Abstract Number: 1244 • 2014 ACR/ARHP Annual Meeting
The Prevalence of Malignancy in Adult-Onset Still’s Disease
Background/Purpose: Adult-onset Still's disease (AOSD) is a systemic inflammatory disease of unknown etiology. It is characterized by high fever, evanescent salmon-colored rash, sore throat, liver…Abstract Number: 1243 • 2014 ACR/ARHP Annual Meeting
Macrophage Activation Syndrome Complicating Adult Onset Still’s Disease – Single Center Experience and Literature Review
Background/Purpose: Hemophagocytic lymphohistiocytosis (HLH) is a life threatening complication typically associated with hematologic malignancies and infections. HLH, also referred to as macrophage activation syndrome (MAS),…Abstract Number: 1242 • 2014 ACR/ARHP Annual Meeting
Switching Biologic Agents in Refractory Adult-Onset Still’s Disease: Efficacy and Safety in a Cohort of 20 Patients at a Single Referral Center
Background/Purpose No data is available on the long-term clinical outcome of Adult-Onset Still's Disease (AOSD) patients treated with biological drugs, nor on the efficacy and…Abstract Number: 1241 • 2014 ACR/ARHP Annual Meeting
Efficacy of Tocilizumab Therapy in Korean Patients with Adults Onset Still’s Disease: Multicenter Retrospective Study of 20 Cases
Background/Purpose Adult onset Still’s disease (AOSD) is a rare inflammatory disorder of unknown etiology. Refractory cases to conventional therapy require biologic agents. Although IL-1 targeting…Abstract Number: 1260 • 2014 ACR/ARHP Annual Meeting
The Early Use of Cyclosporine Is Beneficial for Long-Term Prognosis in Patients of Polymyositis/Dermatomyositis-Associated Interstitial Lung Disease with Anti- Synthetase Antibodies
Background/Purpose: Interstitial lung disesases (ILD) is the most common cause of mortality in polymyosotis (PM) and dermatomyositis (DM). Cyclosporine had been reported to improve clinical…Abstract Number: 1259 • 2014 ACR/ARHP Annual Meeting
A Multi-Center Study for Validation of a New Assay for Anti-Melanoma Differentiation-Associated Gene 5 (MDA5) Autoantibody
Background/Purpose Anti-Melanoma Differentiation-Associated Gene 5 (MDA5) antibody is found specifically in patients with dermatomyositis (DM). This autoantibody is associated with clinically amyopathic DM (CADM) and…Abstract Number: 1258 • 2014 ACR/ARHP Annual Meeting
Enzyme-Linked Immunosorbent Assays for Detection of Anti-Transcriptional Intermediary Factor-1 Gamma and Anti-Mi-2 Autoantibodies in Dermatomyositis: Utility and Crossreactivity
Background/Purpose Anti-transcriptional intermediary factor 1 (TIF-1) and anti-Mi-2 antibodies (Abs) are myositis-specific autoantibodies (MSA) selectively detected in dernatomyositis (DM) patients. Anti-TIF-1 Ab is frequently found…Abstract Number: 1256 • 2014 ACR/ARHP Annual Meeting
Clinical and Temporal Characterization of Anti-Jo-1 Positive Anti-Synthetase Syndrome: Preliminary Results of an International Multicentre Study
Background/Purpose: anti Jo-1 antibodies are the main marker of the antisynthetase syndrome (As), a connective tissue disease chiefly characterized by arthritis (A), myositis (M) and…Abstract Number: 1257 • 2014 ACR/ARHP Annual Meeting
A New Multianalyte Assay for Detection of Dermatomyositis-Specific Autoantibodies Undetectable By Commercially Available Immunoassays
Background/Purpose: The disease expression of dermatomyositis (DM) is highly variable among patients, ranging form those with severe muscle weakness in the absence of internal organ…Abstract Number: 1255 • 2014 ACR/ARHP Annual Meeting
Pathogenic Role of Tyrosyl–Transfer RNA Synthetase in Anti-Synthetase Syndrome
Background/Purpose : Autoantibodies directed against the aminoacyl transfer RNA (tRNA) synthetases are associated with myositis, arthritis, Raynaud’s phenomenon, mechanic’s hands, fever, and interstitial lung disease,…Abstract Number: 1254 • 2014 ACR/ARHP Annual Meeting
Anakinra for the Management of Resistant Idiopathic Recurrent Pericarditis in Adults
Background/Purpose Recurrent idiopathic pericarditis is currently considered as an auto-inflammatory disorder which is frequently either resistant to standard therapy (with NSAIDs, colchicine or corticosteroids-CS) or…Abstract Number: 1253 • 2014 ACR/ARHP Annual Meeting
Anakinra – a Promising New Therapy for Idiopathic Recurrent Pericarditis
Background/Purpose Idiopathic recurrent pericarditis (IRP) is a debilitating condition that can be recalcitrant to conventional therapy. Some patients develop steroid dependency with the attendant risks…Abstract Number: 1252 • 2014 ACR/ARHP Annual Meeting
Intravenous Methylprednisolone Pulse Therapy in Severe Inflammatory Eye Disease. a Multicenter Study
Intravenous methylprednisolone pulse therapy in severe inflammatory eye disease. A Multicenter Study.Background/Purpose Treatment with high-dose intravenous methylprednisolone (IVMP) pulse therapy has proved to be effective…Abstract Number: 1251 • 2014 ACR/ARHP Annual Meeting
Efficacy of Certolizumab in Patients with Refractory Uveitis to Other Biologic Therapy. Study of 7 Cases
Background/Purpose Anti-TNF-α therapy may be useful in cases of uveitis refractory to standard synthetic immunosuppressive drugs. Infliximab (IFX) and adalimumab (ADA) are the biologic agents…Abstract Number: 1250 • 2014 ACR/ARHP Annual Meeting
Golimumab As an Alternative Therapy in Patients with Uveitis Refractory to Other Anti-TNFα Drugs. Multicenter Study of 29 Cases
Background/Purpose To evaluate the clinical response and safety of golimumab (GLM) in a series of patients with non-infectious uveitis refractory to other anti-TNFα drugs.Methods Multicenter study of…