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  • Abstract Number: 219 • 2014 ACR/ARHP Annual Meeting

    DXA Body Composition, Sarcopenia and Knee and Hip Osteoarthritis: Results from the Khoala Cohort

    Clémence Jeanmaire1, Isabelle Chary-Valkenaere1, Damien Loeuille2, Lorraine Bernard3 and Anne-Christine Rat,4, 1Rheumatology, CHU Nancy, Vandoeuvre Les Nancy, France, 2Rheumatology, CHU Brabois, Vandoeuvre les Nancy, France, 3CHU Nancy, Pôle S2R, Epidémiologie et Evaluation Cliniques, INSERM, CIC-EC, CIE6, Vandoeuvre Les Nancy, France, 4Université de Lorraine, Nancy, F-54000, France; Inserm, , CIC-EC, CIC 1433, Nancy, F-54000, France; CHU de Nancy, Clinical Epidemiology and Evaluation Department, Nancy, F-54000, France; CHU de Nancy, Rheumatology department, Nancy, France

    Background/Purpose Obesity is a well known risk factor for the development and progression of knee osteoarthritis (OA), and to a lesser extent of hip OA.…
  • Abstract Number: 218 • 2014 ACR/ARHP Annual Meeting

    Surface Area and Fatty Infiltration of Vastus Medialis Measured By Magnetic Resonance Imaging Are Risk Factors for the Progression of Knee Osteoarthritis and Discriminate Two Osteoarthritis Phenotypes

    Johanne Martel-Pelletier1, Jean-Pierre Raynauld1, François Abram2, Marc Dorais3, Yuanyuan Wang4, Jessica Fairley4, Flavia Cicuttini4 and Jean-Pierre Pelletier1, 1Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, 2Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, 3StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada, 4Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

    Background/Purpose: Osteoarthritis (OA) is the most common arthritic condition but its treatment still remains symptomatic. Understanding factors affecting the progression of this disease may enable…
  • Abstract Number: 217 • 2014 ACR/ARHP Annual Meeting

    The Relationship of Quadriceps and Hamstrings Intramuscular Fat and Lean Muscle with Power in Women with Knee Osteoarthritis

    Michael J. Davison1, Monica R. Maly2, Karen A. Beattie3, Peter J. Keir4 and Jonathan D. Adachi5, 1Medical Sciences, McMaster University, Hamilton, ON, Canada, 2School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, 3Medicine, McMaster University, Hamilton, ON, Canada, 4Kinesiology, McMaster University, Hamilton, ON, Canada, 5Division of Rheumatology, McMaster University, Hamilton, ON, Canada

    Background/PurposeReduced quadriceps and hamstrings strength is a risk factor for knee osteoarthritis (OA). This strength loss is partly due to the loss of lean muscle…
  • Abstract Number: 211 • 2014 ACR/ARHP Annual Meeting

    Association Between Baseline External Knee Adduction and Flexion Moments during Gait and Medial Tibiofemoral Cartilage Thickness Loss over Two Years in Persons with Knee Osteoarthritis (OA)

    Alison H. Chang1, Kirsten C. Moisio2, Felix Eckstein3, Joan S. Chmiel4, Orit Almagor2, Pottumarthi Prasad5, Karen W. Hayes2, Laura Belisle2, Yunhui Zhang2, Jamie Rayahin6 and Leena Sharma2, 1Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, 2Northwestern University, Chicago, IL, 3Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 4Department of Preventive Medicine, Northwestern University, Chicago, IL, 5NorthShore University HealthSystem, Evanston, IL, 6University of Illinois at Chicago, Chicago, IL

    Background/Purpose The external knee adduction moment (KAM) during gait has been characterized as a surrogate for dynamic medial knee load and is believed to be…
  • Abstract Number: 210 • 2014 ACR/ARHP Annual Meeting

    Preliminary Assessment of Predictive Validity of Cartilage Thickness MRI Biomarkers in Knee OA – the Fnih OA Biomarkers Consortium

    David J. Hunter1, Jamie E. Collins2, Michael C. Nevitt3, John A. Lynch4, Virginia B. Kraus5, Jeffrey N. Katz6, Elena Losina2, Frank Roemer7, Ali Guermazi8, Wolfgang Wirth9 and Felix Eckstein10, 1Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 2Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 3Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 4Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, 5Medicine/Rheumatology, Duke University Medical Center, Durham, NC, 6Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA, 7Klinikum Augsburg, Augsburg, Germany, 8Radiology, Boston University School of Medicine, Boston, MA, 9Strubergasse 21, Paracelsus Medical University, Salzburg, Austria, 10Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria

    Background/Purpose We sought to investigate if cartilage thickness change over 24 months predicts clinically relevant progression (radiographic and/or symptomatic) in knee OA over a 48…
  • Abstract Number: 209 • 2014 ACR/ARHP Annual Meeting

    Physical Performance and Obesity Measures Are Associated with Tibial Cartilage Volume and Explains the Sex Difference in Cartilage Volume

    Benny Samuel Eathakkattu Antony1, Alison Venn2, Flavia Cicutinni3, Lyn March4, Leigh Blizzard5, Terry Dwyer6, Marita Cross7, Graeme Jones8 and Changhai Ding8, 1Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, 2Epidemiology, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 3Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia, 4Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 5Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 6Director, Murdoch Children's Research Institute, Melbourne, Australia, 7University of Sydney Institute of Bone and Joint Research, Royal North Shore Hospital, Sydney, Australia, 8Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia

    Background/Purpose The factors associated with knee cartilage volume in younger population are insufficiently explored. The aims of this study were to describe the associations between…
  • Abstract Number: 208 • 2014 ACR/ARHP Annual Meeting

    Correlates of Knee Bone Marrow Lesions in Younger Adults

    Benny Samuel Eathakkattu Antony1, Graeme Jones2, Alison Venn3, Lyn March4, Flavia Cicutinni5, Andrew Halliday6, Leigh Blizzard7, Marita Cross8, Terry Dwyer9 and Changhai Ding2, 1Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, 2Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, 3Epidemiology, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 4Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 5Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia, 6Radiology, Royal Hobart Hospital, Australia, Hobart, Australia, 7Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 8University of Sydney Institute of Bone and Joint Research, Royal North Shore Hospital, Sydney, Australia, 9Director, Murdoch Children's Research Institute, Melbourne, Australia

    Background/Purpose: Bone marrow lesions (BMLs) of the knee joint are a key player in osteoarthritis of the knee. However, little is known of their determinants,…
  • Abstract Number: 207 • 2014 ACR/ARHP Annual Meeting

    Changes in Knee Compartment Distriubtion of Cartilage Loss and Bone Marrow Lesions over 7 Years: The MOST Study

    Joshua Stefanik1, Ali Guermazi2, Jingbo Niu3, Frank Roemer4, C.E. Lewis5, Neil A. Segal6, Michael Nevitt7 and David T. Felson8, 1Clinical Epidemiology, Boston University, Boston, MA, 2Radiology, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, 4Klinikum Augsburg, Augsburg, Germany, 5University of Alabama at Birmingham, Birmingham City, AL, 6Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, 7Epidemiology and Biostatistics, UCSF, San Francisco, CA, 8Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Knee osteoarthritis (OA) occurs in both the patellofemoral joint (PFJ) and tibiofemoral joint (TFJ). Little is known about the natural history of OA and…
  • Abstract Number: 206 • 2014 ACR/ARHP Annual Meeting

    Risk Factors for Increased Extrusion of the Meniscus Body in Subjects Free of Radiographic Knee Osteoarthritis: 6-Year MRI Data from the Osteoarthritis Initiative

    Fan Zhang1, Jaanika Kumm2, Fredrik Svensson1, Aleksandra Turkiewicz1, Richard Frobell1 and Martin Englund3, 1Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, 2Radiology, Tartu University, Tartu, Estonia, 3Department of Orthopedics, Lund University, Lund, Sweden

    Background/Purpose Meniscal body extrusion on knee MRI is strongly associated with the development and progression of knee osteoarthritis (OA). However, there is very limited evidence…
  • Abstract Number: 205 • 2014 ACR/ARHP Annual Meeting

    Natural History and Clinical Significance of Meniscal Tears over 8 Years in a Largely Non-Osteoarthritic Cohort

    Hussain Ijaz Khan1, Dawn Aitken1, Changhai Ding2, Leigh Blizzard3, Jean-Pierre Pelletier4, Johanne Martel-Pelletier4, Flavia Cicutinni5 and Graeme Jones2, 1Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, 2Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, 3Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 4Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, 5Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia

    Background/Purpose: Meniscal tears are a key player in knee osteoarthritis (OA) and family history of the disease has been shown to play an important role.…
  • Abstract Number: 204 • 2014 ACR/ARHP Annual Meeting

    Ultrasonographic Predictors for Clinical and Radiological Progression in Knee Osteoarthritis after 2 Years Follow up

    Karen Bevers1, Johanna E. Vriezekolk2, J.W.J. Bijlsma3, Els van den Ende4 and Alfons A. den Broeder2, 1Rheumatology, St Maartenskliniek, Nijmegen, Netherlands, 2Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 3Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 4Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands

    Background/Purpose Pathophysiology of osteoarthritis (OA) is not completely understood. Identifying patients with progression might help to direct future research on therapeutic interventions. As OA is…
  • Abstract Number: 203 • 2014 ACR/ARHP Annual Meeting

    Predictors of Radiographic Progression of Interphalangeal Finger Joints in Erosive Osteoarthritis: A Prospective Study

    Paulien Meersseman1, Celine Van De Vyver2, Gust Verbruggen1, Dirk Elewaut1 and Ruth Wittoek1, 1Rheumatology, Department of Rheumatology Ghent University Hospital, Ghent, Belgium, 2Department of Rheumatology Ghent University Hospital, Ghent, Belgium

    Background/Purpose Predictors of radiographic progression in erosive osteoarthritis (OA) are important in identifying patients with high risk of disease activity and consequently functional loss. Disease…
  • Abstract Number: 202 • 2014 ACR/ARHP Annual Meeting

    Is Schuss View Alone Enough for the Diagnosis of Femorotibial Osteoarthritis ? the Khoala Cohort Study

    Christian Roux1, Bernard Mazieres2, Evelyne Verrouil2, Anne-Christine Rat,3, Patrice Fardellone4, Bruno Fautrel5, Jacques Pouchot6, Alain Saraux7, Francis Guillemin8, Liana Euller Ziegler9 and Joel Coste10, 1Rhumatologie, Hopital Archet 1 - Université Nice Sophia Antipolis, Nice, France, 2CHU Toulouse, Toulouse, France, 3Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, Nancy, France, 4Service de Rhumatologie, Hôpital Nord, C.H.U. d'Amiens, Amiens, France, 5CHU - Hôpital Pitié-Salpêtrière, Paris, France, 6Medecine Interne, Hopital Louis Mourier, Colombes, FRANCE, France, 7Rheumatology, CHU de la Cavale Blanche and Université Bretagne occidentale, Brest Cedex, France, 8INSERM, Centre d'Investigation Clinique - Epidémiologie Clinique (CIC-EC) CIE6, Nancy, France, 9151 rte de St Antoine de Gines, CHU de Nice -Université Nice Sophia Antipolis, Nice, France, 10CHU Hotel Dieu, Paris, France

    Background/Purpose: Associating an anteroposterior (AP) extended-knee X-ray with a semiflexed AP or posteroanterior (PA) view is considered the gold standard for radiologically diagnosing tibiofemoral osteoarthritis…
  • Abstract Number: 200 • 2014 ACR/ARHP Annual Meeting

    Leg Length Inequality and Hip Osteoarthritis

    Chan Kim1, Jingbo Niu2, Mary Clancy3, Ali Guermazi4, Michael C. Nevitt5, Neil A. Segal6, William F. Harvey7, Cora E Lewis8 and David T. Felson9, 1Rheumatology, Boston University, Boston, MA, 2Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, 3Clinical Epidemiology, Boston University Sch Med, Boston, MA, 4Radiology, Boston University School of Medicine, Boston, MA, 5Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 6Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, 7Rheumatology, Tufts Medical Center, Boston, MA, 8Division of Preventive Medicine, University of Alabama Birmingham School of Medicine, Birmingham, AL, 9Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom

    Background/Purpose Leg length inequality (LLI), a side-to-side difference in lower limb lengths, is common.  In the Multicenter Osteoarthritis Study (MOST), in persons with LLI, the…
  • Abstract Number: 199 • 2014 ACR/ARHP Annual Meeting

    Increasing Complexity of Patients Undergoing Primary Total Hip Arthroplasty in the U.S

    Jasvinder A. Singh1 and David Lewallen2, 1University of Alabama and VA Medical Center, Birmingham, AL, 2Orthopedics, Mayo Clinic college of medicine, Rochester, MN

    Background/Purpose: To examine the time-trends in key demographic and clinical characteristics of patients undergoing primary total hip arthroplasty (THA).Methods: We used the data from the…
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