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  • Abstract Number: 3003 • 2014 ACR/ARHP Annual Meeting

    Am80 Ameliorates Bleomycin-Induced Dermal Fibrosis By Suppressing the Pro-Fibrotic Phenotype of Fibroblasts, Endothelial Cells, and Immune Cells

    Tetsuo Toyama1, Yoshihide Asano1, Takehiro Takahashi1, Ryosuke Saigusa1, Yohei Ichimura1, Takashi Taniguchi1, Shinji Noda1, Kaname Akamata1, Shinichi Sato1, Takafumi Kadono1 and Koichi Shudo2, 1Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, 2Reseach Foundation ITSUU Laboratory, Tokyo, Japan

    Background/Purpose:  Am80 is a synthetic retinoid serving as an agonist for retinoic acid receptor α/β with chemical and pharmacological advantages over all-trans retinoic acid, such…
  • Abstract Number: 3004 • 2014 ACR/ARHP Annual Meeting

    Autoantibody-Mediated Raynaud’s Phenomenon: Animal Model and Human Disease

    Dana P. Ascherman1,2, Yunjuan Zang3, Laisel Martinez4, Judith Pignac-Kobinger5, Irina Fernandez3 and Eric L. Greidinger3,4, 1Medicine/Rheumatology, University of Miami, Miami, FL, 2Rheumatology, Miami VAMC, Miami, FL, 3Rheumatology, University of Miami, Miami, FL, 4Miami VAMC, Miami, FL, 5University of Miami, Miami, FL

    Background/Purpose: Raynaud’s Phenomenon (RP) is frequently seen in autoimmune conditions, but an autoimmune basis for RP has not been established. Methods: Sera derived from anti-RNP+…
  • Abstract Number: 3005 • 2014 ACR/ARHP Annual Meeting

    Essential Role for Alternately Spliced Tenascin C and TLR4 Signaling in Persistent Organ Fibrosis

    Swati Bhattacharyya1,2, Wenxia Wang1, Luisa Morales-Nebreda3, Katja Lakota3, Robert Lafyatis4, Monique E. Hinchcliff5, GR Scott Budinger3, Zenshiro Tamaki3 and John Varga6, 1Medicine/Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 2Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 3Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, 4Rheumatology, Boston University School of Medicine, Boston, MA, 5Northwestern University, Feinberg School of Medicine, Chicago, IL, 6Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose Transforming growth factor-beta stimulates collagen synthesis and myofibroblast differentiation, and is implicated as a key initiating factor in pathological tissue remodeling in scleroderma. However,…
  • Abstract Number: 3006 • 2014 ACR/ARHP Annual Meeting

    Activation of the Thromboxane A2 Receptor By 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma

    Pei-Suen Tsou1, George Zakhem2, Beatrix Balogh2, M. Asif Amin3, Phillip Campbell4, Gautam Edhayan3, Ray A. Ohara3, Elena Schiopu3, Dinesh Khanna1, Alisa E. Koch2,5 and David A. Fox3, 1University of Michigan Scleroderma Program, Ann Arbor, MI, 2University of Michigan Medical School, Ann Arbor, MI, 3Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 4Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 5Department of Veteran's Affairs and University of Michigan, Ann Arbor, MI

    Background/Purpose: Scleroderma (SSc) is a complex disease characterized by inflammation, vasculopathy, and excessive deposition of extracellular matrix. Various studies have demonstrated a paradoxical increase in…
  • Abstract Number: 3007 • 2014 ACR/ARHP Annual Meeting

    Can Knee Pain be Prevented through Diet and Exercise Among Those at High Risk?  the Look Ahead Study

    Daniel White1, Tuhina Neogi2, W. Jack Rejeski3, Michael Walkup3, Cora E. Lewis4, Michael Nevitt5, Capri Foy3 and David T. Felson2, 1Clinical Epidemiology Training, Boston Univ School of Med, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Wake Forest University, Winston-Salem, NC, 4Preventive Medicine, The University of Alabama at Birmingham, Birmingham, AL, 5Epidemiology and Biostatistics, UCSF, San Francisco, CA

    Background/Purpose: Weight loss combined with exercise is effective for reducing pain and improving function in adults with knee pain.  However, it is not known if…
  • Abstract Number: 3008 • 2014 ACR/ARHP Annual Meeting

    High Prevalence of Subclinical Ultrasonographic Enthesopathy and Synovitis in Patients with Inflammatory Bowel Disease without Clinical Signs or Symptoms of Spondyloarthritis

    Esther Vicente1, Silvia Pérez-Esteban2, María Chaparro3, Francisco Rodríguez-Salvanés4, Lorena Vega4, Santos Castañeda1 and Javier P Gisbert5, 1Rheumatology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, 2Rheumatology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, 3Gastroenterology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, 4Epidemiologic Research Unit, Hospital Universitario de La Princesa, IISP, Madrid, Spain, 5Gastroenterology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain

    Background/Purpose Musculoskeletal manifestations as peripheral arthritis, axial disease and enthesitis are present in 10-62% of Inflammatory Bowel Disease (IBD) patients. Ultrasonography is more sensitive than…
  • Abstract Number: 3009 • 2014 ACR/ARHP Annual Meeting

    Stem Cell Augmentation for Cardiovascular Risk in Rheumatoid Arthritis

    Nidhi Garg1, Ashit Syngle2 and Pawan Krishan1, 1Deptt. of Pharmaceutical Sciences & Drug Research, Punjabi University Patiala, India, Patiala, India, 2Cardio Rheuma, Healing Touch City Clinic, Fortis Multispeciality Hospital, Chandigarh, India

    Background/Purpose: Bone marrow derived stem cells, endothelial progenitor cells (EPCs), protect against atherosclerotic vascular damage by overcoming endothelial damage. However, EPCs are depleted in RA…
  • Abstract Number: 3010 • 2014 ACR/ARHP Annual Meeting

    The Development and Evaluation of a Self-Monitoring and Patient-Initiated Follow-up Service for People with Rheumatoid or Psoriatic Arthritis on Methotrexate

    Hayley McBain1,2, Michael Shipley3, Abigail Olaleye3, Samantha Moore4, Shashi Hirani5 and Stanton Newman6, 1Health Services Research and Management Division, City University London, London, United Kingdom, 2Community Health Newham, East London Foundation Trust, London, United Kingdom, 3University College Hospital London, London, United Kingdom, 4Rheumatology, University College London, London, United Kingdom, 5City University London, London, United Kingdom, 6School of Community & Health Sciences, City University London, London, United Kingdom

    Background/Purpose: Patient-initiated services in rheumatology have been found to be cost-saving without compromising the clinical or psychosocial well-being of patients with rheumatoid arthritis. Self-monitoring is…
  • Abstract Number: 3011 • 2014 ACR/ARHP Annual Meeting

    Ambulatory Gait Analysis in Clinical Practice: Single or Dual Task Conditions?

    Bernard Auvinet1, Claude Touzard2 and Vincent Goëb3, 1Rheumatology Unit, Polyclinic, LAVAL, France, 2Gerontology Unit, Hospital of Laval, LAVAL, France, 3Rheumatology, Amiens University Hospital, Amiens, France

    Background/Purpose Interest in ambulatory gait analysis is increasing thanks to validated gait analysis apparatus dedicated to clinical practice. Such methodology has to be reproducible, sensitive,…
  • Abstract Number: 3012 • 2014 ACR/ARHP Annual Meeting

    Needs Assessment Survey – Evaluation of Sexual Dysfunction Among Patients at a Tertiary Rheumatology Clinic

    Sharon Nesher Peleg1, Ori Elkayam2, Bruria Yahini1 and Jacob N. Ablin3, 1Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, 3Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Background/Purpose Sexual function is a major component of wellbeing and is adversely affected by many disease states. Previous studies have demonstrated various aspects of sexual…
  • Abstract Number: 3013 • 2014 ACR/ARHP Annual Meeting

    The Reserve Capacity Model in Patients with Rheumatoid Arthritis: Understanding the Relationship of Socioeconomic Status, Psychosocial Resources, Mood, and Pain

    Desiree Azizoddin1,2, Taylor Draper1,2, Sarah Ormseth3, Perry M. Nicassio4, Michael R. Irwin4, Michael Weisman5 and Hilary Wilson2, 1Psychology, Loma Linda University, Loma Linda, CA, 2Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, Los Angeles, CA, 3University of California, Los Angeles, Los Angeles, CA, 4Cousins Center for PNI, University of California, Los Angeles, Los Angeles, CA, 5Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA

    The Reserve Capacity Model in Patients with Rheumatoid Arthritis: Understanding the Relationship of Socioeconomic Status, Psychosocial Resources, Mood, and Pain. Background/Purpose: The reserve capacity model…
  • Abstract Number: 3014 • 2014 ACR/ARHP Annual Meeting

    Does the Order or Amount of Risk-Benefit Information Presented Influence patients’ Perceived Value of a Proposed New Medication?

    Liana Fraenkel1, Richard Street2, Harjinder Chowdhary3, Sarah Swift3 and Ellen Peters4, 1Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare Systems, New Haven, CT, 2Texas A&M University, College Station, TX, 3Yale University, New Haven, CT, 4Ohio State University, Columbus, OH

    Background/Purpose: The order and amount of information has been shown to influence risk perceptions related to hazards. In this study we sought to examine whether…
  • Abstract Number: 3015 • 2014 ACR/ARHP Annual Meeting

    Evaluation of the effuc Educational Needs Assessment Tool (ENAT) Focused Patient Education on Health Outcomes in Patients with Rheumatolid Arthritis – a Randomised Controlled Trial

    Adewale O. Adebajo1, Dawn Johnson2, Hardware Bernadette3, Claire Hale4 and Mwidimi Ndosi5, 1Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom, 2Research and Development, Barnsley Hospital NHS Foundation Trust, Barnsley, United Kingdom, 3Research and Development, Barnsley Hospital NHS Foundation Trust, Baarnsley, United Kingdom, 4School of Healthcare, University of Leeds, Leeds, United Kingdom, 5Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom

    Background/Purpose The Educational Needs Assessment Tool (ENAT) is a quick and simple, self completed questionnaire that ensures that patient education is relevant, appropriate and timely for people…
  • Abstract Number: 3016 • 2014 ACR/ARHP Annual Meeting

    Measuring the Impact of an Early RA Support and Education Program Using a Program Evaluation with Patient Identified Outcomes

    Adena Batterman1, Kathryn Klingenstein1, Roberta Horton1, Linda Leff2, Theodore R. Fields3 and Vivian P. Bykerk4, 1Social Work Programs, Hospital for Special Surgery, New York, NY, 2Nursing, Hospital for Special Surgery, New York, NY, 3Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, 4Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose The Early RA Support and Education Program addresses the unique psycho-educational needs of people recently diagnosed (
  • Abstract Number: 2976 • 2014 ACR/ARHP Annual Meeting

    Lung Ultrasound Screening for Interstitial Lung Disease in Rheumatoid Arthritis. Comparison with Usual Detection Algorithms in Clinical Practice

    Marco Antivalle, Michel Chevallard, Michele Battellino, MariaChiara Ditto, Valentina Varisco, Federica Rigamonti, Alessandra Mutti, Fabiola Atzeni, Alberto Batticciotto and Piercarlo Sarzi-Puttini, Rheumatology, L. Sacco University Hospital, Milano, Italy

    Background/Purpose: interstitial lung disease (RA-ILD) is one of the most serious extraarticular complications of rheumatoid arthritis (RA). Presently, it is not clear which is the…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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