characteristics,  symptoms, signs, and additional…
  • Abstract Number: 2471 • 2013 ACR/ARHP Annual Meeting

    Prevalence Of Inflammatory Back Pain In Psoriatic Arthritis: The Prepare Study

    Majed Khraishi1, Dafna D. Gladman2, Javier Coindreau3, Lotus Mallbris3, Annette Szumski4, Eustratios Bananis4 and Heather Jones3, 1Nexus Clinical Research, St John's, NF, Canada, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Pfizer Inc., Collegeville, PA, 4Specialty Care, Pfizer Inc., Collegeville, PA

    Background/Purpose: Up to 30% of patients with psoriasis (Ps) may develop psoriatic arthritis (PsA); ranging from mild and non-destructive disease to severe and erosive arthritis.1…
  • Abstract Number: 2472 • 2013 ACR/ARHP Annual Meeting

    Disease Burden Is Similar Between Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis and Independent Of Gender Influences

    Salih Ozgocmen1, Erkan Kilic2, Gamze Kilic2 and Ozgur Akgul2, 1Division of Rheumatology, Dept.PRM, Erciyes University, Faculty of Medicine, Kayseri, Turkey, 2Division of Rheumatology, Dept. PRM, Erciyes University, Faculty of Medicine, Kayseri, Turkey

    Disease Burden is Similar between Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis and Independent of Gender Influences Background/Purpose: Axial spondyloarthritis (SpA) covers both ankylosing spondylitis (AS)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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