- Abstract Number: 2014 • 2015 ACR/ARHP Annual Meeting - Deficiency of IL-27 Exacerbate Sjögren’s Syndrome through Inhibiting Differentiation of Type 1 Regulatory T CellsBackground/Purpose: Sjögren's Syndrome (SS) is a systemic autoimmune disease characterized by chronic inflammation involving the exocrine glands, particularly the salivary and lacrimal glands. The pathogenesis…
- Abstract Number: 2015 • 2015 ACR/ARHP Annual Meeting - Targeting Non-Canonical NF-Kappa B Signaling Inhibits Angiogenesis in a Novel 3D Model of Rheumatoid Arthritis Synovial AngiogenesisBackground/Purpose: Pathological angiogenesis is a crucial part of disease progression in rheumatoid arthritis (RA) and is often considered the switch from acute to chronic inflammation.…
- Abstract Number: 2016 • 2015 ACR/ARHP Annual Meeting - Functional Tertiary Lymphoid Structures within the Kidneys of Lupus Prone Mice Resembles Lymph Nodes in Gene Expression Profiling Analysis and Are Detected By in Vivo ImagingBackground/Purpose: The formation of tertiary lymphoid structures (TLS) are known to occur during the development of several diseases, including systemic lupus erythematosus (SLE), but in…
- Abstract Number: 2017 • 2015 ACR/ARHP Annual Meeting - DNA Methylation Governs the Ability of Apoptotic Cells to Suppress Inflammatory Arthritis Via Reciprocal Regulation of IL-6 and TGF-BetaBackground/Purpose: Apoptotic cells (AC) have potent anti-inflammatory effects. Injection of apoptotic dendritic cells into mice suppresses the severity of antigen-induced arthritis through increased TGFβ production…
- Abstract Number: 2018 • 2015 ACR/ARHP Annual Meeting - Sodium Chloride Consumption, Together with Smoking, Is Associated with ACPA PositivityBackground/Purpose: Increased salt concentration enhances the production of TH17 cells, which are highly proinflammatory and are pivotal in rheumatoid arthritis (RA) pathogenesis.1, 2 A population-based…
- Abstract Number: 2019 • 2015 ACR/ARHP Annual Meeting - Serum Biomarkers of Inflammatory Arthritis in First Degree Relatives of Patients with Rheumatoid Arthritis and Their Association with Lifestyle Risk FactorsBackground/Purpose: Rheumatoid factor (RF), anti-cyclic citrullinated peptide antibodies (anti-CCP) and C-reactive protein (CRP) are known serum biomarkers of inflammatory arthritis (IA) and have potential predictive…
- Abstract Number: 2020 • 2015 ACR/ARHP Annual Meeting - Elevated BMI and ACPA Together Increase RA Risk and Independently Accelerate Time to RABackground/Purpose: Obesity and anti-citrullinated peptide antibodies (ACPA) are risk factors for RA. We investigated whether body mass index (BMI) and ACPA interact in determining RA…
- Abstract Number: 2021 • 2015 ACR/ARHP Annual Meeting - Omega-3 Fatty Acids Are Associated with a Lower Prevalence of Autoantibody Positivity in HLA-DR Shared Epitope Positive Subjects Who Are at Increased Risk for Future RABackground/Purpose: Studies of fish intake suggest that omega-3 fatty acids (n-3 FAs) could be protective against the development of RA. Previously, we found n-3 FAs…
- Abstract Number: 2022 • 2015 ACR/ARHP Annual Meeting - Adherence to the Dietary Guidelines for Americans and Risk of Developing Rheumatoid Arthritis in Young and Middle-Aged WomenBackground/Purpose: Little is known about the effect of adherence to the Dietary Guidelines for Americans on risk of developing rheumatoid arthritis (RA). The Alternative Healthy…
- Abstract Number: 2023 • 2015 ACR/ARHP Annual Meeting - Breastfeeding, Oral Contraceptive and the Risk of Rheumatoid Arthritis: Results from the Swedish Epidemiological Investigation of RA StudyBackground/Purpose: Breastfeeding (BF) has been associated with both a decreased and an increased risk of developing rheumatoid arthritis (RA). Regarding oral contraceptive (OC) use and…
- Abstract Number: 2024 • 2015 ACR/ARHP Annual Meeting - Replacing Radiographic Sacroiliitis By Structural Lesions on MRI of the Sacroiliac Joints in Two Early Axial Spa Cohorts: What Is the Impact on the Classification of Patients According to the ASAS Axial Spa Criteria?Background/Purpose: Conventional radiography of the sacroiliac joints (X-SI) is the most commonly used imaging technique to detect structural lesions in axial SpondyloArthritis (axSpA). However, a…
- Abstract Number: 2025 • 2015 ACR/ARHP Annual Meeting - Modification of Structural Lesions on Magnetic Resonance Imaging By Etanercept: A 12-Week Randomized Placebo-Controlled TrialBackground/Purpose: Modification of structural lesions by anti-TNF therapy has not been demonstrated in a randomized placebo (PBO)-controlled trial. The Spondyloarthritis Research Consortium of Canada (SPARCC)…
- Abstract Number: 2026 • 2015 ACR/ARHP Annual Meeting - A Novel Technique for Quantifying Synovial Enhancement of Temporomandibular Joints from Mris of Patients with Juvenile Idiopathic ArthritisBackground/Purpose: Juvenile Idiopathic Arthritis (JIA) commonly affects the temporomandibular joints (TMJ) and may cause growth disturbance, functional limitation and facial deformity. Early diagnosis and management…
- Abstract Number: 2027 • 2015 ACR/ARHP Annual Meeting - Development of a Dual Energy Computed Tomography Scoring System for Measurement of Urate Deposition in GoutDevelopment of a Dual Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout Background/Purpose: Dual energy computed tomography (DECT) can visualize urate…
- Abstract Number: 2028 • 2015 ACR/ARHP Annual Meeting - Contribution of 18f-Fluoro-Dexoxyglucose Positron Emission Tomography for the Diagnosis of Polymyalgia Rheumatica: A Controlled StudyBackground/Purpose: Polymyalgia rheumatica (PMR) is a frequent inflammatory condition in elderly people. The place of imaging becomes important for positive and differential diagnosis like malignancy…
