Abstracts Archive - Page 1851 of 2607 - ACR Meeting Abstracts

Abstract Number: 2959 • 2015 ACR/ARHP Annual Meeting
Patterns of Vascular Brain Injury in Systemic Lupus Erythematosus Patients with Ischemic Stroke: Impact on Neuropsychological, Neurobehavioral and Physical Function Outcome
Jamal A. Mikdashi¹, Marcia Wozniak², Umran Ashraf³ and William Regenold⁴, ¹Div of Rheumatology, Univ of Maryland Schl of Med, Baltimore, MD, ²Neurology, University of Maryland School of Medicine, Baltimore, MD, ³Radiology, University fo Maryland, Baltimore, MD, ⁴Psychiatry, Univeristy of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Ischemic strokes in Systemic lupus erythematosus (SLE) patients contribute to increased morbidity and mortality. Little is known however, about the patterns of ischemic brain…
Abstract Number: 2960 • 2015 ACR/ARHP Annual Meeting
Sodium Thiosulfate in Calcinosis
Eliza Pelrine¹, Jessica K. Gordon², Murray Baron³ and Robert F. Spiera², ¹Hospital for Special Surgery, New York, NY, ²Rheumatology, Hospital for Special Surgery, New York, NY, ³Rheumatology, McGill University, Jewish General Hospital, Montreal, QC, Canada
Background/Purpose: Calcinosis occurs in ~25% of patients with Systemic Sclerosis (SSc) and causes pain, morbidity, and decreased quality of life. The treatment of calcinosis is…
Abstract Number: 2961 • 2015 ACR/ARHP Annual Meeting
Reliability and Validity of the Total Joint Count and Swollen Joint Count in Early Diffuse Systemic Sclerosis
Jessica K. Gordon¹, Veronica J. Berrocal², Gandikota Girish³, Meng Zhang⁴, Chris Hatzis¹, Shervin Assassi⁵, Elana J. Bernstein⁶, Robyn T. Domsic⁷, Faye N. Hant⁸, Monique E. Hinchcliff⁹, Elena Schiopu¹⁰, Virginia D. Steen¹¹, Tracy M. Frech¹² and Dinesh Khanna¹³, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Div of Rheumatology, University of Michigan, Ann Arbor, MI, ³Radiology, University of Michigan, Ann Arbor, MI, ⁴Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, ⁵Rheumatology, University of Texas Medical School at Houston, Houston, TX, ⁶Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁷Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁸Dept of Medicine, Medical University of South Carolina, Charleston, SC, ⁹Division of Rheumatology, Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, ¹⁰University of Michigan, Ann Arbor, MI, ¹¹Rheumatology, Georgetown University Medical Center, Washington, DC, ¹²Div of Rheumatology, University of Utah, Salt Lake City, UT, ¹³Division of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Arthropathy and tendinopathy in Systemic Sclerosis (SSc) contribute to disability and are associated with disease progression. Clinical trials in SSc sometimes include the tender…
Abstract Number: 2962 • 2015 ACR/ARHP Annual Meeting
Efficacy of Mycophenolate As a Maintenance Therapy Following the Administration of Cyclophosphamide in the Treatment of Interstitial Lung Disease Associated with Systemic Sclerosis
Javier Narváez¹, Helena Borrell Paños², Ivan Castellvi³, Sergi Heredia², Milena Millan³, Susana Herrera⁴, Eulalia Armengol², Josep María LLobet³, Joan Miquel Nolla², María Molina⁵ and Juan José Alegre⁶, ¹Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ²Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Rheumatology Unit. Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ⁴Deparment of Pneumology, Hospital Universitario Dr Peset, Valencia, Spain, ⁵Department of Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁶Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain
Background/Purpose: Treatment with cyclophosphamide (CYC) for 12 months stabilizes lung function parameters and improves respiratory symptoms of patients with systemic sclerosis and diffuse interstitial lung…
Abstract Number: 2963 • 2015 ACR/ARHP Annual Meeting
Correlations Between Microvasculature Changes and Angiogenic Factors in Systemic Sclerosis – Data from a Single Center Registry
Radim Becvar¹, Simona Skacelova², Jiri Stork³, Hana Hulejová⁴, Ivana Putova⁵, Michal Tomcik⁶ and Marie Jachymova⁷, ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, ³Clinic of Dermatology and Venerology, Prague, Czech Republic, ⁴Institute of Rheumatology, Department of Rheumatology of the First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, ⁵Institute of Rheumatology and Department of Rheumatology of the 1st Faculty of Medicine, Charles University, Prague 2, Czech Republic, ⁶Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Prague, Czech Republic, ⁷Second Internal Clinic – Clinic of Cardiology and Angiology, General University Hospital,, Prague, Czech Republic
Background/Purpose: Histopathological hallmarks of systemic sclerosis (SSc) are perivascular infiltrates and a reduced capillary density, which precede the excessive accumulation of extracellular matrix components in…
Abstract Number: 2964 • 2015 ACR/ARHP Annual Meeting
Influences of Various Factors on Survival of Patients Treated with Pulmonary Arterial Hypertension-Specific Drugs Combination Therapy in Patients with Connective Tissue Diseases
Sumiaki Tanaka¹, Yu Matsueda², Eisuke Ogawa¹, Jun Okada³ and Shunsei Hirohata¹, ¹Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan, ²Rheumatology and Infectious diseases, Kitasato University School of Medicine, Kanagawa, Japan, ³Rheumatology, Kitasato University Hospital, Sagamihara, Japan
Background/Purpose: In patients with connective tissue disease (CTD), especially systemic sclerosis (SSc), several mechanisms have been implicated for the development of pulmonary hypertension (PH), including…
Abstract Number: 2965 • 2015 ACR/ARHP Annual Meeting
Might Troponin be a Marker for Subclinical Scleroderma Heart Involvement (SHI)?
Chiara Stagnaro¹, Anna d'Ascanio¹, Alice Parma², Umberto Conti³, Michele Emdin⁴, Alessandra Della Rossa¹ and Marta Mosca¹, ¹Internal Medicine, University of Pisa, Pisa, Italy, ²University of Pisa, Pisa, Italy, ³Cardiotoracico, Cardiologia 2, Pisa, Italy, ⁴Fondazione Toscana Gabriele Monasterio, UOC Cardiologia e Medicina Cardiovascolare, Pisa, Italy
Background/Purpose: Systemic sclerosis (SSc) is a rare connective tissue disease with pronounced alterations of the microvascular system, frequent cellular and humoral immunity abnormalities and fibroblast…
Abstract Number: 2966 • 2015 ACR/ARHP Annual Meeting
Pulmonary Involvement in Systemic Sclerosis at Initial Presentation: A Single Center Experience
Ranadeep Mandhadi¹ and Santhanam Lakshminarayanan², ¹Division of Rheumatology, The University of Connecticut Health Center, Farmington, CT, ²Division of Rheumatology, University of Connecticut Health Center, Farmington, CT
Background/Purpose: Systemic Sclerosis (SSc) is a rare heterogeneous autoimmune connective tissue disease.Pulmonary involvement is the major cause of mortality and morbidity in Systemic sclerosis. The…
Abstract Number: 2967 • 2015 ACR/ARHP Annual Meeting
Musculoskeletal Involvement in SSc Correlates with Poor Short Form 36 and SSc Health Assessment Questionnaire Scores As Well As Lower TNF-Alpha Gene Expression in PBMCs
Eliza Pelrine¹, Marie-Dominique Ah-Kioon¹, Meng Zhang², Franck J. Barrat³, Robert F. Spiera³ and Jessica K. Gordon³, ¹Hospital for Special Surgery, New York, NY, ²Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Systemic Sclerosis (SSc) is characterized by a wide variety of symptoms and disease manifestations including joint pain, gastrointestinal dysfunction, interstitial lung disease, and cardiomyopathy. …
Abstract Number: 2968 • 2015 ACR/ARHP Annual Meeting
Interrater Reliability of Nailfold Capillaroscopy in Systemic Sclerosis Using Widefield Microscopy
Jessica K. Gordon¹, Meng Zhang², Shervin Assassi³, Elana J. Bernstein⁴, Robyn T. Domsic⁵, Faye N. Hant⁶, Monique E. Hinchcliff⁷, Dinesh Khanna⁸, Ami A. Shah⁹, Victoria K. Shanmugam^10,11, Virginia D. Steen¹² and Tracy M. Frech¹³, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, ³Rheumatology, University of Texas Medical School at Houston, Houston, TX, ⁴Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁵Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁶Dept of Medicine, Medical University of South Carolina, Charleston, SC, ⁷Division of Rheumatology, Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, ⁸Division of Rheumatology, University of Michigan, Ann Arbor, MI, ⁹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁰Director, Division of Rheumatology, The George Washington University, Washington, DC, ¹¹Division of Rheumatology, The George Washington University, Washington, DC, ¹²Rheumatology, Georgetown University Medical Center, Washington, DC, ¹³Div of Rheumatology, University of Utah, Salt Lake City, UT
Background/Purpose: The presence of nailfold capillary (NFC) abnormality is part of the 2013 ACR/EULAR Classification Criteria for Systemic Sclerosis (SSc). NFC findings include the presence…
Abstract Number: 2969 • 2015 ACR/ARHP Annual Meeting
X-Ray Diffraction of Spontaneously Draining Calcinosis in Patients with Scleroderma
Vivien Hsu¹, Thomas Emge² and Naomi Schlesinger³, ¹Medicine, Rutgers University, New Brunswick, NJ, ²Dept of Chemistry and Chemical Biology, Rutgers- the State University, Piscataway, NJ, ³Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: Calcinosis is caused by deposition of calcified materials in the soft tissues (1). Hydroxyapatite (HA) is reported to be its major constituent (2). Mechanical…
Abstract Number: 2970 • 2015 ACR/ARHP Annual Meeting
Primary Care Assessment of Capillaroscopy Abnormalities in Patients with Raynaud’s Phenomenon
Rebecca Overbury¹, Maureen Murtaugh², Aryeh Fischer³ and Tracy M. Frech⁴, ¹Internal Medicine and Pediatrics, University of Utah, Salt Lake City, UT, ²Internal Medicine-Division of Epidemiology, University of Utah School of Medicine, SLC, UT, ³University of Colorado School of Medicine, Aurora, CO, ⁴Div of Rheumatology, University of Utah Medical Ctr, Salt Lake City, UT
Background/Purpose: Raynaud’s phenomenon is a clinical symptom that can commonly present to a primary care provider or generalist. Proper identification of an underlying connective tissue…
Abstract Number: 2971 • 2015 ACR/ARHP Annual Meeting
Raynaud Phenomenon Subjects with Abnormal Capillary Dilations Show a Risk Threshold Diameter Value for the Transition to the Capillaroscopic Early� Scleroderma Pattern: A Case Control Study
Maurizio Cutolo¹, Carmen Pizzorni², Marianna Meroni², Vanessa Smith³, Sabrina Paolino², Barbara Ruaro², Alberto Sulli², Bruno Seriolo² and Amelia Chiara Trombetta², ¹Department of Internal Medicine, University of Genova, Genova, Italy, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, ³Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium
Background/Purpose: Nailfold Video Capillaroscopy (NVC) is a reliable method to qualitatively differentiate Primary (PRP) from Secondary Raynaud Phenomenon (SRP) through diagnosis of the “early scleroderma…
Abstract Number: 2972 • 2015 ACR/ARHP Annual Meeting
Cardiopulmonary Exercise Testing in Patients with Systemic Sclerosis: Unexplored Mechanisms of Dyspnea
Sara R. Schoenfeld¹, George Alba², Josanna Rodriguez-Lopez³, Richard N. Channick³, Flavia V. Castelino⁴ and Marcy B. Bolster⁴, ¹Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Department of Pulmonary and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Pulmonary and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Patients with systemic sclerosis (SSc) experience dyspnea for multiple reasons. Cardiopulmonary exercise testing (CPET), an important tool in the evaluation of undifferentiated dyspnea, provides…
Abstract Number: 2973 • 2015 ACR/ARHP Annual Meeting
Exercise Intolerance Evaluated By Invasive Cardiopulmonary Exercise Testing in Connective Tissue Disease: Beyond Pulmonary Hypertension
Rudolf Oliveira^1,2, David Systrom², Julie Tracy², Abbey Karin², Aaron Waxman², Paul Dellaripa³ and Paul Hoover³, ¹Medicine, Division of Respiratory Disease, Federal University Of São Paulo, São Paulo, Brazil, ²Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, ³Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Exercise intolerance is common in patients with connective tissue disease (CTD) and may be related to pulmonary hypertension (PH). However, determining the exact etiology…

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