Abstracts Archive - Page 1871 of 2607 - ACR Meeting Abstracts

Abstract Number: 3261 • 2015 ACR/ARHP Annual Meeting
Examining the Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients with Breast Cancer
Dhaval Shah¹, Ram Hirpara¹, Laura K. Hummers¹, Fredrick M. Wigley², Virginia D. Steen³, Robyn T. Domsic⁴ and Ami A. Shah⁵, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheum Div/Mason F Lord, Johns Hopkins University School of Medicine, Baltimore, MD, ³Rheumatology, Georgetown University Medical Center, Washington, DC, ⁴Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁵Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Radiation oncologists are hesitant to treat scleroderma (SSc) patients with cancer due to concerns about triggering exaggerated fibrosis. In this study, we examined SSc…
Abstract Number: 3262 • 2015 ACR/ARHP Annual Meeting
The Influence of Immunosuppressive Therapy on Microangiopathy in Systemic Sclerosis As Measured with Nailfoldcapillaroscopy
Jessica Meijs¹, B. de Boer¹, Anne Schouffoer^1,2, T. W. J. Huizinga³, Hein Putter⁴ and Jeska K. de Vries-Bouwstra¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Haga Hospital, The Hague, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Medical Statitics and Bioinformatics, professor in medical statistics, Leiden, Netherlands
Background/Purpose: Microangiopathy in systemic sclerosis (SSc), as visualized by nailfold videocapillaroscopy (NVC) is a dynamic and sequential process1. In time, NVC patterns progress from early,…
Abstract Number: 3263 • 2015 ACR/ARHP Annual Meeting
The Promis-29 in Systemic Sclerosis: Associations with Clinical Characteristics in the Scleroderma Patient-Centered Intervention Network (SPIN) Cohort
Linda Kwakkenbos^1,2, Brett D. Thombs¹, Susan J. Bartlett^3,4, Marie-Eve Carrier², Marie Hudson¹, Luc Mouthon⁵, Vanessa L. Malcarne⁶, Maureen Sauvé⁷, Dinesh Khanna⁸ and SPIN investigators, ¹McGill University, Montreal, QC, Canada, ²Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada, ³Medicine , Divisions of Clinical Epidemiology, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ⁴Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD, ⁵Paris Descartes University, UPRES-EA 4058, Department of Internal Medicine, Cochin Hospital, Paris, France, ⁶SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, ⁷Scleroderma Societies of Canada and Ontario, Hamilton, QC, Canada, ⁸Division of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Systemic sclerosis (SSc) has far-reaching physical consequences and impacts health-related quality of life. The Patient-Reported Outcomes Measurement Information System (PROMIS)-29 measure includes four items…
Abstract Number: 3264 • 2015 ACR/ARHP Annual Meeting
Multiplex Serum Protein Analysis in Systemic Sclerosis Defines Potential Anti-Fibrotic Mechanisms and Markers of Response to Hyperimmune Caprine Serum
Niamh Quillinan¹, Kristina E.N. Clark¹, Deirdre McIntosh², Jeffrey Vernes² and Christopher P. Denton³, ¹Rheumatology, UCL Division of Medicine, London, United Kingdom, ²Daval International, London, United Kingdom, ³Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom
Background/Purpose: Hyperimmune caprine serum (HICS) administered by subcutaneous injection over 26 weeks has shown benefit for modified Rodnan skin score in diffuse systemic sclerosis…
Abstract Number: 3265 • 2015 ACR/ARHP Annual Meeting
Sustaining Employment with Arthritis: Can Existing Workplace Policies and Accommodations Make a Difference?
Monique A.M. Gignac^1,2, Elizabeth M. Badley³, Dorcas Beaton⁴, Vicki Kristman⁵, Cameron Mustard⁶, Peter Smith⁶ and Selahadin Ibrahim⁶, ¹Instititue for Work and Health, Toronto, ON, Canada, ²Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ³Toronto Western Research Institute, Toronto, ON, Canada, ⁴St. Michael's Hospital, Toronto, ON, Canada, ⁵Lakehead University, Toronto, ON, Canada, ⁶Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: Despite improved treatment, many individuals with inflammatory arthritis (IA) and osteoarthritis (OA) report difficulties working, reduced productivity and elevated absenteeism. Lacking is research on…
Abstract Number: 3266 • 2015 ACR/ARHP Annual Meeting
Keeping Baby Boomers in the Labour Force Longer: What Does It Mean for Workers with Arthritis?
Monique A.M. Gignac¹, Elizabeth M. Badley², Dorcas Beaton³, Vicki Kristman⁴, Cameron Mustard⁵, Peter Smith⁵ and Selahadin Ibrahim⁵, ¹Instititue for Work and Health, Toronto, ON, Canada, ²Toronto Western Research Institute, Toronto, ON, Canada, ³St. Michael's Hospital, Toronto, ON, Canada, ⁴Lakehead University, Toronto, ON, Canada, ⁵Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: There is concern that an aging workforce results in lost skills and high burden on pension programs. This has resulted in the dissolution of…
Abstract Number: 3267 • 2015 ACR/ARHP Annual Meeting
Functional Disability in Adolescents Is Predicted By Self-Report of Sleep Problems, Depressive Symptoms, Low Physical Activity and Worst Pain Intensity Levels
Kari Firestone¹, Kim Jones² and Anna Wilson³, ¹School of Nursing, Oregon Health & Science University, Portland, OR, ²Rsch & Develop/Mail Code SN OR, Oregon Health Sciences Univ, Portland, OR, ³OHSU Institute on Development and Disability, Oregon Health & Science University, Portland, OR
Background/Purpose: Pain intensity has been shown to be important in understanding pain related functional disability in adolescents. Additional factors may affect other critical outcomes including…
Abstract Number: 3268 • 2015 ACR/ARHP Annual Meeting
Foot and Ankle Characteristics Associated with Falls in People with Rheumatoid Arthritis: A Prospective Longitudinal Study
Angela Brenton-Rule¹, Nicola Dalbeth², Hylton B. Menz³, Sandra Bassett⁴ and Keith Rome⁵, ¹Podiatry, AUT University, Auckland, New Zealand, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³Musculoskeletal Research Centre, La Trobe University, Bundoora, VIC, Australia, ⁴AUT University, Auckland, New Zealand, ⁵Health & Research Rehabilitation Centre, AUT University, Auckland, AR, New Zealand
Background/Purpose: People with rheumatoid arthritis (RA) have an increased risk of falls. The consequences of falls include loss of confidence and independence, injury and death.…
Abstract Number: 3269 • 2015 ACR/ARHP Annual Meeting
Trends in Prevalence of Knee Pain Among US Adults, National Health Interview Survey, 2002-2010
Jennifer M. Hootman¹, Charles G. Helmick² and Yvonne M. Golightly³, ¹Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ²Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ³Epidemiology, University of North Carolina, Chapel Hill, NC
Trends in prevalence of knee pain among US adults, National Health Interview Survey, 2002-2010 Background/Purpose : Aging of the population as well as the obesity…
Abstract Number: 3270 • 2015 ACR/ARHP Annual Meeting
Correction of Limb Length Inequality in Adults with Knee or Hip Symptoms: A Pilot Study
Yvonne M. Golightly¹, Michael T. Gross², Amanda Nelson³, Leigh F. Callahan⁴ and Joanne M. Jordan⁴, ¹Epidemiology, University of North Carolina, Chapel Hill, NC, ²University of North Carolina, Chapel Hill, NC, ³Division of Rheumatology, Allergy, and Immunology and Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Limb length inequality (LLI; paired lower extremities of unequal length) is associated with knee and hip osteoarthritis (OA) and symptoms consistent with OA (pain,…
Abstract Number: 2 • 2015 ACR/ARHP Annual Meeting
The Neutrophil Protein S100A12 Has Stronger Associations with a Comprehensive Ultrasound Score of Synovitis Than Vascular Endothelial Growth Factor in a Longitudinal Study of Rheumatoid Arthritis Patients
Hilde Haugedal Nordal^1,2 and Hilde Berner Hammer³, ¹Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, ²Department of Rheumatology, Haukeland University Hospital, Bergen, Norway, ³Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: S100A12, a neutrophil protein, has proinflammatory effects on immune cells and can activate endothelial cells. The mechanism of action suggests vascular endothelial growth factor…
Abstract Number: 8 • 2015 ACR/ARHP Annual Meeting
Bay 11-7085 Induces Glucocorticoid Receptor Activation and Autophagy to Initiate Human Synovial Fibroblast Cell Death
Biserka Relic¹, Edith Charlier², Céline Deroyer¹, Olivier Malaise¹, Sophie Neuville¹, Aline Desoroux¹, Philippe Gillet³, Michel G. Malaise¹ and Dominique de Seny¹, ¹Department of Rheumatology- GIGA Research - Arthropôle - University of Liège - CHU Liège, Liège, Belgium, ²Department of Rheumatology, Department of Rheumatology- GIGA Research - Arthropôle - University of Liège - CHU Liège, Liège, Belgium, ³Orthopaedic Surgery Department-University of Liège-CHU de Liège, Liège, Belgium
Background/Purpose: BAY 11-7085 is an inhibitor of IκBα phosphorylation that leads to NF-κB inactivation and downregulation of inflammation in mouse model of asthma, in articular…
Abstract Number: 9 • 2015 ACR/ARHP Annual Meeting
Serum Visfatin Levels in Patients with Axial Spondyloarthitis and Early Rheumatoid Arthritis: Relation to Inflammation and Bone Changes
Hana Hulejova¹, Klára Prajzlerová², Olga Krystufkova², Krystýna Grobelná², Maria Filkova², Herman F Mann³, Karel Pavelka⁴, Jiri Vencovsky³ and Ladislav Senolt⁵, ¹Institute of Rheumatology and Department of Rheumatology, Prague, Czech Republic, ²Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ³Institute of Rheumatology, Prague, Czech Republic, ⁴Charles University, Prague, Czech Republic, ⁵Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Visfatin may represent a novel biomarker of disease severity. Serum visfatin levels are elevated in patients with early rheumatoid arthritis (ERA) and axial spondyloarthritis…
Abstract Number: 46 • 2015 ACR/ARHP Annual Meeting
Feasibility Study of Smartphone Data Collection for Cloudy with a Chance of Pain: Sustained Engagement for Daily Self-Reporting of Disease Severity in Rheumatoid Arthritis over Two Months
Samuel Reade¹, Jamie C Sergeant^2,3, Matthew Sperrin⁴, David M. Schultz⁵, Karen Spencer⁶, Caroline Sanders⁶ and William G Dixon⁷, ¹The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, ⁴Institute of Population Health, Health e-Research Centre, The University of Manchester, Manchester, United Kingdom, ⁵Faculty of Engineering and Physical Sciences, School of Earth, Atmospheric and Environmental Sciences, The University of Manchester, Manchester, United Kingdom, ⁶Institute of Population Health, Centre for Primary Care, The University of Manchester, Manchester, United Kingdom, ⁷Manchester Academic Health Sciences Centre, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Previous research has attempted to study the association between weather and joint pain. Inconclusive results may be due, in part, to infrequent measures of…
Abstract Number: 1 • 2015 ACR/ARHP Annual Meeting
The Integrin Very Late Antigen-4 Plays a Key Role in the Recruitment of B Cells at the Inflammatory Foci
Estefanía Armas-González¹, Ana Díaz-Martín², María Jesús Domínguez-Luis³, María Teresa Arce-Franco² and Federico Díaz-González⁴, ¹Universidad de La Laguna, Pharmacology Department, Tenerife, Spain, ²Hospital Universitario de Canarias, Rheumatology Service, Tenerife, Spain, ³CIBICAN, Center of Biomedical Research of the Canary Islands, University of La Laguna, Tenerife, Spain, ⁴Investigation Unit, Sociedad Española de Reumatológía, Madrid, Spain
Background/Purpose: Experimental data suggest that B cells must migrate and accumulate into the synovial membrane to exert their pathogenic role in rheumatoid arthritis (RA). Leukocyte…

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