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  • Abstract Number: 446 • 2015 ACR/ARHP Annual Meeting

    Low Disease Activity at 12 Weeks and 24 Weeks Is Predictive of Normalized Health-Related Quality of Life in Methotrexate-Experienced Patients with Active Rheumatoid Arthritis Treated with Intravenous Golimumab Plus Methotrexate

    Clifton O. Bingham III1, Michael Weinblatt2, Rene Westhovens3, Lilianne Kim4, Chenglong Han5, Stephen Xu4, Kim Hung Lo4, Kezhen L. Tang4, Elizabeth C. Hsia4,6, Dennis Parenti7 and Shelly Kafka7, 1Rheumatology, Johns Hopkins University, Baltimore, MD, 2Brigham and Women's Hospital, Boston, MA, 3UZ Gasthuisberg, Leuven, Belgium, 4Janssen Research & Development, LLC, Spring House, PA, 5Janssen Global Services, LLC, Malvern, PA, 6University of Pennsylvania, Philadelphia, PA, 7Janssen Scientific Affairs, LLC, Horsham, PA

    Background/Purpose: Previous analyses in patients (pts) with rheumatoid arthritis (RA) have evaluated the relationship between controlling disease activity and achieving long-term improvements in health-related quality…
  • Abstract Number: 447 • 2015 ACR/ARHP Annual Meeting

    Components of Treatment Delay in Rheumatoid Arthritis Differ According to Autoantibody Status

    Arthur G Pratt1, Ben Hargreaves2, Dennis W Lendrem2, Osman Aslam2 and John D Isaacs2, 1Institute of Cellular Medicine (Musculoskeletal Research Group), National Institute for Health Research Newcastle Biomedical Research Centre based at Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, 2Institute of Cellular Medicine (Musculoskeletal Research Group), NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom

    Background/Purpose: Despite a proliferation of early arthritis (EA) clinics intended to expedite the diagnosis of rheumatoid arthritis (RA), patients continue to experience substantial and multifactorial…
  • Abstract Number: 448 • 2015 ACR/ARHP Annual Meeting

    A Majority of Early Rheumatoid Arthritis (ERA) Patients Reach Remission By 6 Months in Usual Rheumatology Care

    Tuomas Rannio1, Juha Asikainen2, Pekka Hannonen3, Timo Yli-Kerttula4, Päivi Ekman5, Laura Pirilä6, Markku Mali7, Laura Kuusela7, Maija Puurtinen-Vilkki7, Saara Kortelainen8, Johanna Paltta7, Kirsi Taimen7, Heidi Mäkinen9, Pia Isomäki9, Terhi Uotila9, Markku J. Kauppi10, Kari Laiho11, Satu Nyrhinen11, Tuulikki Sokka-Isler1 and FIN-ERA study group, 1Rheumatology, Jyvaskyla Central Hospital, Jyvaskyla, Finland, 2Jyväskylä Central Hospital, Jyväskylä, Finland, 3Jyvaskyla Central Hospital, Jyvaskyla, Finland, 4Sairaalantie 3, Central Hospital of Satakunta, Pori, Finland, 5Central Hospital of Satakunta, Pori, Finland, 6Tyks, P.O. Box 52, Turku University Central Hospital, Turku, Finland, 7Turku University Central Hospital, Turku, Finland, 8Alvar Aallontie 275, Turku University Central Hospital, Turku, Finland, 9Tampere University Hospital, Tampere, Finland, 10Department of Rheumatology, Päijät-Häme Central Hospital, Lahti, Finland, 11Päijät-Häme Central Hospital, Lahti, Finland

    Background/Purpose: Finnish national combination treatment trials have demonstrated excellent outcomes in patients with ERA including 90% of patients reaching DAS28 remission at 6 months. Whether…
  • Abstract Number: 449 • 2015 ACR/ARHP Annual Meeting

    Change from SC to IV Abatacept and Back in Patients with Rheumatoid Arthritis As Simulation of a Vacation: A Prospective Phase IV, Open Label Trial (A-BREAK)

    Ruediger Mueller1, Michael Gengenbacher2, Symi richter3, Jean Dudler4, Burkhard Moeller5 and Johannes von Kempis6, 1Rheumatology, MD, St. Gallen, Switzerland, 2Bethesdaspital, Basel, Switzerland, 3Bethsdaspital, Basel, Switzerland, 4Kantonsspital Fribourg, Fribourg, Switzerland, 5Rheumatology, Inselspital-University Hospital, Bern, Switzerland, 6Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland

    Background/Purpose: Holiday seasons can present a major problem to RA patients treated with weekly subcutaneous biologics, including subcutaneous (SC) abatacept. Therefore an evaluation of the…
  • Abstract Number: 450 • 2015 ACR/ARHP Annual Meeting

    Use of Tofacitinib in a Real World Setting:  Clinical Features in a Cohort of Patients Using the Database Jointman Compared to a Published Clinical Trial

    Sergio Schwartzman1, Keith Knapp2, Gary Craig3, Karen Ferguson4 and Howard Kenney5, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Arthritis Northwest, Spokane, WA, 3Discus Analytics, Inc., Spokane, WA, 4Arthritis Northwest PLLC., Spokane, WA, 5Rheumatology, Arthritis Northwest, Spokane, WA

    Background/Purpose: It is well accepted that patients studied in pharmaceutically sponsored clinical trials do not always represent the types of patients seen in clinical practice. …
  • Abstract Number: 451 • 2015 ACR/ARHP Annual Meeting

    Efficacy of Tofacitinib in a Real World Setting Using the Database Jointman

    Sergio Schwartzman1, Keith Knapp2, Gary Craig3, Karen Ferguson4 and Howard Kenney5, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Arthritis Northwest, Spokane, WA, 3Discus Analytics, Inc., Spokane, WA, 4Arthritis Northwest PLLC., Spokane, WA, 5Rheumatology, Arthritis Northwest, Spokane, WA

    Background/Purpose: Tofacitinib (TFA) was approved for the treatment of rheumatoid arthritis (RA) in November of 2012. It is well accepted that patients studied in pharmaceutically…
  • Abstract Number: 452 • 2015 ACR/ARHP Annual Meeting

    Associations Between Arthritis Patient, Disease-Specific and Provider Characteristics and Medication Information Source Use

    Lorie Geryk1, Susan J. Blalock2, Robert DeVellis3, Joanne M. Jordan3 and Delesha Carpenter4, 1Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, 2Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, 4Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Asheville, NC

    Background/Purpose: Few studies have described how patient, disease-specific, and provider factors are associated with medication information source use among arthritis patients. We address this research…
  • Abstract Number: 453 • 2015 ACR/ARHP Annual Meeting

    Highly Elevated Rheumatoid Factor Is a Risk Factor for Abatacept Treatment Failure in Japanese Patients with Rheumatoid Arthritis

    Shunya Kaneshita1, Chisun Min1, Omata Fumio2, Masei Suda1, Ryo Rokutanda1, Hisanori Shimizu3, Tokutaro Tsuda1, MItsumasa kishimoto4, Ken-ichi Yamaguchi3 and Masato Okada3, 1Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, 2Center for Clinical Epidemiology, St.Luke' International Hospital and St. Luke's Life Science Institute, Tokyo, Japan, 3Allergy and Rheumatology, St. Luke's International Hospital, Tokyo, Japan, 4St. Luke's International Hospital, Tokyo, Japan

    Background/Purpose: It is valuable to predict the effectiveness of biologics in the patients with rheumatoid arthritis (RA) to avoid unnecessary side effects and to save…
  • Abstract Number: 454 • 2015 ACR/ARHP Annual Meeting

    No Sex Bias in the Escalation of Therapy in the Treatment of Early Inflammatory Arthritis

    Stephanie Garner1, Cheryl Barnabe2, Gilles Boire3, Carol Hitchon4, Edward C. Keystone5, Boulos Haraoui6, J Carter Thorne7, Diane Tin8, Janet E. Pope9, VP Bykerk10 and CATCH Investigators, 1University of Calgary, Calgary, AB, Canada, 2Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 3Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, 4Department of Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 5Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 6Institut de Rhumatologie, Montreal, QC, Canada, 7University of Toronto, Toronto, ON, Canada, 8The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, 9University of Western Ontario, London, ON, Canada, 10Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Several studies have shown that females with early inflammatory arthritis have higher disease activity, worse functional impairment and worse patient-reported outcomes but do not…
  • Abstract Number: 455 • 2015 ACR/ARHP Annual Meeting

    Predictors of Real-World Treatment Sustainability in RA Patients Treated with Abatacept in Canada: Implications for Routine Care

    Janet E. Pope1, Emmanouil Rampakakis2 and John S. Sampalis3, 1University of Western Ontario, London, ON, Canada, 2JSS Medical Research, St-Laurent, QC, Canada, 3Clinical Research, JSS Medical Research, Westmount, QC, Canada

    Background/Purpose: Treatment sustainability can measure drug effectiveness and encompasses drug effectiveness, safety, and compliance. Recent data suggest that differences in retention may exist between biologic…
  • Abstract Number: 456 • 2015 ACR/ARHP Annual Meeting

    Disease and Treatment Characteristics That Might Influence Long-Term Retention with Biologics in the Real-World Clinical Setting: Experience from the Rhumadata Clinical Database and Registry 

    Denis Choquette1, Louis Bessette2, Boulos Haraoui3, Jean-Pierre Raynauld1, Diane Sauvageau1, Angèle Turcotte4, Édith Villeneuve1 and Louis Coupal1, 1Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 2Centre d’Ostéoporose et de Rhumatologie de Québec (CORQ), Québec, QC, Canada, 3Institut de Rhumatologie, Montreal, QC, Canada, 4Rheumatology, Centre d’ostéoporose et de rhumatologie de Québec (CORQ), Québec, QC, Canada

    Disease and Treatment Characteristics that Might Influence Long-term Retention with Biologics in the Real-world Clinical Setting: Experience from the Rhumadata Clinical Database and Registry  Background/Purpose:…
  • Abstract Number: 457 • 2015 ACR/ARHP Annual Meeting

    RA Patients with Medicare Only Insurance Have Similar Clinical Outcomes As Patients with Private Insurance Despite Having Less Access to Biologics

    Marcia S. Genta1, Amnon Sonnenberg2 and Robert M. Genta3, 1Dallas Arthritis Center, Dallas, TX, 2Medicine - Gastroenterology, Portland VAMC - Oregon Health & Science University, Portland, OR, 3Laboratory, Dallas Arthritis Center, Dallas, TX

    Background/Purpose: We have previously shown that patients with Medicare only coverage without financial assistance from foundations were significantly less likely to receive Biologics than patients…
  • Abstract Number: 458 • 2015 ACR/ARHP Annual Meeting

    First Year Canadian Experience with Subcutaneous Abatacept in Routine Practice for the Treatment of Patients with Rheumatoid Arthritis: Data from the Orencia Response Program (ORP) Network

    Boulos Haraoui1, Louis Coupal2, Radmila Day3, Lionel Budry4 and Youb Chalabi5, 1Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, 2Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 3None, Montreal, QC, Canada, 4Bristol Myers Squibb Canada, St-Laurent, QC, Canada, 5Bristol Myers Squibb, Montreal, QC, Canada

    Background/Purpose: The subcutaneous (SC) formulation of abatacept (ABA) has been available in Canada since January 2014. Here we report first year experience with SC ABA…
  • Abstract Number: 459 • 2015 ACR/ARHP Annual Meeting

    The Effect of Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Positivity on Drug Survival of Abatacept in Patients with Rheumatoid Arthritis in Routine Care: The Results from Turkbio Registry

    Ihsan Ertenli1, Omer Karadag1, Yavuz Pehlivan2, Ediz Dalkilic3, Ahmet Mesut Onat4, Bunyamin Kisacik5, Gercek Can6, Servet Akar7, Sedat Capar8, Umut Kalyoncu1, Mustafa Ferhat Oksuz9, Emine Figen Tarhan7 and Nurullah Akkoc6, 1Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Department of Rheumatology, Uludag University Faculty of Medicine, Bursa, Turkey, 3Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey, 4Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 5Rheumatology Department, Gaziantep University School of Medicine, Gaziantep, Turkey, 6Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey, 7Department of Internal Medicine, Division of Rheumatology, Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 8Dokuz Eylül University Faculty of Statistics, Izmir, Turkey, 9Rheumatology, Uludag University Faculty of Medicine, Bursa, Turkey

    Background/Purpose: Abatacept (ABA) is a biological anti-rheumatic drug used in Rheumatoid Arthritis (RA). In TURKBIO, Turkish Biologic Registry, data on patient characteristics, diagnosis, previous treatment…
  • Abstract Number: 460 • 2015 ACR/ARHP Annual Meeting

    Changes in Body Composition and Metabolic Profile during Treatment with Tocilizumab in Patients with Rheumatoid Arthritis

    Anne Tournadre1, Bruno Pereira2, Frederic Dutheil3, Vincent Sapin4, Charlotte Giraud5, Sandrine Malochet-Guinamand6, Thomas Frayssac7, Sylvain Mathieu5, Jean-Jacques Dubost8 and Martin Soubrier8, 1Rheumatology, UNH-UMR 1019 INRA University of Auvergne and Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 2Biostatistics unit (DRCI), CHU Clermont-Ferrand, Clermont-Ferrand, France, 3Preventive and Occupational Medicine, CHU G. Montpied Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions EA3533, Clermont-Ferrand, France, 4Biochemistry and Molecular Biology Department CHU Clermont-Ferrand, Clermont Université, Université d'Auvergne, EA7281, Clermont-Ferrand, France, 5Rheumatology, Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 6Rheumatology Department,, Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 7Rheumatology, Rheumatology department CHU Clermont-Ferrand, Clermont-ferrand, France, 8Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by increased cardiovascular risk and metabolic changes including cachectic obesity, insulin resistance, dyslipidemia. DMARDs decrease inflammation and could thus…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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