Abstract Number: 2856 • 2014 ACR/ARHP Annual Meeting
Update on Long-Term Outcomes after Reversible Cerebral Vasoconstriction Syndrome (RCVS)
Background/Purpose RCVS is characterized by acute onset of severe headaches, with or without neurologic deficit with evidence of reversible cerebral vasoconstriction. We have previously reported…Abstract Number: 2857 • 2014 ACR/ARHP Annual Meeting
Restricting Back Pain Is Strongly Associated with Disability in Community-Living Older Persons over the Course of 13 Years
Background/Purpose: Although back pain is common and costly, few longitudinal studies have evaluated the association between back pain severe enough to restrict activity [hereafter referred…Abstract Number: 2858 • 2014 ACR/ARHP Annual Meeting
Education Effects on Outcome Expectations for Exercise in Adults with Knee Osteoarthritis
Background/Purpose Outside of a clinical trial setting, higher outcome expectations for exercise, more education, and greater physical activity are inter-related, and outcome expectations may partly…Abstract Number: 2859 • 2014 ACR/ARHP Annual Meeting
Randomized Controlled Trial of Postoperative Care Navigation in Total Knee Arthroplasty Patients: Does One Size Fit All?
Background/Purpose: A number of TKA recipients have suboptimal improvements after surgery. Our objective was to establish the efficacy of a motivational-interviewing (MI)-based telephone intervention aimed…Abstract Number: 2860 • 2014 ACR/ARHP Annual Meeting
Randomised Comparison of the Effectiveness of a Non-Pharmacological Multidisciplinary Face-to-Face Group-Based Treatment Program Vs. a Telephone-Delivered Treatment Program on Daily Function in Patients with Generalized Osteoarthritis
Background/Purpose: Generalized osteoarthritis (GOA) is a widely accepted and prevalent OA phenotype characterized by the involvement of multiple joints. However, current research and clinical practice…Abstract Number: 2861 • 2014 ACR/ARHP Annual Meeting
Changes in Knee Kinematics from a 6-Week Hip and Trunk Strengthening Program for Persons with Patellofemoral Osteoarthritis
Background/Purpose: Patellofemoral (PF) osteoarthritis (OA) is prevalent in middle-aged adults. Aberrant lower extremity (LE) biomechanics is one etiology of knee OA. Reduced peak knee flexion…Abstract Number: 2862 • 2014 ACR/ARHP Annual Meeting
Satisfaction Following Total Knee Replacement: Journey or Destination?
Background/Purpose: Total knee replacement (TKR) outcome is often assessed with measures of pain and function (fxn), but there is no consensus on whether surgery should…Abstract Number: 2863 • 2014 ACR/ARHP Annual Meeting
IgG Antiphospholipid Antibodies Enhance Stroke Damage: An in Vivo Ischemia/Reperfusion Study
Background/Purpose Circulating pathogenic antiphospholipid antibodies (aPL) are the hallmark of antiphospholipid syndrome (APS) and a major risk factor for ischemic stroke, with up to one…Abstract Number: 2864 • 2014 ACR/ARHP Annual Meeting
Markers of Thrombotic Events in Autoimmune Diseases:Comparison of Antiphospholipid Score (aPL-S) and Global Anti-Phospholipid Syndrome Score (GAPSS)
Background/Purpose Recently, new scoring systems to quantify the probability for the diagnosis of antiphospholipid syndrome (APS) have been proposed in sequence: the Antiphospholipid Score(aPL-S) and…Abstract Number: 2865 • 2014 ACR/ARHP Annual Meeting
The Cellular Effects of ANTI-Factor Xa Antibodies Isolated from Patients with Antiphospholipid Syndrome ARE Inhibited By Factorxa Inhibitors, Hydroxychloroquine and Fluvastatin
Background/Purpose Recently we showed that FXa reactive IgG in patients with the antiphospholipid syndrome (APS) displayed higher avidity binding to FXa and had greater functional…Abstract Number: 2866 • 2014 ACR/ARHP Annual Meeting
External Validation of the Global Anti-Phospholipid Syndrome Score in Comparison to IgG Antibodies Directed Against Domain I of ß2-Glycoprotein I. a Prospective Multicentre Cohort Study
Background/Purpose: Our objectives were 1- to perform an external validation of the Global Anti-Phospholipid Syndrome Score (GAPSS) and 2- to compare prognostic significances of GAPPS…Abstract Number: 2867 • 2014 ACR/ARHP Annual Meeting
Antiphospholipid Antibodies Promote the Release of Neutrophil Extracellular Traps: a New Mechanism of Thrombosis in the Antiphospholipid Syndrome
Background/Purpose: Antiphospholipid antibodies (aPL), especially those targeting beta-2-glycoprotein I, are known to activate endothelial cells, monocytes, and platelets, with prothrombotic implications. However, the interaction of…Abstract Number: 2868 • 2014 ACR/ARHP Annual Meeting
Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Clinical Database and Repository Initial Analysis
Background/Purpose: APS ACTION International Clinical Database and Repository (“Registry”) was created to study the natural course of disease over 10 years in persistently aPL-positive patients…Abstract Number: 2869 • 2014 ACR/ARHP Annual Meeting
TLR7 Influences Autoreactive B Cell Selection in the Germinal Center
Background/Purpose: TLR7 is required for the generation of anti-RNA antibodies and excess TLR7 confers a SLE-like phenotype in mice. Recent studies have shown that TLR7…Abstract Number: 2870 • 2014 ACR/ARHP Annual Meeting
B Cell-Intrinsic Deletion of the Type 1 Interferon Receptor Does Not Impact the Development of Murine Lupus
Background/Purpose Type 1 interferon (IFN) is strongly implicated in lupus pathogenesis, and patients with SLE frequently express a “type 1 IFN gene signature”. Type 1…
ACR Meeting Abstracts