Abstracts Archive - Page 1968 of 2607 - ACR Meeting Abstracts

Abstract Number: 1457 • 2015 ACR/ARHP Annual Meeting
An Organ Based Diagnostic Approach to Macrophage Activating Syndrome in Children Demonstrates Impaired Reticuloendothelial System Clearance
King Soon Goh¹, Francesca Minoia², Angelo Ravelli², Randy Q. Cron³ and Bita Shakoory⁴, ¹Rheumatology, Temple University Hospital, Philadelphia, PA, ²Istituto Giannina Gaslini, Genoa, Italy, ³University of Alabama at Birmingham, Birmingham, AL, ⁴Rheumatology, George Washington University, Washington, DC
Background/Purpose: Early recognition and treatment of Macrophage Activating Syndrome (MAS) can improve outcome. Various diagnostic criteria are available to optimize the diagnosis if suspected by…
Abstract Number: 1458 • 2015 ACR/ARHP Annual Meeting
Association of Chronic, Extreme Elevation of Serum IL-18 with the Development of Macrophage Activation Syndrome in a Cohort of Autoinflammatory Disease Patients: A Potential Diagnostic Biomarker?
Scott Canna¹, Adriana Almeida de Jesus², Yan Huang³, Sushanth Gouni¹, Guangpu Shi⁴, Igal Gery⁴ and Raphaela Goldbach-Mansky³, ¹Molecular Immunology and Inflammation Branch, NIAMS/NIH, Bethesda, MD, ²Translational Autoinflammatory Disease Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, ³Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, ⁴National Eye Institute/NIH, Bethesda, MD
Background/Purpose: Macrophage Activation Syndrome (MAS) is a life-threatening systemic inflammatory syndrome that complicates several rheumatic diseases. Current MAS-related serum biomarkers (ferritin, neopterin, CD163, and CD25)…
Abstract Number: 1459 • 2015 ACR/ARHP Annual Meeting
Racial Comparisons of Children with Idiopathic Uveitis: Results from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry
Sheila T. Angeles-Han^1,2,3, Curtis Travers³, Mindy S. Lo⁴, C. Egla Rabinovich⁵, Sampath Prahalad⁶ and and CARRA Registry Investigators, ¹Children's Healthcare of Atlanta, Atlanta, GA, ²Ophthalmology, Emory University School of Medicine, Atlanta, GA, ³Pediatrics, Emory University School of Medicine, Atlanta, GA, ⁴Medicine/Immunology, Children's Hospital Boston, Boston, MA, ⁵Duke University Medical Center, Durham, NC, ⁶Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA
Background/Purpose: Childhood uveitis can lead to poor visual outcomes. Our data from single center studies suggests that non-Hispanic African American children (NHB) with non-inflammatory uveitis…
Abstract Number: 1460 • 2015 ACR/ARHP Annual Meeting
Association of Vitamin D Receptor Polymorphism with Juvenile Idiopathic Arthritis (JIA)
Fernanda Falcini^1,2, Francesca Marini³, Stefano Stagi⁴, Gemma Lepri², Donato Rigante⁵, Marco Matucci-Cerinic² and M. L. Brandi³, ¹Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Firenze, Italy, ²Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Italy, Florence, Italy, ³University of Florence, Dept. of Surgery and Translational Medicine, Florence, Italy, ⁴Pediatric Endocrinology Unit, Anna Meyer Children’s Hospital, University of Florence, Pediatric Endocrinology Unit, Anna Meyer Children’s Hospital, Firenze, Italy, ⁵Istitute of Pediatrics, Università Cattolica del Sacro Cuore, Rome, Italy
Background/Purpose: JIA is the most common chronic arthritis of childhood. Vitamin D is a potential immuno-modulator in many conditions, including autoimmune diseases. Its influence in…
Abstract Number: 1461 • 2015 ACR/ARHP Annual Meeting
Inflammatory Bowel Disease in Children with Systemic Juvenile Idiopathic Arthritis
Emily Fox¹, Joyce Hsu², Elizabeth Chalom^3,4, Sarah Sertial⁵, KT Park⁶, Julia F Simard⁷, Pierre Quartier⁸, Maria Teresa Terreri⁹, Kevin Baszis¹⁰, Charlotte Borocco¹¹, Sampath Prahalad¹², Adam Reinhardt¹³, Dieneke Schonenberg¹⁴, Elizabeth D. Mellins¹⁵ and Devy Zisman¹⁶, ¹Pediatric Rheumatology, Stanford, Palo Alto, CA, ²Pediatric Rheumatology, Stanford University, Palo Alto, CA, ³Pediatrics, St Barnabas Med Center-ACC, Livingston, NJ, ⁴Pediatric Rheumatology, St. Barnabas Medical Center, West Orange, NJ, ⁵Children's Hospital of New Jersey, Livingston, NJ, ⁶Division of Gastroenterology, Stanford University School of Medicine, Stanford, CA, ⁷Division of Epidemiology, Health Research and Policy Department, and Division of Immunology & Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, ⁸Hôpital Necker-Enfants Malades, Paris, France, ⁹Pediatrics, Universidade Federal de Sao Paulo, São Paulo, Brazil, ¹⁰Pediatrics, Division of Rheumatology, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO, ¹¹Necker Hospital for Sick Children, Paris, France, ¹²Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, ¹³Faculty of Physicians of the University of Nebraska Medical Center, College of Medicine, Nebraska, NE, ¹⁴Department of Pediatric Rheumatology and Immunology, Emma Children's Hospital, Academic Medical Center, Amsterdam, Netherlands, ¹⁵Dept of Pediatrics CCSR, Stanford University Med Ctr, Stanford, CA, ¹⁶Rheumatology Unit, Carmel Medical CenterThe Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel, Haifa, Israel
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease accompanied by systemic symptoms including lymphadenopathy, serositis, and hepatosplenomegaly. Recently, we encountered a patient previously…
Abstract Number: 1462 • 2015 ACR/ARHP Annual Meeting
Farber Disease: Important Differential Diagnostic Information for JIA and Other Inflammatory Arthritis Phenotypes Is Revealed By Data from the Largest Clinical Cohort to Date
Alexander Solyom¹, Boris Huegle², Bo Magnusson³, Balahan Makay⁴, Nur Arslan⁵, John Mitchell⁶, Pranoot Tanpaiboon⁷, Norberto Guelbert⁸, Ratna Puri⁹, Lawrence Jung¹⁰, Giedre Grigelioniene¹¹, Karoline Ehlert¹², Michael Beck¹³, Calogera Simonaro¹⁴ and Edward Schuchman¹⁵, ¹Pediatrics, University of Pecs, Pecs, Hungary, ²Pediatric Rheumatology, German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany, ³Pediatric Rheumatology, Karolinska University Hospital, Stockholm, Sweden, ⁴Pediatric Rheumatology, Eylul University, Izmir, Turkey, ⁵Eylul University, Izmir, Turkey, ⁶Pediatric Endocrinology, Montreal Children's Hospital, Montreal, QC, Canada, ⁷Genetics and Metabolism, Children's National Medical Center, Washington, DC, ⁸Metabolic Diseases Section, Children’s Hospital of Cordoba, Cordoba, Argentina, ⁹Medical Genetics, Sir Ganga Ram Hospital, New Delhi, India, ¹⁰Pediatric Rheumatology, Children's National Med Ctr, Washington, DC, ¹¹Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden, ¹²University Medical Center - Greifswald, Greifswald, Germany, ¹³Institute of Human Genetics, University Medical Center - Mainz, Mainz, Germany, ¹⁴Genetics and Genomic Sciences, Icahn School of Medicine at Mt. Sinai, New York, NY, ¹⁵Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
Background/Purpose: Farber disease (Farber lipogranulomatosis; acid ceramidase deficiency) is a rare lysosomal storage disorder resulting from the inherited deficiency of the enzyme acid ceramidase due…
Abstract Number: 1463 • 2015 ACR/ARHP Annual Meeting
Anti-Cyclic Citrullinated Peptide Antibody Subclass Phenotypes in Polyarticular Juvenile Idiopathic Arthritis
Hannah Peckham¹, Lauren Bourke^2,3, Anna Radziszewska⁴, Maria Leandro⁵, Debajit Sen², Geraldine Cambridge⁶ and Yiannis Ioannou^7,8, ¹Adolescent Centre for Rheumatology Research, University College London, London, United Kingdom, ²Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom, ³Centre for Rheumatology Research, University College London, London, United Kingdom, ⁴The Rayne Institute, Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, ⁵Centre for Rheumatology, University College London, London, United Kingdom, ⁶Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, ⁷Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, ⁸Centre for Rheumatology Research, University College Hospital London, London, United Kingdom
Background/Purpose: Raised levels of Rheumatoid Factor (RhF) and antibodies to citrullinated proteins (ACPA), detected in the clinic using combinations of cyclic citrullinated peptides (CCP), are…
Abstract Number: 1464 • 2015 ACR/ARHP Annual Meeting
Assessment of Left Ventricle Functions in Children with Familial Mediterranean Fever with Tissue Doppler and Strain Echocardiography
Fatih Kelesoglu¹, Gafur Dogdu², Remzi Sarikaya³, Adem Atici³, Serra Karaca⁴, Zeynep Sarac⁵, Feyza Tiryaki⁵, Omer Kumas⁵, Zehra Bugra⁶, Sevinc Emre⁷ and Rukiye Omeroglu⁸, ¹Pediatric Rheumatology, Istanbul Medical School, Pediatric Rheumatology, Istanbul, Turkey, ²Pediatric Cardiology, Istanbul Medical School, Pediatric Cardiology, istanbul, Turkey, ³Cardiology, istanbul Medical School, Cardiology, istanbul, Turkey, ⁴Pediatric Rheumatology, istanbul Medical School, Pediatric Cardiology, istanbul, Turkey, ⁵Student, istanbul Medical School, istanbul, Turkey, ⁶cardiology, istanbul Medical School, Cardiology, istanbul, Turkey, ⁷Istanbul Medical School, Pediatric Rheumatology, istanbul, Turkey, ⁸Pediatric Rheumatology, Istanbul Medical School, Pediatric Rheumatology, istanbul, Turkey
Assessment of Left Ventricle Functions in Children with Familial Mediterranean Fever with Tissue Doppler and Strain Echocardiography Background/Purpose: The effects of Familial Mediterranean Fever (FMF)…
Abstract Number: 1465 • 2015 ACR/ARHP Annual Meeting
Musculoskeletal Anomalies in Children with Trisomy 21
charlene foley¹, Orla G killeen¹ and emma Jane macDermott², ¹Our Lady's Children's Hospital Crumlin, National Centre for Paediatric Rheumatology, Dublin, Ireland, ²our Lady's Children's Hospital Crumlin, National Centre for Paediatric Rheumatology, Dublin, Ireland
Background/Purpose: Musculoskeletal complications of Trisomy 21 (T21) are common. Almost all children with T21 have muscle hypotonia and joint laxity. The combination of this ligamentous…
Abstract Number: 1466 • 2015 ACR/ARHP Annual Meeting
Assessment of Transition Readiness in Adolescents and Young Adults with Chronic Health Conditions
Paul Jensen^1,2, Gabrielle Paul³, Stephanie LaCount⁴, Brendan Boyle⁵, Manmohan K. Kamboj⁶ and Stacy P. Ardoin⁷, ¹Rheumatology, Nationwide Children's Hospital, Columbus, OH, ²Medicine, Ohio State University Medical Center, Columbus, OH, ³College of Medicine, Ohio State University, Columbus, OH, ⁴Pediatrics, Nationwide Children's Hospital, Columbus, OH, ⁵Gastroenterology, Nationwide Children's Hospital, Columbus, OH, ⁶Endocrinology, Nationwide Children's Hospital, Columbus, OH, ⁷Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH
Background/Purpose: The transition from pediatric to adult care is a vulnerable period associated with increased morbidity and mortality. Guidelines call for assessing patients’ transition readiness…
Abstract Number: 1467 • 2015 ACR/ARHP Annual Meeting
Health Related Quality of Life Is Reduced in Pediatric Patients with Juvenile Idiopathic Arthritis and Juvenile-Onset Fibromyalgia
Michal Feldon¹, Catherine Donnelly², Hermine I. Brunner³, Anne Louis Johnson¹, Lukasz Itert⁴, Lisa G Rider⁵ and Edward H. Giannini³, ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Internal Medicine, University of Cincinnati, Cincinnati, OH, ³Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Division of Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD
Background/Purpose : A number of validated measures are now available for the evaluation of health related quality of life (HRQOL) in children with rheumatic diseases,…
Abstract Number: 1468 • 2015 ACR/ARHP Annual Meeting
The Proposed Outcome Parameters of the Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC) with Uveitis Disability VAS Score Correspond Significantly with Uveitis “Classicaly Assessed” Uveitis Activity
Ivan Foeldvari¹, Sandra Schenck², Gabriele Simonini³, Cinzia DeLibero⁴, Gabriele Brumm⁵, Kaisu Kotaniemi⁶, Susan Mary Nielsen⁷, Regitze Bangsgaard⁷, Irene Pontikaki⁸, Valeria Maria Gerloni⁸, Elisabetta Miserocchi⁹, Vasco Miranda¹⁰, Margarida Guedes¹¹, Sheila T. Angeles-Han¹², Steven Yeh¹³, Jordi Anton¹⁴, Rosa Bou Torrent¹⁵, Carmen García de Vicuña¹⁶, Martina Niewerth¹⁷ and Arnd Heiligenhaus¹⁸, ¹Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, ²Deutsches Rheuma-Forschungszentrum, Berlin, Germany, ³Pediatric Rheumatology, Pediatric Rheumatology Unit, Anna Meyer Children's Hospital-University of Florence, Firenze, Italy, ⁴Ophthalmology Unit, Anna Meyer Children's Hospital, Florence, Italy, ⁵Klinik und Polyklinikum für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany, ⁶Ophthalmology Department, Rheumatism Foundation Hospital, Heinola, Finland, ⁷Rigshospitalet, Copenhagen, Denmark, ⁸Dipartimento di Reumatologia, Università di Milano - Istituto Gaetano Pini, Milano, Italy, ⁹Department of Ophthalmology, Scientific Institute San Raffaele, University Vita-Salute, Milan, Italy, ¹⁰Centro Hospitalar do Porto, Porto, Portugal, ¹¹Hospital de Santo António - Centro Hospitalar do Porto, Porto, Portugal, ¹²Pediatrics, Emory Children's Center, Atlanta, GA, ¹³Ophthalmology, Emory University School of Medicine, Atlanta, GA, ¹⁴Unitat de Reumatologia Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain, ¹⁵Pediatrics Department, Pediatric Rheumatology Unit, Universitat de Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain, ¹⁶Universitat de Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain, ¹⁷Epidemiology, German Rheumatism Research Centre, Berlin, Germany, ¹⁸Department of Ophthalmology at St. Franziskus Hospital Muenster, University of Duisberg-Essen, Muenster, Germany
Background/Purpose: Juvenile idiopathic arthritis (JIA) associated uveitis is one of the most severe comorbidities of JIA and occurs in around 10% of JIA patients. There…
Abstract Number: 1469 • 2015 ACR/ARHP Annual Meeting
A Comparison of Pain and Disability, and Their Association Between Juvenile Primary Fibromyalgia Syndrome and Pediatric Rheumatic Diseases: Results from the Childhood Arthritis and Rheumatology Research Alliance Registry
Jennifer E. Weiss¹ and Mark Connelly², ¹Hackensack Univ Med Ctr, Hackensack, NJ, ²Psychology, University of Kansas Medical Center, Kansas City, KS
Background/Purpose: We aim to determine the extent to which pain severity differs between patients with JPFS and other rheumatic diseases and if the degree of…
Abstract Number: 1470 • 2015 ACR/ARHP Annual Meeting
A Population-Based Study of Outcomes of Patients with Juvenile Idiopathic Arthritis (JIA) Compared to Non-JIA Subjects
Megan L. Krause¹, J.A. Zamora-Legoff², Cynthia S. Crowson³, Thomas Mason II¹, Theresa Wampler Muskardin² and Eric L. Matteson⁴, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Division of Rheumatology, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: The impact of juvenile idiopathic arthritis (JIA) is not confined to joint involvement in children but rather widespread effects extending to adulthood. This study…
Abstract Number: 1471 • 2015 ACR/ARHP Annual Meeting
Phenotypic Differences Between HLA-B27 Positive and Negative Children with Enthesitis-Related Arthritis
Sabrina Gmuca¹, Timothy Brandon², Rui Xiao³, Ilaria Pagnini⁴, Tracey B. Wright⁵, Timothy Beukelman⁶, Esi Morgan-DeWitt⁷ and Pamela F. Weiss⁸, ¹Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, ²Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ⁴Department of Paediatrics, University of Florence and Anna Meyer Children's Hospital, Florence, Italy, Florence, Italy, ⁵Pediatrics/Rheumatology, UT Southwestern Medical Center, Dallas, TX, ⁶Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁷Pediatric rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁸Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: The association of HLA-B27 with spondyloarthritis is well-established. Under the International League of Associations for Rheumatology (ILAR) criteria most children with spondyloarthritis are classified…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].