Abstract Number: 296 • 2015 ACR/ARHP Annual Meeting
Different Patterns of Involvement of Thigh Muscles in Dermatomyositis and Polymyositis Using Fat-Suppressed Magnetic Resonance Sequences
Background/Purpose: MRI is often used to evaluate muscle inflammation in myositis. Muscle edema on fat-suppressed (short tau inversion recovery, STIR) sequences is thought to represent…Abstract Number: 297 • 2015 ACR/ARHP Annual Meeting
How Useful Is Magnetic Resonance Imaging (MRI) in Monitoring Patients with Myositis?
Background/Purpose: MRI is commonly used to assess muscle inflammation in myositis. Muscle edema on fat-suppressed sequences is thought to reflect active inflammation. However, it is…Abstract Number: 298 • 2015 ACR/ARHP Annual Meeting
Investigating the Pathogenic Role of ER Stress Pathway Activation in the Idiopathic Inflammatory Myopathies (IIM): Skeletal Muscle Cells As a Source of Cytokines (Myokines)
Background/Purpose: The idiopathic inflammatory myopathies (IIM) are a collection of autoimmune disorders, characterised by the development of debilitating symmetrical skeletal muscle weakness. IIM Patients also…Abstract Number: 299 • 2015 ACR/ARHP Annual Meeting
Subcutaneous Edema, Distal Weakness and Dysphagia Associated with the NXP2 Antibody
Background/Purpose: Myositis specific antibodies are known to be associated with specific phenotypes. The unusual presentation of subcutaneous edema, distal weakness and dysphagia was seen in…Abstract Number: 300 • 2015 ACR/ARHP Annual Meeting
Causes of Creatine Kinase Levels Greater Than 1,000 IU/L in Patients Referred to Rheumatology
Background/Purpose: Patients with significantly elevated creatine kinase (CK) levels are commonly referred to rheumatologists to evaluate for the presence of an idiopathic inflammatory myopathy (IIM).…Abstract Number: 301 • 2015 ACR/ARHP Annual Meeting
Economic Burden of Sporadic Inclusion Body Myositis in the United States of America: A Retrospective Cohort Study
Background/Purpose: Sporadic inclusion body myositis (sIBM) is a rare & debilitating muscle disease characterized by the slow progressive asymmetric weakness, atrophy of proximal & distal…Abstract Number: 302 • 2015 ACR/ARHP Annual Meeting
Resource Utilization in a US Sample of Patients with Sporadic Inclusion Body Myositis
Background/Purpose: Sporadic Inclusion Body Myositis (sIBM) is a progressive, idiopathic inflammatory myopathy characterized by dysphagia, weakness of proximal and distal muscles and atrophy. This cross-sectional…Abstract Number: 303 • 2015 ACR/ARHP Annual Meeting
Mining RNA-Seq of Peripheral Blood Mononuclear Cells from JDM Alone Compared with JDM Plus Psoriasis for Biomarkers of Disease Activity
Background/Purpose: Our CureJM JDM Registry/Repository contains sequential samples of peripheral blood mononuclear cells (PBMCs) and sera obtained every 6 months from over 467 children with…Abstract Number: 304 • 2015 ACR/ARHP Annual Meeting
Abnormal Pulmonary Function Tests, Interstitial Lung Disease, and Lung Function Decline in Patients with Classic and Clinically Amyopathic Dermatomyositis
Background/Purpose: Interstitial lung disease (ILD) is common in classic dermatomyositis (DM) and clinically amyopathic dermatomyositis (CADM), in which rash is present without weakness. Previous studies…Abstract Number: 305 • 2015 ACR/ARHP Annual Meeting
The “Sleeve Sign”� in Dermatomyositis
Background/Purpose: Dermatomyositis (DM) is a subset of idiopathic inflammatory myopathies, characterized by proximal skeletal muscle weakness and skin manifestations. Several skin eruptions have been described…Abstract Number: 306 • 2015 ACR/ARHP Annual Meeting
Investigating the Pathogenic Role of ER Stress Pathways in the Idiopathic Inflammatory Myopathies (IIM): Interrogating the Role of Micro-RNA 133a As an Important Regulator of ER Stress Activation
Background/Purpose: The Idiopathic Inflammatory Myopathies (IIM) is a heterogeneous group of acquired autoimmune disorders, characterised by symmetrical muscle weakness. Whilst immune cells clearly play a…Abstract Number: 307 • 2015 ACR/ARHP Annual Meeting
Screening for Pulmonary Hypertension in the Anti-Synthetase Syndrome; Utility of Four Different Screening Approaches
Background/Purpose: Pulmonary hypertension (PH) is a feared complication of the anti-synthetase syndrome (ASS) and has previously been reported to occur in 8% of the patients…Abstract Number: 308 • 2015 ACR/ARHP Annual Meeting
Nailfold Capillaroscopy in Patients with Early Onset-Dermatomyositis
Background/Purpose: Nailfold capillaroscopy (NC) has been demonstrated to be an important tool in the treatment of patients with juvenile dermatomyositis (JDM) and systemic sclerosis. However,…Abstract Number: 309 • 2015 ACR/ARHP Annual Meeting
Plasma Levels of Heat Shock Protein 90 Are Increased in Idiopathic Inflammatory Myopathies and Correlate with Disease Activity, Skeletal Muscle, Heart and Lung Involvement
Background/Purpose: Heat shock proteins (Hsps) are chaperones playing important roles in skeletal muscle physiology, adaptation to exercise or stress, and in activation of inflammatory cells.…Abstract Number: 310 • 2015 ACR/ARHP Annual Meeting
Hyaluronic Acid Injections in Knee Osteoarthritis Patients Are Associated with Delay to Knee Arthroplasty
Background/Purpose: Although only few nonoperative treatment options for knee osteoarthritis (OA) are available, there continues to be debate about the effectiveness of hyaluronic acid (HA)…
ACR Meeting Abstracts