ACR Meeting Abstracts

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  • Abstract Number: 0350 • ACR Convergence 2023

    Presentation, Management, and Outcomes of Systemic JIA-Associated Lung Disease: A Single Center Experience

    Ana Luiza Altaffer1, Maria Pereira2, Marietta De Guzman2 and Andrea Ramirez2, 1Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Baylor College of Medicine, Houston, TX

    Background/Purpose: Interstitial lung disease (ILD) is a rare and severe complication of systemic juvenile idiopathic arthritis (SJIA) that was recognized relatively recently, and its incidence…
  • Abstract Number: 0353 • ACR Convergence 2023

    Validation of Claims-based Algorithms for Newly Diagnosed Juvenile Idiopathic Arthritis Using Machine Learning Methods

    Patricia Hoffman1, Lauren Parlett2, Daniel Beachler2, Daniel Reiff3, Sarah McGuire1, Sonia Pothraj1, Lakshmi Moorthy1, Cynthia Salvant4, Dawn Koffman5, Sanika Rege5, Cecilia Huang5, Matthew Iozzio5, Kevin Schott2, Kevin Haynes6, Amy Davidow7, Stephen Crystal8, Tobias Gerhard5, Brian Strom9, Carlos Rose10 and Daniel Horton4, 1Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 2Carelon, Wilmington, DE, 3University of Alabama at Birmingham, Birmingham, AL, 4Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 5Rutgers Center for Pharmacoepidemiology and Treatment Science, New Brunswick, NJ, 6Janssen Pharmaceuticals, Raritan, NJ, 7New York University, New York, NY, 8Rutgers University, New Brunswick, NJ, 9Rutgers, State University of New Jersey, New Brunswick, NJ, 10Thomas Jefferson University, Philadelphia, PA

    Background/Purpose: Administrative claims databases represent important settings for studying large populations with juvenile idiopathic arthritis (JIA), but prior efforts to validate diagnostic algorithms for JIA…
  • Abstract Number: 0278 • ACR Convergence 2023

    NOD2 Genotyping Landscape in Yao Syndrome

    Hafsa Nomani1, Ashmia Saif2, Frank Hwang1 and Qingping Yao1, 1Stony Brook University, Stony Brook, NY, 2Stony Brook University Hospital, Syosset, NY

    Background/Purpose: Yao syndrome (YAOS, OMIM 617321) is formerly designated NOD2-associated autoinflammatory disease. A spectrum of NOD2 mutations have been associated with this disease. This study…
  • Abstract Number: 0348 • ACR Convergence 2023

    The Use of Ruxolitinib for Improved Disease Control in Systemic Juvenile Idiopathic Arthritis (sJIA) and Recurrent Macrophage Activation Syndrome (MAS)

    Kathleen Collins1, Iman Abutineh1, Trisha Paul2, Parul Rai3, Grant Schulert4 and Melissa Hines2, 1University of Tennessee Health Science Center, Memphis, TN, 2St Jude Children's Research Hospital, Memphis, TN, 3St Jude Children's Reseaerch Hospital, Memphis, TN, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: The advent of biologics such as IL-1 receptor antagonists has dramatically improved outcomes for children with pediatric rheumatic diseases and hyperinflammation. However, there remains…
  • Abstract Number: 0357 • ACR Convergence 2023

    Validation of the Juvenile Spondyloarthritis Disease Activity Index in a Prospective Clinical Trial Setting

    Pamela F. Weiss1, Nicolino Ruperto2, Erhard Quebe-Fehling3, Alexis Shew4, Luminita Pricop5, Christelle Pieterse3 and Hermine Brunner6, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2IRCCS Istituto Giannina Gaslini, UOSID Centro Trial, Genova, Italy, 3Novartis Pharma AG, Basel, Switzerland, 4Novartis Pharmaceuticals Corporation, St. Louis, MO, 5Novartis Pharmaceuticals Corporation, East Hanover, NJ, 6Cincinnati Children's Hospital Medical Center, Division of Rheumatology, Cincinnati, OH

    Background/Purpose: The juvenile spondyloarthritis disease activity index (JSpADA) is a disease activity assessment tool developed for children with juvenile psoriatic arthritis (JPsA) and enthesitis related…
  • Abstract Number: 0360 • ACR Convergence 2023

    Increasing the Etanercept Dose in Juvenile Idiopathic Arthritis Patients: Does It Help Reaching the Treatment Target? A Post-hoc Analysis of the Best4Kids Randomised Clinical Trial

    Bastiaan van Dijk1, Sytske Anne Bergstra1, Merlijn van den Berg2, Dieneke Schonenberg-Meinema2, Lisette van Suijlekom-Smit2, Marion van Rossum3, Yvonne Koopman4, Rebecca Ten Cate1, CF Allaart1, Danielle Brinkman1 and Petra Hissink Muller1, 1Leiden University Medical Center, Leiden, Netherlands, 2Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, Netherlands, 3Amsterdam Rheumatology and Immunology Center | Reade, Amstelveen, Netherlands, 4HagaZiekenhuis Juliana Children's Hospital, The Hague, Netherlands

    Background/Purpose: The relation between etanercept dose and clinical outcomes of juvenile idiopathic arthritis (JIA) is unclear. Most studies only evaluated doses up to 0.8 mg/kg/week…
  • Abstract Number: 0364 • ACR Convergence 2023

    Sex Differences in Clinical and Imaging Characteristics of Axial Juvenile Spondyloarthritis

    Adam Mayer1, Timothy G. Brandon2, Pamela F. Weiss3 and on behalf of the JAXSPERT members2, 1University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: The extent to which heterogeneity exists in youth with axial disease and juvenile spondyloarthritis (JSpA) is unclear. In a cross-sectional sample of patients classified…
  • Abstract Number: 0308 • ACR Convergence 2023

    Burden of Osteoarthritis Attributable to High BMI in 38 OECD Countries: A Benchmarking Analysis

    Dhruvkumar Gadhiya1, Utsav Patel2, Hiren Chhayani3, Krushi Shah3, Sneh Patel3, Victor Adedara4, Divya Patel3 and Hardik Desai5, 1St.Luke's University Health, Anderson Campus, Easton, PA, 2Tulane University, New Orleans, LA, 3G.M.E.R.S. Medical College, Gandhinagar, Gandhinagar, India, 4St George’s University SOM, True Blue Greneda, True Blue, Grenada, 5Gujarat Adani Institute of Medical Sciences, Bhuj, India., Bhuj, India

    Background/Purpose: The burden of osteoarthritis related to high body mass index (BMI) in OECD countries is a significant public health concern. Osteoarthritis is strongly associated…
  • Abstract Number: 0314 • ACR Convergence 2023

    Lack of Systemic Effects from Intra-articular XT-150 for the Treatment of Moderate to Severe Pain Due to OA of the Knee: Safety Results from a Phase 2 Trial

    Leonard Kapural1, Stephen D. Collins2, Eric Grigsby3, Mark McBride4, Jayson Rieger5, Morgan Stokes6, Howard Rutman6 and Flavia Cicuttini7, 1Center for Clinical Research, Winston-Salem, NC, 2Xalud Therapeutics, Inc., Chicago, IL, 3Neurovations Clinical Research, Napa, CA, 4Instat Clinical Research, Chatham, NJ, 5PBM Capital, Charlottesville, VA, 6Xalud Therapeutics, Inc., Berkeley, CA, 7Monash University, Melbourne, Australia

    Background/Purpose: This study (NCT04124042) was designed to assess the safety, tolerability, and efficacy of XT-150, a non-viral gene therapy, in adult participants with moderate to…
  • Abstract Number: 0310 • ACR Convergence 2023

    Implementing an Osteoarthritis Management Program to Deliver Guideline-Driven Care for Knee and Hip Osteoarthritis in a U.S. Academic Health System

    Kathryn Miller1, Divya Vundamati2, Linda Baier1, Roger Brown1, Tommy Yue Yu1 and Christie M. Bartels3, 1University of Wisconsin, Madison, WI, 2UW Health, Madison, WI, 3University of Wisconsin, School of Medicine and Public Health, Madison, WI

    Background/Purpose: To assess patient outcomes from an Osteoarthritis Management Program (OAMP) situated in an academic medical center.Methods: Eligibility for this open cohort study included adults…
  • Abstract Number: 0321 • ACR Convergence 2023

    Use of Proton Pump Inhibitors and Risk of Hip/knee Joint Replacement Among Patients with Osteoarthritis and Rheumatoid Arthritis

    Koushik Sangaraju1, Radu Grovu2, Michael Kwark2, Elizabeth Cohen2, Amira Hassan3 and Anastasia Slobodnick2, 1Staten Island University Hospital - Northwell Health, Staten Island, NY, 2Northwell Health, Staten Island, NY, 3Northwell Health, Brooklyn, NY

    Background/Purpose: Osteoarthritis and rheumatoid arthritis cause significant joint replacement morbidity. Proton pump inhibitors (PPIs) may contribute to chronic inflammation and joint degeneration due to side…
  • Abstract Number: 0331 • ACR Convergence 2023

    Assessment of Patient Adherence to “Sick Day Rules”: A Cross-sectional Study of Rheumatology Outpatients Prescribed Immunosuppressive Medications

    Mervè Aksoy1, Pamela Gonzalez Manrique2, Heinrich-Karl Greenblatt1 and Katarzyna Gilek-Seibert1, 1Roger Williams Medical Center, Providence, RI, 2Roger Williams Medical Center, North Providence, RI

    Background/Purpose: Rheumatology outpatients receiving immunosuppressive medications (IS) inevitably develop acute infections. Expert guidance, in accordance with usual clinical practice, recommends counseling patients on “sick day…
  • Abstract Number: 0334 • ACR Convergence 2023

    Association of a Self-Report Screening Tool for Sarcopenia (SARC-F) with Functional Status Outcomes in Systemic Lupus Erythematosus

    Sarah Lieber1, Yvonne Shea2, Deanna Jannat-Khah2, John Carrino2, M. Carrington Reid3 and Lisa Mandl1, 1Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Weill Cornell Medicine, New York, NY

    Background/Purpose: Sarcopenia, i.e., loss of skeletal muscle mass and strength, has been associated with multiple adverse health outcomes, including mortality. Although limited data suggest that…
  • Abstract Number: 0339 • ACR Convergence 2023

    Longitudinal Glucocorticoid Toxicity in Rheumatic Disease Patients (LONG-TOX) and Associations with Quality of Life and Healthcare Resource Utilization: Interim Analysis from a Prospective Cohort

    Naomi Patel1, Aubree McMahon1, Grace McMahon1, Sebastian Perez-Espina1, Isha Jha1, Adam Jarvie1 and John Stone2, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Concord, MA

    Background/Purpose: Glucocorticoids (GCs) continue to be the cornerstone of therapy for many rheumatic diseases, though long-term exposure to GCs has been linked to dozens of…
  • Abstract Number: 0341 • ACR Convergence 2023

    Patient Perspectives on the Usability of a Rheumatoid Arthritis Patient-reported Outcomes Electronic Health Record-based Dashboard: A Mixed-Methods Study

    Cherish Wilson1, Catherine Nasrallah2, Alicia Hamblin2, Lindsay Jacobsohn2, Cammie Young3, Cammie Young3, Mary Nakamura4, Andrew Gross2, Judith Ashouri2, Brett Dietz2, Mehrdad Matloubian2, Jinoos Yazdany5 and Gabriela Schmajuk1, 1UCSF / SFVA, San Francisco, CA, 2University of California San Francisco, San Francisco, CA, 3University of California San Francisco, Oakland, CA, 4UCSF/SFVAHCS, San Francisco, CA, 5University of California, General Department of Medicine, Division of Rheumatology, San Francisco, CA

    Background/Purpose: Shared decision making, health literacy, and effective communication around patient-reported outcomes (PROs) are vital components to a treat-to-target approach in rheumatoid arthritis (RA) patients.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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