Abstracts Archive - Page 1959 of 2425 - ACR Meeting Abstracts

Abstract Number: 1391 • 2014 ACR/ARHP Annual Meeting
Weight Loss and Risk of Death in Rheumatoid Arthritis
Joshua Baker¹, Erica Billig², Grant W. Cannon³, Liron Caplan⁴, Vikas Majithia⁵ and Ted R. Mikuls⁶, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁴Div of Rheumatology, Denver VA and Univ of Colorado School of Medicine, Aurora, CO, ⁵Div of Rheumatology, University of Mississippi Medical Center, Jackson, MS, ⁶Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose Low body mass index (BMI) has been linked to greater mortality among patients with Rheumatoid Arthritis (RA). Weight loss has also been associated with…
Abstract Number: 1390 • 2014 ACR/ARHP Annual Meeting
Heterogeneity in Cardiovascular Risk Factors, Event Rates and RA Disease Characteristics Among Patients with Rheumatoid Arthritis Across 10 Countries – Implications for CV Risk Assessment
Atacc-RA Collaborative Group, Division of Rheumatology, Mayo Clinic, Rochester, MN; Diakonhjemmet hospital, Oslo, Norway; Dudley Group NHS Foundation Trust, West Midlands, United Kingdom; Radboud University Medical Center, Nijmegen, Netherlands; University of Umeå, Umeå, Sweden; University of Athens, Athens, Greece; Harbor UCLA Medical Center, Torrance, CA; Harvard Medical School Brigham and Women's Hospital, Boston, MA; Hospital Universitario Marques de Valdecilla, Santander, Spain; School of Physiology, Faculty of Health Sciences, Witwatersrand University, Johannesburg, South Africa; University of Manitoba, Winnipeg, MB, Canada; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubir, México City, Mexico; Hospital Medisch Spectrum Twente, Enschede, Netherlands
Background/Purpose Patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease (CVD). CVD risk scores for the general population do not accurately predict…
Abstract Number: 1389 • 2014 ACR/ARHP Annual Meeting
Osteophytes Increase the Ambiguity of Clinical Evaluation of Joint Swelling in Rheumatoid Arthritis
Peter Mandl¹, Paul Studenic², Gabriela Supp³, Tanja A. Stamm⁴, Martina Sadlonova⁵, Michaela Ernst⁵, Stefanie Haider⁵, Daniel Aletaha³ and Josef Smolen³, ¹Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Rheumatology, Medical University of Vienna, Vienna, Austria, ⁵Medical University of Vienna, Vienna, Austria
Background/Purpose: It is recommended that a joint be classified as clinically swollen if this swelling is beyond doubt. However in clinical practice the evaluation of…
Abstract Number: 1388 • 2014 ACR/ARHP Annual Meeting
Prevalence and Predictive Factors of Drug-Free and Sustained Remission in Patients with Early Arthritis
Margarita Landi¹, Christian A. Waimann², Gustavo Citera³, O Cerda⁴, Federico Ceccatto⁵, Sergio Paira⁶, Francisco Caeiro⁷, Lucila Marino⁸, M Mamani⁹, Anastasia Secco⁹, G Crespo⁹, AC Alvarez¹⁰, Maria Haye Salinas⁷, A Alvarellos¹¹, Javier Rosa¹², Valeria Scaglioni¹³, Enrique R. Soriano¹⁴, Josefina Marcos¹⁵, Mercedes García¹⁵, A Salas¹⁵, Alejandro Martinez¹⁶, Rafael Chaparro del Moral¹⁷, Oscar Luis Rillo¹⁷, Horacio Berman¹⁸, Alberto Berman¹⁸, Francisco Colombres¹⁸, Edson Veloso¹⁹, Ricardo V. Juárez²⁰, Maria Elena Crespo²¹, Ana Quinteros²², M Leal²², Gabriela Salvatierra²³, C Ledesma²³, Mónica P. Sacnun²⁴, R Quintana²⁵ and Marcelo Abdala²⁶, ¹Rheumatology, Instituto Rehabilitacion Psicofisica, Buenos Aires, Argentina, ²Rheumatology, Hospital Olavarria, Olavarria, Argentina, ³Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Rheumatology, Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, ⁵Rheumatology, Hospital Jose María Cullen, Santa Fé, Argentina, ⁶Section of Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, ⁷Reumatología, Hospital Privado de Córdoba, Córdoba, Argentina, ⁸Rheumathology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ⁹Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ¹⁰Hospital Privado Centro Médico de, Córdoba, Argentina, ¹¹Rheumatology, Hospital Privado Centro Medico De Córdoba, Cordoba, Argentina, ¹²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹³Rheumatology Unit, Internal Medical Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, ¹⁴Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, ¹⁵HIGA San Martín, La Plata, Argentina, ¹⁶Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, ¹⁷Rheumatology Section, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, ¹⁸Centro Medico Privado de Reumatologia, Tucumán, Argentina, ¹⁹Sanatorio y Universidad Adventista Del Plata, Entre Rios, Argentina, ²⁰Rheumatology Section, Hospital Señor del Milagro, Salta, Argentina, ²¹Hospital Señor Del Milagro, Salta, Argentina, ²²Centro Integral de Reumatología, Tucumán, Argentina, ²³Instituto Provincial De Rehabilitación Integral, Stgo. del Estero, Argentina, ²⁴Hospital Provincial, Rosario, Argentina, ²⁵Hospital provincial, Rosario, Argentina, ²⁶Hospital Provincial del Centenario, Santa Fe, Argentina
Background/Purpose : Early and sustained remission has become the ultimate goal in early arthritis patients. The aim of our study was to estimate the prevalence…
Abstract Number: 1387 • 2014 ACR/ARHP Annual Meeting
Radiographic Progression Differs Between Trajectory Clusters Defined By DAS28 Scores in Early Rheumatoid Arthritis
Cheryl Barnabe¹, Ye Sun², Gilles Boire³, Carol Hitchon⁴, Edward C. Keystone⁵, J. Carter Thorne⁶, Boulos Haraoui⁷, Jeffrey R. Curtis⁸, Désirée van der Heijde⁹, Diane Tin¹⁰, Janet E. Pope¹¹ and Vivian P. Bykerk¹², ¹Division of Rheumatology, University of Calgary, Calgary, AB, Canada, ²Mount Sinai Hospital, Toronto, ON, Canada, ³Rheumatology Division, CHUS - Sherbrooke University, Sherbrooke, QC, Canada, ⁴Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ⁵Medicine, University of Toronto, Toronto, ON, Canada, ⁶Southlake Regional Health Centre, Newmarket, Newmarket, ON, Canada, ⁷Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, ⁸The University of Alabama at Birmingham, Birmingham, AL, ⁹Rheumatology, Leiden University Medical Ctr, Leiden, Netherlands, ¹⁰The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹Medicine, Western University, London, ON, Canada, ¹²Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Group-based trajectory modeling defines clusters of individuals in observed data with similar disease trajectories. We have previously defined five distinct trajectories in early rheumatoid…
Abstract Number: 1386 • 2014 ACR/ARHP Annual Meeting
Disease Flares during 10 Year Follow-up in Patients with Rheumatoid Arthritis Are Associated with Joint Damage Progression and Disability
I.M. Markusse¹, L. Dirven², Y.P. Goekoop-Ruiterman³, P.a. van der Lubbe⁴, A.J. Peeters⁵, P.J.S.M. Kerstens⁶, W.F. Lems^7,8, T.W.J. Huizinga² and C.F. Allaart², ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, HAGA hospital, The Hague, Netherlands, ⁴Rheumatology, Vlietland Hospital, Schiedam, Netherlands, ⁵Rheumatology, Reinier de Graaf Gasthuis, Delft, Netherlands, ⁶Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ⁷Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ⁸Rheumatology, VU Medical Center, Amsterdam, Netherlands
Background/Purpose: Disease flares frequently occur in patients with rheumatoid arthritis (RA). It has been suggested that these may spontaneously remit, in which case targeted treatment…
Abstract Number: 1385 • 2014 ACR/ARHP Annual Meeting
What Discriminates Best Flares in Rheumatoid Arthritis (RA)? a Subanalysis of the Strass Treatment Tapering in RA Study
Agnès Danré¹, Bruno Fautrel², Toni Alfaiate³, Thao Pham⁴, Jacques Morel⁵, Emmanuelle Dernis Labous⁶, Philippe Gaudin⁷, Olivier Brocq⁸, Elisabeth Solau-Gervais⁹, Jean-Marie Berthelot¹⁰, Jean Charles Balblanc¹¹, Xavier Mariette¹², Florence Tubach¹³ and Laure Gossec¹⁴, ¹Rheumatology, La Pitié Salpêtrière, Paris, France, ²Rheumatology, Pitie Salpetriere Hospital, Paris, France, ³department of epidemiology, biostatistics and clinical research, APHP, Hospital Bichat, Paris, France, ⁴Rheumatology, Sainte Marguerite Hospital, Marseille, France, ⁵Department of Rheumatology, Hôpital Lapeyronie, Montpellier, France, ⁶Rhumatologie, Ch Du Mans, Le Mans, France, ⁷Rhumatologie, Hopital Sud Grenoble, Echirolles, France, ⁸Rheumatology, Hospital of Princesse Grâce de Monaco, Monaco, France, ⁹Rheumatology, University Hospital of Poitiers, Poitiers, France, ¹⁰Rheumatology, CHU Nantes (Nantes University Hospital), Nantes, France, ¹¹Rhumatologie, Ch de Belfort, Belfort Cedex, France, ¹²Rheumatology, University Hospital, Le Kremlin Bicetre, Paris, France, ¹³INSERM, Universite Paris Diderot, Paris, France, ¹⁴Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France
Background/Purpose Flares in rheumatoid arthritis (RA) are a patient-perceived increase of disease activity which might be particularly important to assess in the context of treatment…
Abstract Number: 1384 • 2014 ACR/ARHP Annual Meeting
Fibromyalgia and Its Effect on Treatment Response in Early Rheumatoid Arthritis Patients
Josefina Durán Santa Cruz¹, Bernard Combe², Jingbo Niu¹, Nathalie Rincheval³, Cécile Gaujoux-Viala⁴ and David T. Felson⁵, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Immuno-Rhumatologie, Hôpital Lapeyronie, Montpellier, France, ³Institut Universitaire de Recherche Clinique, Montpellier, France, ⁴EA 2415, Montpellier I University, Nîmes University Hospital, Rheumatology Department, Nîmes, France, ⁵Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Fibromyalgia (FM) occurs commonly in patients with rheumatoid arthritis (RA) and its effect on treatment response is unknown. In this study we aimed to…
Abstract Number: 1382 • 2014 ACR/ARHP Annual Meeting
The Longitudinal Course of Fatigue in Rheumatoid Arthritis – Results from the Norfolk Arthritis Register
Katie L Druce¹, Gareth T Jones², Gary J. Macfarlane¹, Suzanne M. Verstappen³ and Neil Basu¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Musculoskeletal Research Collaboration (Epidemiology Group),, University of Aberdeen, Aberdeen, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Fatigue is common and burdensome in Rheumatoid Arthritis (RA). Though RA fatigue progression varies significantly between individuals, to date, published analyses have only considered…
Abstract Number: 1401 • 2014 ACR/ARHP Annual Meeting
Higher-Order Neuropsychological Deficits Are Frequent and Occur Early in RA and SLE: The Impact of Basic Processing Abilities on Psychological Well-Being
Giorgia Dimitraki¹, Georgia Ktistaki¹, Emmanouil Papastefanakis¹, Antonis Fanouriakis², Irini Gergiannaki², George Bertsias³, Nikolaos Kougkas², Argyro Repa³, Evangelos Karademas¹, Prodromos Sidiropoulos³ and Panagiotis Simos¹, ¹Department of Psychology, University of Crete, Rethymnon, Greece, ²Rheumatology, Clinical Immunology and Allergy, University of Crete, Heraklion, Greece, ³Rheumatology, Clinical Immunology, and Allergy, University of Crete, Heraklion, Greece
Background/Purpose Deficits in higher-order cognitive abilities (episodic memory, executive functions) have been reported in patients with chronic inflammatory disorders, albeit inconsistently. We investigated whether such…
Abstract Number: 1400 • 2014 ACR/ARHP Annual Meeting
Risk of Venous Thromboembolic Events in Patients with Rheumatoid Arthritis: A Meta-Analysis of Observational Studies
Michelle Avina¹, Sally Choi², Sharan Rai³, Hyon K. Choi⁴ and Mary De Vera^3,5, ¹Faculty of Sciences, Arthritis Research Centre of Canada/University of British Columbia, Richmond, BC, Canada, ²Arthritis Research Centre of Canada/University of British Columbia, Richmond, BC, Canada, ³Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁴Boston University School of Medicine, Boston, MA, ⁵Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Venous thromboembolism (VTE), which includes both deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common vascular event after myocardial infarction…
Abstract Number: 1399 • 2014 ACR/ARHP Annual Meeting
Proteinase K-like Serine Protease PCSK9 Influence on the Dyslipidemia and Endothelial Dysfunction Observed in Rheumatoid Arthritis Patients
Esmeralda Delgado-Frias¹, Ivan Ferraz-Amaro², Vanesa Hernandez-Hernandez³, A.M. de Vera-Gonzalez⁴, A.F. Gonzalez-Rivero⁵, Miguel A. González-Gay⁶ and Federico Diaz-Gonzalez⁷, ¹Rheumatology, Servicio de Reumatología.Hospital Universitario de Canarias, La Laguna. Tenerife., Spain, ²Rheumatology, Servicio de Reumatologia. Hospital Universitario de Canarias, Tenerife, Spain, ³Rheumatology, Servicio de Reumatologia.Hospital Universitario de Canarias., La Laguna. Tenerife, Spain, ⁴Laboratorio Central, Servicio de Laboratorio Central.Hospital Universitario de Canarias., La Laguna. Spain, Spain, ⁵Laboratorio Central, Servicio de Laboratorio Central. Hospital Universitario de Canarias., La Laguna. Tenerife., Spain, ⁶Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ⁷Rheumatology, Servicio de Reumatologia.Hospital Universitario de Canarias, La Laguna, Spain
Background/Purpose Proteinase K-like serine protease PCSK9 binds the low-density lipoprotein (LDL) receptor at the surface of hepatocytes, thereby preventing its recycling and enhancing its degradation…
Abstract Number: 1383 • 2014 ACR/ARHP Annual Meeting
Disease Characteristics and RA Development in Undifferentiated Arthritis: A 2-Year Follow-up Study of 413 Patients with Arthritis of Less Than 16 Weeks Duration
Gina Hetland Brinkmann^1,2, Ellen Sauar Norli^1,3, Tore K. Kvien¹, Anne Julsrud Haugen², Lars Grøvle², Halvor Nygaard⁴, Cathrine Thunem⁵, Maria Dahl Mjaavatten¹ and Elisabeth Lie¹, ¹Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Dept. of Rheumatology, Østfold Hospital Trust, Fredrikstad, Norway, ³Dept. of Rheumatology, Martina Hansens Hospital, Bærum, Norway, ⁴Dept. of Rheumatology, Lillehammer Hospital of Rheumatic Diseases, Lillehammer, Norway, ⁵Dept. of Medicine, Telemark Hospital, Skien, Norway
Background/Purpose: Correct identification of the subset of patients with undifferentiated arthritis (UA) who will develop rheumatoid arthritis (RA) is important to enable initiation of appropriate…
Abstract Number: 1380 • 2014 ACR/ARHP Annual Meeting
Patient Global Impression of Change for Patient Reported Outcomes in Rheumatoid Arthritis: Impact of Comorbidities
Pankaj Bansal¹, Aneet Kaur², Horace Spencer² and Nasim A. Khan³, ¹Rheumatology/ Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, ²University of Arkansas for Medical Sciences, Little Rock, AR, ³Rheumatology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR
Background/Purpose: Understanding patient’s perspective of minimally clinically important difference (MCID) in health (or disease) status is important to improve patient-centered clinical care and planning and…
Abstract Number: 1379 • 2014 ACR/ARHP Annual Meeting
Studies on Ageing and the Severity of Radiographic Joint Damage in Rheumatoid Arthritis
L. Mangnus¹, H.W. van Steenbergen¹, E. Brouwer², E. Lindqvist³, M. Reijnierse⁴, P.K. Gregersen⁵, S. M. Rantapää-Dahlqvist⁶, D. M. van der Heijde¹ and A. H. M. van der Helm- van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Dept. of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ³Rheumatology, Lund University, Lund, Sweden, ⁴Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁵The Feinstein Institute for Medical Research, Manhasset, NY, ⁶Department for Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden
Background/Purpose: The Western population is getting older; consequently the proportion of elderly persons presenting with Rheumatoid Arthritis (RA) is increasing. We studied whether age is…

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