Abstracts Archive - Page 1897 of 2425 - ACR Meeting Abstracts

Abstract Number: 2350 • 2014 ACR/ARHP Annual Meeting
A Humanized Monoclonal Antibody Raised Against a Heat Shock Protein Epitope Suppresses Autoimmune Inflammatory Diseases By Skewing the Immune System Selectively Towards an Anti-Inflammatory Response
Yaakov Naparstek¹, Rina Ulmansky², Galia Katzavian³, Ronit Meyuhas³, Eli Moallem⁴, Shira Yair³, Dorit Landstein³ and Virginie Loeb³, ¹Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel, ²Hadassah - Hebrew University Medical Center, Jerusalem, Israel, ³ProtAb Ltd., Jerusalem, Israel, ⁴Dept. of Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
Background/Purpose We have previously shown that resistance to Adjuvant Arthritis (AA) is due to the presence of anti-heat shock protein (HSP) antibodies, directed at peptide-6,…
Abstract Number: 2351 • 2014 ACR/ARHP Annual Meeting
Ligand of Glucocorticoid-Induced Tumor Necrosis Factor Receptor Enhances Th17 Cells Response in Collagen-Induced Arthritis Via P38 MAPK and STAT3 Pathway
Xinyi Tang¹ and Shengjun Wang², ¹Department of Laboratory Medicine, Jiangsu University Affi�liated People’s Hospital, Zhenjiang, China, ²Department of Laboratory Medicine, Jiangsu University Affiliated People’s Hospital, Zhenjiang, China
Background/Purpose Helper T lymphocyte-17 (Th17) has recognized to be an important factor in rheumatoid arthritis (RA) pathogenesis. The natural ligand of glucocorticoid-induced tumor necrosis factor…
Abstract Number: 2352 • 2014 ACR/ARHP Annual Meeting
RORγt Expressing Foxp3⁺ Regulatory T Cells Regulates the Development of Autoimmune Arthritis in Mice
Yuya Kondo¹, Masahiro Tahara¹, Mana Iizuka¹, Masahiro Yokosawa¹, Shunta Kaneko¹, Hiroto Tsuboi¹, Satoru Takahashi², Isao Matsumoto³ and Takayuki Sumida¹, ¹Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan, ³Department of Interenal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Background/Purpose: To determine the effect of RORγt overexpression in T cells on the development of collagen induced arthritis (CIA). Methods: Arthritis was induced with chicken…
Abstract Number: 2312 • 2014 ACR/ARHP Annual Meeting
Use of Physician Extenders to Improve Quality and Efficiency of Clinical Visits
Carl Orr¹, Francis Young¹, Lorraine O' Neill¹, Mairead Murray¹, Phil Gallagher² and Douglas J. Veale³, ¹Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ²Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ³Translational Rheumatology Research Group, St. Vincent's University Hospital, Dublin 4, Ireland
Background/Purpose Logistical difficulties associated with managing a large, publically funded secondary service, means that service delivery is costly in terms of physician time. Patients frequently…
Abstract Number: 2313 • 2014 ACR/ARHP Annual Meeting
Best Practices for Best Practice Alerts: Evaluation of a Best Practice Alert to Detect Chronic Glucocorticoid Use
Mingyuan Zhang¹, Catherine Staes¹, Lara Kapp² and Karla L. Miller³, ¹Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, ²University of Utah School of Medicine, Salt Lake City, UT, ³Internal Medicine-Division of Rheumatology, University of Utah School of Medicine, SLC, UT
Background/Purpose Chronic glucocorticoid (GC) use is a known risk factor for osteoporosis and fracture. Patients with chronic GC use often receive suboptimal osteoporosis prevention, diagnosis,…
Abstract Number: 2314 • 2014 ACR/ARHP Annual Meeting
Dexa Testing in Long-Term Steroid Use
Beth Scholz, Internal medicine, University of Texas Health Science Center at Houston, Houston, TX
Background/Purpose: Risk stratification in the ACR glucocorticoid-induced osteoporosis guidelines includes DEXA testing, which is not universally implemented at our rheumatology clinic. DEXA utilization should be…
Abstract Number: 2315 • 2014 ACR/ARHP Annual Meeting
Glucocorticoid Induced Osteoporosis Screening and Treatment in a Cohort of Male Patients with Underlying Rheumatologic Diagnosis in a Tertiary Care Setting
Hajra Shah, Narender Annapureddy, Joel A. Block and Ruchi Jain, Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: One-fourth of hip fractures occur in men. Three groups of men are at high risk for fracture: those who have already suffered a fragility…
Abstract Number: 2316 • 2014 ACR/ARHP Annual Meeting
Adherence to Denosumab in a Large Healthcare System
Robert A. Overman¹, Julie C. Lauffenburger², Margaret L. Gourlay³ and Chad L. Deal⁴, ¹Eshelman School of Pharmacy - Division of Pharmaceutical Policy and Outcomes, University of North Carolina, Chapel Hill, NC, ²Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, ³Family Medicine, University of North Carolina, Chapel Hill, NC, ⁴Dept of Rheum & Imm Dis /A 50, Cleveland Clinic, Cleveland, OH
Background/Purpose: Oral bisphosphonates adherence has been reported as less than 50% at one year. Adherence to denosumab has been reported to be higher than alendronate…
Abstract Number: 2317 • 2014 ACR/ARHP Annual Meeting
Towards Reliable Implementation and Optimal Use of Medication Decision Aid Cards for Shared Decision Making in Juvenile Idiopathic Arthritis
Esi M. Morgan DeWitt¹, Janalee Taylor², Karla B. Jones³, Murray H. Passo⁴, Catherine C. Mims⁴, Jesse Pratt⁵, Ellen A. Lipstein⁶, Nancy Griffin⁷, Sheetal S. Vora⁸, Beth S. Gottlieb⁹, Elizabeth Roth-Wojcicki¹⁰ and William B. Brinkman¹¹, ¹Department of Pediatrics, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²William S. Rowe Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Rheumatology ED 1S, Nationwide Children's Hospital, Columbus, OH, ⁴Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ⁵Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁷James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁸University of North Carolina Chapel Hill, Chapel Hill, NC, ⁹Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ¹⁰Pediatrics, Medical College of Wisconsin, Milwaukee, WI, ¹¹Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose The purpose of the study was to improve communication and shared decision-making (SDM) between clinicians and parents of patients with juvenile idiopathic arthritis (JIA),…
Abstract Number: 2318 • 2014 ACR/ARHP Annual Meeting
Increasing Rates of Remission in Juvenile Idiopathic Arthritis through a Quality Improvement Learning Network – the Pediatric Rheumatology Care and Outcomes Improvement Network
Esi M. Morgan DeWitt¹, Stacy P. Ardoin², C. April Bingham³, Beth S. Gottlieb⁴, Ronald Laxer⁵, Nancy Griffin⁶, Jesse Pratt⁷, Anne Paul⁸, Daniel Lovell⁹, Judyann C. Olson¹⁰, Murray H. Passo¹¹, Jennifer E. Weiss¹², Tzielan C. Lee¹³, Sheetal S. Vora¹⁴, Melissa M. Hazen¹⁵ and Peter Margolis¹⁶, ¹Department of Pediatrics, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ³Penn State Hershey Children's Hospital, Hershey, PA, ⁴Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ⁵Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ⁶James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁷Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁸Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, ¹⁰Medical College of Wisconsin, Milwaukee, WI, ¹¹Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, ¹²Pediatric Rheumatology, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ¹³Pediatric Rheumatology, Stanford University School of Medicine, Stanford, CA, ¹⁴University of North Carolina Chapel Hill, Chapel Hill, NC, ¹⁵Division of Immunology, Boston Children's Hospital, Boston, MA, ¹⁶Clinical Effectiveness, Cincinnati Children's Hospital, Cincinnati, OH
Background/Purpose The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) since 2011 has used quality improvement (QI) methods, chronic illness care model interventions, and a…
Abstract Number: 2319 • 2014 ACR/ARHP Annual Meeting
Standardizing and Documenting Patient Education and Disease Indices in Childhood-Onset Systemic Lupus Erythematosus
Julia G. Harris^1,2, Elizabeth Roth-Wojcicki³, Marsha Malloy⁴, Kristyn I. Maletta⁵, Dominic O. Co^2,3 and Judyann C. Olson¹, ¹Medical College of Wisconsin, Milwaukee, WI, ²Children's Hospital of Wisconsin, Milwaukee, WI, ³Pediatrics, Medical College of Wisconsin, Milwaukee, WI, ⁴Pediatrics Rheumatology, Medical College of Wisconsin, Milwaukee, WI, ⁵National Outcomes Center, Children's Hospital of Wisconsin, Milwaukee, WI
Background/Purpose: Systemic lupus erythematosus (SLE) can affect many organ systems and lead to significant morbidities. Methods to standardize and improve care in this patient…
Abstract Number: 2320 • 2014 ACR/ARHP Annual Meeting
Initial Benchmarking of the Quality of Medical Care of Childhood-Onset Systemic Lupus Erythematosus
Ahmad I. Zaal¹, Rina Mina², Simone Appenzeller³, Julia Harris⁴, Marco F. Silva⁵, Jiha Lee⁶, Prachi Khandekar⁷, Maraisa Centeville³, HaiMei Liu², Joshua D. Pendl², Anne Johnson², Jennifer L. Huggins¹, Raju Khubchandani⁸, Stacy P. Ardoin⁹, Marisa S. Klein-Gitelman¹⁰, Clovis A. Silva¹¹ and Hermine I. Brunner¹², ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil, ⁴Rheumatology, Children's Hospital of Wisconsin, Milwaukee, WI, ⁵Pediatric Rheumatology Unit-Children’s Institute,, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁶Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, ⁷Rhrumatology, Jaslok Hospital and Research Center, Mumbai, India, ⁸Rheumatology, Jaslok Hospital and Research Center, Mumbai, India, ⁹Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ¹⁰Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ¹¹Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ¹²Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Quality indicators (QI) are minimum standards of medical care in support of optimal disease outcomes. In childhood-onset systemic lupus erythematous (cSLE), 26 QI’s, which…
Abstract Number: 2321 • 2014 ACR/ARHP Annual Meeting
Quality Improvement in the Identification of Crystals from Synovial Fluid: Hospital Laboratory Versus Rheumatology Department Evaluation
Joanne Szczygiel Cunha¹, Anthony Reginato² and Stuart Schwartz², ¹Rheumatology, The Warren Alpert School of Medicine at Brown Univeristy, Providence, RI, ²Rheumatology, The Warren Alpert School of Medicine at Brown University, Providence, RI
Background/Purpose It has been well studied and accepted that the best method for evaluating joint disease is examination of synovial fluid. Synovial fluid analysis is…
Abstract Number: 2322 • 2014 ACR/ARHP Annual Meeting
Aim for Better Gout Control: A Retrospective Analysis of Preventable Hospital Admissions for Gout
Tarun S. Sharma¹, Thomas M. Harrington² and Thomas P. Olenginski², ¹Rheumatology, Geisinger Medical Center, Danville, PA, ²Dept of Rheumatology, Geisinger Health System, Danville, PA
Background/Purpose: ACR/EULAR guidelines have been published on the management of gout. Despite these guidelines, many patients with gout suffer recurrent flares and hospitalizations resulting in…
Abstract Number: 2324 • 2014 ACR/ARHP Annual Meeting
Only 30% Rheumatologists Collect Basdai in Patients with Axial Spa in Daily Practice: The Potential Role of a Consensual Meeting to Improve It
Hélène Che^1,2, Adrien Etcheto^2,3, Emmanuelle Dernis Labous^4,5, Henri Nataf⁵, Patrick Boumier⁵, Philippe Breuillard⁵, Marianne Durandin-Truffinet⁵, Jacques Fechtenbaum^2,5, Veronique Gaud-Listrat^2,5, Bernard Giraud⁵, Christophe Hudry^2,5, Sylvain La Batide Alanore⁵, Patricia Le Devic⁵, Patrick Le Goux⁵, Agnes Lebrun^2,5, Emmanuel Maheu⁵, Bertrand Moura⁵, Minh Nguyen^2,5, Antoinette Sacchi⁵, Xavier Ayral^5,6, Anne Blanchais^2,5, Severine Neveu^2,5, Maxime Dougados^2,5,7 and Anna Molto^2,5,7, ¹Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, ²Université Paris René Descartes and Hôpital Cochin, Paris, France, ³Cochin Hospital, Paris Descartes University, Paris, France, ⁴Rhumatologie, Ch Du Mans, Le Mans, France, ⁵Réseau Hôpital et Ville en Rhumatologie (RHEVER) Network, Paris, France, ⁶Université Paris René Descartes and Hôpital Cochin, paris, France, ⁷INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France., Paris, France
Background/Purpose The current recommendations for optimal monitoring of axial spondyloarthritis (SpA) are to assess regularly disease activity. The two proposed tools comprise clinical aspects as…

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