Abstracts Archive - Page 2036 of 2425 - ACR Meeting Abstracts

Abstract Number: 234 • 2014 ACR/ARHP Annual Meeting
The Decrease in Prescription of Anti-Osteoporotic Drugs Has No Impact on Hip Fracture Incidence
Karine Briot¹, Milka Maravic² and Christian Roux³, ¹Cochin Hospital, Paris Descartes University, Paris, France, ²Hopital Leopold Bellan, Paris, France, ³Paris Descartes University, Cochin Hospital, Paris, France
Background/Purpose Controversies exist about the change in hip fracture incidence among countries. In France, we previously showed that the incidence of hip fractures decreased in…
Abstract Number: 233 • 2014 ACR/ARHP Annual Meeting
Significance of Serum Marker Levels of Wnt/ß-Catenin Signaling Pathway in Patients with Systemic Autoimmune Diseases Under Glucocorticoid Therapy; A Prospective Study
Mai Kawazoe, Kotaro Shikano, Kaichi Kaneko, Shotaro Masuoka, Hiroshi Sato, Emiko Shindo, Natsuki Fujio, Sei Muraoka, Makoto Kaburaki, Nahoko Tanaka, Tatsuhiro Yamamoto, Kenji Takagi, Natsuko Kusunoki, Tomoko Hasunuma and Shinichi Kawai, Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan
Background/Purpose: Glucocorticoids are widely used to treat a variety of diseases, including systemic autoimmune diseases. Although glucocorticoids improve the outcome for patients with these diseases,…
Abstract Number: 232 • 2014 ACR/ARHP Annual Meeting
Significance of Serum Srankl and Osteoprotegerin Concentration in Patients with Rheumatoid Arthritis
Kotaro Shikano, Kaichi Kaneko, Mai Kawazoe, Shotaro Masuoka, Hiroshi Sato, Emiko Shindo, Natsuki Fujio, Makoto Kaburaki, Sei Muraoka, Nahoko Tanaka, Tatsuhiro Yamamoto, Kenji Takagi, Natsuko Kusunoki, Tomoko Hasunuma and Shinichi Kawai, Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan
Background/Purpose Rheumatoid arthritis (RA) is known as a cause of secondary osteoporosis. The previous studies reported that receptor activator for nuclear factor κB ligand (RANKL)…
Abstract Number: 231 • 2014 ACR/ARHP Annual Meeting
Factors Predicting Fracture in the over-75s: An Observational Case-Control Study
Christopher Varley¹, James Fowler², Alexander Oldroyd¹ and Marwan Bukhari³, ¹Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, ²Faculty of Health and Medicine, Lancaster Univeristy, Lancaster, United Kingdom, ³Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom
Background/Purpose In the over 75s the diagnosis of osteoporosis may be assumed following a fracture, making the need for a dual energy absorptiometry scan (DEXA)…
Abstract Number: 230 • 2014 ACR/ARHP Annual Meeting
Risk Factors That Predict Poor Bone Health in Those Aged over 75 Years – a Cross Sectional Study
James Fowler^1,2, Christopher Varley³, Alexander Oldroyd³ and Marwan Bukhari³, ¹Faculty of Health and Medicine, Lancaster Univeristy, Lancaster, United Kingdom, ²University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, United Kingdom, ³Lancaster Medical School, Lancaster University, Lancaster, United Kingdom
Background/Purpose .No studies have been conducted into the over 75 population specifically to assess the risk factors that predict BMD loss. The Framingham Osteoporosis Study…
Abstract Number: 229 • 2014 ACR/ARHP Annual Meeting
Correlates of Heel Bone Mass in Young Adults: The Role of Cholesterol over 20 Years from Childhood to Early Adulthood
Benny Samuel Eathakkattu Antony¹, Changhai Ding², Alison Venn³, Terry Dwyer⁴ and Graeme Jones², ¹Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Epidemiology, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁴Director, Murdoch Children's Research Institute, Melbourne, Australia
Background/Purpose The association between lipids and bone mass in adult life is controversial and there is limited evidence in childhood. The aim of this study…
Abstract Number: 228 • 2014 ACR/ARHP Annual Meeting
Is Adult Hypophosphatasia a Cardiovascular Risk Factor?
Leyre Riancho-Zarrabeitia¹, Maria T. García-Unzueta², Alfonso Corrales³, Juan Gómez-Gerique² and José A. Riancho⁴, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ²Biochemistry, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ³Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ⁴Internal Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL. University of Cantabria, Santander, Spain
Background/Purpose Mild forms of adult hypophosphatasia may have subtle manifestations, and may go unrecognized. The aim of this study was to get a better knowledge of its clinical spectrum. Methods We performed a computerized search of low total alkaline phosphatase among laboratory records. The diagnosis of hypophosphatasia was confirmed by measuring serum pyridoxal phosphate (PLP) and bone alkaline phosphatase. Carotid ultrasonography was performed in patients and controls with a MyLab 70…
Abstract Number: 227 • 2014 ACR/ARHP Annual Meeting
Increasing Fat-Mass May Reverse Bone Loss As Detected By DXA Scan
William Hedges¹ and Marwan Bukhari^2,3, ¹Foundation Programme, Royal Lancaster Infirmary, University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, United Kingdom, ²Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, ³Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom
Background/Purpose: Low body mass index (BMI) is a known risk factor for loss of bone mineral density (BMD). It is a part of the FRAX…
Abstract Number: 226 • 2014 ACR/ARHP Annual Meeting
Improved Prediction of Hip Fracture Using the Health Assessment Questionnaire-Disability Index and FRAX^® in Japanese Patients with Rheumatoid Arthritis: A Prospective Observational Study
Takefumi Furuya¹, Eisuke Inoue², Kensuke Ochi¹, Osamu Ishida³, Atsuo Taniguchi⁴, Shigeki Momohara⁴ and Hisashi Yamanaka¹, ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, ³Orthopedics, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ⁴Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan
Background/Purpose: The World Health Organization Fracture Risk Assessment Tool (FRAX®) algorithm can be used to estimate 10-year probabilities of hip and major osteoporotic fractures. Previously,…
Abstract Number: 225 • 2014 ACR/ARHP Annual Meeting
Association Between Lean Mass and Hip Bone Mineral Density
Charlotte Beaudart¹, Jean-Yves Reginster², Justine Slomian³, Fanny Buckinx⁴ and Olivier Bruyere⁵, ¹Avenue De L'Hopital 3, University of Liège, Liège, Belgium, ²Bone Cartilage Unit, University of Liège, Liège, Belgium, ³Support Unit in Epidemiology and Biostatistics, University of Liège, Liège, Belgium, ⁴Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, ⁵Public Health/Epidemiology, University of Liège, Liège, Belgium
Background/Purpose: Fat mass and lean mass (LM) represent 95% of body weight. However, the role of each component on bone mineral density (BMD) is not…
Abstract Number: 224 • 2014 ACR/ARHP Annual Meeting
Is the Protective Effect of Obesity Against Hip Fracture Due to Changes of Proximal Femur Shape?
Alexander Oldroyd¹ and Marwan Bukhari^1,2, ¹Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, ²Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom
Background/Purpose: The association between increasing body mass index (BMI), increasing bone mineral density (BMD) and lower hip fracture risk has been demonstrated by previous research. Studies…
Abstract Number: 223 • 2014 ACR/ARHP Annual Meeting
Risk Factors for Clinical Vertebral Fractures in Japanese Men and Women with Rheumatoid Arthritis: Results from a Large Prospective Observational Cohort Study
Osamu Ishida¹, Takefumi Furuya², Eisuke Inoue³, Kensuke Ochi², Katsunori Ikari², Atsuo Taniguchi⁴, Hisashi Yamanaka² and Shigeki Momohara⁴, ¹Orthopedics, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ³Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, ⁴Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan
Background/Purpose: Patients with rheumatoid arthritis (RA) are at high risk of developing vertebral fractures. Previously, utilizing data from our Institute of Rheumatology Rheumatoid Arthritis (IORRA)…
Abstract Number: 220 • 2014 ACR/ARHP Annual Meeting
Lower Extremity Presarcopenia Is Associated with the Severity of Knee Pain
Yun-Hong Cheon¹, Wan-Hee Yoo², Young Sun Suh³, Hyun-Ok Kim³, Ki-Soo Park⁴, Sang-Il Lee³ and Hye-Ji Jeon⁴, ¹Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Chonbuk National University School of Medicine, Jeonju, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ⁴Department of Preventive Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea
Background/Purpose Presarcopenia, which is defined as skeletal muscle mass loss, and knee pain have been gained attention with ageing. Little is known about the association…
Abstract Number: 221 • 2014 ACR/ARHP Annual Meeting
An Analysis of Age-Related Loss of Skeletal Muscle Mass and Its Significance on Osteoarthritis in a Korean Population
Hyunje Kim¹, Minjung Kim¹, Choong Ki Lee² and Young Hoon Hong³, ¹Internal medicine, School of medicine, Yeungnam University, Daegu, South Korea, ²Internal medicine, school of medicine, Yeungnam University, Daegu, South Korea, ³Department of Internal medicine, School of Medicine,, Yeungnam University, Daegu, South Korea
Background/Purpose This study was conducted in order to analyze the effects of sarcopenia and sarcopenic obesity on age-related OA of the knee in a Korean…
Abstract Number: 222 • 2014 ACR/ARHP Annual Meeting
OA Phenotypes Rather Than Disease Stage Drive Structural Progression – Identification of Structural Progressors from 2 Phase III Randomized Clinical studies with Symptomatic Knee OA
Morten Asser Karsdal¹, Anne C. Bay-Jensen², Asger Bihlet³, Peter Alexandersen⁴, Inger Byrjalsen³, Bente J. Riis³ and Claus Christiansen³, ¹Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ²Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, ³Nordic Bioscience, Herlev, Denmark, ⁴Center for Clinical and Basic Research, Vejle, Denmark
Background/Purpose: Osteoarthritis (OA) is a heterogeneous disorder, with several possible drivers of disease progression. Up to 50% of OA patients do not structurally progress, emphasizing…

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