Abstracts Archive - Page 187 of 2425 - ACR Meeting Abstracts

Abstract Number: 0312 • ACR Convergence 2023
Frontal Lobe Activation and Gait Alterations During Single- and Dual-task Walking in People with Knee Osteoarthritis: A Functional Near-infrared Spectroscopy Study
Soyoung Lee, Meryem Yücel, Claudio Ferre, Baekdong Cha, Ehyun Kim and Deepak Kumar, Boston University, Boston, MA
Background/Purpose: Altered gait patterns, including high variability or muscular co-contraction, can increase fall risk and worsen disease progression in people with knee osteoarthritis (OA). However,…
Abstract Number: 0317 • ACR Convergence 2023
Long-term Effectiveness of a Lifestyle Program for Osteoarthritis: One-year Follow-up of the “Plants for Joints” Randomized Clinical Trial
Carlijn Wagenaar¹, Wendy Walrabenstein¹, Marike Van der Leeden², Martijn Gerritsen², Jos W.R. Twisk¹, Martin van der Esch², Henriët van Middendorp³, Peter Weijs⁴ and Dirkjan van Schaardenburg⁵, ¹Amsterdam University Medical Centers, Amsterdam, Netherlands, ²Reade Rheumatology Center, Amsterdam, Netherlands, ³Leiden University, Leiden, Netherlands, ⁴Amsterdam University of Applied Sciences, Amsterdam, Netherlands, ⁵Reade, Amsterdam, Netherlands
Background/Purpose: The 16-week Plants for Joints (PFJ) multidisciplinary lifestyle program, based on a whole-food plant-based diet, physical activity, and stress management, significantly reduced The Western…
Abstract Number: 0322 • ACR Convergence 2023
Validation of NICE Criteria for the Diagnosis of Knee Osteoarthritis
Lauren King¹, Ian Stanaitis², Vivian Hung², Sahil Koppikar³, Esther Waugh⁴, Lorraine Lipscombe³ and Gillian Hawker³, ¹Women's College Hospital & St. Michael's Hospital & University of Toronto, Toronto, ON, Canada, ²Women's College Hospital, Toronto, ON, Canada, ³Women's College Hospital & University of Toronto, Toronto, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada
Background/Purpose: The NICE guideline on osteoarthritis (OA) recommends that adults aged ≥45 should be diagnosed with OA clinically, without investigations, if they have activity-related joint…
Abstract Number: 0319 • ACR Convergence 2023
Knee Flexion Contracture Was Associated with Articular Cartilage Loss in the Central Region but Cartilage Preservation in the Posterior Region of the Tibia: Data from the Osteoarthritis Initiative
Mark Campbell¹, Odette Laneuville² and Guy Trudel³, ¹Elisabeth Bruyere Hospital, Ottawa, ON, Canada, ²University of Ottawa, Ottawa, ON, Canada, ³Ottawa Hospital Research Institute, Ottawa, ON, Canada
Background/Purpose: A knee flexion contracture (FC), present in ~⅓ of patients with knee OA1, is the inability to fully extend the knee2, 3. Having a…
Abstract Number: 0320 • ACR Convergence 2023
Feasibility and Acceptability of Geniculate Artery Embolization for the Treatment of Painful Knee Osteoarthritis
Amaya Smole¹, Benjamin Swett¹, Alison Zhao¹, Yvonne Shea¹, Sarah Gottesman¹, Dongmei Sun¹, Geoffrey Westrich¹, Michael Alexiades¹, Alejandro Gonzalez Della Valle¹, Sirish Kishore² and Lisa Mandl³, ¹Hospital for Special Surgery, New York, NY, ²Stanford Medicine, Stanford, CA, ³Hospital for Special Surgery, Weill Cornell Medicine, New York, NY
Background/Purpose: There are limited non-surgical options for patients with severe pain due to knee osteoarthritis (KOA).Using geniculate artery embolization (GAE) to infarct hypervascular synovium, a…
Abstract Number: 0323 • ACR Convergence 2023
A Randomized, Double-blind, Placebo-controlled, Repeat Injection, 52-Week Study to Evaluate the Efficacy and Safety of an Intra-articular Injection (IAI) of CNTX-4975-05 (CNTX) in Subjects with Chronic, Moderate-to-severe Osteoarthritis Knee Pain (MSOAKP) – Study 304
James Connolly, James N Campbell, Randall Stevens and Colleen Newman, Centrexion Therapeutics Corporation, Boston, MA
Background/Purpose: 30+ million US adults have OAKP. After years of using NSAIDs, analgesics, surgery and IAI, many patients remain with MSOAKP. CNTX is a 1…
Abstract Number: 0318 • ACR Convergence 2023
The Association of CT-Detected Intra-Articular Mineralization with MRI-Detected Effusion-Synovitis and Hoffa’s Synovitis in Knee OA: The Multicenter Osteoarthritis Study
Jean Liew¹, Gabriela Rabasa¹, Mohamed Jarraya², Ali Guermazi¹, David Felson¹, Beth Lewis³, John Lynch⁴, Michael Nevitt⁴, James Torner⁵ and Tuhina Neogi⁶, ¹Boston University, Boston, MA, ²Massachusetts General Hospital, Boston, MA, ³University of Alabama at Birimingham, Birmingham, AL, ⁴University of California San Francisco, San Francisco, CA, ⁵University of Iowa, Iowa City, IA, ⁶Boston University School of Medicine, Boston, MA
Background/Purpose: Intra-articular (IA) deposition of calcium crystals (chondrocalcinosis), is common in knee OA. While calcium crystals can cause inflammatory arthritis, their contribution to joint inflammation…
Abstract Number: 0327 • ACR Convergence 2023
Self-management Strategies and Self-efficacy in Patients Living with Inflammatory Arthritis: Findings from a Quality Improvement Project in a Tertiary Centre
Saadia Sasha Ali¹, Karafotias Ioasaf², Bechman Katie³, Andrew Rutherford⁴, Sophia Steer³ and Elena Nikiphorou³, ¹King's College Hospital, Epsom, United Kingdom, ²King's College Hospital, London, United Kingdom, ³King's College London, London, United Kingdom, ⁴King's College Hospital, London, United Kingdom
Background/Purpose: The 2021 EULAR guidelines on self-management have made recommendations (rec) to aid with the implementation of self-management strategies in inflammatory arthritis (IA) (1). Their…
Abstract Number: 0330 • ACR Convergence 2023
Patient-Reported Experiences and Comorbidities in Patients with IgG4-Related Disease with and Without Pancreatic Involvement
Liam Harvey¹, Guy Katz², Yasmin Hernandez-Barco², Ana Fernandes², Aubree McMahon², Grace McMahon², Isha Jha², Zachary Wallace³, Cory Perugino² and John Stone⁴, ¹Frank H. Netter School of Medicine at Quinnipiac University, New Haven, CT, ²Massachusetts General Hospital, Boston, MA, ³Massachusetts General Hospital, Newton, MA, ⁴Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Concord, MA
Background/Purpose: IgG4-Related Disease (IgG4-RD) is a systemic immune-mediated disease that commonly involves the pancreas in the form of autoimmune pancreatitis (AIP). Despite being one of…
Abstract Number: 0284 • ACR Convergence 2023
Phenotyping Calcinosis: A Rare Manifestation of Rare Diseases
Michele Diomedi¹, Federico Fattorini¹, Simone Barsotti², Elenia Laurino¹, Chiara Cardelli¹, Linda Carli¹ and Marta Mosca¹, ¹Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, ²Internal Medicine, Ospedale di Livorno, Pisa, Italy
Background/Purpose: Idiopathic inflammatory myopathies (IIMs) are rare systemic autoimmune disorders, with a pleiotropic clinical picture, specifically characterized from the inflammatory involvement of striate muscles. Calcinosis…
Abstract Number: 0280 • ACR Convergence 2023
Immunosuppression in the Treatment of Susac Syndrome: A Retrospective Evaluation of the Largest Cohort of Susac Syndrome
Adam Brown¹, Robert Rennebohm², Ghulam Abbas Kharal², Devon Conway², Sunil Srivastava³, Sumit Sharma², Careen Lowder², Leonard Calabrese⁴ and Rula Hajj-Ali², ¹Cleveland Clinic Department of Rheumatic and Immunologic Diseases, Cleveland, OH, ²Cleveland Clinic, Cleveland, OH, ³Cincinnati Eye Institute, Cincinnati, OH, ⁴Cleveland Clinic / Department of Rheumatic and Immunologic Diseases, Cleveland, OH
Background/Purpose: Susac Syndrome is a rare autoimmune condition causing microvascular occlusions in the brain, retina and inner ear leading to the characteristic triad of encephalopathy,…
Abstract Number: 0291 • ACR Convergence 2023
Myopathy Related to Small-to-medium-sized Vessel Vasculitis: Immunopathological Characteristics
Shun Nomura, Yasuhiro Shimojima, Takanori Ichikawa, Daigo Miyazaki, Dai Kishida and Yoshiki Sekijima, Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan
Background/Purpose: Muscular involvement develops as the initial manifestation of small-sized vessel vasculitis (SV) and medium-sized vessel vasculitis (MV).The musculoskeletal lesion has been found as a…
Abstract Number: 0301 • ACR Convergence 2023
Inflammatory Myopathies and Their Relationship with Cancer in a Colombian Cohort
Bolaños Juan D.¹, Rivera-Londoño Robert¹, Ivana Nieto-Aristizabal¹, Karol Enriquez², Santiago Zura², Alex Echeverri¹, Andrés Hormaza-Jaramillo¹ and David Aguirre-Valencia¹, ¹Fundación Valle del Lili, Cali, Colombia, ²Universidad ICESI, Cali, Colombia
Background/Purpose: Inflammatory myopathies (IM) constitute a heterogeneous group of autoimmune muscle diseases. These can occur in isolation, associated with other autoimmune disorders, or as a…
Abstract Number: 0304 • ACR Convergence 2023
Incidence of Disease Flares Following COVID-19 Vaccination in a Diverse Idiopathic Inflammatory Myopathy Cohort
Hillary Weisleder¹, Ana Valle¹, Xianhong Xie² and Shereen Mahmood³, ¹Montefiore Medical Center, Bronx, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Albert Einstein College of Medicine / Montefiore Medical Center, New York, NY
Background/Purpose: Autoimmune activation in the setting of vaccination against coronavirus disease 2019 (COVID-19) is a well-documented phenomenon in the medical literature. For patients with idiopathic…
Abstract Number: 0309 • ACR Convergence 2023
Efficacy, Safety, Pharmacokinetics and Immunogenicity of Repeated Dosing of GSK3858279 in Patients with Knee Osteoarthritis: A Phase I, Randomized, Double-Blind, Placebo-Controlled Study
Jagtar Singh Nijjar¹, Kathy Abbott-Banner², Riju Ray³, Sam Munoz Vicente¹, Jane H. Bentley¹, Catherine Muya¹, Sarah Siederer¹, Eirini Panoilia¹, Damon Bass⁴, Disala Fernando⁵ and Edward C. Emery¹, ¹GlaxoSmithKline, Stevenage, United Kingdom, ²GlaxoSmithKline, Brentford, United Kingdom, ³GSK Research, Triangle Park, ⁴GlaxoSmithKline, Upper Providence, RI, ⁵GlaxoSmithKline, Cambridge, United Kingdom
Background/Purpose: Chronic pain is an unmet need in osteoarthritis (OA) as current therapies have limited analgesia and side effects. The chemokine CCL17 mediates inflammatory pain…

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