ACR Meeting Abstracts

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  • Abstract Number: 291 • 2014 ACR/ARHP Annual Meeting

    Development of a Serious Game Designed for Children with Juvenile Idiopathic Arthritis

    Jean-David Cohen1, Damien Bentayou2, Marcantoine Bernard-Brunel3 and Sonia Tropé4, 1IMMUNO-RHEUMATOLOGY, CHU LAPEYRONIE, MONTPELLIER, France, 2Art Director, CG Artist, PESSAC, France, 3Programmer, CG Artist, PESSAC, France, 4149 avenue du Maine, ANDAR, Paris, France

    Background/Purpose Juvenile Idiopathic Arthritis (JIA) is the most common chronic paediatric rheumatic disease and cause of physical and psychological disability, with family and school consequences.…
  • Abstract Number: 290 • 2014 ACR/ARHP Annual Meeting

    Patterns of Active Joint Involvement in JIA

    Simon W.M. Eng1, Mira Van Veenendaal2, Alan M. Rosenberg3, Kiem Oen4, Quaid Morris1 and Rae S.M. Yeung2, 1University of Toronto, Toronto, ON, Canada, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, 4Pediatrics RR149 Rehab Ctr, University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: JIA encompasses a set of heterogeneous diseases with chronic joint inflammation. Although the ILAR criteria consider joint counts, they do not reflect specific joint…
  • Abstract Number: 289 • 2014 ACR/ARHP Annual Meeting

    Patient-Reported Outcomes in Children with Moderately to Severely Active Polyarticular or Polyarticular-Course Juvenile Idiopathic Arthritis Who Are Prescribed and Treated with Adalimumab

    Gerd Horneff1, Carol A. Wallace2, Pierre Quartier3, Daniel J. Kingsbury4, Kirsten Minden5, Mareike Bereswill6, Vishvas Garg7, Hartmut Kupper6 and Jasmina Kalabic6, 1Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 2University of Washington School of Medicine and Seattle Children's Hospital, Seattle, WA, 3Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 4Randall Children's Hospital at Legacy Emanuel, Portland, OR, 5Kinderklinik der Charite, Otto-Heubner Centrum, Berlin, Germany, 6AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, 7AbbVie Inc., North Chicago, IL

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases of childhood and adolescents, and improvement in health-related quality of life and…
  • Abstract Number: 258 • 2014 ACR/ARHP Annual Meeting

    Pain Characteristics Among Patients with Rheumatoid Arthritis in the Context of Patient-Physician Discordance in Disease Activity Assessments

    John M. Davis III1, Cynthia S. Crowson2, Tim Bongartz1, Clement J. Michet1, Eric L. Matteson1 and Sherine E. Gabriel3, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose Healthcare must be patient-centered to achieve optimal outcomes and quality of life.  From this perspective, it is significant that patients with rheumatoid arthritis (RA)…
  • Abstract Number: 274 • 2014 ACR/ARHP Annual Meeting

    Treatment Prescribing Patterns in a Cohort of Patients with Juvenile Idiopathic Arthritis (JIA). Data from the Childhood Arthritis Prospective Study

    Rebecca Davies1, Roberto Carrasco2, Helen Foster3, Eileen Baildam4, Alice Chieng5, Joyce Davidson6, Yiannis Ioannou7, Lucy R. Wedderburn8, Wendy Thomson9, Kimme L. Hyrich10 and on Behalf Of Childhood Arthritis Prospective Study (CAPS)11, 1Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, 2Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, 3Newcastle University, Newcastle, United Kingdom, 4Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 5Manchester Children's Hospital, Manchester, United Kingdom, 6Royal Hospital for Sick Children, Glasgow, United Kingdom, 7Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom, 8Rheumatology Unit, Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, 9Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, 10Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 11university of Manchester, Manchester, United Kingdom

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is a heterogenous disease, classified according to the International League of Associations for Rheumatology (ILAR). Initial treatment is based largely…
  • Abstract Number: 275 • 2014 ACR/ARHP Annual Meeting

    Environmental Risk Factors and Development of Juvenile Idiopathic Arthritis

    Susan Shenoi1, Kathryn B Whitlock2 and Carol A Wallace3, 1Pediatric Rheumatology, Seattle Childrens Hospital, seattle, WA, 2Core for Biomedical Statistics, Seattle Children's Hosptial, Seattle, WA, 3Pediatric Rheumatology, Seattle Children's Hospital/Univ of Washington, Seattle, WA

    Background/Purpose Juvenile Idiopathic Arthritis (JIA) is a heterogenous group of disorders that is characterized by chronic arthritis in children without known etiology. Environmental factors that…
  • Abstract Number: 273 • 2014 ACR/ARHP Annual Meeting

    Long-Term Safety and Effectiveness of Adalimumab in Children with Moderately to Severely Active Polyarticular or Polyarticular-Course Juvenile Idiopathic Arthritis

    Hermine Brunner1, Nicola Ruperto2, Carol A. Wallace3, Mary Toth4, Ivan Foeldvari5, John Bohnsack6, Diana Milojevic7, C. Egla Rabinovich8, Pavla Vavrincova9, Daniel J. Kingsbury10, Katherine Marzan11, Pierre Quartier12, Kirsten Minden13, Elizabeth Chalom1, Gerd Horneff14, Rolf M. Kuester15, Jason Dare16, Mareike Bereswill17, Hartmut Kupper17, Jasmina Kalabic17, Daniel Lovell18 and Alberto Martini19, 1PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2PRINTO, Genoa, Italy, 3University of Washington School of Medicine and Seattle Children's Hospital, Seattle, WA, 4Akron Children's Hospital, Akron, OH, 5Department of Pediatric Rheumatology, Hamburger Zentrum für Kinder und Jugendrheumatologie, Hamburg, Germany, 6University of Utah, Department of Pediatrics, Salt Lake City, UT, 7Pediatrics, Division of Pediatric Rheumatology, Floating Hospital for Children at Tufts Medical Center, Boston, MA, 8Duke University Medical Center, Durham, NC, 9Fakultni nemocnice v Motole, Praha, Czech Republic, 10Randall Children's Hospital at Legacy Emanuel, Portland, OR, 11Children's Hospital Los Angeles, Los Angeles, CA, 12Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 13Kinderklinik der Charite, Otto-Heubner Centrum, Berlin, Germany, 14Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 15Asklepios Rheumazentrum Hamburg, Hamburg, Germany, 16Arkansas Children’s Hospital, Little Rock, AR, 17AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, 18Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, 19PRINTO-IRCCS, Genova, Italy

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases of childhood. Adalimumab (ADA) is approved for moderate to severe polyarticular JIA…
  • Abstract Number: 272 • 2014 ACR/ARHP Annual Meeting

    Factors Associated with Choice of First Biologic Among Children with Juvenile Idiopathic Arthritis: A Combined Analysis from 2 UK Paediatric Biologic Registers

    Rebecca Davies1, Lianne Kearsley-Fleet1, Eileen Baildam2, Michael W. Beresford3, Helen E. Foster4, Taunton R. Southwood5, Wendy Thomson6, Kimme L. Hyrich7, on Behalf Of The BSPAR Etanercept Cohort Study1 and The Biologics for Children with Rheumatic Diseases (BCRD) study1, 1Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, 2Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 3Alder Hey Children's NHS Foundation Trust Hospital, Institute of Translational Medicine (Child Health), University of Liverpool, Liverpool, United Kingdom, 4Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, 5Institute of Child Health, University of Birmingham and Birmingham Children's Hospital, Birmingham, United Kingdom, 6Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, 7Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom

    Background/Purpose: The management of juvenile idiopathic arthritis (JIA) has been revolutionised by the introduction of biologics such as etanercept (ETN), approved in the UK in…
  • Abstract Number: 271 • 2014 ACR/ARHP Annual Meeting

    Predicting Treatment Response to Etanercept in Juvenile Idiopathic Arthritis: Results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study (BSPAR-ETN)

    Lianne Kearsley-Fleet1, Rebecca Davies1, Mark Lunt1, Taunton R. Southwood2, Kimme L. Hyrich3 and on Behalf Of The BSPAR Etanercept Cohort Study1, 1Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, 2Institute of Child Health, University of Birmingham and Birmingham Children's Hospital, Birmingham, United Kingdom, 3Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom

    Background/Purpose: Etanercept (ETN) is licensed in Europe for use in children with Juvenile Idiopathic Arthritis (JIA) and is routinely prescribed after failure of other DMARDs.…
  • Abstract Number: 270 • 2014 ACR/ARHP Annual Meeting

    Disease Burden Is Comparable in Children with Enthesitis-Related Arthritis and Polyarticular Juvenile Idiopathic Arthritis

    Pierre Quartier1, Jasmina Kalabic2, Zbigniew Zuber3, Kirsten Minden4 and Jaclyn K. Anderson5, 1Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 2AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, 3St. Louis Children’s Hospital, Krakow, Poland, 4Charité Universitätsmedizin Berlin, Berlin, Germany, 5AbbVie Inc., North Chicago, IL

    Background/Purpose: To compare baseline disease characteristics of pediatric patients (pts) with enthesitis-related arthritis (ERA) and polyarticular juvenile idiopathic arthritis (pJIA) from clinical trials with adalimumab…
  • Abstract Number: 269 • 2014 ACR/ARHP Annual Meeting

    Discontinuation of Concomitant Medication for Enthesitis-Related Arthritis during 52 Weeks of Treatment with Adalimumab

    Shirley ML Tse1, Rubén Burgos-Vargas2, Gerd Horneff3, Aileen L. Pangan4, Jasmina Kalabic5, Kristina Unnebrink5 and Jaclyn K. Anderson4, 1Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 2Hospital General de Mexico, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, 3Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 4AbbVie Inc., North Chicago, IL, 5AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

    Background/Purpose: Children with enthesitis-related arthritis (ERA) require medical therapy to control inflammation and restore normal function; however, the use of multiple medications and for longer…
  • Abstract Number: 268 • 2014 ACR/ARHP Annual Meeting

    The Effect of Treatment with Resiniferatoxin and Capsaicin on Dynamic Weight Bearing Measures and Evoked Pain Responses in a Chronic Inflammatory Arthritis Murine Model

    Joseph Bert1, Christopher W. Dorman2, Sandra Frizelle2, Sonia C. Funkenbusch2, Hollis E. Krug3 and Maren L. Mahowald4, 1Internal Medicine, University of Minnesota Internal Medicine Residency, Minneapolis, MN, 2Research, Minneapolis VA Health Care System, Minneapolis, MN, 3Medicine, VA Health Care System, Minneapolis, MN, 4Medicine, University of Minnesota Medical School and Minneapolis VA Health Care System, Minneapolis, MN

    Background/Purpose: Capsaicin (CAP) and Resiniferatoxin (RTX) are vanilloid receptor agonists that when given by intra-articular injections, can normalize Evoked Pain Scores (EPS) and Automated Dynamic…
  • Abstract Number: 266 • 2014 ACR/ARHP Annual Meeting

    An Examination of the Interaction of Opioid Use, Pain, and Depression

    Jenna Goesling1, Matthew Henry2, Stephanie Moser3, Paul Hilliard4, Afton L. Hassett1 and Chad Brummett4, 1Anesthesiology, University of Michigan, Ann Arbor, MI, 2University of Michigan, Ann Arbor, MI, 3Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 4University of Michigan Medical School, Ann Arbor, MI

    Background/Purpose In the past two decades there has been an increase in the use of opioids to treat chronic pain. Despite this trend, there is…
  • Abstract Number: 265 • 2014 ACR/ARHP Annual Meeting

    Prevalence of Medicinal Marijuana Use Among 1000 Rheumatology Patients Attending a Community-Based Rheumatology Clinic: A Prospective Cross-Sectional Study

    Peter A. Ste-Marie1, Yoram Shir1, Emmanouil Rampakakis2, John S. Sampalis2,3, Martin Cohen4, Michael Starr5, Mark A Ware1 and Mary-Ann Fitzcharles6, 1Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, 2JSS Medical Research, Montreal, QC, Canada, 3Jewish General Hospital, McGill University, Montreal, QC, Canada, 4Rheumatology, Mcgill University Health Centre, Montreal, QC, Canada, 5Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 6Rheumatology and Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose:  With a worldwide groundswell of interest in cannabinoids as a possible treatment option for persons with rheumatic diseases, and with few pharmacologic cannabinoid options…
  • Abstract Number: 264 • 2014 ACR/ARHP Annual Meeting

    Efficacy and Safety of Cannabinoid Treatments in the Rheumatic Diseases: A Systematic Review of Randomized Controlled Trials

    Tara Landry1, Mary-Ann Fitzcharles2, Peter A. Ste-Marie3 and Yoram Shir3, 1Montreal General Hospital Medical Library, Mcgill University Health Centre, Montreal, QC, Canada, 2Rheumatology & Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, 3Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: The endocannabinoid system functions to maintain homeostasis in the human body and thereby has effects on modulation of pain and inflammation. Cannabinoid preparations are…
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