Abstracts Archive - Page 1927 of 2607 - ACR Meeting Abstracts

Abstract Number: 838 • 2015 ACR/ARHP Annual Meeting
Impaired Quality of Life in Systemic Sclerosis and Patient Perception of the Disease: A Large International Survey
Camelia Frantz¹, Jerome Avouac¹, Oliver Distler², Fazia Amrouche¹, Dominique Godard³, Ann Kennedy⁴, John Varga⁵, Marco Matucci-Cerinic⁶ and Yannick Allanore⁷, ¹Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, ²Division of Rheumatology, University Hospital And Eular Scleroderma Trials And Research (EUSTAR) Board, Zurich, Switzerland, ³Association des Sclérodermie de France, Auxerre, France, ⁴Federation of European Scleroderma Associations (FESCA), Tournai, Belgium, ⁵Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, ⁶Rheumatology Department, University of Florence And World Scleroderma Foundation, Florence, Italy, ⁷Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France
Background/Purpose: Systemic sclerosis (SSc) is recognized as one of the most fatal rheumatic diseases, but it also promotes many detrimental effects on health-related quality of…
Abstract Number: 839 • 2015 ACR/ARHP Annual Meeting
Occupational Exposures in Patients with Systemic Sclerosis Associated with Increased Frequency of Interstitial Lung Disease and Primary Pulmonary Hypertension
Brandi E. Stevens^1,2, Mary Lucas³, Thomas A. Medsger Jr.⁴ and Robyn T. Domsic⁵, ¹Division of Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Medicine-Rheumatology, University of Pittsburgh, Pittsburgh, PA, ³Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴Department of Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁵Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Systemic sclerosis (SSc) has been linked with environmental and occupational exposures. Silica and solvent exposure have the strongest known correlation with SSc. Other agents,…
Abstract Number: 840 • 2015 ACR/ARHP Annual Meeting
Skin Telangiectasia Identify a Subset of Systemic Sclerosis Patients with Severe Vascular Phenotype
Jerome Avouac¹, Charlotte Hurabielle², Gemma Lepri³, Tullia De Risi⁴, Andre Kahan⁵ and Yannick Allanore⁶, ¹Rheumatology A department and INSERM U1016, Paris Descartes University, Cochin Hospital, Paris, France, ²Rheumatology A department, paris Descartes University, Cochin Hospital, Paris, France, ³Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Italy, Florence, Italy, ⁴Rheumatology A department, Paris Descartes University, Cochin Hospital, Paris, France, ⁵Rheumatology A, Cochin Hospital, Paris Cedex 14, France, ⁶Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France
Background/Purpose: Cutaneous Telangiectasia (CT) are common in systemic sclerosis (SSc) patients but their input to risk stratify the patients is poorly known. The aims of…
Abstract Number: 841 • 2015 ACR/ARHP Annual Meeting
Prevalence of Systemic Sclerosis in Primary Biliary Cirrhosis Using the New ACR/EULAR Classification Criteria
Boyang Zheng¹, Catherine Vincent², Marvin J. Fritzler³, Jean-Luc Senécal⁴, Martial Koenig⁵ and France Joyal⁵, ¹Division of Internal Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, ²Division of Hepatology, Centre hospitalier de l'Université de Montréal, Montreal, QC, Canada, ³Medicine, University of Calgary, Calgary, AB, Canada, ⁴Department of Medicine, Division of Rheumatology, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ⁵Department of Medicine, Division of Internal Medicine, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada
Background/Purpose: Systemic sclerosis (SSc) is a well established disease associated with primary biliary cirrhosis (PBC), however original 1980 American College of Rheumatology (ACR) criteria have…
Abstract Number: 842 • 2015 ACR/ARHP Annual Meeting
Clinical Utility of Serial KL-6 Measurement in Interstitial Lung Disease Associated with Systemic Sclerosis
Yuichiro Shirai¹, Tsutomu Takeuchi² and Masataka Kuwana³, ¹Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, ²Keio University School of Medicine, Tokyo, Japan, ³Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan
Background/Purpose: Interstitial lung disease (ILD) is the leading cause of mortality in patients with systemic sclerosis (SSc). KL-6, a mucin-like glycoprotein highly expressed on type…
Abstract Number: 843 • 2015 ACR/ARHP Annual Meeting
Natriuretic Peptide Predicts Mortality in Systemic Sclerosis
Christophe Meune¹, Andras Komocsi², Serena Vettori³, Eric Hachulla⁴, Jerome Avouac⁵, Nicolas Hunzelmann⁶, Jorg HW. Distler⁷ and Yannick Allanore⁸, ¹Cardiology department, Université Paris XIII, Hôpitaux Universitaires Paris-Seine-Saint-Denis, Bobigny, France, ²Heart Institute, University of PECS, Pecs, Hungary, ³Department of Clinical and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, ⁴CHU Lille, Lille, France, ⁵Rheumatology A department and INSERM U1016, Paris Descartes University, Cochin Hospital, Paris, France, ⁶Department of Dermatology, University of Cologne, Cologne, Germany, ⁷Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁸Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France
Background/Purpose: Heart involvement both of primary origin or secondary to lung disease is a key contributor to morbidity and mortality in systemic sclerosis (SSc). While…
Abstract Number: 844 • 2015 ACR/ARHP Annual Meeting
Identification of Subclinical Skin Involvement By High Frequency Ultrasound in Systemic Sclerosis Patients
Barbara Ruaro, Alberto Sulli, Elena Bernero, Marco A. Cimmino, Sabrina Paolino and Maurizio Cutolo, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genoa, Italy
Background/Purpose: Skin involvement may be evaluated in systemic sclerosis (SSc) by modified Rodnan skin score (mRSS), the validated method to distinguish between patients with limited…
Abstract Number: 845 • 2015 ACR/ARHP Annual Meeting
Modelling of Longitudinal Changes in Lung Function in Patients with Systemic Sclerosis and Their Association with Development of Pulmonary Hypertension
Svetlana I. Nihtyanova¹, Voon H. Ong¹ and Christopher P. Denton², ¹Rheumatology, UCL Division of Medicine, London, United Kingdom, ²Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom
Background/Purpose: The majority of published models for prediction of PH use cross-sectional data, while studies exploring the use of repeated measurements of lung function tests…
Abstract Number: 846 • 2015 ACR/ARHP Annual Meeting
Nationwide Trends in in-Hospital Mortality and Hospitalization Associated with Systemic Sclerosis (SSc)
Sara R. Schoenfeld¹, Na Lu¹, Flavia V. Castelino², Marcy B. Bolster² and Hyon K. Choi¹, ¹Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Patients with systemic sclerosis (SSc) experience high rates of morbidity and mortality, but few studies have evaluated health care utilization such as hospitalization rates…
Abstract Number: 847 • 2015 ACR/ARHP Annual Meeting
Troponin T and NT-Probnp Are Prognostic Cardiac Disease Biomarkers in Patients with Systemic Sclerosis without Pulmonary Arterial Hypertension
Silvia Laura Bosello¹, Giacomo De Luca¹, Franca Forni², Clara Di Mario³, Federico parisi¹, Giovanni Canestrari¹, Giorgia Berardi¹, Manuela Rucco¹, Francesca Gabrielli⁴, Leonarda Galiuto⁴, Francesco Loperfido⁴ and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Department of Laboratory Medicine, Catholic University of the Sacred Heart, Rome, Italy, ³Division of Rheumatology, Institute of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ⁴Division of Heart Failure and Cardiac Rehabilitation, Catholic University - Rome, Rome, Italy
Background/Purpose: Heart involvement is common in Systemic Sclerosis (SSc), even if often clinically silent, and represents one of the leading cause of death in these…
Abstract Number: 848 • 2015 ACR/ARHP Annual Meeting
Nitroglycerin Patch Application in Systemic Sclerosis: Evaluation By Laser Doppler Imaging
Georgiana Bentea, Aurelien Wauters, Jean-Claude Wautrecht and Elie Cogan, Erasme Hospital, Brussels, Belgium
Background/Purpose: Systemic sclerosis (SSc) is a complex autoimmune disease, commonly associated with Raynaud phenomenon (RP). The aim of this study was to characterize the microvascular…
Abstract Number: 849 • 2015 ACR/ARHP Annual Meeting
A Computational Tool for Individualized Prognosis of Percent of Predicted Forced Vital Capacity Trajectories in Systemic Sclerosis
Peter Schulam¹, Colin Ligon², Robert Wise³, Laura K. Hummers⁴, Fredrick M. Wigley⁵ and Suchi Saria^1,6, ¹Department of Computer Science, Johns Hopkins University, Baltimore, MD, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Department of Pulmonology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Rheum Div/Mason F Lord, Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Departments of Biostatistics, and Health Policy and Management, Bloomberg School of Public Health, Baltimore, MD
Background/Purpose: Interstitial lung disease (ILD) is a common cause of mortality in systemic sclerosis (Ssc). Decreased forced vital capacity (FVC) in Ssc-ILD is associated with…
Abstract Number: 850 • 2015 ACR/ARHP Annual Meeting
Incidence and Predictors of Severe Heart Disease in Systemic Sclerosis
Serena Vettori¹, Yannick Allanore², Laszlo Czirjak³, Francesco Del Galdo⁴, Christopher P. Denton⁵, Oliver Distler⁶, Ivan Foeldvari⁷, Marc Frerix⁸, Veronika K. Jaeger⁹, Brigitte Krummel-Lorenz¹⁰, Marco Matucci Cerinic¹¹, Carina Mihai¹², Ulf Müller-Ladner¹³, Gabriela Riemekasten¹⁴, Tim Schmeiser¹⁵, Ingo H. Tarner⁸, Ulrich A. Walker⁹, Gabriele Valentini¹⁶ and EUSTAR Group and DeSScipher Consortium, ¹Department of Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, ²Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France, ³Rheumatology and Immunology Medical School, University of Pécs, Pécs, Hungary, ⁴Division of Musculoskeletal Diseases, University of Leeds, Leeds, United Kingdom, ⁵Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, ⁶Department of Rheumatology and Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁷Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ⁸Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, ⁹Department of Rheumatology, University Hospital Basel, Basel, Switzerland, ¹⁰Rheumatologist, Frankfurt, Germany, ¹¹Department of Internal Medicine, Division of Rheumatology, University of Florence, Florence, Italy, ¹²Internal Medicine and Rheumatology Departement, Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Bucharest, Romania, ¹³Internal Medicine and Rheumatology, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, ¹⁴Rheumatology and Clinical Immunology, Charité – University Hospital, Berlin, Berlin, Germany, ¹⁵Internistic Rheumatology, Krankenhaus St. Josef, Wuppertal, Germany, ¹⁶Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy
Background/Purpose: Heart disease occurs in most patients with systemic sclerosis (SSc), as emerged by autopsy and imaging studies. It can cause cardiac blocks (CBs), ventricular…
Abstract Number: 851 • 2015 ACR/ARHP Annual Meeting
Does the Clinical Context Improve the Reliability of Rheumatologists Grading Digital Ulcers in Systemic Sclerosis?
Michael Hughes¹, Chris Roberts², Andrew Tracey¹, Graham Dinsdale¹, Andrea Murray¹ and Ariane L. Herrick¹, ¹Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, ²Centre for Biostatistics, Institute of Population Health, University of Manchester, Manchester, United Kingdom
Background/Purpose: Digital ulcers (DUs) are often a primary end point in SSc clinical trials, although the reliability of rheumatologists grading DUs is poor to moderate…
Abstract Number: 852 • 2015 ACR/ARHP Annual Meeting
Health-Related Quality of Life in Early Systemic Sclerosis
Marie Hudson¹, Murray Baron², Mianbo Wang³, Candice Rabusa⁴, Susanna Proudman⁵, Mandana Nikpour⁶, Wendy Stevens⁴ and Canadian Scleroderma Research Group (CSRG), Australian Scleroderma Cohort Study (ASCS), ¹McGill University, Jewish General Hospital, Montreal, QC, Canada, ²Jewish General Hospital, Lady Davis Institute and McGill University, Montreal, QC, Canada, ³Lady Davis Institute for Medical Research, Montreal, QC, Canada, ⁴Rheumatology, St. Vincent’s Hospital, Melbourne, Australia, ⁵Rheumatology Unit, Royal Adelaide Hospital North Terrace, Adelaide, Australia, ⁶University of Melbourne Department of Medicine, Melbourne, Australia
Background/Purpose: Health-related quality of life (HRQoL) research is a priority in systemic sclerosis (SSc). Yet, much of the data comes from prevalent cohorts with established…

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