Abstracts Archive - Page 1856 of 2607 - ACR Meeting Abstracts

Abstract Number: 3035 • 2015 ACR/ARHP Annual Meeting
HLA B51 and Possible Associated Autoimmune Disorders Other Than Behcets Disease: A Retrospective Cohort Study
Luis Salayandia¹, Wilmer Sibbitt Jr.¹, Arthur Bankhurst², Roderick Fields³, Gladys Cook⁴, Konstantin Konstantinov⁵ and Suzanne Emil¹, ¹Rheumatology, University of New Mexico, Albuquerque, NM, ²Rheum/ MSC 105550, University of NM Med Ctr, Albuquerque, NM, ³Rheumatology, University of New Mexico, Albquerque, NM, ⁴Rheumatology, UNM, Albuquerque, NM, ⁵1 University Of New Mexico, University of New Mexico, Albuquerque, NM
Background/Purpose: The diagnostic utility of HLA B51 in association with Behcet’s disease has been clearly identified; however the correlation of HLA B51 with other autoimmune…
Abstract Number: 3036 • 2015 ACR/ARHP Annual Meeting
The Association Between Behcet’s Disease, Myelodysplastic Syndrome and Trisomy 8
Won-Seok Lee¹, Yun Jung Choi², Myong-Joo Hong³, Chang-Hoon Lee⁴, Myeung Su Lee⁵, Young Sun Suh⁶, Sang-Il Lee⁷, Yong Gon Cho⁸ and Wan-Hee Yoo⁹, ¹Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, jeonju, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, JeonJu, South Korea, ³Internal Medicine, Presbyterian Medical center, Jeonju, South Korea, ⁴Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ⁵Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ⁸Department of Laboratory medicine, Chonbuk National University Medical School and Hospital, Jeonju, South Korea, ⁹Division of Rhuematology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, Jeonju, South Korea
Background/Purpose: Behcet’s disease (BD) is a systemic vasculitis, whereas myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematologic disorders characterized by ineffective hematopoiesis. Some…
Abstract Number: 3037 • 2015 ACR/ARHP Annual Meeting
Serum Anti-Lysozyme Is Associated with Disease Activity of Behcet’s Disease
Jin Su Park¹, Mi-il Kang², You Jung Ha³, Yong-Beom Park⁴, Soo-Kon Lee⁵ and Sang-Won Lee⁶, ¹Department of Internal Medicine, NHIS Ilsan Hospital, Goyang-si Gyeounggi-do, South Korea, ²Department of Internal Medicine, Dankook University Hospital, Cheonan-si Chungcheongnam-do, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, South Korea, ⁴Yonsei University College of Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul, South Korea, ⁵Internal Medicine, Yonsei Univ College of Med, Seoul, South Korea, ⁶Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
Background/Purpose: To investigate the association between autoantibodies against non- myeloperoxidase (MPO) neutrophil granule antigens and activity of Behcet’s disease (BD). Methods: We consecutively enrolled 51…
Abstract Number: 3038 • 2015 ACR/ARHP Annual Meeting
Serum CXCL8, 10 and 12 Are Increased in Patients with Behcet’s Disease and CXCL10 Levels Are Correlated with Number of Erythema Nodosum
Sang Jin Lee^1,2, Hyun Jung Yoo³, Hyun Mi Kwon⁴, Jin Young Moon⁴, Jin Kyun Park⁵, Eun Young Lee⁵, Eun Bong Lee⁴ and Yeong Wook Song⁵, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ²Department of Molecular Medicine and Biopharmaceutical Sciences, BK21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, South Korea, ³Department of Molecular Medicine and Biopharmaceutical Sciences, BK 21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Parmarcy, Seoul National University, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Seoul National University, Seoul, South Korea
Background/Purpose: Chemokines are multifunctional mediators that control leukocyte recruitment into the inflammatory sites and enhance immune responses. It remains to be investigated which chemokines are…
Abstract Number: 3039 • 2015 ACR/ARHP Annual Meeting
Possible Contribution of HLA-A0207, B5201 and IL-23 Receptor Polymorphism in Ocular Behçet Disease
Toshikatsu Kaburaki¹, Shinji Harihara², Rie Tanaka³, Hiromasa Sawamura⁴, Ai Nishi⁴, Atsushi Hatamochi⁵, Jun Shimizu⁶, Masumi Takeuchi⁷, Shoji Kuwata⁸, Hidetoshi Kawashima⁹ and Fujio Takeuchi¹⁰, ¹Ophthalmology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, ²Division of Anthropology, Department of Biological Science, The University of Tokyo Graduate School of Science, Tokyo, Japan, ³Department of Ophtalmology, The University of Tokyo Graduate School of Medicine,, Tokyo, Japan, ⁴Department of Ophtalmology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, ⁵Department of Dermatology, Dokkyo Medical University, Tochigi, Japan, ⁶Department of Neurology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, ⁷Teikyo University Support Center for Women Physicians and Researchers, Teikyo University School of Medicine, Tokyo, Japan, ⁸Third Department of Internal Medicine, Teikyo University Chiba Medical Center, Teikyo University School of Medicine, Chiba, Japan, ⁹Department of Ophthalmology, Jichi Medical University, Tochigi, Japan, ¹⁰Department of Allergy and Rheumatology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
Background/Purpose: Behçet's disease (BD) is known to be associated with HLA-B*51:01 and HLA- A*26:01 in many different ethnic groups. Recently, HLA-A*02:07, IL-10 and IL23R-IL12RB polymorphisms…
Abstract Number: 3040 • 2015 ACR/ARHP Annual Meeting
Predictive Factors of Long-Term Clinical Outcome in Patients with Ocular Involvement Secondary to Behcet’s Syndrome
Rosaria Talarico¹, Michele Figus², Anna d'Ascanio¹, Rossella Neri¹, Chiara Baldini¹, Chiara Tani³ and Marta Mosca¹, ¹Rheumatology Unit, University of Pisa, Italy, Pisa, Italy, ²Department of Surgical, Medical, Molecular Pathology and Emergency, University of Pisa, Pisa, Italy, ³University of Pisa, Pisa, Italy
Background/Purpose: Behçet's syndrome (BS) is a multisystemic, chronic relapsing inflammatory disease classified among the vasculitis. Eye involvement represent one of the most serious manifestation of…
Abstract Number: 3041 • 2015 ACR/ARHP Annual Meeting
Long Term Biological Therapy in Uveitis Refractory Due to Behçet’s Disease. Multicenter Study of 165 Patients.
Montserrat Santos-Gómez¹, Vanesa Calvo-Río¹, Ricardo Blanco¹, Emma Beltran², Juan Sánchez Bursón Sr.³, Marina Mesquida⁴, Alfredo Adan⁴, M. Victoria Hernández⁵, F.Javier López-Longo⁶, Marisa Hernandez Grafella⁷, Elia Valls Pascual⁸, Lucía Martinez-Costa⁹, Agusti Sellas-Fernandez¹⁰, Miguel Cordero¹¹, Manuel Díaz-Llopis¹², Roberto Gallego¹³, Jose L. García Serrano¹⁴, JL Callejas Rubio¹⁵, Norberto Ortego-Centeno¹⁶, Jose M Herreras¹⁷, Alejandro Fonollosa¹⁸, Angel M. Garcia-Aparicio¹⁹, Olga Maiz Alonso²⁰, Ana Blanco²¹, Ignacio Torre²², Cruz Fernández- Espartero²³, Vega Jovani²⁴, Diana Peiteado²⁵, David Diaz Valle²⁶, Esperanza Pato²⁶, Juan Cruz²⁷, Carlos Férnandez Cid²⁸, Elena Aurrecoechea²⁹, Miriam García-Arias³⁰, Miguel Angel Caracuel-Ruiz³¹, Carlos Alberto Montilla Morales³², Antonio Atanes-Sandoval³³, Félix Francisco³⁴, Santos Insua³⁵, Senen González-Suárez³⁶, Amalia Sánchez-Andrade³⁷, Fernando Gamero³⁸, Luis Francisco Linares³⁹, Fredeswinda Romero⁴⁰, A. Javier García-González⁴¹, Raquel Almodóvar González⁴², Enrique Minguez⁴³, Carmen Carrasco Cubero⁴⁴, Alejandro Olivé⁴⁵, Julio Vázquez⁴⁶, Oscar Ruiz Moreno⁴⁷, Fernando Jiménez-Zorzo⁴⁸, Javier Manero⁴⁸, Santiago MuÑoz Fernandez⁴⁹, Cristina Fernández-Carballido⁵⁰, Esteban Rubio Romero⁵¹, Fred Antón Pagés⁵², Javier Toyos-Saenz de Miera⁵³, Myriam Gandía⁵⁴, Carmen Gonzalez-Vela⁵⁵, Enrique Raya⁵⁶, Natalia Palmou¹, Leyre Riancho-Zarrabeitia¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Rheumatology, Hospital General Universitario de Valencia, Valencia, Spain, ³Rheumatology, Hospital de Valme., Sevilla, Spain, ⁴Ophthalmology, Hospital Clinic, Barcelona, Spain, ⁵Arthritis Unit, Rheumatology, Hospital Clinic, Barcelona, Spain, ⁶Hospital Gregorio Marañón, Madrid, Spain, ⁷Ophthalmology., Hospital General Universitario de Valencia, Valencia, Spain, ⁸Rheumatology, Hospital Universitario Dr Peset, Valencia, Spain, ⁹Ophthalmology, Hospital Universitario Dr Peset, Valencia, Spain, ¹⁰Rheumatology, Hospital Universitario Valle Hebron, Barcelona, Spain, ¹¹Ophthalmology, Hospital de León, León, Spain, ¹²Hospital Universitario La Fe, Valencia, Spain, ¹³Ophthalmology, Hospital Universitario La Fe, Valencia, Spain, ¹⁴Ophthalmology, Hospital Universitario San Cecilio, Granada, Spain, ¹⁵Hospital Universitario San Cecilio, Granada, Spain, ¹⁶Systemic Autoimmune Diseases Unit, Hospital Universitario San Cecilio, Granada, Spain, ¹⁷Ophthalmology, Hospital Universitario, IOBA, Valladolid, Spain, ¹⁸Ophtalmology, Hospital de Cruces, Bilbao, Spain, ¹⁹Rheumatology, Hospital Virgen de la Salud, Toledo, Spain, ²⁰Rheumatology, Donostia University Hospital, Donostia, Spain, ²¹Ophthalmology, Donostia University Hospital, Donostia, Spain, ²²Rheumatology, Hospital de Basurto, Bilbao, Spain, ²³Rheumatology, Hospital La Zarzuela, Madrid, Spain, ²⁴Rheumatology, Hospital General de Alicante, Alicante, Spain, ²⁵Rheumatology, Hospital La Paz, Madrid, Spain, ²⁶Hospital Clínico San Carlos, Madrid, Spain, ²⁷Rheumatology, Hospital de Pontevedra, Pontevedra, Spain, ²⁸Ophthalmology, Hospital de Pontevedra, Pontevedra, Spain, ²⁹Rheumatology, Hospital de Sierrallana, Torrelavega, Spain, ³⁰Rheumatology, Hospital La Princesa, Madrid, Spain, ³¹Plaza Cruz Roja, 1, Hospital Reina Sofia, Córdoba, Spain, ³²Rheumatology, Hospital Universitario de Salamanca, Salamanca, Spain, ³³Rheumatology, Complejo Hospitalario Universitario de La Coruña, La Coruña, Spain, ³⁴Rheumatology, Hospital Doctor Negrín, Las Palmas de Gran Canaria, Spain, ³⁵Rheumatology, Hospital Universitario Santiago de Compostela, La Coruña, Spain, ³⁶Rheumatology, Hospital de Cabueñes, Gijón, Spain, ³⁷Hospital Lucus Augusti, Lugo, Spain, ³⁸Rheumatology, Hospital San Pedro Alcántara, Cáceres, Spain, ³⁹Rheumatology, Hospital Virgen de la Arrixaca, Murcia, Spain, ⁴⁰Section for Autoimmune Diseases, Rheumatology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, ⁴¹Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, ⁴²Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, ⁴³Ophthalmology., Hospital Clínico de Zaragoza, Zaragoza, Spain, ⁴⁴Rheumatology, Hospital de Mérida, Mérida, Spain, ⁴⁵Hospital Germans Trias i Pujol, Badalona, Spain, ⁴⁶Rheumatology., Hospital de Ferrol, La Coruña, Spain, ⁴⁷Ophthalmology and Rheumatology., Hospital Miguel Servet, Zaragoza, Spain, ⁴⁸Ophthalmology and Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, ⁴⁹Rheumatology, Hospital Infanta Sofía, Madrid, Spain, ⁵⁰Rheumatology, Hospital General Universitario de Elda, Elda (Alicante), Spain, ⁵¹Rheumatology Department,, Hospital Universitario Virgen del Rocío, Sevilla, Spain, ⁵²Rheumatology, Hospital de Palencia, Palencia, Spain, ⁵³Rheumatology, Hospital Virgen de la Macarena, Seville, Spain, ⁵⁴Department of Autoimmune Diseases, IDIBAPS, Hospital Clínic, Barcelona, Spain, ⁵⁵Pathology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁵⁶Rheumatology, Hospital Universitario San Cecilio, Granada, Spain
Background/Purpose: Conventional management of uveitis due to Behçet’s disease (UBD) consists on conventional immunosuppressive drugs. However, UBD is often refractory requiring more intensive therapy.Our aim was…
Abstract Number: 3042 • 2015 ACR/ARHP Annual Meeting
Tocilizumab in Refractory Uveitis Associated with Behçet’s Disease. Multicenter Study of 7 Patients.
Montserrat Santos-Gómez¹, Vanesa Calvo-Río¹, Ricardo Blanco¹, Emma Beltran², Antonio Atanes-Sandoval³, Enar Pons⁴, Javier Loricera¹, Carmen Gonzalez-Vela⁵, Leyre Riancho-Zarrabeitia¹, Natalia Palmou¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Rheumatology, Hospital General Universitario de Valencia, Valencia, Spain, ³Rheumatology, Complejo Hospitalario Universitario de La Coruña, La Coruña, Spain, ⁴Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁵Pathology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain
Background/Purpose: Treatment recommended in severe and/or refractory uveitis of Behçet disease is anti-TNF-α therapy, usually infliximab (IFX) or adalimumab (ADA) (Levy-Clarke et al Ophthalmology 2014;121:785-796).…
Abstract Number: 3043 • 2015 ACR/ARHP Annual Meeting
IL-17 Expression By Lymphocytes Is Higher in Behcet’s Disease Compared to Takayasu Arteritis
Ali Ugur Unal¹, Rabia Deniz², Aysin Tulunay Virlan³, Filiz Ture Ozdemir³, Imren Aydin Tatli³, Gulsen Ozen¹, Fatma Alibaz-Oner⁴, Gonca Mumcu⁵, Tulin Ergun⁶ and Haner Direskeneli¹, ¹Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ²Marmara University Faculty of Medicine, Istanbul, Turkey, ³Department of Immunology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Department Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁵Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, ⁶Dermatology, Marmara University Faculty of Medicine, Dermatology, Istanbul, Turkey
Background/Purpose: Interleukin-17 (IL-17) has been associated with the pathogenesis of various inflammatory diseases. The aim of our study was to investigate the expression of Th17-related…
Abstract Number: 3044 • 2015 ACR/ARHP Annual Meeting
Microparticles (MPs) Derived from Cell Plasma Membranes Are Increased in Behcet’s Syndrome (BS) and a Low Ratio of Tissue Factor Pathway Inhibitor Positive Mps to Tissue Factor Positive Mps (TFPI/TF) Is Associated with Thrombosis
Emon Khan¹, Nicola Ambrose¹, Miles Stanford², Michael A. Laffan³ and Dorian O. Haskard⁴, ¹Department of Vascular Sciences, National Heart and Lung Institute, Imperial College, London, United Kingdom, ²Ophthalmology, Guy's and St. Thomas' Hospital, London, United Kingdom, ³Department of Haemostasis and Thrombosis, Imperial College, London, United Kingdom, ⁴Rheumatology, Imperial College, London, United Kingdom
Background/Purpose: Thrombosis occurs in around 20% of Behçet's Syndrome (BS) patients and causes substantial morbidity. There is a clear need for better biomarkers of thrombotic…
Abstract Number: 3045 • 2015 ACR/ARHP Annual Meeting
Anti-Alpha-Enolase Antibodies in Behçet’s Disease: A Marker of Articular Disease Activity?
Leandro L. Prado, Celio R. Gonçalves, Vilma S. T. Viana, Eloisa Bonfá and Carla G.S. Saad, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Diagnosis of Behçet´s disease (BD) is challenging because is based solely on clinical features. Articular involvement in this disease may mimic other diagnosis such…
Abstract Number: 3046 • 2015 ACR/ARHP Annual Meeting
Venous Disease-Specific Quality-of-Life Is Impaired in Patients with Vascular Behcet’s Disease
Fatma Alibaz-Oner¹, Belgin Aldag², Mustafa Aldag³, Ali Ugur Unal⁴, Tayfur Toptas⁵, Tülin Ergun⁶ and Haner Direskeneli⁴, ¹Department Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ²Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ³Dr.Siyami Ersek Cardiovascular Surgery Hospital,, Istanbul, Turkey, ⁴Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁵Hematology, Marmara University, Istanbul, Turkey, ⁶Dermatology, Marmara University Faculty of Medicine, Dermatology, Istanbul, Turkey
Background/Purpose: Vascular involvement is seen in up to 40% of the patients with Behcet's disease (BD), with lower extremity deep vein thrombosis (DVT) as the most…
Abstract Number: 3047 • 2015 ACR/ARHP Annual Meeting
Association Between Red Blood Cell Distribution Width and Disease Activity in Behcet’s Disease
Byung-Woo Yoo, Jason Jungsik Song, Sang-Won Lee, Yong-Beom Park, Soo-Kon Lee and Sung Soo Ahn, Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
Background/Purpose: Behcet's disease (BD) is a chronic systemic inflammatory disorder characterized by recurrent oral aphtae and other systemic involvement. Red blood cell distribution width (RDW)…
Abstract Number: 3048 • 2015 ACR/ARHP Annual Meeting
Work Disability over Time in Behcet’s Syndrome
Gulen Hatemi¹, Koray Tascilar², Yesim Ozguler³, Serdal Ugurlu⁴ and Vedat Hamuryudan¹, ¹Rheumatology, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey, ²Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey, ³Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ⁴Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
Background/Purpose: Behcet’s syndrome (BS) is most active during young adulthood and may cause severe disability. We had previously observed a high frequency of work disability…
Abstract Number: 3049 • 2015 ACR/ARHP Annual Meeting
Cognitive Dysfunction in Chronic Progressive Neuro-Behçet’s Disease: Comparative Study of the Brainstem and Hippocampus Region Using Brain Magnetic Resonance Imaging
Hirotoshi Kikuchi¹, Kurumi Asako¹, Maki Takayama¹, Shoko Iga¹, Yoshitaka Kimura¹, Hajime Kono¹ and Shunsei Hirohata², ¹Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, ²Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan
Background/Purpose: Central nervous system involvement is one of the most serious complications in Behçet's disease (BD). This condition is referred to as neuro-Behçet's disease (NB)…

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