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  • Abstract Number: 1173 • 2014 ACR/ARHP Annual Meeting

    Magnetic Resonance Imaging of Inflammatory Severity and Cartilage Damage of Finger Joints in Rheumatoid Arthritis

    Dr. Philipp Sewerin1, Dr. Christoph Schleich2, Anja Mueller-Lutz3, Prof. Dr. Benedikt Ostendorf1, Christian Rubbert4, Dr. Christian Buchbender5, Prof. Dr. Matthias Schneider6, Prof. Dr. Gerald Antoch7 and Dr. Falk Miese5, 1Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, 3Dep. for diagnostic and interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 4Univ. Duesseldorf, Düsseldorf, Germany, 5Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 6Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany, 7Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany

    Background/Purpose To assess the association of inflammation severity and cartilage damage measured by delayed gadolinium-enhanced magnetic resonance imaging of the cartilage (dGEMRIC) of metacarpophalangeal (MCP)…
  • Abstract Number: 1174 • 2014 ACR/ARHP Annual Meeting

    Evaluating MRI-Detected Tenosynovitis of the Hand and Wrist in Early Arthritis

    W.P. Nieuwenhuis1, A. Krabben1, W. Stomp2, T. W. J. Huizinga1, D. M. van der Heijde1, J.L Bloem2, M. Reijnierse3 and A.H.M. van der Helm-van Mil1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose Magnetic resonance imaging (MRI) is a sensitive method to detect local inflammation in rheumatoid arthritis (RA), visualizing synovitis, bone marrow edema and tenosynovitis. The…
  • Abstract Number: 1175 • 2014 ACR/ARHP Annual Meeting

    Association of Hand MRI Findings with the Level of Plasma Cytokines in Patients with Newly Diagnosed Rheumatoid Arthritis

    Yasushi Kondo1, Yuko Kaneko1, Hiroaki Sugiura2, Shunsuke Matsumoto2, Naoshi Nishina1, Masataka Kuwana1, Masahiro Jinzaki2 and Tsutomu Takeuchi1, 1Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 2Department of Radiology, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: Magnetic resonance imaging (MRI) is a very useful modality that can directly visualize both inflammatory and structural changes of affected joints in patients with…
  • Abstract Number: 1176 • 2014 ACR/ARHP Annual Meeting

    Feasibility and Clinical Implication of Radiocarpal Cartilage T1ρ MR Imaging in Rheumatoid Arthritis

    Valentina Pedoia1, Favian Su2, Andrew J. Burghardt1, Jonathan Graft3, John B. Imboden3, Mary Nakamura4, Ursula Heilmeier1, Thomas M Link5 and Xiaojuan Li5, 1Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, 2Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, 3Department of Medicine, Division of Rheumatology, UCSF, San Francisco, CA, 4Arthritis/Rheumatology 111-R, SFVAMC/UCSF, San Francisco, CA, 5Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA

     Background/Purpose Rheumatoid arthritic (RA) disease progression and anti-rheumatic treatment efficacy have traditionally been monitored by evaluation of radiographs. However, MRI has emerged as a more…
  • Abstract Number: 1177 • 2014 ACR/ARHP Annual Meeting

    Evaluation of a Simplified Version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) Comprising 5 Joints (RAMRIS5)

    Dr. Philipp Sewerin1, Dr. Christoph Schleich2, Dr. Christian Buchbender3, Dr. Falk Miese3, Dr. Ralph Brinks4, Prof. Dr. Matthias Schneider5, Prof. Dr. Gerald Antoch6 and Prof. Dr. Benedikt Ostendorf1, 1Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, 3Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 4Univ Duesseldorf, Düsseldorf, Germany, 5Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany, 6Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany

    Background/Purpose Semi-quantitative measurement of inflammatory pathologies of the hand in magnetic resonance images (MRI) is a mandatory, but time-consuming task for MRI controlled studies in…
  • Abstract Number: 1178 • 2014 ACR/ARHP Annual Meeting

    Novel Quantification of MRI Provides a More Sensitive Outcome Measure Than Ramris

    Michael A. Bowes1, Gwenael Guillard1, Eleanor Gill1, Graham R. Vincent1, Elizabeth Hensor2, Jane E. Freeston3,4, Edward M. Vital4, P. Bird5, Paul Emery4 and Philip G. Conaghan6, 1Imorphics Ltd, Manchester, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 3Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, 4NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds., United Kingdom, Leeds, United Kingdom, 5Combined Rheumatology Practice, Sydney, Australia, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom

    Background/Purpose  There is increasing need for sensitive, objective outcome measures in rheumatoid arthritis (RA). MRI is more sensitive than clinical examination and X-rays, using a…
  • Abstract Number: 1179 • 2014 ACR/ARHP Annual Meeting

    Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: Sequential Evaluation Using Whole-Body Magnetic Resonance Imaging

    Michihito Kono1, Shinsuke Yasuda1, Kazumasa Ohmura1, Tomoko Fukui1, Sanae Shimamura1, Ikuma Nakagawa1, Atsushi Noguchi1, Haruki Shida1, Toshiyuki Watanabe1, Yuka Shimizu1, Takashi Kurita1, Kenji Oku1, Toshiyuki Bohgaki1, Olga Amengual1, Tetsuya Horita1, Keita Sakamoto2, Tamotsu Kamishima3 and Tatsuya Atsumi1, 1Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 3Hokkaido University, Faculty of Health Science, Sapporo, Japan

    Background/Purpose: Magnetic Resonance Imaging (MRI) has been established as a useful modality to evaluate synovitis, bone edema, and bone erosion in patients with rheumatoid arthritis…
  • Abstract Number: 1180 • 2014 ACR/ARHP Annual Meeting

    Dynamic Magnetic Resonance Imaging in the Assessment of the Response to Certolizumab Pegol in Rheumatoid Arthritis Patients: Results from a Phase IIIb Randomized Study

    Mikkel Østergaard1, Mette Bjørndal Axelsen2, Lennart T.H. Jacobsson3, Christopher Schaufelberger3, Michael Sejer Hansen4, Johannes W.J. Bijlsma5, Anna Dudek6, Maria Rell-Bakalarska7, Fabienne Staelens8, Robert Haake9, Britt Sundman-Engberg10 and Henning Bliddal11, 1Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, 2Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, 3Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 4Department of Rheumatology, Gentofte Hospital, Copenhagen, Denmark, 5Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 6Medica Pro Familia, Warsaw, Poland, 7Rheuma Medicus, Warsaw, Poland, 8UCB Pharma, Brussels, Belgium, 9UCB Pharma, Raleigh, NC, 10UCB Pharma, Stockholm, Sweden, 11The Parker Institute, Department of Rheumatology, Frederiksberg, Denmark

    Background/Purpose Magnetic resonance imaging (MRI) can detect early joint inflammation with high sensitivity, without use of radiation. The MARVELOUS study (NCT01235598), using the OMERACT RA…
  • Abstract Number: 1159 • 2014 ACR/ARHP Annual Meeting

    Long-Term Quality of Life, Productivity Impairment, Disease Severity and Health Care Costs in Relation to Functional Impairment in Ankylosing Spondylitis Patients in the Czech Republic

    Liliana Sedova1,2, Monika Urbanova3, Jiri Stolfa2,3, David Suchy4, Andrea Smrzova5, Tomas Mlcoch6, Jiri Klimes7 and Tomas Dolezal7, 1rheumatology, Institute of Rheumatology, Prague, Czech Republic, 2Clinic of Rheumatology, Charles University Prague, Prague, Czech Republic, 3Inpatients´ Clinic, Institute of Rheumatology Prague, Prague, Czech Republic, 4Department of Clinical Pharmacology, Rheumatology, University hospital Plzen, Plzen, Czech Republic, 53rd internal clinic, University hospital Olomouc, Olomouc, Czech Republic, 6Institute of Health Economics and Technology Assessment, Prague, Dominica, 7Institute of Health Economics and Technology Assessment, Charles University, Prague, Czech Republic

    Background/Purpose To describe the quality-of-life (QoL), productivity impairment, clinical indicators and health care costs in relationship to functional status described by Bath Ankylosing Spondylitis Functional…
  • Abstract Number: 1158 • 2014 ACR/ARHP Annual Meeting

    A Patient Survey Study of Zoledronic Acid Utilization and Factors Associated with Persistence

    Deborah T. Gold1, Stuart L. Silverman2, Benjamin J. Chastek3, Lung-I Cheng4, Alyssa Goolsby Hunter3, John C. White3, Damon Van Voorhis3 and Bradley S. Stolshek4, 1Duke University Medical Center, Durham, NC, 2OMC Clinical Research Center, Beverly Hills, CA, 3Optum Life Sciences, Eden Prairie, MN, 4Amgen, Inc., Thousand Oaks, CA

    Background/Purpose: Persistence with osteoporosis therapies is associated with clinical outcomes.  The goal of this study is to examine patient-reported persistence with zoledronic acid, a once-yearly…
  • Abstract Number: 1157 • 2014 ACR/ARHP Annual Meeting

    Delay in Diagnosis from Onset of Symptoms By More Than One Year in 31% of Patients with Different Rheumatic Diseases in Australia

    Isabel Castrejón1, Kathryn A. Gibson2 and Theodore Pincus1, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Liverpool Hospital, Liverpool, Australia

    Background/Purpose: Early treatment is regarded as critical for optimal clinical outcomes in patients with inflammatory rheumatic diseases. However, delayed diagnosis is recognized in many rheumatic…
  • Abstract Number: 1156 • 2014 ACR/ARHP Annual Meeting

    Satisfaction with Rural Rheumatology Telehealth Service

    Katherine Poulsen1, Lynden Roberts2, Catherine Millen3, Umayal Lakshman3 and Petra Buttner4, 1Rheumatology and General Medicine, Queensland Health, Brisbane, Australia, 2James Cook University, Melbourne, Australia, 3Queensland Health, Mount Isa, Australia, 4James Cook University, Townsville, Australia

    Background/Purpose: To assess patient satisfaction with the rheumatology telemedicine service provided to a rural town in northern Australia. Methods: A prospective, questionnaire-based exploratory study of…
  • Abstract Number: 1155 • 2014 ACR/ARHP Annual Meeting

    Economic Impact of Frequent Gout Flares in a Managed Care Setting

    Robert Jackson1, Aki Shiozawa2, Erin Buysman3, Aylin Altan3, Stephanie Korrer3 and Hyon K. Choi4, 1Global Medical Office, Takeda Pharmaceuticals International, Inc, Deerfield, IL, 2One Takeda Parkway, Takeda Pharmaceuticals International, Inc, Deerfield, IL, 3Health Economics and Outcomes Research, Optum, Eden Prairie, MN, 4Boston University School of Medicine, Boston, MA

    Background/Purpose Gout is the most common inflammatory arthritis in the US. For most patients, excruciatingly painful gout attacks (“flares”) are the major clinical burden of…
  • Abstract Number: 1154 • 2014 ACR/ARHP Annual Meeting

    Increasing Discrepancies Between Physician Assessment of Disease Activity and Patient Global Health in Germany Between 2000 and 2012

    Dörte Huscher1, Katinka Albrecht2, Katja Thiele2, Sascha Bischoff2, Andreas Krause3, Susanna Späthling-Mestekemper4, Siegfried Wassenberg5 and Angela Zink1, 1German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, 2German Rheumatism Research Centre, Berlin, Germany, 3Konigstr. 63, Immanuel Krankenhaus Berlin, Berlin, Germany, 4Praxis für Innere Medizin/Rheumatologie, München, Germany, 5Rheumaklinik, Fachkrankenhaus, Ratingen, Germany

    Background/Purpose We have seen remarkable achievements in disease control (DAS28) in rheumatoid arthritis in the past decade. They were, however, not accompanied to the same…
  • Abstract Number: 1153 • 2014 ACR/ARHP Annual Meeting

    Area of Residence and Socio-Economic Factors Significantly Affect Access to Biological Therapy for Rheumatoid Arthritis Patients in Romania

    Catalin Codreanu1, Corina Mogosan2, Ruxandra Ionescu3, Ioan Ancuta4, Magda Parvu5 and Simona Rednic6, 15 Thomas Masaryk Street, 'Dr. Ion Stoia' Clinical Center of Rheumatic Diseases, Bucharest, Romania, 2'Dr. Ion Stoia' Clinical Center of Rheumatic Diseases, Bucharest, Romania, 3Rheumatology, Sfanta Maria Clinical Hospital, UMF Carol Davila, Bucharest, Romania, 4“Dr. I. Cantacuzino” Hospital, Bucharest, Romania, 5Rheumatology, Colentina Clinical Hospital, Bucuresti, Romania, 6Rheumatology, University of Medicine and Pharmacy, Cluj-Napoca, Romania

    Background/Purpose Clinical trials have proven the efficacy of biological therapy for rheumatoid arthritis (RA) worldwide. However, high costs have set boundaries to their use, especially…
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