Abstracts Archive - Page 2036 of 2605 - ACR Meeting Abstracts

Abstract Number: 2975 • 2014 ACR/ARHP Annual Meeting
Residual Large Joint Synovitis By Power Doppler Ultrasonography Is Associated with Higher Disease Activity and Significant Impact of Disease in Multi-Ethnic Asian Patients with Established Rheumatoid Arthritis
Yu Xiao Guo¹, Manjari Lahiri^2,3 and Peter Cheung^2,3, ¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, ²Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, ³Division of Rheumatology, National University Hospital, Singapore, Singapore
Background/Purpose Regular monitoring of disease activity with appropriate modification of disease-modifying anti-rheumatic drug (DMARD) therapy results in improved radiographic and functional outcomes in patients with…
Abstract Number: 2936 • 2014 ACR/ARHP Annual Meeting
Is Ankylosing Spondylitis a Risk Factor for Cardiovascular Diseases, and How Does These Risks Compare to Those in Rheumatoid Arthritis?
Johan Askling¹, Lennart Jacobsson² and Jonas Eriksson¹, ¹Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ²sahlrenska academy, gothenburg, Sweden
Background/Purpose Patients with RA are at increased risk of cardiovascular (CV) diseases, including acute coronary syndromes (ACS), deep venous thromboembolism (DVT) and pulmonary embolism (PE),…
Abstract Number: 2937 • 2014 ACR/ARHP Annual Meeting
Evaluation of Referral Models for Axial Spondyloarthritis in Primary Care in the Spondyloarthritis Caught Early Cohort
Ozair Abawi¹, Rosaline van den Berg¹, Désirée van der Heijde² and Floris van Gaalen¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands
Background/Purpose Several models have been proposed to refer patients (pts) with possible axial spondyloarthritis (axSpA) from primary care to the rheumatologist. Aim of the study…
Abstract Number: 2938 • 2014 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Placebo-Controlled, 16-Week Study of Subcutaneous Golimumab in Patients with Active Nonradiographic Axial Spondyloarthritis
J Sieper¹, D van der Heijde², M Dougados³, Walter P. Maksymowych⁴, J Boice⁵, G Bergman⁵, S Curtis⁵, A Tzontcheva⁵, S Huyck⁵ and HH Weng⁵, ¹University Clinic Benjamin Franklin, Berlin, Germany, ²Leiden University Medical Center, Leiden, Netherlands, ³Paris-Descartes University, Paris, France, ⁴Department of Medicine, University of Alberta, Alberta, AK, ⁵Merck & Co., Inc., Whitehouse Station, NJ
Background/Purpose Axial spondyloarthritis (axSpA), including ankylosing spondylitis and nonradiographic axial SpA (nr-axSpA), is a chronic inflammatory disease marked by back pain and progressive spinal stiffness.…
Abstract Number: 2939 • 2014 ACR/ARHP Annual Meeting
Increased Diagnosis of Spondyloarthritis in Female Patients Started in the Early Biologic Era
Nisha Nigil Haroon¹, Ping Li², Michael Paterson² and Nigil Haroon³, ¹Department of Medicine, University of Toronto, Toronto, ON, Canada, ²Institute of Clinical Evaluative Sciences, Toronto, ON, Canada, ³Toronto Western Research Institute, Toronto, ON, Canada
Background/Purpose The health and economic impact of spondyloarthritis is considerable and growing. Over the past decade or more, there have been two major changes in…
Abstract Number: 2940 • 2014 ACR/ARHP Annual Meeting
Do Patients with Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis Respond Similarly Well to Nsaids? – a Prospective Study Including Magnetic Resonance Imaging
Xenofon Baraliakos¹, Uta Kiltz¹, Frank Heldmann¹, Heiner Appel², Friedrich Dybowski³, Manfred Igelmann⁴, Ludwig Kalthoff⁵, Dietmar Krause⁶, Hans-Jürgen Menne⁷, Ertan Saracbasi⁸, Elmar Schmitz-Bortz⁹ and Jürgen Braun¹, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Rheumatology and Nephrology Practice, Hamm, Germany, ³Rheumatology Practice, Herne, Germany, ⁴Rheumatology Practice, Bochum, Germany, ⁵Rheumatology practice, Herne, Germany, ⁶Rheumatology practice, Gladbeck, Germany, ⁷Rheumatology practice, Dortmund, Germany, ⁸Rheumatology practice, Oberhausen, Germany, ⁹Rheumatology practice, Hattingen, Germany
Background/Purpose: Patients classified as axial spondyloarthritis (axSpA) may have ankylosing spondylitis (AS) or non-radiographic axSpA (nr-axSpA). Treatment recommendations for AS consider non-steroidal anti-inflammatory drugs (NSAIDs)…
Abstract Number: 2941 • 2014 ACR/ARHP Annual Meeting
Physical Function Is Independently Associated with Mortality Among Individuals with Knee and/or Hip OA: The Johnston County Osteoarthritis Project
Rebecca J. Cleveland¹, Todd Schwartz¹, Jordan B. Renner², Joanne M. Jordan³ and Leigh F. Callahan⁴, ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²University of North Carolina Department of Radiology, Chapel Hill, NC, ³University of North Carolina Dept of Epidemiology, Chapel Hill, NC, ⁴Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC
Background/Purpose Declining physical function (PF) is a common consequence of osteoarthritis (OA), and poor PF is associated with death. It is possible that the resulting…
Abstract Number: 2942 • 2014 ACR/ARHP Annual Meeting
A Longitudinal Population-Based Study 1994-2010 of Age, Period, and Cohort Effects in the Prevalence of Arthritis: The Effect of Improving Socioeconomic Status and Increasing Obesity over Time
Elizabeth M. Badley^1,2, Mayilee Canizares^3,4, Anthony V. Perruccio^5,6, Sheilah. Hogg-Johnson^6,7 and Monique A.M. Gignac^6,7, ¹Division Health Care and Outcomes Research,, Toronto Western Research Institute, Toronto, ON, Canada, ²Dalla Lana School of Public Health,, University of Toronto, Toronto, ON, Canada, ³Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, ON, Canada, ⁴Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada, ⁵Arthritis Program, Toronto Western Hospital, Toronto, ON, Canada, ⁶Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ⁷Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: To examine birth cohort and period effects in the age-trajectories of reported arthritis from 1994 to 2010 in a representative sample of Canadians; and…
Abstract Number: 2943 • 2014 ACR/ARHP Annual Meeting
Severity of Foot Pain Is Linked to the Prevalence of Depressive Symptoms: The Framingham Foot Study
Arunima Awale¹, Alyssa B. Dufour², Patricia P. Katz³, Virginia A. Casey¹ and Marian T. Hannan⁴, ¹Institute for Aging Research, Hebrew SeniorLife, Boston, MA, ²Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School & Beth Israel Deaconess Medical Center, Boston, MA, ³Medicine, University of California, San Francisco, CA, ⁴Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
Background/Purpose: While a number of risk factors for foot pain are established, the relation between depression and foot pain has not been well studied. The…
Abstract Number: 2944 • 2014 ACR/ARHP Annual Meeting
Sedentary Time Is an Independent Risk Factor for Disability Onset Among Adults at Elevated Risk: Prospective Cohort Study
Jungwha Lee¹, Jing Song², Barbara Ainsworth³, Rowland W. Chang⁴, Linda S. Ehrlich-Jones⁵, Christine Pellegrini⁶, Pamela Semanik⁷, Dorothy D. Dunlop² and Leena Sharma⁸, ¹Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Arizona State University, Pheonix, AZ, ⁴Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Rehabilitation Institute of Chicago, Chicago, IL, ⁶Center for Behavioral Health, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Rush University, Chicago, IL, ⁸Northwestern University, Chicago, IL
Background/Purpose: Disability threatens personal independence and is a major driver of health care costs. Physical activity has been shown to prevent disability. Sedentary behavior, already…
Abstract Number: 2945 • 2014 ACR/ARHP Annual Meeting
Foot Structure and Function Show Associations with Lower Extremity Physical Function
Yvonne M. Golightly¹, Marian T. Hannan², Patricia P. Katz³, Howard J. Hillstrom⁴, Alyssa B. Dufour⁵ and Joanne M. Jordan⁶, ¹Gillings School of Global Public Health, Dept of Epidemiology, Thurston Arthritis Research Center, Injury Prevention Research Center, University of North Carolina Dept of Epidemiology, Chapel Hill, NC, ²Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, ³Medicine, University of California, San Francisco, San Francisco, CA, ⁴Rehabilitation, Hospital Special Surgery (HSS), New York, NY, ⁵Institute for Aging Research, Hebrew SeniorLife & Boston Univ, Boston, MA, ⁶University of North Carolina Dept of Epidemiology, Chapel Hill, NC
Background/Purpose . Foot pain is associated with poorer physical function in older adults, but few studies have examined how foot structure (high / low arches) and…
Abstract Number: 2946 • 2014 ACR/ARHP Annual Meeting
The Association Between Accelerometer Monitored Sedentary Behavior and Observed Physical Function Loss
Pamela Semanik¹, Rowland W. Chang², Jing Song³, Jungwha Lee⁴ and Dorothy D. Dunlop³, ¹Nursing, Rush University College of Nursing, Chicago, IL, ²Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Preservation of function in older adults is critical to maintaining independence. Physical activity interventions often focus on increasing activity while giving limited attention to…
Abstract Number: 2947 • 2014 ACR/ARHP Annual Meeting
Adenosine a_2A Receptor As a Potential New Therapeutic Target for the Prevention/Treatment of Osteoarthritis
Carmen Corciulo¹, Aranzazu Mediero², Tuere Wilder³ and Bruce N. Cronstein⁴, ¹Division of Translational Medicine, Department of Medicine, NYU School of Medicine, New York, NY, ²Medicine, Division of Translational Medicine, NYU School of Medicine, New York, NY, ³Medicine, division of Translational Medicine, NYU School of Medicine, New York, NY, ⁴NYU School of Medicine, Division of Rheumatology, New York, NY
Background/Purpose Osteoarthritis results from trauma, mechanical factors or metabolic changes in bone and cartilage. Adenosine, acting via the A2AR, inhibits inflammation and plays a critical…
Abstract Number: 2948 • 2014 ACR/ARHP Annual Meeting
S100 Proteins Induce Canonical Wnt Signaling, Which Causes Increased Expression of MMPs in the Synovium
Martijn H. van den Bosch¹, Arjen B. Blom², R. Pelle Hoek², Rik F. Schelbergen³, Sylvia W. Suen², Anke E. van Erp², Wim B. van den Berg¹, Peter M. van der Kraan¹ and Peter L. van Lent⁴, ¹Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands, ²Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ³Radboud university medical center, Nijmegen, Netherlands, ⁴Experimental Rheumatology, Experimental Rheumatology, Radboud University, Nijmegen, Netherlands
Background/Purpose: Many osteoarthritis (OA) patients show synovial activation, which is thought to be involved in joint destruction. Previously, we found that the alarmins S100A8 and A9,…
Abstract Number: 2949 • 2014 ACR/ARHP Annual Meeting
Activation of AMP-Activated Protein Kinase (AMPK) By Berberine Limits Both Surgical Knee Instability-Induced and Aging-Related Osteoarthritis in Mice
Ru Bryan¹, Xianling Zhao², Yun Wang³, Han Sol Lee², Hyunje Kim⁴, Alifah Akasdi² and Robert Terkeltaub⁵, ¹Medicine-Rheumatology, VA Medical Center/University of California San Diego, San Diego, CA, ²VAMC, San Diego, CA, ³Medicine-Rheumatology, VA Medical Ctr/UCSD, San Diego, CA, ⁴Internal medicine, School of medicine, Yeungnam University, Daegu, South Korea, ⁵Medicine-Rheumatology, VA Medical Ctr/University of California San Diego, San Diego, CA
Background/Purpose Human knee OA articular cartilage chondrocytes and aged mouse knee cartilage chondrocytes demonstrate decreased activation of master cellular energy bio-sensor AMPK. Moreover, inflammatory stimuli…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].