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  • Abstract Number: 2597 • 2014 ACR/ARHP Annual Meeting

    Impact of Repeating Imaging of the Sacro-Iliac Joints over One Year on the Classification According the ASAS Axial Spa Criteria of Patients

    Pauline Bakker1, Manouk de Hooge1, Rosaline van den Berg2, Floris van Gaalen2, Monique Reijnierse1, T.W.J. Huizinga1 and Désirée van der Heijde3, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: It is known that in axial spondyloarthritis (axSpA) inflammatory lesions on MRI of the SI joints (MRI-SI) can change over time. The usefulness of…
  • Abstract Number: 2596 • 2014 ACR/ARHP Annual Meeting

    Similarities and Differences Between Axial and Peripheral Predominant Forms in patients with Early Spondyloarthritis (SpA): Results from the Esperanza Cohort

    Pilar del Río-Martínez1, Victoria Navarro-Compán2, Concepción Castillo-Gallego3, M. Carmen Castro4, Eduardo Collantes-Estévez4 and Eugenio De Miguel3, 1Rheumatology,, Rheumatologist, Zaragoza, Spain, 2Rheumatology, Rheumatologist, Madrid, Spain, 3Rheumatology,, Rheumatologist, Madrid, Spain, 4Rheumatology, Rheumatologist, Córdoba, Spain

    Background/Purpose: Based on the predominant manifestation of the disease, the ASAS classification criteria for spondyloarthritis (SpA) distinguish two clinical forms: •Axial SpA, including non-radiographic SpA…
  • Abstract Number: 2595 • 2014 ACR/ARHP Annual Meeting

    Using Iphone Compass Application for the Assessment of Cervical Rotation in Patients with Ankylosing Spondylitis

    Gokce Kenar, Berrin Zengin, Handan Yarkan, Pinar Cetin, Ismail Sari, Fatos Onen, Merih Birlik and Nurullah Akkoc, Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey

    Background/Purpose Cervical rotation reflects restriction of mobility in axial disease in ankylosing spondylitis (AS) and it can be assessed in several approaches based on the…
  • Abstract Number: 2594 • 2014 ACR/ARHP Annual Meeting

    Differences in Localization and Activity of the Entheseal Involvement Between Non-Radiographic and Radiographic Axial Spondyloarthritis By the Ultrasound Assessment

    Marketa Fojtikova1, Karel Pavelka1, Sarka Forejtova2 and Jindra Gatterova3, 1Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 2Rheumatology, Institute of Rheumatology, Prague, Czech Republic, 3Institute of rheumatology, Prague 2, Czech Republic

    Background/Purpose Inflammatory involvement of peripheral enthesis belongs to an important sign of spondyloarthritis (SpA). It may occur in patients with long-term as well as newly…
  • Abstract Number: 2613 • 2014 ACR/ARHP Annual Meeting

    Positive Spine MRI for Inflammation Predicts Radiographic Progression in Patients with Ankylosing Spondylitis

    Walter P. Maksymowych1, S Wichuk2, Z Zhao3, P Chiowchanwisawakit4, RG Lambert5 and Sj Pedersen6, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Department of Medicine, University of Alberta, Edmonton, AB, Canada, 3PLA General Hospital, Beijing, China, 4Mahidol University, Bangkok, Thailand, 5Radiology, University of Alberta, Edmonton, AB, Canada, 6Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark

    Background/Purpose: Inflammation at vertebral corners on MRI has been shown to predict development of syndesmophytes in patients with AS. However, it is unclear at a…
  • Abstract Number: 2612 • 2014 ACR/ARHP Annual Meeting

    Different Performance of the Major Disease Activity Measures ASDAS and Basdai in Patients with Axial Spondyloarthritis Treated with Non-Steroidal Anti-Inflammatory Agents – Results from a Prospective Study

    Xenofon Baraliakos1, Uta Kiltz1, Frank Heldmann1, Heiner Appel2, Friedrich Dybowski3, Manfred Igelmann4, Ludwig Kalthoff5, Dietmar Krause6, Hans-Jürgen Menne7, Ertan Saracbasi8, Elmar Schmitz-Bortz9 and Jürgen Braun1, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumatology and Nephrology Practice, Hamm, Germany, 3Rheumatology Practice, Herne, Germany, 4Rheumatology Practice, Bochum, Germany, 5Rheumatology practice, Herne, Germany, 6Rheumatology practice, Gladbeck, Germany, 7Rheumatology practice, Dortmund, Germany, 8Rheumatology practice, Oberhausen, Germany, 9Rheumatology practice, Hattingen, Germany

    Background/Purpose: The ASAS/EULAR recommendations for the management of patients (pts) with axial spondyloarthritis (axSpA) have established non-steroidal anti-inflammatory agents (NSAIDs) as first choice of medical…
  • Abstract Number: 2611 • 2014 ACR/ARHP Annual Meeting

    Short Term Efficacy of Tumor Necrosis Factor Inhibitors in Patients with non–radiographic Axial Spondylarthritis and  ankylosing  Spondylitis; Results from Turkbio Registry

    Pinar Cetin1, Umut Kalyoncu2, Bunyamin Kisacik3, Ismail Sari1, Dilek Solmaz4, Omer Karadag2, Ahmet Mesut Onat3, Gezmis Kimyon5, Levent Kilic6, Fatos Onen1, Sedat Kiraz2, Merih Birlik1, Ihsan Ertenli2, Omer Nuri Pamuk7 and Nurullah Akkoc1, 1Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey, 2Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey, 3Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 4Department of Internal Medicine, Division of Rheumatology, Namik Kemal University School of Medicine, Tekirdag, Turkey, 5Department of Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 6Rheumatology, HacettepeUniversity School of Medicine, Ankara, Turkey, 7Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey

    Background/Purpose Axial spondylarthritis (AxSpA) has been proposed as an umbrella term for ankylosing spondylitis (AS) and non-radiographic (nr) AxSpA). This new concept makes diagnosis of…
  • Abstract Number: 2610 • 2014 ACR/ARHP Annual Meeting

    The Role of IL-20 in the Pathogenesis of Ankylosing Spondylitis with Peripheral Joint Involvement

    Göksal Keskin1, Baris Mavi2, Lale Ozisik3, Rahsan Ilikci4 and Mehmet Yildiz2, 1Immunology, Medical School of Ankara, Ankara, Turkey, 2Internal Medicine, Diskapi Training and Research Hospital, Ankara, Turkey, 3Internal Medicine, MD, Ankara, Turkey, 4Basic Immunology, BC, Ankara, Turkey

    Background/Purpose The interleukin-20 (IL-20) is a pro-inflammatory cytokine of the IL-10 family and sequence amino acid is very similar. It has been reported to be…
  • Abstract Number: 2609 • 2014 ACR/ARHP Annual Meeting

    Treating Axial-Spa to Target: Prevalence of Ankylosing Spondylitis Disease Activity Score (ASDAS) Inactive Disease in a Cohort of Patients Treated with Anti-TNFα Agents

    Sara Monti1, Silvia Breda2, Francesca De Nard2, Vittorio Grosso3, Monica Todoerti2, Carlomaurizio Montecucco4 and Roberto Caporali5, 1Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy, 2Division of Rheumatology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy, 3Division of Rheumatology, University of Pavia, Foundation IRCCS Policlinico S. Matteo, Pavia, Italy, 4Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy, 5Division of Rheumatology, Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy

     Background/Purpose . Treating disease to target is emerging as the recommended strategy also in the management of axial-SpA (axSpA) (1).  Reaching remission, defined as inactive…
  • Abstract Number: 2608 • 2014 ACR/ARHP Annual Meeting

    Do You Assess Gastro-Intestinal Auto-Antibodies and Symptoms in Patients with Spondyloarthritis?

    Consuelo Romero Sanchez1,2,3, Wilson Bautista-Molano4, Viviana Parra-Izquierdo5, Carlos Martínez6, Ferney Garcia6, Juliette De Avila7, Haroldo Juliao8, Juan Manuel Bello3, John Londoño9 and Rafael Valle-Oñate9,10, 1Rheumatology, Spondyloarthritis Group. Rheumatology Department. Hospital Militar Central/Universidad de La Sabana. Bogotá. Colombia, Bogotá, Colombia, 2UIBO Institute (Oral Basic Research Unit) School of Dentistry Universidad El Bosque, School of Dentistry, Colombia, Bogotá, Colombia, 3Faculty of Medicine, Universidad Militar Nueva Granada, Bogotá, Colombia, 4Department of Rheumatology, Faculty of Medicine, Universidad Militar Nueva Granada, Bogotá, Colombia, 5Spondyloarthritis Group. Rheumatology Department. Hospital Militar Central/Universidad de La Sabana. Bogotá. Colombia, Bogota, Colombia, 6Coloproctology, Coloproctology Deparment, Hospital Militar Central, Bogotá, Colombia, 7School of Dentistry, UIBO Institute (Oral Basic Research Unit) School of Dentistry Universidad El Bosque, Bogotá, Colombia, 8Gastroenterology, Gastroenterology Deparment, Hospital Militar Central, Bogotá, Colombia, 9Spondyloarthritis Group. Rheumatology Department. Hospital Militar Central/Universidad de La Sabana. Bogotá. Colombia, Bogotá, Colombia, 10Rheumatology, Faculty of Medicine, Universidad Militar Nueva Granada, Bogotá, Colombia

    Background/Purpose Spondyloarthritis (SpA) are a group of chronic inflammatory rheumatic diseases. Extra-articular manifestations affect approximately 30% of patients with SpA, and gastrointestinal manifestations (GI) represents…
  • Abstract Number: 2607 • 2014 ACR/ARHP Annual Meeting

    Fatigue in Ankylosing Spondylitis: A Multivariable Analysis Implicates Inflammation As the Key Determinant of Disability

    Mohamed Bedaiwi1, Arane Thavaneswaran2, Nigil Haroon3, Ammepa Anton4 and Robert D. Inman5, 1Division of Rheumatology, Toronto Western Hospital, clinical and research fellow, Toronto, ON, Canada, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Toronto Western Research Institute, Toronto, ON, Canada, 4Rheumatology, University Health Network, Toronto, ON, Canada, 5Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Fatigue is one of the cardinal features of ankylosing spondylitis (AS). The clinical and laboratory correlates of fatigue in AS however are not well…
  • Abstract Number: 2606 • 2014 ACR/ARHP Annual Meeting

    How to Classify Spondyloarthritis after a Two Year Follow up? Results from the French Recent onset spondyloarthritis Cohort

    Pierre Gazeau1, Divi Cornec2, Marie Agnès Timsit1, Valerie Devauchelle3, Sandrine Jousse-Joulin1, Thierry Marhadour4, Emmanuel Nowak5, Maxime Dougados6 and Alain Saraux7, 1Rheumatology, CHU Brest, Brest, France, 2Department of rheumatology and unit of immunology, Brest Occidentale University, Brest, France, 3Rheumatology, Brest university medical school, EA 2216, Lab Ex, INSERM, IGO,UBO and CHU de la Cavale Blanche,, Brest, France, 4Rheumatology, CHU de la Cavale Blanche, Brest, France, 5CIC, CHU Brest, Brest, France, 6INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France., Paris, France, 7Rhumatologie, CHU Brest and EA 2216, UBO, Brest, France

    Background/Purpose: In early arthritis, after a two years follow up, rheumatologist diagnosis of rheumatoid arthritis agrees well with 2010 ACR/EULAR criteria (Saraux A et al.…
  • Abstract Number: 2605 • 2014 ACR/ARHP Annual Meeting

    Profiling Ankylosing Spondylitis Patients Likely to Respond to NSAID Treatment

    Mohamed Bedaiwi1, Arane Thavaneswaran2, Nigil Haroon3, Ammepa Anton4 and Robert D. Inman5, 1Division of Rheumatology, Toronto Western Hospital, clinical and research fellow, Toronto, ON, Canada, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Toronto Western Research Institute, Toronto, ON, Canada, 4Rheumatology, University Health Network, Toronto, ON, Canada, 5Department of Medicine, University of Toronto, Toronto, ON, Canada

    Background/Purpose Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease with unpredictable course of progression. Treatment of AS thus should be tailored according to disease…
  • Abstract Number: 2584 • 2014 ACR/ARHP Annual Meeting

    Smoking Is Not Associated with Response to TNF Blockers in Patients with Axial Spondyloarthritis

    Anna Dellyes1, Pierre Lafforgue1, Vincent Pradel2 and Thao Pham1, 1Rheumatology, APHM, Aix Marseille University, Marseille, France, 2Epidemiology, APHM, Aix Marseille University, Marseille, France

    Background/Purpose Smoking has been reported as associated with increase disease activity, more functional impairment, poorer quality of life and more radiographic damages in patients (pts)…
  • Abstract Number: 2583 • 2014 ACR/ARHP Annual Meeting

    Unexpected High Prevalence of Cardiac Disease in Patients with Ankylosing Spondylitis

    S.C. Heslinga1,2, Thelma C. Konings3, Irene E. Van der Horst - Bruinsma4, M.L. John4 and Mike T. Nurmohamed2, 1Internal Medicine, VU University Medical Center, Amsterdam, Netherlands, 2Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 3Cardiology, VU University Medical Center, Amsterdam, Netherlands, 4Rheumatology, VU University Medical Center, Amsterdam, Netherlands

    Background/Purpose Ankylosing spondylitis (AS) is associated with an increased cardiovascular (CV) risk that is caused by accelerated atherosclerosis as well as specific cardiac manifestations: valvular…
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