Abstracts Archive - Page 1901 of 2425 - ACR Meeting Abstracts

Abstract Number: 2289 • 2014 ACR/ARHP Annual Meeting
Accuracy of the Use of Administrative Diagnostic Codes to Identify Pediatric in-Patient Musculoskeletal Conditions in an African Tertiary Hospital
Rosie Scuccimarri¹, Carol Hitchon², Sasha Bernatsky³, Eugene Were⁴, Thomas Ngwiri⁵ and Ines Colmegna⁶, ¹Rheumatology, Montreal Children's Hospital, Montreal, QC, Canada, ²Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ³Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, ⁴Gertrude's Children's Hospital, Nairobi, Kenya, ⁵Pediatrics, Gertrude's Children's Hospital, Nairobi, Kenya, ⁶Rheumatology, McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: The spectrum and frequency of pediatric rheumatic conditions in East Africa are unknown. Administrative data that is systematically collected using International Classification of Disease…
Abstract Number: 2290 • 2014 ACR/ARHP Annual Meeting
Race and Other Risk Markers of Uveitis in a Prospective Cohort of Children with Juvenile Idiopathic Arthritis
Sheila T. Angeles-Han¹, Courtney McCracken¹, Steven Yeh², Kirsten Jenkins³, Erica Myoung⁴, Daneka Stryker⁴, Kelly A. Rouster-Stevens⁵, Larry B. Vogler¹, Christine Kennedy⁶, Sampath Prahalad¹ and Carolyn Drews-Botsch⁷, ¹Emory University School of Medicine, Atlanta, GA, ²Ophthalmology, Emory University School of Medicine, Atlanta, GA, ³Children's Healthcare of Atlanta, Atlanta, GA, ⁴Emory University, Atlanta, GA, ⁵Pediatrics, Emory University School of Medicine, Atlanta, GA, ⁶Rheumatology Immunology, Emory Children's Center, Atlanta, GA, ⁷Epidemiology, Emory University School of Public Health, Atlanta, GA
Background/Purpose Juvenile idiopathic arthritis-associated uveitis (JIA-U) can lead to poor visual outcomes. American Academy of Pediatric guidelines recommend screening every 3 months in children with…
Abstract Number: 2291 • 2014 ACR/ARHP Annual Meeting
Canakinumab in Biologic-naïve Versus Previously Biologic-Exposed Systemic Juvenile Idiopathic Arthritis Patients: Efficacy Results from a 12 Week Pooled Post Hoc Analysis
A Grom¹, P Quartier², N Ruperto³, H.I Brunner¹, K Schikler¹, M Erguven³, L Goffin³, M Hofer³, T Kallinich³, K Marzan¹, C Gaillez⁴, K Lheritier⁴, K Abrams⁵, A Martini³ and D.J Lovell¹, ¹PRCSG, Cincinnati, OH, ²Hôpital Necker-Enfants Malades, Paris, France, ³PRINTO-Istituto Gaslini, Genova, Italy, ⁴Novartis Pharma AG, Basel, Switzerland, ⁵Novartis Pharmaceutical Corporation, East Hanover, NJ
Background/Purpose: Efficacy and safety of canakinumab (CAN), a selective, human, anti-IL-1β monoclonal antibody, was previously demonstrated in 2 phase III trials.1 Out of these trials…
Abstract Number: 2251 • 2014 ACR/ARHP Annual Meeting
Kneeling Disability Associated with the Treatment of Osteoarthritis: Analysis of a Copcord Study in Mexico
Alexia Hernández-Cáceres¹, Jacqueline Rodríguez-Amado¹, Ingris Peláez-Ballestas², David Vega-Morales³, Mario Garza-Elizondo¹, Roberto Negrete-López¹, Lorena Pérez-Barbosa¹ and Janett Riega-Torres¹, ¹Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ²Departamento de Reumatología, Departamento de Reumatología Hospital General de México “Dr. Eduardo Liceaga”, Distrito Federal, Mexico, ³Rheumatology, Hospital Universitario UANL, Monterrey, Mexico
Background/Purpose Osteoarthritis (OA) is the most prevalent rheumatic disease in Mexico. The core treatment, a combination of pharmacological and non-pharmacological modalities, is mainly performed in…
Abstract Number: 2252 • 2014 ACR/ARHP Annual Meeting
Autoimmune Thyroid Disease Is Associated with a Higher Frequency of Spinal Degenerative Disc Disease
Asha Shrestha¹, Hillel Cohen² and Clement Tagoe¹, ¹Rheumatology, Albert Einstein College of Medicine, Bronx, NY, Bronx, NY, ²Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, Bronx, NY
Background/Purpose: Autoimmune thyroid disease (AITD) has been linked to a number of rheumatic syndromes including arthritis and generalized pain. Although AITD has been associated with…
Abstract Number: 2253 • 2014 ACR/ARHP Annual Meeting
Effect of Teriparatide in Patients with Osteoporosis with Prior Vertebral Fracture
Guillermo Valenzuela¹, Douglas Yim², Douglas Beall³, Michael Gordon⁴, John H. Krege⁵ and Kelly D. Krohn⁶, ¹Integral Rheumatology and Immunology Specialists, Plantation, FL, ²Division of Vascular & Interventional Radiology, University of California, Irvine Medical Center, Orange, California, Orange, CA, ³Clinical Radiology of Oklahoma, Edmond, Oklahoma, Edmonda, OK, ⁴Newport Orthopedic Institute, Newport Beach, California, Newport Beach, CA, ⁵Eli Lilly and Company, LLC, Indianapolis, Indiana, Indianapolis, IN, ⁶DC 5208, Eli Lilly and Company, LLC, Indianapolis, Indiana, Indianapolis, IN
Background/Purpose: The Direct Assessment of Nonvertebral Fracture in Community Experience (DANCE) study was an open-label, prospective, observational study that examined occurrence of nonvertebral fragility fractures…
Abstract Number: 2254 • 2014 ACR/ARHP Annual Meeting
Changes in Subject Characteristics in the Denosumab Pivotal Fracture Trial and Its Extension for up to 8 Years
JD Adachi¹, CJF Lin², PR Ho², MA Bolognese³, HG Bone⁴, P Hadji⁵, S Papapoulos⁶, C Recknor⁷, NS Daizadeh², P Dakin², RB Wagman² and S Ferrari⁸, ¹McMaster University, Hamilton, ON, Canada, ²Amgen Inc., Thousand Oaks, CA, ³Bethesda Health Research Center, Bethesda, MD, ⁴Michigan Bone and Mineral Clinic, Detroit, MI, ⁵Philipps-University of Marburg, Marburg, Germany, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷United Osteoporosis Centers, Gainesville, GA, ⁸Geneva University Hospital, Geneva, Switzerland
Background/Purpose: Changes in demographics of study population enrolled in long-term osteoporosis clinical trials may affect interpretation of efficacy/safety outcomes. Denosumab is being evaluated for up…
Abstract Number: 2255 • 2014 ACR/ARHP Annual Meeting
Vertebral Cortical Bone Mass and Structure Significantly Improved with Romosozumab Compared with Teriparatide: HR-QCT Analyses of Postmenopausal Women with Low BMD from a Phase 2 Study
T Damm¹, C Libanati², J Peña¹, G Campbell¹, R Barkmann¹, DA Hanley³, S Goemaere⁴, MA Bolognese⁵, C Recknor⁶, C Mautalen⁷, YC Yang² and CC Glüer¹, ¹Christian-Albrechts-Universität zu Kiel, Kiel, Germany, ²Amgen Inc., Thousand Oaks, CA, ³University of Calgary, Calgary, AB, Canada, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Bethesda Health Research Center, Bethesda, MD, ⁶United Osteoporosis Centers, Gainesville, GA, ⁷Centro de Osteopatias Medicas, Buenos Aires, Argentina
Background/Purpose : Understanding the effect of therapies in the vertebral compartments is relevant to bone biology and clinical practice. We developed an improved technique using…
Abstract Number: 2256 • 2014 ACR/ARHP Annual Meeting
Effects of Pre-Dosage Alendronate Treatment on Bone Metabolic Indices and Bone Mineral Density in Patients Treated with Glucocorticoids: A Prospective Study
Yasuo Kuroki¹, Hiroshi Kaji², Mika Yamauchi³ and Toshitsugu Sugimoto⁴, ¹Dept of Internal Medicine, Kobe Century Memorial Hospital, Kobe, Japan, ²Department of Physiology and Regenerative Medicine, Kinki University Faculty of Medicine, Osakasayama, Japan, ³Internal Medicine 1, Shimane University Faculty of Medicine, Izmo, Japan, ⁴Internal Medicine 1, Shimane University Faculty of Medicine, Izumo, Japan
Background/Purpose: Glucocorticoids (GCs) treatment induces secondary osteoporosis characterized by rapid bone loss and an increase in fracture risk, although GCs are used to treat a…
Abstract Number: 2257 • 2014 ACR/ARHP Annual Meeting
How Does Non-Compliance to Prolia ® (DENOSUMAB) Impact the Change in Bone Mineral Density (BMD) in Osteoporotic Patients?
Aashish Kalani¹, Matt Wong-Pack¹, Jacob Hordyk², Arthur N. Lau³, George Ioannidis⁴, Robert Bensen⁵, William G. Bensen⁶ and Jonathan D. Adachi¹, ¹McMaster University, Hamilton, ON, Canada, ²University of Ottawa, Hamilton, ON, Canada, ³Rheumatology and Clinical Epidemiology, Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ⁴St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ⁵Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ⁶Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada
Background/Purpose: Denosumab (Prolia®) has shown to be a safe and efficacious therapy for osteoporotic patients in many clinical trials. Unfortunately, few studies have explored its effectiveness…
Abstract Number: 2259 • 2014 ACR/ARHP Annual Meeting
Changes in serum Soluble RANKL and Osteoprotegerin Levels after Teriparatide Administration in Rheumatic Disease Patients with Glucocorticoid-Induced Osteoporosis
Makoto Kaburaki, Kaichi Kaneko, Kotaro Shikano, Mai Kawazoe, Emiko Shindo, Hiroshi Sato, Natsuki Fujio, Sei Muraoka, Nahoko Tanaka, Tatsuhiro Yamamoto, Natsuko Kusunoki, Tomoko Hasunuma, Shinichi Kawai and Shotaro Masuoka, Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan
Background/Purpose ,Osteoporosis is one of the serious complications of systemic glucocorticoid therapy. Reduced bone formation is the key process in patients with glucocorticoid-induced osteoporosis (GIOP),…
Abstract Number: 2260 • 2014 ACR/ARHP Annual Meeting
Effects of Daily Teriparatide on the Spine and Femoral Strength Assessed By Finite Element Analysis of Clinical Computed Tomography in Rheumatoid Arthritis Patients
Kumiko Ono¹, Satoru Ohashi², Hiroyuki Oka³, Yuho Kadono⁴, Tetsuro Yasui⁴, Yasunori Omata⁴, Naoko Shoda⁴ and Sakae Tanaka¹, ¹Orthopaedic Surgery and Spinal Surgery, The University of Tokyo Hospital, Tokyo, Japan, ²Department of Orthopaedic Surgery, Sagamihara Hospital,National Hospital Organization, Kanagawa, Japan, ³Department of Joint Disease Research, 22nd Century Medical & Research Center, faculty of medicine,the university of Tokyo, Tokyo, Japan, ⁴Department of Orthopaedic Surgery and Spine Surgery, The University of Tokyo Hospital, Tokyo, Japan
Background/Purpose Rheumatoid arthritis (RA) decreases bone mineral density and bone quality, and exposes patients to an increased risk of fracture. In RA treatment, improvement of…
Abstract Number: 2261 • 2014 ACR/ARHP Annual Meeting
A Meta-Anlaysis of Bisphosphonate and Parathyroid Hormone (PTH) Use in Osteoporosis
Zsolt Kulcsar¹, Lena Saleh², Shravani Gangidi³ and Poonam Khadka⁴, ¹Rheumatology/Leadership Preventive Medicine Residency, Dartmouth Hitchcock Medical Center, lebanon, NH, ²The Dartmouth Institute For Healthcare Policy and Clinical Practice, Lebanon, NH, ³The Dartmouth Institute For Healthcare Policy and Clinical Practice, lebanon, NH, ⁴Endocrinology, Dartmouth Hitchcock Medical Center, lebanon, NH
Background/Purpose: Bisphosphonates are currently the drug of choice for treatment of osteoporosis. While anabolic agents like parathyroid hormone (PTH) have shown greater improvements in bone…
Abstract Number: 2262 • 2014 ACR/ARHP Annual Meeting
Raloxifene for Osteoporosis in Postmenopausal Women with Rheumatic Diseases
Won Seok Lee¹, Yun Jung Choi², Yun-Hong Cheon¹, Myong-Joo Hong³, Chang-Hoon Lee⁴, Myeung Su Lee⁴, Sang-Il Lee⁵ and Wan-Hee Yoo⁶, ¹Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ²Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, JeonJu, South Korea, ³Department of internal Medicine, Presbyterian Medical center, Jeonju, South Korea, ⁴Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ⁶Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea
Background/Purpose : Raloxifen is a selective estrogen receptor modulator that has been extensively studied. We studied the efficacy of raloxifene on disease activity and bone…
Abstract Number: 2263 • 2014 ACR/ARHP Annual Meeting
Continued Zoledronic Acid Use in a Large Healthcare System
Robert A. Overman¹, Julie C. Lauffenburger², Margaret L. Gourlay³ and Chad L. Deal⁴, ¹Eshelman School of Pharmacy - Division of Pharmaceutical Policy and Outcomes, University of North Carolina, Chapel Hill, NC, ²Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, ³Family Medicine, University of North Carolina, Chapel Hill, NC, ⁴Dept of Rheum & Imm Dis /A 50, Cleveland Clinic, Cleveland, OH
Background/Purpose: Oral bisphosphonates adherence has been reported as less than 50% at one year. With patients frequently having refill gaps greater than 30 days. Zoledronic…

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