- Abstract Number: 1879 • 2015 ACR/ARHP Annual Meeting - Immunosuppressive “Routine”� Treatment of SSc Patients with Limited Cutaneous Involvement and Interstitial Lung DiseaseBackground/Purpose: Interstitial lung disease (ILD) represents one of the most frequent causes of death in systemic sclerosis (SSc) patients. Yet, there are no approved drugs…
- Abstract Number: 1880 • 2015 ACR/ARHP Annual Meeting - Circulating Microparticle Populations May Differentiate Between Connective Tissue Diseases.Background/Purpose: Microparticles (MPs) are membrane-bound vesicles derived from vascular and intravascular cells such as endothelial cells (EMPs) and platelets (PMPs). Circulating MPs levels are altered…
- Abstract Number: 1881 • 2015 ACR/ARHP Annual Meeting - Is the Presence of Esophageal Dilation a Poor Prognostic Factor in Dilated Interstitial Lung Disease Associated with Systemic Sclerosis?Background/Purpose: Several studies have shown that gastroesophageal reflux disease (GERD) is a risk factor in the progression of idiopathic pulmonary fibrosis. In systemic sclerosis (SSc),…
- Abstract Number: 1882 • 2015 ACR/ARHP Annual Meeting - The Predictive Value of Pulmonary Function Tests to Diagnose Interstitial Lung Disease in Adults with Early Diffuse Cutaneous Systemic SclerosisBackground/Purpose: Interstitial lung disease (ILD) is the leading cause of death in patients with systemic sclerosis (SSc). Patients with diffuse cutaneous systemic sclerosis (dcSSc) have…
- Abstract Number: 1883 • 2015 ACR/ARHP Annual Meeting - Association of Myocardial Abnormalities with Disease Characteristic and Brain Natriuretic Peptide (BNP) in Systemic Sclerosis without Cardiac Symptoms As Assessed Using Cardiac Magnetic Resonance Imaging; A Prospective Multi Center StudyBackground/Purpose: In the majority of SSc patients, however, cardiac involvement often remains subclinical. Primary myocardial abnomalities are characterized by fibrosis. Cardiovascular magnetic resonance (CMR) can…
- Abstract Number: 1884 • 2015 ACR/ARHP Annual Meeting - Sensitivity to Change of Nailfold Videocapillaroscopy and Relationship with Disease ProgressionBackground/Purpose: Nailfold videocapillaroscopy (NVC) is a simple, non-invasive and inexpensive imaging technique that allows a detailed assessment of skin microcirculation. Although NVC has face and…
- Abstract Number: 1885 • 2015 ACR/ARHP Annual Meeting - Identification and Clinical Correlations of Rare Autoantibodies in Systemic Sclerosis and Poly/Dermatomyositis PatientsBackground/Purpose: Systemic Sclerosis (SSc), Polymyositis (PM) and Dermatomyositis (DM) are characterized by the presence of serum autoantibodies (autoAbs) which are central in the diagnosis, predicting…
- Abstract Number: 1886 • 2015 ACR/ARHP Annual Meeting - Myocardial Fibrosis Detected By Magnetic Resonance Imaging Is a Predictor of Heart Failure in Systemic Sclerosis (SSc) PatientsBackground/Purpose: In previous studies we showed that prevalence of myocardial fibrosis in SSc patients is 45% and is associated to diffuse disease (dcSSc) and lower…
- Abstract Number: 1887 • 2015 ACR/ARHP Annual Meeting - Deficiency in Micronutrients Is a Frequent Burden in Patients with Systemic SclerosisBackground/Purpose: Micronutrients are essential dietary factors involved in many metabolic processes, including oxidative stress, collagen synthesis and wound healing, which are key aspects of the…
- Abstract Number: 1888 • 2015 ACR/ARHP Annual Meeting - There Is a Need for New Systemic Sclerosis Subset Criteria: A Content Analytic ApproachBackground/Purpose: Systemic sclerosis (SSc) is a family of diseases unified by the presence of immune activation, vasculopathy and fibrosis. The concept of SSc subsets cannot…
- Abstract Number: 1889 • 2015 ACR/ARHP Annual Meeting - Exhaled Nitric Oxide in Systemic Sclerosis Lung DiseaseBackground/Purpose: We evaluated the ability of alveolar and conducting airway nitric oxide (NO) to discriminate between systemic sclerosis (SSc) with and without lung involvement, idiopathic…
- Abstract Number: 1890 • 2015 ACR/ARHP Annual Meeting - Subclinical Biventricular Systolic Function Is Impaired in Patients with Systemic Sclerosis with Real Time 3-D Echpcardiography: 1 Year Follow-up StudyBackground/Purpose: Silent myocardial involvement is associated with poor prognosis in patients with systemic sclerosis (SSc). Here, we aimed to evaluate subclinical left ventricular (LV) and…
- Abstract Number: 1891 • 2015 ACR/ARHP Annual Meeting - Parameters That Predict Worsening of Skin Thickness in Patients with Early Diffuse Cutaneous Systemic SclerosisBackground/Purpose: Skin thickness is a hallmark of systemic sclerosis (SSc), and its progression is associated with poor prognosis. The modified Rodnan total skin thickness score…
- Abstract Number: 1892 • 2015 ACR/ARHP Annual Meeting - Impact of Cardiac Magnetic Resonance Imaging with T1 Mapping and Multi-b Value Diffusion-Weighted Sequences in Systemic Sclerosis for the Assessment of Myocardial Microscopic Fibrosis and PerfusionBackground/Purpose: Systemic sclerosis (SSc) is a complex disease associating vasculopathy, cutaneous and visceral fibrosis, and autoimmunity. Myocardial microscopic fibrosis may occur and potentially lead to…
- Abstract Number: 1893 • 2015 ACR/ARHP Annual Meeting - Relationship Between Vitamin D Levels and Disease Activity in Patients with Systemic SclerosisBackground/Purpose: Low Vitamin D (VD) levels have been observed in several autoimmune diseases, including systemic sclerosis (SSc). Some studies have shown the importance of VD…
