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  • Abstract Number: 234 • 2015 ACR/ARHP Annual Meeting

    Weight Variables and Their Association with Serum Urate Concentrations and Hyperuricemia in Young Adults

    Angelo L. Gaffo1,2, David R. Jacobs Jr.3, Huifen Wang4 and Kenneth G. Saag5, 1Rheumatology, Birmingham VA Medical Center, Birmingham, AL, 2Medicine, University of Alabama at Birmingham, Birmingham, AL, 3Epidemiology, University of Minnesota, Minneapolis, MN, 4Nutritional Epidemiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, 5University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: How body weight, anthropometric parameters, and their changes are associated with serum urate concentrations and hyperuricemia remains unclear. The CARDIA study has been following…
  • Abstract Number: 235 • 2015 ACR/ARHP Annual Meeting

    Relationship Between Tissue Stress during Gait and Patterns of Urate Deposition and Bone Erosion in Gout: A Biomechanical Computational Modelling Study

    Nicola Dalbeth1, Michelle Deacon2, Gregory Gamble1, Kumar Mithraratne2 and Justin Fernandez2, 1Department of Medicine, University of Auckland, Auckland, New Zealand, 2University of Auckland, Auckland, New Zealand

    Background/Purpose: Gout typically presents at characteristic sites such as the 1st metatarsophalangeal joint, midfoot or ankle. A potential explanation for this distribution is that tissue…
  • Abstract Number: 236 • 2015 ACR/ARHP Annual Meeting

    Foot and Ankle Muscle Strength in People with Gout: A Two-Arm Cross-Sectional Study

    Sarah Stewart1, Grant Mawston2, Lisa Davidtz3, Nicola Dalbeth4, Alain Vandal5, Matthew Carroll3, Trish Morpeth6, Simon Otter7 and Keith Rome8, 1School of Podiatry, Auckland University of Technology, Auckland, Niger, 2Department of Physiotherapy, Auckland University of Technology, Auckland, New Zealand, 3School of Podiatry, Auckland University of Technology, Auckland, New Zealand, 4Department of Medicine, University of Auckland, Auckland, New Zealand, 5Counties Manukau District Health Board, Auckland, New Zealand, 6Auckland University of Technology, Auckland, New Zealand, 7School of Health Professions, University of Brighton, Brighton, England, 8Health & Research Rehabilitation Centre, AUT University, Auckland, AR, New Zealand

    Background/Purpose: Foot and ankle structures are commonly affected in gout. People with gout experience difficulty walking and report high levels of foot pain, disability and…
  • Abstract Number: 237 • 2015 ACR/ARHP Annual Meeting

    The Prevalence of Chondrocalcinosis of the Symphysis Pubis on CT Scan and Correlation with Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

    Trusha Patel1, Lawrence Ryan2, Melissa DuBois3, Guillermo Carrera3, Keith Baynes3, Rajeev Mannem3 and Jennifer Mulkerin3, 1Rheumatology, Medical College of Wisconsin, Milwaukee, WI, 2Department of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, 3Radiology, Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Calcium pyrophosphate dihydrate  (CPP) crystal deposition in articular cartilage can often be seen radiographically as chondrocalcinosis (CC). CPP crystals preferentially deposit in fibrocartilages such…
  • Abstract Number: 238 • 2015 ACR/ARHP Annual Meeting

    Relationship Between Ultrasonographic Synovial Inflammation  and Ultrasonographic Urate Deposition Findings in Patients with Gout

    Fernando Perez-Ruiz1,2, Sandra P. Chinchilla-Gallo3, Irati Urionagüena4 and Elena Garmendia3,5, 1Rheumatology Division, Hospital Universitario Cruces, Barakaldo, Spain, 2BioCruces Health Research Institute, Baracaldo, Spain, 3Rheumatology Division, Hospital Universitario Cruces, Baracaldo, Spain, 4Rheumatology Division, Hospital Universitario ruces, Baracaldo, Spain, 5Biocruces Helath Research Institute, Baracaldo, Spain

    Background/Purpose: urate intra-articular deposits are seen in ultrasound as double contour sign (DCS), and hyperechogenic aggregates and tophi, but the extent of contribution of any…
  • Abstract Number: 239 • 2015 ACR/ARHP Annual Meeting

    The Role of Dual Energy Computed Tomography in Diagnosing Acute Gouty Arthritis: Comparison with Ultrasound and Aspiration

    Jennifer Lee1, Ji Yeon Lee2, Jung Hee Koh3, Min Kyung Chung4, Ji Hun Kim1, Seung-Ki Kwok5, Ji Hyeon Ju6 and Sung-Hwan Park7, 1Division of Rheumatology, Department of Internal Medicine, College of Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea, 2Division of Rheumatology, Department of Internal Medicine, School of Medicine, Catholic University of Korea, Seoul St. Mary’s Hospital, Seoul, South Korea, 3Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, 4Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary’s Hospital, Seoul, South Korea, 5Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea, 6Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, 7Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Background/Purpose: The gold standard of acute gouty arthritis diagnosis has been to verify the presence of monosodium urate (MSU) crystal in the aspirated fluid of…
  • Abstract Number: 240 • 2015 ACR/ARHP Annual Meeting

    Volumetric Assessment of Tophaceous Gout

    Ralf G. Thiele1, Laura Coates2 and Darren Tabechian1, 1University of Rochester Medical Center, Rochester, NY, 2Medicine, University of Rochester, Rochester, NY

    Background/Purpose: Ultrasound (US) can identify monosodium urate (MSU) tophi within joints, tendons, bursae and other soft tissues. The ability to readily, quickly and inexpensively assess…
  • Abstract Number: 241 • 2015 ACR/ARHP Annual Meeting

    Inflammatory Syndrome in Polyarticular Gout – Description of a Previously Neglected Entity

    Valentin S. Schäfer1, Andreas Krause2 and Wolfgang A. Schmidt2, 1Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch, Berlin, Germany, 2Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany

    Background/Purpose: Inflammatory polyarticular gout occurs in clinical practice. However, only very few single case reports have been published as yet. This case series aims at…
  • Abstract Number: 242 • 2015 ACR/ARHP Annual Meeting

    Higher Serum Uric Acid Levels Are Associated with an Increased Risk of Flares: A Systematic Review

    Aki Shiozawa1, Shelagh M Szabo2, Antoinette Cheung2, Anna Bolzani2 and Hyon K. Choi3, 1Global Outcomes and Epidemiology Research, Takeda Pharmaceuticals International, Inc, Deerfield, IL, 2Redwood Outcomes, Vancouver, BC, Canada, 3Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Acutely painful flares represent the typical clinical burden of gout. Effective therapy can reduce serum uric acid (sUA) levels; however, epidemiologic evidence for the…
  • Abstract Number: 243 • 2015 ACR/ARHP Annual Meeting

    Increase in Risk of Future Attacks in Patients with Incident Gout: A Population-Based Study over 20 Years

    Nour Zleik1, Mohanad Elfishawi1, Zoran Kvrgic1, Clement J. Michet Jr.2, Cynthia S. Crowson3, Eric L. Matteson4 and Tim Bongartz1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose: While there appears to be consensus that non-pharmacological uric acid lowering therapies (diet and lifestyle modifications) should be initiated in every patient presenting with…
  • Abstract Number: 244 • 2015 ACR/ARHP Annual Meeting

    Hospitalization and Flare Risk in Patients with Established Gout: A Population-Based Study

    Nour Zleik1, Mohanad Elfishawi1, Zoran Kvrgic1, Clement J. Michet Jr.2, Cynthia S. Crowson3, Eric L. Matteson4 and Tim Bongartz1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose: Hospitalization of patients with gout may be associated with an increased risk of arthritic flares, due to administration of IV fluids, discontinuation of established…
  • Abstract Number: 245 • 2015 ACR/ARHP Annual Meeting

    Seasonal Variation in Acute Gouty Arthritis: Data from Nationwide Inpatient Sample

    Paras Karmacharya1, Ranjan Pathak2, Madan Aryal2, Smith Giri3 and Anthony Donato4, 1Internal Medicine, Reading Health System, WEST READING, PA, 2Internal medicine, Reading Health System, West Reading, PA, 3Internal medicine, University of Tennessee Health Science Center, Memphis, TN, 4Internal, Reading Health System, Salt Lake, UT

    Background/Purpose: Studies describing seasonal variations in acute gouty arthritis note a seasonal trend, but disagree on timing, with most showing a peak in spring months…
  • Abstract Number: 246 • 2015 ACR/ARHP Annual Meeting

    Adult Autoinflammatory Disease Frequency and Our Diagnostic Experience in an Adult Autoinflammatory Clinic

    Qingping Yao1, Felicitas Lacbawan2 and Jianbo Li1, 1Cleveland Clinic, Cleveland, OH, 2Molecular Genetics Pathology, Cleveland Clinic, Cleveland, OH

    Background/Purpose: Autoinflammatory diseases (AIDs), aka, periodic fever syndromes include monogenic diseases, such as familial Mediterranean fever (FMF), cryopyrin-associated periodic disease (CAPS), tumor necrosis factor receptor-associated…
  • Abstract Number: 247 • 2015 ACR/ARHP Annual Meeting

    Severe Inflammation Following Vaccination Against Streptococcus Pneumoniae in Patients with Cryopyrin-Associated Periodic Syndromes

    Ulrich A. Walker1,2, Philip N. Hawkins3, Rene Williams4, Hal M. Hoffman5 and Jasmin B. Kuemmerle-Deschner6, 1Rheumatology, Unispital Basel, Basel, Switzerland, 2Rheumatology, University Hospital, Basel, Basel, Switzerland, 3University College London Medical School, London, United Kingdom, 4University College, London, England, 5University of California at San Diego, San Diego, CA, 6Universitätsklinikum Tübingen, Klinik fuer Kinder- und Jugendmedizin, Tübingen, Germany

    Background/Purpose: Pneumococcal vaccination is recommended for patients requiring treatment with immunosuppressive drugs. The aim of this report is to describe unusually severe adverse reactions to…
  • Abstract Number: 248 • 2015 ACR/ARHP Annual Meeting

    Efficacy and Safety of Canakinumab in Patients with CAPS Aged <24 Months: Results from an Open-Label, Multicenter, Phase III Trial

    Paul Brogan1, Michaël Hofer2, Jasmin B. Kuemmerle-Deschner3, Bernard R. Lauwerys4, Antonio Speziale5, K. Abrams6, Karolynn Leon7, Xiaoling Wei8 and Ronald Laxer9, 1Department of Paediatric Rheumatology, UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom, 2Unité Romande de Rhumatologie Pédiatrique, Hospitalier Universitaire Vaudois, Lausanne, Switzerland, 3University Hospital Tuebingen, Tuebingen, Germany, 4Cliniques Universitaires Saint-Luc and Université Catholique de Louvain, Brussels, Belgium, 5Novartis Pharma AG, Basel, Switzerland, 6Novartis Pharmaceutical Corporation, East Hanover, NJ, 7Novartis Pharmaceuticals Corporation, East Hanover, NJ, 8Novartis Pharma, Beijing, NU, China, 9University of Toronto, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Canakinumab (CAN) is indicated for the treatment of cryopyrin-associated periodic syndrome (CAPS) in patients aged ≥2 years.1,2 However, the efficacy of CAN has not…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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