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  • Abstract Number: 1879 • 2015 ACR/ARHP Annual Meeting

    Immunosuppressive “Routine”� Treatment of SSc Patients with Limited Cutaneous Involvement and Interstitial Lung Disease

    Dörte Huscher1, Sabine Adler2, Elise Siegert3, Giuseppina Abignano4, Yannick Allanore5, Jerome Avouac6, Kerstin Becker7, Laszlo Czirjak8,9, Francesco Del Galdo10, Christopher P. Denton11, Oliver Distler12, Ivan Foeldvari13, Beata Garay-Toth14, Serena Guiducci15, Veronika K. Jaeger16, Veronika Lóránd9, Marco Matucci-Cerinic17, Britta Maurer18, Ulf Müller-Ladner19, Svetlana I. Nihtyanova20, Ingo H. Tarner21, Gabriele Valentini22, Serena Vettori23, Ulrich A. Walker24 and Gabriela Riemekasten25, 1Charité-University Hospital and German Rheumatism Research Centre, Berlin, Germany, 2Rheumatology, Immunology, Allergology, University Hospital Bern, Bern, Switzerland, 3Rheumatology and Clinical Immunology, Charité – University Hospital, Berlin, Berlin, Germany, 4Clinical and Experimental Medicine, Second University of Naples, Napoli, Italy, 5Department of Rheumatology A, Paris Descartes University, Cochin Hospital, Paris, France, 6Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, 7Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, 8Rheumatology, Pecs, Hungary, 9Rheumatology and Immunology Medical School, University of Pécs, Pécs, Hungary, 10Scleroderma Group, Leeds Institute of Molecular Medicine, Leeds, United Kingdom, 11Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom, 12Department of Rheumatology, Research of Systemic Autoimmune Diseases, University Hospital Zurich, Zurich, Switzerland, 13Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, 14FESCA, Budapest, Hungary, 15Rheumatology, University of Florence, Florence, Italy, 16Department of Rheumatology, University Hospital Basel, Basel, Switzerland, 17Dept of Medicine/Div of Rheum, University of Florence, Firenze, Italy, 18r, University Hospital Zurich, Zurich, Switzerland, 19Internal Medicine and Rheumatology, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, 20Rheumatology, UCL Division of Medicine, London, United Kingdom, 21Rheumatology and Clinical Immunology, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, 22Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, 23Department of Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, 24Rheumatology, Systemic Sclerosis, Basel, Switzerland, 25Clinic of Rheumatology, University of Luebeck, Lübeck, Germany

    Background/Purpose: Interstitial lung disease (ILD) represents one of the most frequent causes of death in systemic sclerosis (SSc) patients. Yet, there are no approved drugs…
  • Abstract Number: 1880 • 2015 ACR/ARHP Annual Meeting

    Circulating Microparticle Populations May Differentiate Between Connective Tissue Diseases. 

    Eoghan M. McCarthy1,2, Daniel Moreno-Martinez3, Fiona Wilkinson4, Neil J McHugh5,6, Ian N. Bruce7,8, Yvonne Alexander3, John D. Pauling6,9 and Ben Parker7,8, 1The University of Manchester, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, Mmanchester, United Kingdom, 2NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospital NHS Foundation Trust, Manchester, United Kingdom, 3Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, 4School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom, 5Rheumatology, Bath Institute of Rheumatic Diseases, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 6Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom, 7Central Manchester University Hospital NHS Foundation Trust and Manchester Academic Health Science Centre, NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, 8Stopford Building, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 9Upper Borough Walls, Royal National Hospital for Rheumatic Disease, Bath, United Kingdom

     Background/Purpose: Microparticles (MPs) are membrane-bound vesicles derived from vascular and intravascular cells such as endothelial cells (EMPs) and platelets (PMPs). Circulating MPs levels are altered…
  • Abstract Number: 1881 • 2015 ACR/ARHP Annual Meeting

    Is the Presence of Esophageal Dilation a Poor Prognostic Factor in Dilated Interstitial Lung Disease Associated with Systemic Sclerosis?

    Javier Narváez1, Sergi Heredia2, Helena Borrell Paños2, Eulalia Armengol2, Eugenia De Lama3 and Jose Antonio Narvaez3, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Department of Radiology. Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: Several studies have shown that gastroesophageal reflux disease (GERD) is a risk factor in the progression of idiopathic pulmonary fibrosis. In systemic sclerosis (SSc),…
  • Abstract Number: 1882 • 2015 ACR/ARHP Annual Meeting

    The Predictive Value of Pulmonary Function Tests to Diagnose Interstitial Lung Disease in Adults with Early Diffuse Cutaneous Systemic Sclerosis

    Elana J. Bernstein1, Veronica J. Berrocal2, Virginia D. Steen3, Victoria K. Shanmugam4,5, Ami A. Shah6, Monique E. Hinchcliff7, Faye N. Hant8, Jessica K. Gordon9, Tracy M. Frech10, Robyn T. Domsic11, Shervin Assassi12 and Dinesh Khanna13, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Div of Rheumatology, University of Michigan, Ann Arbor, MI, 3Rheumatology, Georgetown University Medical Center, Washington, DC, 4Division of Rheumatology, The George Washington University, Washington, DC, 5Director, Division of Rheumatology, The George Washington University, Washington, DC, 6Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 7Rheumatology, Northwestern University, Chicago, IL, 8Dept of Medicine, Medical University of South Carolina, Charleston, SC, 9Rheumatology, Hospital for Special Surgery, New York, NY, 10Div of Rheumatology, University of Utah, Salt Lake City, UT, 11Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, 12Rheumatology, University of Texas Medical School at Houston, Houston, TX, 13Division of Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Interstitial lung disease (ILD) is the leading cause of death in patients with systemic sclerosis (SSc). Patients with diffuse cutaneous systemic sclerosis (dcSSc) have…
  • Abstract Number: 1883 • 2015 ACR/ARHP Annual Meeting

    Association of Myocardial Abnormalities with  Disease Characteristic and Brain Natriuretic Peptide (BNP) in Systemic Sclerosis without Cardiac Symptoms As Assessed Using Cardiac Magnetic Resonance Imaging; A Prospective Multi Center Study

    Kaita Sugiyama1, Hitomi Kobayashi2, Yasuyuki Kobayashi3, Yosuke Nagasawa1, Natsumi Ikumi4, Takamasa Nozaki5, Hirotake Inomata1, Hidetaka Shiraiwa6, Hiromi Karasawa6, Noboru Kitamura7, Mitsuhiro Iwata5, Yoshihiro Matsukawa6 and Masami Takei5, 1Nihon University School of Medicine, Tokyo, Japan, 2Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 4Nihon University School of Medicine, Shinjuku, Japan, 5Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 6Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 7NIhon University School of Medicine, Tokyo, Japan

    Background/Purpose: In the majority of SSc patients, however, cardiac involvement often remains subclinical. Primary myocardial abnomalities are characterized by fibrosis. Cardiovascular magnetic resonance (CMR) can…
  • Abstract Number: 1884 • 2015 ACR/ARHP Annual Meeting

    Sensitivity to Change of Nailfold Videocapillaroscopy and Relationship with Disease Progression

    Jerome Avouac1, Elide Toniolo2, Gemma Lepri3, Charlotte Hurabielle4, Anaïs Vallet5 and Yannick Allanore6, 1Rheumatology A department and INSERM U1016, Paris Descartes University, Cochin Hospital, Paris, France, 2Rheumatology Unit. Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 3Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Italy, Florence, Italy, 4Rheumatology A department, paris Descartes University, Cochin Hospital, Paris, France, 5Rheumatology A department, Paris Descartes University, Cochin Hospital, Paris, France, 6Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France

    Background/Purpose: Nailfold videocapillaroscopy (NVC) is a simple, non-invasive and inexpensive imaging technique that allows a detailed assessment of skin microcirculation. Although NVC has face and…
  • Abstract Number: 1885 • 2015 ACR/ARHP Annual Meeting

    Identification and Clinical Correlations of Rare Autoantibodies in Systemic Sclerosis and Poly/Dermatomyositis Patients

    Angela Ceribelli1,2, Natasa Isailovic3, Maria De Santis4, Elena Generali1, Marco Massarotti5, Minoru Satoh6 and Carlo Selmi7,8, 1Internal Medicine- Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano (MI), Italy, 2BIOMETRA, University of Milan, Milan, Italy, 3Internal Medicine; Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano (MI), Italy, 4Internal Medicine, Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano (MI), Italy, 5Internal Medicine- Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano (Milan), Italy, 6Department of Clinical Nursing, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan, 7Internal Medicine- Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Italy, 8BIOMETRA Department, University of Milan, Milan, Italy

    Background/Purpose: Systemic Sclerosis (SSc), Polymyositis (PM) and Dermatomyositis (DM) are characterized by the presence of serum autoantibodies (autoAbs) which are central in the diagnosis, predicting…
  • Abstract Number: 1886 • 2015 ACR/ARHP Annual Meeting

    Myocardial Fibrosis Detected By Magnetic Resonance Imaging Is a Predictor of Heart Failure in Systemic Sclerosis (SSc) Patients

    Tatiana Sofia Rodriguez-Reyna1, Martha Morelos-Guzmán2, Pamela Mercado Velazquez3, Pablo Henrandez-Reyes4, Karla Montero-Duarte5, Cynthia Martinez-Reyes6, Carlos Reyes-Utrera6 and Carlos Nunez Alvarez3, 1Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Radiology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, 3Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico, 4Department of Cardiology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, 5Department of Imaging and Radiology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, 6Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico

    Background/Purpose: In previous studies we showed that prevalence of myocardial fibrosis in SSc patients is 45% and is associated to diffuse disease (dcSSc) and lower…
  • Abstract Number: 1887 • 2015 ACR/ARHP Annual Meeting

    Deficiency in Micronutrients Is a Frequent Burden in Patients with Systemic Sclerosis

    Jasmin Laeubli1, Rucsandra Dobrota1, Britta Maurer1, Suzana Jordan2, Benjamin Misselwitz3, Mark Fox3 and Oliver Distler1, 1Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 2Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 3Division of Gastroenterology, University Hospital Zurich, Zurich, Switzerland

    Background/Purpose:  Micronutrients are essential dietary factors involved in many metabolic processes, including oxidative stress, collagen synthesis and wound healing, which are key aspects of the…
  • Abstract Number: 1888 • 2015 ACR/ARHP Annual Meeting

    There Is a Need for New Systemic Sclerosis Subset Criteria: A Content Analytic Approach

    Sindhu Johnson1, Medha Soowamber2, Jaap Fransen3, Dinesh Khanna4, Frank H.J. van den Hoogen5, Murray Baron6, Marco Matucci Cerinic7, Christopher P. Denton8, Thomas A. Medsger Jr.9, Patricia E. Carreira10, Gabriela Riemekasten11, Jorg HW. Distler12, Armando Gabrielli13, Virginia D. Steen14, Lorinda Chung15, Richard Silver16, John Varga17, Ulf Müller-Ladner18, Madelon C. Vonk19, Ulrich A. Walker20, Frank Wollheim21, Ariane L. Herrick22, Daniel E. Furst23, Lazlo Czirjak24, Otylia Kowal-Bielecka25, Francesco Del Galdo26, Maurizio Cutolo27, Nicolas Hunzelmann28, Charles Murray29, Ivan Foeldvari30, Luc Mouthon31, Nemanja Damjanov32, Bashar Kahaleh33, Tracy M. Frech34, Shervin Assassi35, Lesley Ann Saketkoo36 and Janet E. Pope37, 1Toronto Scleroderma Program, Toronto Western Hospital, Mount Sinai Hospital, University of Toronto, University Health Network Pulmonary Hypertension Programme, Toronto, ON, Canada, 2Rheumatology, University of Toronto/ Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, Radboud University Medical Centre, Nijmegen, Netherlands, 4Medicine, University of Michigan, Ann Arbor, MI, 5Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 6Pavillion A, Rm 216, Jewish General Hospital, Montreal, QC, Canada, 7Department of BioMedicine, Division of Rheumatology, Transition Unit, University of Florence, Firenze, Italy, 8Centre for Rheumatology, Royal Free Hospital, London, United Kingdom, 9Medicine/Rheumatology, Univ of Pittsburgh, Pittsburgh, PA, 10Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, 11Rheumatology, Human medicine, BERLIN, Germany, 12Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, 13Clinica Medica, Università Politecnica delle Marche, Ancona, Italy, 14Rheumatology, Georgetown University Medical Center, Washington, DC, 15Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, 16Div Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, 17Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 18Rheumatology, Internal Medicine, Bad Nauheim, Germany, 19Rheumatology, Rheumatology, Nijmegen, Netherlands, 20Rheumatology, Systemic Sclerosis, Basel, Switzerland, 21Rheumatology, Lund University Hospital, Lund, Sweden, 22Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, 23Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 24University of Pécs Medical Center, Pécs, Hungary, 25Department of Rheumatology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland, 26University of Leeds, Leeds, United Kingdom, 27Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, 28Department of Dermatology, University of Cologne, Cologne, Germany, 29Department of Gastroenterology, Royal Free Hospital, London, United Kingdom, 30Rheumatology, Hamburg, Germany, 31Department of Internal Medicine, Department of Internal Medicine, Cochin Hospital, Referent Center for Necrotizing Vasculitis and Systemic Sclerosis, Paris-Descartes University, AP-HP, Paris, France, 32Resavska 69, Institute of Rheumatology, Belgrade, Serbia, 33Medicine/Rheumatology, The University of Toledo, Toledo, OH, 34Div of Rheumatology, University of Utah Medical Ctr, Salt Lake City, UT, 35Rheumatology, University of Texas Medical School at Houston, Houston, TX, 36Tulane University Lung Center, New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 37University of Western Ontario, London, ON, Canada

    Background/Purpose: Systemic sclerosis (SSc) is a family of diseases unified by the presence of immune activation, vasculopathy and fibrosis. The concept of SSc subsets cannot…
  • Abstract Number: 1889 • 2015 ACR/ARHP Annual Meeting

    Exhaled Nitric Oxide in Systemic Sclerosis Lung Disease

    Natalie K. Kozij1, John T. Granton2, Philip E. Silkoff3, John Thenganatt4, Shobha Chakravorty4 and Sindhu R. Johnson5, 1Department of Medicine, University Health Network Pulmonary Hypertension Programme, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada., Toronto, ON, Canada, 2Medicine, Univeristiy Health Network Pulmonary Hypertension Programme, Toronto General Hospital and University of Toronto, Toronto, ON, Canada, 3Medicine, Temple University, Philadelphia, PA, 4Respirology, University Health Network Pulmonary Hypertension Programme, Toronto, ON, Canada, 5Toronto Scleroderma Program, Division of Rheumatology, Toronto Western Hospital, Mount Sinai Hospital, Institue of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada

    Background/Purpose: We evaluated the ability of alveolar and conducting airway nitric oxide (NO) to discriminate between systemic sclerosis (SSc) with and without lung involvement, idiopathic…
  • Abstract Number: 1890 • 2015 ACR/ARHP Annual Meeting

    Subclinical Biventricular Systolic Function Is Impaired in Patients with Systemic Sclerosis with Real Time 3-D Echpcardiography: 1 Year Follow-up Study

    Sule Yavuz1, Taylan Sahin2, Selen Yurdakul2, Neslihan Yilmaz3 and Saide Ertekin4, 1Rheumatology, Istanbul Bilim University, Faculty of Medicine,Department of Rheumatology, Istanbul, Turkey, 2Cardiology, Istanbul Bilim University Dept of Cardiology, Istanbul, Turkey, 3Istanbul Bilim University, Faculty of Medicine, Rheumatology Department, Istanbul, Turkey, 4Cardiology, Istanbul Bilim University, Dept of Cardiology, Istanbul, Turkey

    Background/Purpose: Silent myocardial involvement is associated with poor prognosis in patients with systemic sclerosis (SSc). Here, we aimed to evaluate subclinical left ventricular (LV) and…
  • Abstract Number: 1891 • 2015 ACR/ARHP Annual Meeting

    Parameters That Predict Worsening of Skin Thickness in Patients with Early Diffuse Cutaneous Systemic Sclerosis

    Masataka Kuwana1, Minoru Hasegawa2, Yucihiro Shirai1, Osamu Ishikawa3, Hirahito Endo4, Fumihide Ogawa5, Daisuke Goto6, Shinichi Sato7, Hironobu Ihn8, Yasushi Kawaguchi9 and Kazuhiko Takehara10, 1Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 2Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan, 3Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan, 4Department of Rheumatology, Jusendo General Hospital, Koriyama, Japan, 5Department of Dermatology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan, 6Division of Clinical Immunology, Doctoral Program in Clinical Sciences, University of Tsukuba, Graduate School of Comprehensive Human Sciences, Tsukuba, Japan, 7Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, 8Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 9Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 10Dermatology, Kanazawa University Graduate School of Medical Science, Kanazawa City, Japan

    Background/Purpose: Skin thickness is a hallmark of systemic sclerosis (SSc), and its progression is associated with poor prognosis. The modified Rodnan total skin thickness score…
  • Abstract Number: 1892 • 2015 ACR/ARHP Annual Meeting

    Impact of Cardiac Magnetic Resonance Imaging with T1 Mapping and Multi-b Value Diffusion-Weighted Sequences in Systemic Sclerosis for the Assessment of Myocardial Microscopic Fibrosis and Perfusion

    Benjamin Terrier1, Hervé Gouya2, Alice Berezne1, Alexis Regent3, Pascal Cohen1, Loïc Guillevin4, Claire Le Jeunne5, Paul Legmann2, Olivier Vignaux6 and Luc Mouthon7, 1Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Paris, France, 2AP-HP Cochin Hospital, Department of Radiology B, Paris, France, 3Service de médecine interne, Hôpital Cochin, Paris, France, 4Internal Medicine, Hopital Cochin, Paris, France, 5Department of Internal Medicine, Hotel-Dieu Hospital, AP-HP, Paris, Paris, France, 6Radiology, Cochin University Hospital, Paris, France, 7Department of Internal Medicine, Department of Internal Medicine, Cochin Hospital, Referent Center for Necrotizing Vasculitis and Systemic Sclerosis, Paris-Descartes University, AP-HP, Paris, France

    Background/Purpose: Systemic sclerosis (SSc) is a complex disease associating vasculopathy, cutaneous and visceral fibrosis, and autoimmunity. Myocardial microscopic fibrosis may occur and potentially lead to…
  • Abstract Number: 1893 • 2015 ACR/ARHP Annual Meeting

    Relationship Between Vitamin D Levels and Disease Activity in Patients with Systemic Sclerosis

    Julia Romero1, Amalia Schiel2, Mariana Landa2, María Luisa Díaz3, María Eugenia Lara1, Mariano Rivero4, Marina Khoury5, Mirtha Alonso2 and Juan Carlos Barreira1, 1Rheumatology Service, British Hospital, Buenos Aires, Argentina, 2Central Laboratory, British Hospital, Buenos Aires, Argentina, 3Nuclear Medicine, British Hospital, Buenos Aires, Argentina, 4Rheumatolgy Service, British Hospital, Buenos Aires, Argentina, 5Teaching and Research, British Hospital, Buenos Aires, Argentina

    Background/Purpose: Low Vitamin D (VD) levels have been observed in several autoimmune diseases, including systemic sclerosis (SSc). Some studies have shown the importance of VD…
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