Abstracts Archive - Page 2030 of 2607 - ACR Meeting Abstracts

Abstract Number: 2394 • 2015 ACR/ARHP Annual Meeting
B-Flow Imaging of Synovial Tissue in Osteoarthritis
Ralf G. Thiele¹, Allen P. Anandarajah² and Christopher T. Ritchlin³, ¹University of Rochester Medical Center, Rochester, NY, ²Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, ³Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Development of disease modifying medication for osteoarthritis (OA) is desirable, but the target tissue of such treatment remains unclear. We have previously shown that…
Abstract Number: 2395 • 2015 ACR/ARHP Annual Meeting
Predictors of and Longitudinal Factors Associated with Change in Pain, Stiffness and Physical Function over 8 Years in a Midlife Cohort with a Low Prevalence of Knee Osteoarthritis
Hussain Ijaz Khan¹, Andrew McBride², Louisa Chou³, Dawn Aitken⁴, Leigh Blizzard⁵, Changhai Ding⁶, Jean-Pierre Pelletier⁷, Johanne Martel-Pelletier⁸, Flavia Cicuttini⁹ and Graeme Jones⁶, ¹Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ²Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, 7000, Australia, ³Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, ⁴Muscyloskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ⁵Biostatistics, Menzies Institute of Medical Research, Hobart, Australia, ⁶Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁷Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ⁸Pharmacology, Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁹Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Knee Osteoarthritis (OA) is the most common musculoskeletal condition affecting quality of life and was one of the leading causes of the years lived…
Abstract Number: 2396 • 2015 ACR/ARHP Annual Meeting
The Absence of Symptom in Subjects with Advanced Knee OA
Son Kyeong Min¹, Dong-Hyun Kim², Myung Hee Cho³, Dae Gyu Jang³ and Hyun Ah Kim⁴, ¹Chunchun Sacred Heart Hosp, 153, Chunchun, South Korea, ²Deparment of Social and Preventive Medicine, Hallym University College of Medicine, Chunchon, South Korea, ³Department of Statistics, Seoul National University, seoul, South Korea, ⁴Division of Rheumatology, Hanlim University Hospital, Anyang, South Korea
Background/Purpose: Although osteoarthritis(OA) is predominantly considered as a disease of cartilage, articular cartilage is an aneural tissue, and there is a consensus that the association…
Abstract Number: 2397 • 2015 ACR/ARHP Annual Meeting
Detection of Changes in the Serum and Synovial Fluid Levels of Resistin during Flare Ups and Remissions in Primary Knee Osteoarthritis
Hassan Bassiouni, Rheumatology, Al-Azhar University, Cairo, Egypt
Background/Purpose: Resistin is a secreted factor that is elevated following traumatic joint injury, causing matrix degradation and it releases inflammatory cytokines from articular cartilage in…
Abstract Number: 2398 • 2015 ACR/ARHP Annual Meeting
Microrna Biomarker Signature in Osteoarthritis
L. A. Bennett¹, T. Coleman¹, W. Ferrell¹, J. Lockhart², C. Huesa¹, L. Dunning¹, B. Jones³, M. Blyth³, I. B. McInnes¹, M. Kurowska-Stolarska¹ and C. S. Goodyear¹, ¹Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ²The Centre for Musculoskeletal Science, University of the West of Scotland, Paisley, United Kingdom, ³Orthopedic Research Group, Orthopedic Department, Glasgow Royal Infirmary, Glasgow, United Kingdom
Background/Purpose: Our current understanding of osteoarthritis (OA) comes mainly from late stage disease and this is partly due to when patients present with symptoms. It…
Abstract Number: 2399 • 2015 ACR/ARHP Annual Meeting
Baseline Fibulin3 Concentrations Are Associated with Incidence of Clinical Knee OA after 30 Months in Overweight and Obese Women
Jos Runhaar^1,2, Christelle Sanchez^3,4, Sébastien Taralla⁵, Yves Henrotin^4,6 and Sebastia Bierma-Zeinstra^2,7, ¹PO Box 2040, Erasmus MC University Medical Center Rotterdam, Department of General Practice, Rotterdam, Netherlands, ²D-BOARD Consortium, an European Committee FP7 project, Rotterdam, Netherlands, ³University of Liège, Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ⁴D-BOARD Consortium, an European Committee FP7 project, Liege, Belgium, ⁵Artialis SA, Liege, Belgium, ⁶Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, ⁷Erasmus MC University Medical Center Rotterdam, Department of General Practice, Rotterdam, Netherlands
Background/Purpose: Fibulin3 is highly expressed in osteoarthritic cartilage and inhibits angiogenesis and chondrocyte differentiation. It has been demonstrated to interact with the tissue inhibitor of…
Abstract Number: 2400 • 2015 ACR/ARHP Annual Meeting
Association Between Serum Urate and Osteoarthritis Progression in a Non-Obese Cohort
Svetlana Krasnokutsky¹, Mukundan Attur², Jonathan Samuels³, Fangfei Zhang⁴, Meng Chen⁴, Leon Ryback⁵, Steven B. Abramson⁶ and Michael H. Pillinger¹, ¹Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY, ²Rheumatology Research, NYU - Hospital for Joint Diseases, New York, NY, ³Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, ⁴Medicine-Rheumatology, NYU School of Medicine-NYU Hospital for Joint Diseases, New York, NY, ⁵Radiology-Musculoskeletal Radiology, New York University School of Medicine-NYU Hospital for Joint Diseases, New York, NY, ⁶Dept of Rheumatology/Medicine, Hosp for Joint Diseases/NYU, New York, NY
Background/Purpose: We recently reported an association between gout and osteoarthritis (OA) presence and severity, and a possible association between hyperuricemia and OA severity (Howard et…
Abstract Number: 2401 • 2015 ACR/ARHP Annual Meeting
Identification and Characterization of Two Osteoarthritis Phenotypes Applying Two Clinically Tested Biomarkers
Anne C. Bay-Jensen¹, Asger Bihlet², Inger Byrjalsen³, Bente J. Riis², Claus Christiansen², Morten Asser Karsdal¹ and Jeppe Andersen², ¹Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, ²Nordic Bioscience, Herlev, Denmark, ³Research & Development, Nordic Bioscience, Herlev, Denmark
Background/Purpose: The osteoarthritis (OA) population is heterogeneous and it is therefore difficult to target all patients with the same intervention. Thus there is a clinical…
Abstract Number: 2402 • 2015 ACR/ARHP Annual Meeting
Comparison of Synovitis on MRI and Pain in Knee Osteoarthritis Patients with and without Chondrocalcinosis: Data from the Osteoarthritis Initiative (OAI)
Bobby Kwanghoon Han¹, Woojin Kim², Jingbo Niu³, Shristi Basnyat¹, Veniamin Barshay⁴, Charlene Williams⁵, Sharon L. Kolasinski⁶ and David T. Felson³, ¹Division of Rheumatology, Cooper Medical School of Rowan University, Voorhees, NJ, ²Division of Musculoskeletal Radiology, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴Department of Radiology, Cooper Medical School of Rowan University, Camden, NJ, ⁵Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, ⁶Division of Rheumatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: CPPD crystals are frequently deposited in the fibrocartilage of the meniscus and detected radiographically as linear calcification, termed chondrocalcinosis (CC). Several studies have found…
Abstract Number: 2403 • 2015 ACR/ARHP Annual Meeting
Quadriceps Muscle Weakness and the Risk of Knee Cartilage Loss on MRI in a Population-Based Cohort with Knee Pain
Carson Chin¹, Eric C. Sayre², Ali Guermazi³, Savvas Nicolaou⁴, JM Esdaile⁵, Jacek A. Kopec⁶, Anona Thorne⁷, Joel Singer⁷, Hubert Wong⁷ and Jolanda Cibere⁸, ¹Department of Rheumatology, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada, ³Boston University School of Medicine, Boston, MA, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, ⁶School of Population and Public Health, University of British Columbia and ARC, Vancouver, BC, Canada, ⁷Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada, ⁸Rheumatology, University of British Columbia and ARC, Vancouver, BC, Canada
Background/Purpose: The objective of the study was to determine whether clinically assessed baseline quadriceps weakness predicts cartilage loss on MRI after 3 years. Methods: Subjects…
Abstract Number: 2404 • 2015 ACR/ARHP Annual Meeting
Implications of a Positive Patellar Bulge Sign of Knee Joint Effusion in Patients with Osteoarthritis: Association with MRI Signs of Inflammation and with Increased Rate of 5-Year Total Knee Arthroplasty. Data from the Osteoarthritis Initiative
Benjamin Smith¹, David McDougall², Robert G Lambert³, Walter Maksymowych⁴ and Jacob Jaremko³, ¹Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ²Radiology, University of Alberta, Edmonton, AB, Canada, ³Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Most of our understanding of the clinical significance of a knee joint effusion is derived from trauma in young patients, with surprisingly little assessment…
Abstract Number: 2405 • 2015 ACR/ARHP Annual Meeting
Knee Sounds May Predict Osteoarthritis Severity, Symptoms and Function: Pilot Investigation Toward a Novel Dynamic Imaging System
Victoria Manning¹, Costas Yiallourides², Mads Brevadt¹, Alastair Moore², Edouard Auvinet¹, Patrick Naylor² and Justin Cobb¹, ¹Musculoskeletal Lab, Imperial College London, London, United Kingdom, ²Communications and Signal Processing Group, Imperial College London, London, United Kingdom
Background/Purpose: Knee sounds (KS) may provide a low-cost, risk-free means of identifying presence and severity of knee osteoarthritis (KOA). Unlike static imaging, KS during dynamic…
Abstract Number: 2406 • 2015 ACR/ARHP Annual Meeting
The 2011 Fibromyalgia (FM) Criteria Are Helpful in Identifying Central Sensitization in Knee Osteoarthritis
Steven E. Harte¹, Andrew D. Clauw¹, J. Ryan Scott¹, Daniel J. Clauw² and Chad Brummett², ¹Department of Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Both animal and human studies have suggested that both peripheral and central sensitization may occur in nociceptive pain states such as OA. This distinction…
Abstract Number: 2407 • 2015 ACR/ARHP Annual Meeting
Comparison of Knee Osteoarthritis Treatment in the Non-Obese Versus Obese Populations Across Different Medical Specialties
Kelly Forrester¹, Farah Taufiq¹ and Jonathan Samuels^2,3, ¹NYU Langone Medical Center, New York, NY, ²Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, ³Rheumatology, NYU Langone Medical Center, New York, NY
Background/Purpose: Knee osteoarthritis (KOA) in the obese population is underdiagnosed and routinely undertreated, as providers often attribute pain to excess weight without considering articular…
Abstract Number: 2408 • 2015 ACR/ARHP Annual Meeting
The Quality of Community-Based Osteoarthritis Care Can be Improved. Results from a Systematic Review and Meta-Analysis
Kåre Birger Hagen¹, Geir Smedslund², Nina Østerås² and Gro Jamtvedt³, ¹National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology,, Diakonhjemmet Hospital, Oslo, Norway, ³The Norwegian Knowledge Center for the Health Services, Oslo, Norway
Background/Purpose: The burden of osteoarthritis (OA) is substantial and expected to increase because people are getting older and heavier. Health care providers need to monitor…

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