Abstracts Archive - Page 1992 of 2425 - ACR Meeting Abstracts

Abstract Number: 894 • 2014 ACR/ARHP Annual Meeting
Small Fiber Neuropathy in Women with Fibromyalgia. a Clinical-Pathological Correlation Using Confocal Corneal Biomicroscopy
Manuel Ramírez-Fernández¹, Laura-Aline Martinez-Martinez², Angelica Vargas-Guerrero³, Manuel Martínez-Lavín⁴, Everardo Hernandez Quintela¹ and Jorge Velazco-Caspia¹, ¹Asociación para Evitar la Ceguera en México, Mexico City, Mexico, ²Instituto Nacional de Cardiologia, Mexico City, Mexico, ³Rheumatology, Instituto Nacional de Cardiologia, Mexico City, Mexico, ⁴Chief Rheumatology, Instituto Nacional de Cardiologia, Mexico City, Mexico
Background/Purpose: A consistent line of investigation proposes that fibromyalgia is a sympathetically maintained neuropathic pain syndrome (Semin Arthritis Rheum 2000;29:197). This view has been recently reinforced…
Abstract Number: 895 • 2014 ACR/ARHP Annual Meeting
The Fibromyalgia Syndrome and Widespread Pain Frequency in Active Duty U.S. Service Members with Posttraumatic Stress Disorder
Bernard Hildebrand¹, Jay B. Higgs¹, Douglas Williamson², Edna Foa³, Patricia Resick⁴, Jim Mintz², Antoinette Brundige², Kevin Kelly⁵, Adam Borah⁵, Stacey Young-McCaughan², Brett Litz⁶, Elizabeth Hembree³ and Alan Peterson², ¹Rheumatology, San Antonio Military Medical Center, JBSA - Fort Sam Houston, TX, ²The University of Texas Health Science Center at San Antonio, San Antonio, TX, ³University of Pennsylvania, Philadelphia, PA, ⁴Duke University, Durham, NC, ⁵Carl R. Darnall Army Medical Center, Fort Hood, TX, ⁶VA Boston Healthcare System, Boston, MA
Background/Purpose: Posttraumatic stress disorder (PTSD) and pain are common amongst US military service members who have deployed to Iraq and Afghanistan. Studies suggest the co-morbidity…
Abstract Number: 896 • 2014 ACR/ARHP Annual Meeting
Development of Fibromyalgia and Polysymptomatic Distress Definitions in the National Health Interview Survey
Brian Walitt¹, Richard Nahin², Robert S. Katz³, Martin J. Bergman⁴ and Frederick Wolfe⁵, ¹MedStar Health, Washington, DC, ²National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethedsa, MD, ³Rush Medical College, Chicago, IL, ⁴Taylor Hospital, Ridley Park, PA, ⁵National Data Bank for Rheumatic Diseases, Wichita, KS
Background/Purpose: A detailed understanding of fibromyalgia and its symptoms in the US population would be valuable. The National Health Interview Survey (NHIS) is the principal…
Abstract Number: 892 • 2014 ACR/ARHP Annual Meeting
Symptom Increase in Fibromyalgia Is Not Consistent with the Central Sensitization or Central Hyperresponsiveness Hypothesis
Frederick Wolfe¹, Brian T. Walitt², Johannes Rasker³, Robert S. Katz⁴ and Winfried Häuser⁵, ¹National Data Bank for Rheumatic Diseases, Wichita, KS, ²Rheumatology, Washington Hospital Center, Washington, DC, ³Dpt. Psychology, Health and Technology, University Twente, Enschede, Netherlands, ⁴Rush Medical College, Chicago, IL, ⁵Klinikum Saarbrücken, Saarbrücken, Germany
Background/Purpose: The current dominant hypothesis explains fibromyalgia (FM) as a centralized pain state in which the CNS originates or amplifies pain, which is then accompanied…
Abstract Number: 891 • 2014 ACR/ARHP Annual Meeting
Randomized Clinical Trial of Group Vs. Individual Physical Therapy for Knee Osteoarthritis
Kelli D. Allen¹, Dennis Bongiorni², Hayden B. Bosworth³, Cynthia Coffman³, Santanu Datta⁴, David Edelman³, Jennifer H. Lindquist⁵, Eugene Oddone³ and Helen Hoenig⁶, ¹Health Services Research, Durham VA Medical Center and University of North Carolina at Chapel Hill, Durham, NC, ²Durham VA Medical Center, Durham, NC, ³Health Services Research, Durham VA Medical Center and Duke University Medical Center, Durham, NC, ⁴Health Services Reserach, Durham VA Medical Center and Duke University Medical Center, Durham, NC, ⁵Health Services Research, Durham VA Medical Center, Durham, NC, ⁶Durham VA Medical Center and Duke University Medical Center, Durham, NC
Background/Purpose: Physical therapy (PT) is a key component of treatment for knee osteoarthritis (OA). There is a high demand for PT services in many healthcare…
Abstract Number: 890 • 2014 ACR/ARHP Annual Meeting
Test of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) 29-Item Profile in a Large Cohort of Rheumatic Disease Patients
Patricia P. Katz¹, Sofia Pedro² and Kaleb Michaud³, ¹Medicine, University of California, San Francisco, San Francisco, CA, ²1035 N Emporia Ste 288, National Data Bank, Wichita, KS, ³University of Nebraska Medical Center and National Data Bank, Omaha, NE
Background/Purpose: Patient-reported outcomes are routinely used in rheumatology research and clinical care. Yet, often outcomes cannot be compared across studies or diseases because a variety…
Abstract Number: 889 • 2014 ACR/ARHP Annual Meeting
Exercise, Manual Therapy, and Use of Booster Sessions in Physical Therapy for Knee OA: A Multi-Center Randomized Clinical Trial
G Kelley Fitzgerald¹, Julie Fritz², John Childs³, Gerard P. Brennan⁴, Douglas P. Landsittel⁵, Brett Neilson⁶, Alexandra Gil¹ and J. Haxby Abbott⁷, ¹Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Physical Therapy, University of Utah, Salt Lake City, UT, ³US Army-Baylor University, Schertz, TX, ⁴Rehabilitation Services, Intermountain Healthcare, Murray, UT, ⁵Medicine, Biostatistics and Clinical and Translational Science, University of Pittsburgh, Center for Health Care Research Data Center, Pittsburgh, PA, ⁶Henry M. Jackson Foundation, Bethesda, MD, ⁷Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand
Background/Purpose: There is need to improve the magnitude and duration of treatment effects of exercise therapy (ET) for patients with knee osteoarthritis (KOA). There is…
Abstract Number: 888 • 2014 ACR/ARHP Annual Meeting
Annual Medical Care Expenditures Among US Adults with Gout, 2005 – 2011
Miriam G. Cisternas¹, Louise Murphy², David J. Pasta³, Edward H. Yelin⁴ and Charles Helmick⁵, ¹MGC Data Services, Carlsbad, CA, ²Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ³DMA Corporation, Palo Alto, CA, ⁴Arthritis Research Group, University of California, San Francisco, San Francisco, CA, ⁵Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Costs associated with gout are of growing interest due to its increasing prevalence, but quantifying those costs has been hampered by its co-occurrence with…
Abstract Number: 887 • 2014 ACR/ARHP Annual Meeting
Serological and Clinical Characteristics of a Large Collection of Incomplete Lupus Erythematosus Patients
Teresa Aberle¹, Virginia C. Roberts¹, Julie M. Robertson¹, Joel M. Guthridge¹, Kathy L. Sivils², Astrid Rasmussen², David R. Karp³ and Judith James⁴, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Rheumatic Diseases Division, UT Southwestern Medical Center, Dallas, TX, ⁴Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Incomplete lupus (ILE) is defined as a condition in which patients present with signs of systemic autoimmunity and clinical manifestations compatible with systemic lupus…
Abstract Number: 886 • 2014 ACR/ARHP Annual Meeting
Measuring Rheumatoid Arthritis Remission: Which Index of Disease Activity Best Predicts Work Status?
Nancy A. Baker¹, Heather Eng², Juan (June) Feng², Jason Lyons², Yong Gil Hwang³, Kimberly P. Liang⁴ and Larry W. Moreland⁵, ¹Department of Occupational Therapy, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ³Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ⁴Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁵Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Disease remission is the goal of treat-to-target initiatives in rheumatoid arthritis (RA). There are multiple indices to measure disease activity and remission status including…
Abstract Number: 885 • 2014 ACR/ARHP Annual Meeting
A 2-Week Single-Blind, Randomized, 3-Arm Proof of Concept Study of the Effects of Secukinumab (anti-IL17 mAb), Canakinumab (anti-IL-1 b mAb), or Corticosteroids on Initial Disease Activity Scores in Patients with PMR, Followed By an Open-Label Extension to Assess Safety and Effect Duration
Eric L. Matteson¹, Bhaskar Dasgupta², Wolfgang A. Schmidt³, Carlo Salvarani⁴, Nagui Gendi⁵, Mauro Galeazzi⁶, Sylvie Stitah⁷, Yue Li⁸, Marie-Anne Valentin⁹, Bolan Linghu¹⁰ and Stephen J. Oliver⁷, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Rheumatology, Southend University Hospital, Essex, United Kingdom, ³Rheumatology, Immanuel Krankenhaus, Berlin, Germany, ⁴Rheumatology Unit, Arcispedale-Santa-Maria-Nuova, Reggio Emilia, Italy, ⁵Rheumatology, Basildon & Thurroch University Hospitals NHS Trust, Basildon, Essex, United Kingdom, ⁶Sezione di Reumatologia, Università di Siena, Siena, Italy, ⁷Translational Medicine, Novartis Pharma AG, Basel, Switzerland, ⁸IIS, Novartis Pharma AG, Basel, Switzerland, ⁹Biomarker Development, Novartis Pharma AG, Basel, Switzerland, ¹⁰Translational Medicine, Novartis Pharma AG, Cambridge, MA
Background/Purpose To assess the effects of a single dose of secukinumab or canakinumab in patients with new onset, untreated polymyalgia rheumatica (PMR). Methods In this…
Abstract Number: 884 • 2014 ACR/ARHP Annual Meeting
Interleukin 6 Does Not Upregulate Pro Inflammatory Cytokine Expression in an Ex-Vivo Model of Giant Cell Arteritis
Lorraine O'Neill¹, Jennifer McCormick², Wei Gao², Conor Murphy³, Geraldine M. McCarthy⁴, Douglas J. Veale⁵, Ursula Fearon² and Eamonn S. Molloy¹, ¹Rheumatology, St. Vincent's University Hospital, Dublin 4, Ireland, ²Dublin Academic Medical Centre, Translational Rheumatology Research Group, Dublin, Ireland, ³Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland, ⁴Medicine/Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, ⁵Translational Rheumatology Research Group, St. Vincent's University Hospital, Dublin 4, Ireland
Background/Purpose Interleukin 6 (IL 6) is postulated to play a role in the pathogenesis of Giant Cell Arteritis. Several studies have demonstrated increased circulating IL…
Abstract Number: 883 • 2014 ACR/ARHP Annual Meeting
Accuracy of High Resolution MRI of Scalp Arteries for the Diagnosis of Giant Cell Arteritis: Results of a Prospective Study
Maxime Rhéaume¹, Ryan Rebello², Christian Pagnoux³, Simon Carette³, Marie Clements-Baker⁴, Violette Cohen-Hallaleh², David Doucette-Preville², B. Stanley Jackson⁵, Sam Salama⁶, George Ioannidis⁷ and Nader A. Khalidi¹, ¹Division of Rheumatology, St. Joseph’s Hospital, McMaster University, Hamilton, ON, Canada, ²Department of Radiology, St. Joseph’s Hospital, McMaster University, Hamilton, ON, Canada, ³Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ⁴Rheumatology, Queens University, Kingston, ON, Canada, ⁵Department of Surgery, St. Joseph’s Hospital, McMaster University, Hamilton, ON, Canada, ⁶Department of Pathology, St. Joseph’s Hospital, McMaster University, Hamilton, ON, Canada, ⁷St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: Temporal artery biopsy (TAB) remains the gold standard for the diagnosis of giant cell arteritis (GCA). It is invasive and its sensitivity is limited…
Abstract Number: 881 • 2014 ACR/ARHP Annual Meeting
DNA Methylation Analysis of the Temporal Artery Microenvironment Reveals a Robust T Cell Signature and Suggests a Role for TNF-α in Giant Cell Arteritis
Patrick S. Coit¹, Lindsey B. De Lott², Bin Nan³, Victor M. Elner⁴ and Amr H. Sawalha¹, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, ³Department of Biostatistics, University of Michigan, Ann Arbor, MI, ⁴Department of Ophthalmology and Visual Sciences & Department of Pathology, University of Michigan, Ann Arbor, MI
Background/Purpose: Giant cell arteritis (GCA) is a systemic large vessel vasculitis of unknown etiology. A hallmark of GCA is the presence of granulomatous inflammation of…
Abstract Number: 880 • 2014 ACR/ARHP Annual Meeting
An Immunochip Study Confirms a Strong Contribution of HLA Class I and II Genes in the Susceptibility to Giant Cell Arteritis
Francisco David Carmona¹, Sarah Mackie², Jose Ezequiel Martin¹, John Taylor², Augusto Vaglio³, Lara Bossini-Castillo¹, Santos Castañeda⁴, Maria C. Cid⁵, José Hernández-Rodríguez⁶, Roser Solans⁷, Ricardo Blanco⁸, Lorenzo Beretta⁹, Claudio Lunardi¹⁰, Marco A. Cimmino¹¹, Cisca Wijmenga¹², Torsten Witte¹³, Julia Holle¹⁴, Frank Moosig¹⁴, Verena Schönau¹⁵, Andre Franke¹⁶, Øyvind Palm¹⁷, Andreas P. Diamantopoulos¹⁸, Benedicte A. Lie¹⁹, Simon Carette²⁰, David Cuthbertson²¹, Gary S. Hoffman²², Nader A. Khalidi²³, Curry L. Koening²⁴, Carol A. Langford²⁵, Carol McAlear²⁶, Larry Moreland²⁷, Paul A. Monach²⁸, Christian Pagnoux²⁰, Philip Seo²⁹, Antoine G. Sreih³⁰, Kenneth J. Warrington³¹, Steven R. Ytterberg³¹, Colin T. Pease³², Andrew Gough³³, Michael Green³⁴, Lesley Hordon³⁵, Stephen Jarrett³⁶, Richard Watts³⁷, Sarah Levy³⁸, Yusuf Patel³⁹, Sanjeet Kamath⁴⁰, Bhaskar Dasgupta⁴¹, Paul IW. de Bakker⁴², Bobby P.C. Koeleman⁴², Jennifer H. Barrett², Carlo Salvarani⁴³, Peter A. Merkel⁴⁴, Miguel A. Gonzalez-Gay⁸, Ann W. Morgan² and Javier Martin¹, ¹Immunology, Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Armilla (Granada), Spain, ²NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ³Unit of Nephrology, University Hospital of Parma, Parma, Italy, ⁴Rheumatology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, ⁵Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036- Barcelona, Spain, ⁶Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain, ⁷Autoimmune Systemic Diseases Unit, Department of Internal Medicine, Hospital Vall d'Hebron, Autonomous University of Barcelona, Barcelona, Spain, ⁸Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, IFIMAV, Santander, Spain, ⁹Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy, ¹⁰Department of Medicine, Università degli Studi di Verona, Verona, Italy, ¹¹Department of Internal Medicine, Academic Unit of Clinical Rheumatology, University of Genova, Genova, Italy, ¹²Department of Genetics, University Medical Hospital Groningen, University of Groningen, Groningen, Netherlands, ¹³Clinic for Immunology and Rheumatology, Hannover Medical School, Hannover, Germany, ¹⁴Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt, Germany, ¹⁵Department of Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany, ¹⁶Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany, ¹⁷Department of Rheumatology, Oslo University Hospital and University of Oslo, Oslo, Norway, ¹⁸Department of Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, ¹⁹Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo, Norway, ²⁰Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ²¹Department of Biostatistics, University of South Florida, Tampa, FL, ²²Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, ²³Division of Rheumatology, St. Joseph’s Hospital, McMaster University, Hamilton, ON, Canada, ²⁴Division of Rheumatology, University of Utah, Salt Lake City, UT, ²⁵Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, ²⁶Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA, ²⁷Rheumatology & Clinical Immunology, Vasculitis Center, of University of Pittsburgh Medical Center, Pittsburgh, PA, ²⁸Section of Rheumatology, Vasculitis Center, Boston University School of Medicine, Boston, MA, ²⁹Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, ³⁰Medicine/Division of Rheumatology, The University of Pennsylvania, Philadelphia, PA, ³¹Division of Rheumatology, Mayo Clinic, Rochester, MN, ³²Department of Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ³³Department of Rheumatology, Harrogate and District Foundation Trust, Harrogate, United Kingdom, ³⁴Department of Rheumatology, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, ³⁵Department of Rheumatology, Mid Yorkshire Hospitals NHS Trust, Dewsbury, United Kingdom, ³⁶Department of Rheumatology, Mid Yorkshire Hospitals NHS Trust, Wakefield, United Kingdom, ³⁷Department of Rheumatology, Ipswich Hospital NHS Trust, Ipswich, United Kingdom, ³⁸Department of Rheumatology, Croydon Health Service NHS Trust, Croydon, United Kingdom, ³⁹Department of Rheumatology, Hull and East Yorkshire NHS Trust, Hull East Yorkshire, United Kingdom, ⁴⁰Department of Rheumatology, Staffordshire and Stoke-on-Trent Partnership NHS Trust, Staffordshire, United Kingdom, ⁴¹Department of Rheumatology, Southend University Hospital, Essex, United Kingdom, ⁴²Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands, ⁴³Rheumatology Unit, Department of Internal Medicine, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy, ⁴⁴University of Pennsylvania, Philadelphia, PA
Background/Purpose: Giant cell arteritis (GCA) is a chronic autoimmune vasculitis with an important genetic component. We aimed to identify relevant risk loci for GCA predisposition…

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