Abstracts Archive - Page 2 of 2616 - ACR Meeting Abstracts

Abstract Number: 001 • 2026 Pediatric Rheumatology Symposium
Longitudinal Cardiovascular Profiles of Youth with Childhood-onset Systemic Lupus Erythematosus
Joyce Chang¹, Gabrielle Alonzi², Michael Ferguson³, Andrea Knight⁴, Jane Newburger⁵, Pamela Weiss⁶, Mary Beth Son² and Karen Costenbader⁷, ¹Boston Children's Hospital, Newton, MA, ²Boston Children's Hospital, Boston, MA, ³Boston Children's Hospital, MA, ⁴Hospital for Sick Children, Toronto, ON, Canada, ⁵Boston Childen's Hospital, Boston, MA, ⁶Childrens Hospital of Philadelphia, Philadelphia, PA, ⁷Brigham and Women's Hospital/ Harvard Medical School, BOSTON, MA
Background/Purpose: The cumulative impact of childhood-onset systemic lupus erythematosus (cSLE) on cardiovascular damage begins at disease onset. We sought to characterize longitudinal cardiovascular profiles of…
Abstract Number: 007 • 2026 Pediatric Rheumatology Symposium
Subtle Signs, Severe Consequences: Clinical profile of infants with giant coronary aneurysms compared to those with normal coronaries. A multicentric retrospective analysis of infants with Kawasaki disease
Abhay Shivpuri¹, manjari Agarwal² and sujata Sawhney³, ¹Neoclinic Children's Hospital, Jaipur, Rajasthan, India, ²Sir Ganga Ram Hospital, NEW DELHI, Delhi, India, ³Sir Ganga Ram Hospital, Sector ³⁷ noida, Uttar Pradesh, India
Background/Purpose: Kawasaki disease (KD) is a systemic medium vessel vasculitis that is predominantly a clinical diagnosis as defined by the American Heart Association (AHA). KD…
Abstract Number: 017 • 2026 Pediatric Rheumatology Symposium
High-Frequency Ultrasound Evaluation Predicts Disease Activity in Juvenile Localized Scleroderma
DANIELA GERENT PETRY PIOTTO¹, Ana Sakamoto², Rosangela Alves³, Gleice Clemente⁴, Melissa Fraga⁵ and Maria Teresa Terreri⁶, ¹Universidade Federal de So Paulo, So Paulo, Brazil, ²Federal University of So Paulo (UNIFESP), So Paulo, Brazil, ³UNIFESP/ EPM, Sao Paulo, Sao Paulo, Brazil, ⁴Universidade Federal de Sao Paulo, So Paulo, Brazil, ⁵Universidade Federal de So Paulo, So Paulo, So Paulo, Brazil, ⁶UNIFESP, So Paulo, So Paulo, Brazil
Background/Purpose: Juvenile localized scleroderma (JLS) poses a diagnostic challenge due to its variable course and absence of standardized imaging biomarkers. High-frequency ultrasound (HFUS) allows objective…
Abstract Number: 026 • 2026 Pediatric Rheumatology Symposium
Treatment strategies for articular flares in JIA patients receiving biologic therapy
Jonatan zalcman, Yoel Levinsky, Liora Harel, Ruth Livny and gil amarilyo, Schneider Children's medical center of Israel
Background/Purpose: Biologic agents form the cornerstone of therapy for Juvenile Idiopathic Arthritis (JIA); however, the optimal management of flares that occur during ongoing treatment remains…
Abstract Number: 018 • 2026 Pediatric Rheumatology Symposium
Abnormal Cortical Grey Matter, White Matter and Subcortical Grey Matter Morphometry is Associated with Disease Features and Quality of Life in Patients with Craniofacial Localized Scleroderma
Diana Valdes Cabrera¹, Subramanian Subramanian², Daniel Glaser³, Elena deRosas⁴, Haley Havrilla⁵, Kathryn Torok⁴ and Andrea Knight⁶, ¹The Hospital for Sick Children, Toronto, ON, Canada, ²UPMC Children’s Hospital of Pittsburgh, ³Yale University School of Medicine, New Haven, CT, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Division of Rheumatology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, ⁶Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Craniofacial localized scleroderma (Cf-LS) is a rare autoimmune disorder that affects face and scalp tissues and is often diagnosed during childhood. Children with Cf-LS…
Abstract Number: 021 • 2026 Pediatric Rheumatology Symposium
Medication Changes and Lung Disease Activity in Systemic JIA: Six-Month Follow-Up of CARRA Registry SJIA-LD Cohort
Grant Schulert¹, Eileen Rife², Mary Ellen Riordan³, Alan Russell⁴, Mei-Sing Ong⁵, Esraa Eloseily⁶, Lexi Auld⁷, Yukiko Kimura⁸, and CARRA Registry SJIA-LD Cohort Investigators ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²University of Alabama Birmingham, Vestavia Hills, AL, ³Hackensack University Medical Center, Westwood, NJ, ⁴Duke Clinical Research Institute, NC, ⁵Boston Children's Hospital, Boston, MA, ⁶UT Southwestern Children's Medical Center, Dallas, TX, ⁷Cincinnati Children's Hospital Medical Center, OH, ⁸Hackensack Meridian School of Medicine, New York, NY
Background/Purpose: Lung disease is a severe and potentially fatal complication of systemic juvenile idiopathic arthritis (SJIA-LD). The Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry…
Abstract Number: 027 • 2026 Pediatric Rheumatology Symposium
An Examination of Brain-age-related Deviations from Normative Neurodevelopmental Trajectory in Children with Childhood-Onset Systemic Lupus Erythematosus
Josephine Machado¹, Diana Valdes Cabrera², Helen Branson³, Adrienne Davis³, Linda Hiraki², Asha Jeyanathan⁴, Deborah Levy², Lawrence Ng⁵, Birgit-Ertl Wagner³ and Andrea Knight⁶, ¹University of Toronto, Woodbridge, ON, Canada, ²The Hospital for Sick Children, Toronto, ON, Canada, ³The Hospital for Sick Children, ⁴Hospital for Sick Children, ON, Canada, ⁵The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada, ⁶Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Neuroinflammation is considered to be a major factor in brain-aging—a decline in the structure and function of the brain with age. Presentation of childhood-onset…
Abstract Number: 016 • 2026 Pediatric Rheumatology Symposium
Still’s Disease Associated Lung Disease: Experience from a Tertiary Italian Centre
Claudia Bracaglia¹, Manuela Pardeo², Matteo Trevisan², Arianna De Matteis², Ivan Caiello³, Giusi Prencipe³ and Fabrizio De Benedetti⁴, ¹Division of Rheumatology Ospedale Pediatrico Bambino Gesu' IRCCS, Roma, Italy, Rome, Rome, Italy, ²Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Lazio, Italy, ³Laboratory of Immuno-Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Lazio, Italy, ⁴Bambino Gesu Children's Hospital, Rome, Rome, Italy
Background/Purpose: Still’s Disease (SD)-associated lung disease (SD-LD) is a severe potentially life-threatening condition characterized by peculiar features. For the rarity of this condition, the experience…
Abstract Number: 014 • 2026 Pediatric Rheumatology Symposium
Bone Microarchitecture Impairment in Juvenile Systemic Lupus Erythematosus Patients: A Comparative Study
BEATRIZ ROSA¹, Melissa Fraga², Ana Sakamoto³, Erica Barbosa⁴, Jade Fernandez⁴, Marcelo Pinheiro⁵ and Maria Teresa Terreri⁶, ¹UNIVERSIDADE FEDERAL DE SO PAULO, So Paulo, Brazil, ²Universidade Federal de So Paulo, So Paulo, So Paulo, Brazil, ³Federal University of So Paulo (UNIFESP), So Paulo, Brazil, ⁴UNIFESP/ EPM, Sao Paulo, Sao Paulo, Brazil, ⁵UNIFESP/ EPM, So Paulo, Brazil, ⁶UNIFESP, So Paulo, So Paulo, Brazil
Background/Purpose: Juvenile Systemic Lupus Erythematosus (jSLE) is a multisystem inflammatory disease frequently associated with bone mass loss. This reduction can be assessed through bone mineral…
Abstract Number: 023 • 2026 Pediatric Rheumatology Symposium
Screening Tools for Spondyloarthropathies among Patients with Inflammatory Bowel Disease: A Scoping Review
Hanul (Erica) Park¹, Ellen Kuenzig², Fatima Mela³, Emaan Awan⁴, Sherry Rohekar⁵, Eileen Crowley¹ and Roberta A Berard⁶, ¹London Children's Hospital, ON, Canada, ²Schulich- University of Western Ontario, ON, Canada, ³Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry at Western University, ON, Canada, ⁴Western University, ON, Canada, ⁵University of Western Ontario - London, London, ON, Canada, ⁶London Health Sciences Centre, London, ON, Canada
Background/Purpose: Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is a systemic chronic inflammatory disease of the gastrointestinal tract where extraintestinal manifestations (EIMs)…
Abstract Number: 005 • 2026 Pediatric Rheumatology Symposium
Magnetic Resonance Enterography Detected Sacroiliitis in Pediatric Crohn’s Disease: A Retrospective Cohort Study
Aaisham Ali¹, Vishal Kalia², Ian Ross², Luke Daichendt³, Julia Sawicka⁴, Michael R Miller⁵, Sarah Wells⁶, Eileen Crowley⁶ and Roberta A Berard⁷, ¹Schulich School of Medicine & Dentistry, Pediatrics, London Health Sciences Centre, London, ON, Canada, ²Department of Medical Imaging, Western University, ³Schulich School of Medicine & Dentistry, Western University, ⁴Western University, ⁵Department of Pediatrics, Children's Hospital, London Health Sciences Centre, ⁶London Children's Hospital, ON, Canada, ⁷London Health Sciences Centre, London, ON, Canada
Background/Purpose: Musculoskeletal (MSK) manifestations are amongst the most common extraintestinal manifestations (EIMs) in pediatric Crohn’s disease (CD). MSK EIMs contribute to reduced quality of life…
Abstract Number: 029 • 2026 Pediatric Rheumatology Symposium
Oral vs Subcutaneous Methotrexate at High Dose for Pediatric Anterior Uveitis
Katie Choi¹ and Melissa Lerman², ¹Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Methotrexate (MTX) is effective and steroid-sparing for pediatric non-infectious anterior uveitis, but whether subcutaneous (SC) achieves control faster than oral (PO) remains unclear. High-dose…
Abstract Number: 024 • 2026 Pediatric Rheumatology Symposium
Therapeutic Plasma Exchange in Pediatric Autoimmune Encephalitis
Ingrid Kattan¹, PAOLA LARA HERERA², ENRIQUE FAUGIER FUENTES³, Candy Leon, MD³, Andrea Sanchez³, VIanca De Leon³ and Enrique Juarez³, ¹HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ, Ciudad de Mxico, Mexico, ²HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ, MEXICO CITY, Mexico, ³HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ
Background/Purpose: Autoimmune encephalitis (AE) is a severe neuroinflammatory disorder mediated by antibodies against neuronal receptors. Therapeutic plasma exchange (TPE) can remove autoantibodies, immune complexes, and…
Abstract Number: 015 • 2026 Pediatric Rheumatology Symposium
Obinutuzumab Induces Histologic Remission And Deep Kidney Parenchymal B-Cell Depletion In Patients With Lupus Nephritis: Exploratory Analyses From The REGENCY Trial
Brad H. Rovin¹, Elsa Martins², Cary D. Austin³, Harini Raghu³, Caleb Chan³, Patrick S. Chang³, Jay P. Garg³, Valeria Alberton⁴, Mittermayer B. Santiago⁵, Gustavo Aroca-Martínez⁶, Fedra I. Palazuelos⁷, Teresa Baczkowska⁸, Jose Alfaro⁹, Jorge Ravelo-Hernandez¹⁰, Richard A. Furie¹¹, Luis F. Pinto¹², Eduardo H. Albeiro¹³, Christopher Larsen¹⁴, Bongin Yoo³, Jennifer Pulley¹⁵, Andrew Thorley³, Thomas Schindler¹⁶, Theodore A. Omachi³, William F. Pendergraft³, Betty Loflin³ and Ana Malvar¹⁷, ¹The Ohio State University, Columbus, OH, ²F. Hoffmann-La Roche Ltd, Basel-Landschaft, Switzerland, ³Genentech, Inc., CA, ⁴Pathology Unit, Fernández Hospital, Buenos Aires, Argentina, ⁵Bahiana School of Medicine and Public Health and UFBA, Federal University of Bahia, and Clínica SER da Bahia, Bahia, Brazil, ⁶Universidad Simón Bolívar y Clínica de la Costa, Barranquilla, Colombia, ⁷Centro de Investigación y Tratamiento Reumatológico S.C, Distrito Federal, Mexico, ⁸Department of Transplantation Medicine, Nephrology and Inernal Medicine, Medical University of Warsaw, Poland, ⁹Instituto Peruano del Hueso y la Articulación, Lima, Peru, ¹⁰Clínica San Juan Bautista, Unidad de Investigación en Reumatología e Inmunología, Lima, Peru, ¹¹Division of Rheumatology, Northwell Health, NY, ¹²Internal Medicine and Rheumatology, Hospital Pablo Tobón Uribe, Colombia, ¹³Sanatorio Allende, Cordoba, Argentina, ¹⁴Arkana Laboratories, Little Rock, AR, ¹⁵Roche Products Ltd, Welwyn Garden City, England, United Kingdom, ¹⁶F. Hoffmann-La Roche Ltd, Basel, Basel-Landschaft, Switzerland, ¹⁷Organización Médica de Investigación, Buenos Aires, Argentina
Background/Purpose: The REGENCY trial (NCT04221477) demonstrated superiority of obinutuzumab (OBI) plus standard therapy (+ST) vs placebo (PBO) +ST in achieving complete renal response (CRR) at…
Abstract Number: 002 • 2026 Pediatric Rheumatology Symposium
Assessing Juvenile Idiopathic Arthritis Healthcare Costs to Advance Value-Based Care
Julia Harris¹, Luke Harris², Kristy Diederich³, Rachel Moran³, Emily Fox², Leslie Favier⁴, Stephanie Quinn³ and ashley cooper², ¹Children's Mercy Kansas City, Overland Park, KS, ²Children's Mercy Kansas City, Kansas City, MO, ³Children's Mercy Kansas City, ⁴Children's Mercy Kansas City, Leawood, KS
Background/Purpose: Despite treatment advances and continued quality improvement efforts, outcomes for our patients with juvenile idiopathic arthritis (JIA) remain suboptimal. To address this challenge, we…

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