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  • Abstract Number: 2932 • 2014 ACR/ARHP Annual Meeting

    Increased Risk of Deep Vein Thrombosis and Pulmonary Embolism in Sjögren’s Syndrome: A General Population-Based Cohort Study

    Marko Yurkovich1, Hyon K. Choi2, Eric C. Sayre3, Kamran Shojania4 and J. Antonio Avina-Zubieta5, 1Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Boston University School of Medicine, Boston, MA, 3Arthritis Research Centre of Canada, Richmond, BC, Canada, 4Rheumatology, University of British Columbia, Vancouver, BC, Canada, 5Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada

    Background/Purpose: There is limited data available on the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) in Sjögren's Syndrome (SjS). We estimated the…
  • Abstract Number: 2933 • 2014 ACR/ARHP Annual Meeting

    Metabolic Syndrome, Adipocytokines and Inflammation in Sjögren’s Syndrome

    Kristopherson Lustosa Augusto1, Eloisa Bonfá2, Rosa M. R. Pereira1, Cleonice Bueno3, Vilma S. T. Viana4 and Sandra G. Pasoto5, 1Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 2Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, 3Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 4Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil

    Background/Purpose Systemic inflammation has been linked to increased frequency of metabolic syndrome (MetS) in autoimmune diseases. However, there are no studies concerning the frequency of…
  • Abstract Number: 2934 • 2014 ACR/ARHP Annual Meeting

    Abatacept reduces Circulating Effector Memory T-Helper Cells in Patients with Primary Sjögren’s Syndrome

    Gwenny Verstappen1, Wayel H. Abdulahad2, Petra M. Meiners3, Suzanne Arends4, Silvia Beijer-Liefers5, Arjan Vissink3, Frans G.M. Kroese4 and Hendrika Bootsma4, 1Rheumatology & Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 2Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, 3Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 4Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 5University Medical Center Groningen, University of Groningen, Groningen, Netherlands

    Background/Purpose In an open-label proof of concept study, Abatacept has been identified as an effective and safe treatment modality in primary Sjögren’s syndrome (pSS). Abatacept…
  • Abstract Number: 2935 • 2014 ACR/ARHP Annual Meeting

    Attainment of Minimal Disease Activity Using Methotrexate in Psoriatic Arthritis

    Barry J. Sheane1, Arane Thavaneswaran2, Dafna D. Gladman2 and Vinod Chandran2, 1Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose Methotrexate (MTX) is used as first-line treatment in psoriatic arthritis (PsA); however, the extent of the disease-modifying effect of MTX on PsA, if any,…
  • Abstract Number: 2895 • 2014 ACR/ARHP Annual Meeting

    Habitual Running Any Time in Life Is Not Detrimental and May be Protective of Symptomatic Knee Osteoarthritis: Data from the Osteoarthritis Initiative

    Grace H. Lo1, Jeffrey B. Driban2, Andrea Kriska3, Kristi Storti3, Timothy E. McAlindon4, Richard Souza5, Charles B. Eaton6, Nancy J. Petersen7 and Maria E. Suarez-Almazor8, 1VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 2Tufts Medical Center, Boston, MA, 3University of Pittsburgh, Pittsburgh, PA, 4Division of Rheumatology, Tufts Medical Center, Boston, MA, 5University of California, San Francisco, San Francisco, CA, 6Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, 7Medicine, Baylor College of Medicine, Houston, TX, 8The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX

    Background/Purpose Controversy exists regarding whether habitual running is beneficial versus harmful to the knee.  Chronic mechanical overloading could potentially physically damage structures within the knee. …
  • Abstract Number: 2896 • 2014 ACR/ARHP Annual Meeting

    a Multi-Center Double-Blind, Randomized, Controlled Trial (db-RCT) to Evaluate the Effectiveness and Safety of Co-Administered Traumeel® (Tr14) and Zeel® (Ze14) Intra‑articular (IA) Injections Versus IA Placebo in Patients with Moderate-to-Severe Pain Associated with OA of the Knee

    Carlos Lozada1, Eve del Rio2, Donald Reitberg2, Robert Smith2, Charles Kahn3 and Roland W. Moskowitz4, 1Rheumatology, University of Miami Miller School of Medicine, Miami, FL, Miami, FL, 2Clinical Research, Rio Pharmaceutical Services, LLC, Bridgewater, NJ, 3South Florida Rheumatology, Hollywood, FL, 4Div of Rheum/Dept of Medicine, University Hospitals Case Medical Center, Cleveland, OH

    Background/Purpose: Tr14 & Ze14 is a combination of dilute biological and mineral extracts administered IA for painful knee OA.  In response to clinician impressions of…
  • Abstract Number: 2897 • 2014 ACR/ARHP Annual Meeting

    Exercise Therapy and/or Manual Therapy for Hip or Knee Osteoarthritis: 2-Year Follow-up of a Randomized Controlled Trial

    J. Haxby Abbott1, Cathy Chapple2, Daniel Pinto3, Alexis Wright4 and Jean-Claude Theis5, 1Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, 2School of Physiotherapy, University of Otago, Dunedin, New Zealand, 3Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, 4Department of Physical Therapy, High Point University, High Point, NC, 5Centre for Musculoskeletal Outcomes Research, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand

    Background/Purpose: Although both exercise therapy and manual therapy have evidence supporting their effectiveness in people with hip and knee osteoarthritis (OA), few clinical trials have…
  • Abstract Number: 2898 • 2014 ACR/ARHP Annual Meeting

    New Insights into the Primary Care Osteoarthritis Consultation with Implications for Practice

    Zoe Paskins1, Tom Sanders1, Peter Croft1 and Andrew Hassell2, 1Research Institute for Primary Care and Health Sciences, Keele University, Keele, United Kingdom, 2School of Medicine, Keele University, Keele, United Kingdom

    Background/Purpose Osteoarthritis (OA) is the commonest long term condition in primary care. Existing international guidance suggests that much can be done to improve patient outcomes…
  • Abstract Number: 2899 • 2014 ACR/ARHP Annual Meeting

    High Dose Aspirin for Treating Kawasaki Disease – Outdated Myth or Effective Aid?

    Gil Amarilyo1, Yael Koren2, Dafna Brik Simon3, Maskit Bar-Meir4, Hilla Bahat5, Mona Hanna Helou6, Amir Mendelson7, Yackov Berkun8, Eli Eisenstein9, Yonatan butbul Aviel10, Galia Barkai11, Yoav Bolkier11, Shai Padeh11, Philip J. Hashkes12, Riva Brik10, Liora Harel1 and Yosef Uziel13, 1Pediatric Rheumatology Unit, Schneider Children's Medical Center of Israel, Petach Tikvah, Israel, 2Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 3Schneider Children's Medical Center of Israel, Petach Tikvah, Israel, 4Infectious Diseases, Shaare-Zedek Medical Center, Jerusalem, Israel, 5Pediatrics, Assaf Harofeh Medical Center, Zerifin, Israel, 6Pediatrics B Department, Rambam Medical Center, Haifa, Israel, 7Pediatric Rheumatology, Meir Medical Center, Kfar Saba, Israel, 8Pediatrics and Pediatric Rheumatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel, 9Dept of Pediatrics, Hadassah Hebrew University Medical Center, Jerusalem, Israel, 10Pediatric Rheumatology, Rambam Medical Center, Haifa, Israel, 11Sheba Medical Center, Tel-Hashomer, Israel, 12Pediatrics, Shaare-Zedek Medical Center, Jerusalem, Israel, 13Pediatric Rheumatology Unit , Department of Pediatrics, Meir Medical Center, Kfar Saba, Israel

    Background/Purpose: Kawasaki disease (KD) is generally treated with intravenous immunoglobulin (IVIG) together with high anti-inflammatory doses of acetyl salicylic acid (ASA), which is subsequently switched…
  • Abstract Number: 2900 • 2014 ACR/ARHP Annual Meeting

    Clinically Inactive Disease in Juvenile Dermatomyositis – a Proposed Revision to the Pediatric Rheumatology International Trials Organisation Criteria

    Beverley Almeida1, Raquel Campanilho-Marques2, Katie Arnold2, Lucy R. Wedderburn3,4, Clarissa A Pilkington5 and Kiran Nistala6, 1Department of Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom, 2Infection, Inflammation and Rheumatology Section, UCL Institute for Child Health, London, United Kingdom, 3Institute of Child Health, University College London, London, United Kingdom, 4Arthritis Research UK Centre for Adolescent Rheumatology,, UCL, UCLH, GOSH NHS Trust, London, United Kingdom, 5Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom, 6Centre for Rheumatology, University College London, London, United Kingdom

    Background/Purpose: Juvenile dermatomyositis (JDM) affects 3 children/million/year with myositis and skin disease being the typical features. The Pediatric Rheumatology International Trials Organisation (PRINTO) have recently…
  • Abstract Number: 2901 • 2014 ACR/ARHP Annual Meeting

    Predictors of Relapse after Discontinuing Systemic Treatment in Childhood Autoimmune Chronic Uveitis

    Gabriele Simonini1, Claudia Bracaglia2, Marco Cattalini3, Andrea Taddio4, Alice Brambilla5, Cinzia DeLibero6, Denise Pires Marafon7, Roberto Caputo6 and Rolando Cimaz1, 1Pediatric Rheumatology, Anna Meyer Children's Hospital-University of Firenze, Florence, Italy, 2Department of Pediatric Medicine, Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy, 3Pediatric Clinic, Spedali Civili di Brescia and University of Brescia, Pediatric Immunology and Rheumatology Unit, Brescia, Italy, 4Institute of Child Health, IRCCS Burlo Garofolo, University of Trieste, Trieste, Italy, 5Anna Meyer Children's Hospital-University of Firenze, Florence, Italy, 6Ophthalmology Unit, Anna Meyer Children's Hospital, Florence, Italy, 7Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy

    Background/Purpose Information regarding the natural clinical history of a child on systemic treatment due to auto-immune chronic uveitis would be helpful in driving duration therapy.…
  • Abstract Number: 2902 • 2014 ACR/ARHP Annual Meeting

    The Health Status of Patients with Juvenile Idiopathic Arthritis (JIA) Significantly Worsens after Transfer from Pediatric to Adult Care

    Kirsten Minden1, Jens Klotsche2, Martina Niewerth2, Angela Zink3 and Gerd Horneff4, 1Chidlrens´ hospital, Charité University Medicine, Berlin, Germany, 2Epidemiology unit, German Rheumatism Research Center, Berlin, Germany, 3German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, 4Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany

    Background/Purpose A minority of patients with polyarticular JIA enter adulthood in drug free remission. Thus, patients are in need of care beyond adolescence. There is…
  • Abstract Number: 2903 • 2014 ACR/ARHP Annual Meeting

    Early Outcomes in Pediatric Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV)

    Kimberly Morishita1, Susanne Benseler2, Rae S.M. Yeung3, Thomas Mason II4, Dawn Wahezi5, Kenneth N. Schikler6, Erica F. Lawson7, Susan Nielsen8, Sirirat Charuvanij9, Paul Dancey10, Susan Shenoi11, Linda Wagner-Weiner12, Angelyne Sarmiento1, David A. Cabral13 and For the PedVas Initiative1, 1BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 2Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, 3Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 4Division of Rheumatology - Department of Medicine, Mayo Clinic, Rochester, MN, 5Pediatric Rheumatology, Children's Hospital at Montefiore, Bronx, NY, 6Department of Pediatrics, Univ of Louisville Schl of Med, Louisville, KY, 7Pediatrics, University of California, San Francisco, San Francisco, CA, 8Pediatric rheumatology, Rigshospitalet, Copenhagen, Denmark, 9Pediatrics, Siriraj Hospital, Bangkok, Thailand, 10Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, 11Pediatric Rheumatology, Seattle Childrens Hospital, seattle, WA, 12Pediatric Rheumatology, University of Chicago Hospital, Chicago, IL, 13Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose:  Childhood AAV is rare and outcome studies are limited.  The PedVas Study is an international initiative collecting clinical data (to A Registry of Childhood…
  • Abstract Number: 2904 • 2014 ACR/ARHP Annual Meeting

    Clinical and Radiological Features of Down’s Arthropathy

    Charlene Foley, Orla Killeen and Emma Jane MacDermott, The National Centre for Paediatric Rheumatology, Dublin, Ireland

    Background/Purpose The ‘Arthropathy of Down syndrome’ was first described in 1984. Three decades on we still have limited literature on the clinical & radiological features…
  • Abstract Number: 2905 • 2014 ACR/ARHP Annual Meeting

    The IL-6/Th17 Axis Promotes Autoantibody-Associated Autoimmune Valvular Carditis in Mice

    Jennifer L. Auger1, Brianna J. Engelson2, Yaya Wang3, Erik J. Peterson4 and Bryce A. Binstadt5, 1Center for Immunology and Department of Pediatrics, University of Minnesota, Minneapolis, MN, 2Pediatrics, University of Minnesota, Minneapolis, MN, 3Medicine, University of Minnesota, Minneapolis, MN, 4University of Minnesota, Minneapolis, MN, 5Pediatric Rheumatology, University of Minnesota, Minneapolis, MN

    Background/Purpose: Autoimmune valvular carditis occurs in patients with systemic lupus erythematosus, rheumatoid arthritis and rheumatic fever, but the pathogenic mechanisms remain incompletely defined. Spontaneous autoimmune…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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