Abstracts Archive - Page 2074 of 2425 - ACR Meeting Abstracts

Abstract Number: 2659 • 2013 ACR/ARHP Annual Meeting
Antibodies To Citrullinated Enolase, Fibrinogen, and Vimentin Are Associated With Markers Of Endothelial Dysfunction In First-Degree Relatives Of Patients With Rheumatoid Arthritis: The Studies Of The Etiology Of Rheumatoid Arthritis
Jan M. Hughes-Austin¹, Kendra A. Young², Kevin D. Deane³, Michael H. Weisman⁴, Jane H. Buckner⁵, Ted R. Mikuls⁶, James R. O'Dell⁷, Richard M. Keating⁸, Peter K. Gregersen⁹, Jeremy Sokolove¹⁰, William H. Robinson¹¹, V. Michael Holers¹² and Jill M. Norris², ¹Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, ²Epidemiology, Colorado School of Public Health, Aurora, CO, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Rheumatology, Cedars-Sinai Med Ctr, Los Angeles, CA, ⁵Benaroya Research Institute at Virginia Mason, Seattle, WA, ⁶Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁷Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ⁸Rheumatology Section, The University of Chicago, Chicago, IL, ⁹Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, ¹⁰VA Palo Alto Healthcare System and Stanford University, Palo Alto, CA, ¹¹Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ¹²Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Among rheumatoid arthritis (RA) patients, antibodies to citrullinated protein antigens (ACPA) have been detected in atherosclerotic plaques. In particular, antibodies to citrullinated fibrinogen (cit-fib)…
Abstract Number: 2660 • 2013 ACR/ARHP Annual Meeting
Omega-3 Supplement Use Is Associated With a Reduced Risk Of Anti-Cyclic Citrullinated Protein Positivity In a Population Without Rheumatoid Arthritis, But At Risk For Future Disease
Ryan W. Gan¹, Kendra A. Young¹, Gary O. Zerbe², M. Kristen Demoruelle³, Michael H. Weisman⁴, Jane H. Buckner⁵, Peter K. Gregersen⁶, Ted R. Mikuls⁷, James R. O'Dell⁸, Richard M. Keating⁹, Michael J. Clare-Salzler¹⁰, Kevin D. Deane³, V. Michael Holers¹¹ and Jill M. Norris¹, ¹Epidemiology, Colorado School of Public Health, Aurora, CO, ²Biostatistics and Informatics, Colorado School of Public Health / University of Colorado Anschutz Medical Campus, Aurora, CO, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Benaroya Research Institute at Virginia Mason, Seattle, WA, ⁶Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, ⁷Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁸Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ⁹Rheumatology Section, The University of Chicago, Chicago, IL, ¹⁰Experimental Pathology, University of Florida, College of Medicine, Gainesville, FL, ¹¹Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Rheumatoid arthritis (RA) is characterized by systemic inflammation and circulating autoantibodies, which can be present in serum years prior to RA diagnosis and can…
Abstract Number: 2661 • 2013 ACR/ARHP Annual Meeting
Physical Activity, Adiposity, and The Risk Of Gout In Women: The Nurses Health Study
Hyon Choi^1,2,3, Lindsay C Burns^4,5, Yuqing Zhang⁶, Sharan Rai¹ and Gary Curhan⁷, ¹Arthritis Research Centre of Canada, Richmond, BC, Canada, ²Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Research, Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁵Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada, ⁶Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁷German Research Center for Environmental Health, Harvard Medical School, Boston, MA
Background/Purpose: There is a remarkable, increasing disease burden of gout and its associated cardiovascular (CV)-metabolic comorbidities in the US. While the benefits of physical exercise…
Abstract Number: 2662 • 2013 ACR/ARHP Annual Meeting
Quality Of Care Predicts Disease Outcomes Among Patients With Systemic Lupus Erythematosus
Jinoos Yazdany¹, Laura Trupin¹, Patricia P. Katz¹, Gabriela Schmajuk¹ and Edward H. Yelin², ¹Medicine, University of California, San Francisco, San Francisco, CA, ²Medicine, UC San Francisco, San Francisco, CA
Background/Purpose: Although measures to assess quality of care in systemic lupus erythematosus (SLE) are available, their relationship to long-term disease outcomes is unknown. Using a…
Abstract Number: 2663 • 2013 ACR/ARHP Annual Meeting
Moving Towards Personalized Healthcare: A Patient Reported Outcome Based Algorithm Can Aid Rheumatologists and Patients In Monitoring Rheumatoid Arthritis In Daily Clinical Practice
Jos Hendrikx¹, Jaap Fransen², Alessandro Toniolo³ and Piet L.C.M. van Riel⁴, ¹Rheumatology (470), Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Pfizer Pharmaceuticals, Rome, Italy, ⁴Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Several Patient Reported Outcome (PRO)-based instruments to measure disease activity in Rheumatoid Arthritis (RA) exist, though an evidence base for their use in monitoring…
Abstract Number: 2664 • 2013 ACR/ARHP Annual Meeting
Evaluation Of Osteoporosis Medication Starts In Patients Based On T-Score and FRAX® Absolute Fracture Risk Model In a Large Health Care System
Robert A. Overman^1,2 and Chad L. Deal³, ¹Eshelman School of Pharmacy - Division of Pharmaceutical Policy and Outcomes, University of North Carolina, Chapel Hill, NC, ²Rheumatology, Cleveland Clinic, Cleveland, OH, ³Dept of Rheum & Imm Dis /A 50, Cleveland Clinic, Cleveland, OH
Background/Purpose: The National Osteoporosis Foundation (NOF) 2008 guidelines recommend treatment for postmenopausal women (PMW) and men ≥ 50 if the T-score is ≤-2.5 at the…
Abstract Number: 2665 • 2013 ACR/ARHP Annual Meeting
Efficiency Gains For Rheumatology Consultation From An Electronic Referral System In a Safety Net Health System
Meghan M. Scheibe¹, John B. Imboden², Gabriela Schmajuk³, Mary Margaretten⁴, Jonathan D. Graf⁵, Alice Chen³, Edward H. Yelin⁶ and Jinoos Yazdany³, ¹Internal Medicine, California Pacific Medical Center, San Francisco, CA, ²Department of Medicine, Division of Rheumatology, UCSF, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA, ⁴Rheumatology, University of California, San Francisco, San Francisco, CA, ⁵Div Of Rheumatology, University of California, San Francisco, San Francisco, CA, ⁶Arthritis Research Group, University of California, San Francisco, San Francisco, CA
Background/Purpose: Rheumatology care is a scarce resource in some settings. Health information technology holds promise in increasing the quality and efficiency of rheumatology referrals, but…
Abstract Number: 2666 • 2013 ACR/ARHP Annual Meeting
Implementing a Personalized Health Plan To Improve Therapeutic Outcomes In Veterans With Gout
Astrud Lorraine Leyva¹, Una E. Makris² and Salahuddin Kazi³, ¹Division of Rheumatic Diseases, UT Southwestern Medical Center, Dallas, TX, ²Rheumatology, UT Southwestern Medical Center, VA Medical Center, Dallas, TX, ³Internal Medicine/Rheumatology, UT Southwestern Medical Center, Dallas, TX
Background: Gout is a chronic crystal-induced arthritis that predominantly occurs among men with rising prevalence with advancing age. Patients with uncontrolled gout present with recurrent…
Abstract Number: 2667 • 2013 ACR/ARHP Annual Meeting
Fast-Track Pathway In Giant Cell Arteritis: A Cost-Effectivenss Analysis
Katerina Achilleos¹, Pravin Patil¹, Win Win Maw¹, Laura Bown², David Halsall², Charles Dobson², Christian Dejaco³, Frances Borg¹, Sunil Gupta⁴ and Bhaskar Dasgupta¹, ¹Rheumatology, Southend University Hospital, Westcliff-on-sea, United Kingdom, ²Department Of Health, National Health Service England, Leeds, United Kingdom, ³Rheumatology and Immunology, Medical University Graz, Graz, Austria, ⁴Castlepoint and Rochford, Clinical Commissioning Group, Southend-on-sea, United Kingdom
Background/Purpose: With incidence of 2.2 per 10,000 patient years, it is estimated that 12,000 new cases of Giant Cell Arteritis (GCA) are diagnosed every…
Abstract Number: 2668 • 2013 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Dose Ranging Study Comparing FX006, An Intra-Articular (IA) Sustained-Release Formulation Of Triamcinolone Acetonide (TCA), To An Approved Injectable Suspension Of TCA In Patients With Osteoarthritis (OA) Of The Knee
Neil Bodick¹, Joelle Lufkin¹, Christina Willwerth¹, Pierre Lachance², Gregory Jasey³, Anil Gupta⁴, Anthony Chris⁵, Marc Russo⁶, Michael O'Mahony⁷, Sam Henein⁸, Louise Murdoch⁹, Ferdinandus de Looze¹⁰, David Hunter¹¹ and Michael Clayman¹, ¹Flexion Therapeutics, Burlington, MA, ²Clinique St-Louis (Recherche) Inc, Quebec, QC, Canada, ³North Walkerville Orthopaedic Associates, Windsor, ON, Canada, ⁴Anil K. Gupta Medicine Professional Corporation, Toronto, ON, Canada, ⁵Aim Health Group, Waterloo, ON, Canada, ⁶Hunter Clinical Research, Broadmeadow, Australia, ⁷London Road Diagnostic Clinic and Medical Centre, Sarnia, ON, Canada, ⁸SKDS Research Inc., Newmarket, ON, Canada, ⁹Emeritus Research, Malvern East, Australia, ¹⁰AusTrials Pty Limited, Sherwood, Australia, ¹¹Royal North Shore Hospital, St. Leonards, Australia
Background/Purpose: FX006 is a novel sustained-release formulation of TCA in poly(lactic-co-glycolic) acid microspheres intended to maintain therapeutic concentrations in the joint up to 3 months…
Abstract Number: 2669 • 2013 ACR/ARHP Annual Meeting
Treatment Of Knee Osteoarthritis Patients With Strontium Ranelate Reduces The Loss Of Cartilage Volume and Bone Marrow Lesions As Assessed By Magnetic Resonance Imaging: Data From The Phase III Strontium Ranelate Efficacy In Knee Osteoarthrtis Trial
Johanne Martel-Pelletier¹, Camille Roubille¹, Jean-Pierre Raynauld¹, François Abram², Marc Dorais³, Philippe Delorme¹ and Jean-Pierre Pelletier¹, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ³StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada
Background/Purpose: This study aimed to evaluate in a subpopulation of osteoarthritis (OA) patients from the SEKOIA Phase III trial the disease-modifying (DMOAD) effect of strontium…
Abstract Number: 2670 • 2013 ACR/ARHP Annual Meeting
Does Change In Femorotibial Cartilage Thickness Differ Between Acutely Anterior-Cruciate Ligament Injured Knees Treated With and Without Reconstructive Surgery
Wolfgang Wirth¹, Felix Eckstein¹, Martin Hudelmaier², Stefan Lohmander³ and Richard Frobell⁴, ¹Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ²Paracelsus Medical University, Salzburg, Austria, ³Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ⁴Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: An ACL tear is a serious knee injury, involving chronic alterations in joint biomechanics. The risk of developing knee OA after an ACL tear…
Abstract Number: 2671 • 2013 ACR/ARHP Annual Meeting
The Relationship Between Toe-Out Angle During Walking and Risk Of Medial Knee Osteoarthritis Incidence: The Multicenter Osteoarthritis Study
K. Douglas Gross¹, Yuqing Zhang¹, Emily K. Quinn², Michael C. Nevitt³, Neil A. Segal⁴, Cora E. Lewis⁵ and David T. Felson¹, ¹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Unit, Boston University, Boston, MA, ³Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁴Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁵Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL
Background/Purpose: A previous study suggests a linear relationship between increased toe-out angle during walking and reduced risk of medial knee OA progression. Yet, gait lab…
Abstract Number: 2672 • 2013 ACR/ARHP Annual Meeting
Associations Between Popliteal Artery Wall Thickness and Knee Structure In Adults Without Clinical Knee Disease: A Prospective Cohort Study
Yuanyuan Wang¹, Diaz Novera¹, Anita Wluka², Jessica Fairley¹, Graham Giles³, Richard O'Sullivan⁴, Andrew Teichtahl⁵ and Flavia Cicuttini², ¹Monash University, Melbourne, Australia, ²Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, ³University of Melbourne, Melbourne, Australia, ⁴Epworth Hospital, Melbourne, Australia, ⁵Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: There is evidence for a vascular contribution to the pathogenesis of osteoarthritis. The aim of this study was to examine the association between popliteal…
Abstract Number: 2673 • 2013 ACR/ARHP Annual Meeting
Mortality In Clinically Relevant Osteoarthritis and Rheumatoid Arthritis Compared With The General Population
Aleksandra Turkiewicz¹, Tuhina Neogi², George Peat³ and Martin Englund⁴, ¹Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Research Institute for Primary Care & Health Sciences, Keele University, Keele, United Kingdom, ⁴Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: There is strong evidence in support of increased mortality in patients with rheumatoid arthritis (RA), while the relation is more controversial in osteoarthritis (OA).…

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