ACR Meeting Abstracts

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  • Abstract Number: 2435 • 2015 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Adult Juvenile Idiopathic Arthritis Patients Treated with Biologic Agents

    Katerina Jarosova1, Katerina Andelova2, Karel Hejduk3, Michal Uher3 and Jiri Vencovsky4, 1Institute of Rheumatology, Prague, Czech Republic, 2clinical, Institute for the Care for Mother and Child, Prague, Czech Republic, 3Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic, 4Institute of Rheumatology and Department of Rheumatology, Charles University, Prague, Czech Republic

    Background/Purpose: Biologic drugs are effective therapeutic option in patients with juvenile idiopathic arthritis (JIA). However, data regarding the use during pregnancy and breastfeeding in adult…
  • Abstract Number: 2436 • 2015 ACR/ARHP Annual Meeting

    Views and Prescribing Habits of Pneumocystis Prophylaxis in the Pediatric Rheumatology Community

    Matthew Basiaga1, Alexis Ogdie-Beatty2 and for the CARRA Investigators, 1Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Pneumocystis pneumonia (PCP) is a potentially devastating opportunistic infection.  The incidence of PCP and the risk of adverse events secondary to prophylactic medication in…
  • Abstract Number: 2437 • 2015 ACR/ARHP Annual Meeting

    Experience with Tocilizumab for Treatment of 56 Children with Systemic Juvenile Idiopathic Arthritis in the German JIA Biologics Register

    Gerd Horneff1, Gerd Ganser2, Johannes Peter Haas3, Toni Hospach4, Ralf Trauzeddel5, Hans-Iko Huppertz6, J B. Kuemmerle-Deschner7, Kirsten Minden8 and BIKER Registry Study Group, 1Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 2Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, 3German Centre for Rheumatology in Children and Young People, Garmisch-Partenkirchen, Germany, 4Pediatrics, Olgahospital, Klinikum Stuttgart, Stuttgard, Germany, 5HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, 6PRINTO, IRCCS G. Gaslini, Genoa, Italy, 7Pediatrics, University Hospital Tuebingen, Tuebingen, Germany, 8DRFG, Berlin, Germany

    Background/Purpose: Tocilizumab (TOC) has become a valuable option for treatment of systemic juvenile idiopathic arthritis (sJIA), which significantly improved the outcome of patients. The aim…
  • Abstract Number: 2438 • 2015 ACR/ARHP Annual Meeting

    Clinical Examination of the Temporomandibular Joint; A Eurotmjoint Initiative

    Bernd Koos1, Peter Stoustrup2, Lynn R. Spiegel3, Nikolay Tzaribachev4, Troels Herlin5, Thomas Klit Pedersen6 and Marinka Twilt7, 1Orthodontics, University of Rostock, Rostock, Germany, 2Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, 3Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, 4Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, 5Department of Pediatrics, Århus University Hospital Skejby, Århus, Denmark, 6orthodontics, Aarhus University Hospital/Dental school, Aarhus, Denmark, 7Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose: Arthritis of the temporomandibular joint (TMJ) in patients with Juvenile Idiopathic Arthritis (JIA) is increasingly recognized. In the last decade, studies report that the…
  • Abstract Number: 2439 • 2015 ACR/ARHP Annual Meeting

    Methotrexate Failure in Pediatric Uveitis

    Courtney McCracken1, Steven Yeh2, Kirsten Jenkins3, Daneka Stryker4, Steven Tommasello5, Curtis Travers1, Scott R. Lambert2, Carolyn Drews-Botsch6 and Sheila T. Angeles-Han1,2,3, 1Pediatrics, Emory University School of Medicine, Atlanta, GA, 2Ophthalmology, Emory University School of Medicine, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA, 4Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, 5University of Alabama, Birmingham, AL, 6Epidemiology, Emory University School of Public Health, Atlanta, GA

    Background/Purpose: Pediatric uveitis can lead to ocular complications and vision loss. Treatment consists of steroid drops, methotrexate (MTX), and anti-tumor necrosis factor (TNF) drugs.  Only…
  • Abstract Number: 2440 • 2015 ACR/ARHP Annual Meeting

    Using Patient-Relevant Variables to Describe the Disease Course in Children with Juvenile Idiopathic Arthritis

    Jaime Guzman1, Andrew Henrey2, Thomas Loughin2, Roberta Berard3, Natalie Shiff4, Roman Jurencak5, Susanne Benseler6, Lori B. Tucker7 and ReACCh-Out Investigators, 1Rheumatology, Division of Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, 2Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada, 3Children's Hospital of Western Ontario, London, ON, Canada, 4Pediatric Rheumatology, University of Saskatchewan, Saskatoon, SK, Canada, 5University of Ottawa, Ottawa, ON, Canada, 6Alberta Children's Hospital Research Institute/University of Calgary, Calgary, AB, Canada, 7Rheumatology, BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: To define distinct disease course groups among children with Juvenile Idiopathic Arthritis (JIA) based on observed changes in quality of life, pain, medication requirements,…
  • Abstract Number: 2441 • 2015 ACR/ARHP Annual Meeting

    Serum 14-3-3η Is Present in JIA and Is Not Associated with RF+ Polyarthritis

    Alan M. Rosenberg1, Walter Maksymowych2, Yuan Gui3 and Anthony Marotta3, 1Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, 2Department of Medicine, University of Alberta, Edmonton, AB, Canada, 3Augurex Life Sciences Corp., Vancouver, BC, Canada

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a collective term used to denote clinically discrete subtypes, which include: Enthesitis-related arthritis, Oligoarthritis, Polyarthritis, Psoriatic arthritis, Systemic arthritis…
  • Abstract Number: 2442 • 2015 ACR/ARHP Annual Meeting

    The Family Journey to Diagnosis with Systemic Juvenile Idiopathic Arthritis As Evidenced through Changing Social Media Presence

    Renee F Modica1, Kathleen G Lomax2, Pamela Batzel3, Leah Shapardanis3, Kimberly A Compton3 and Melissa E Elder4, 1UF Health Shands Children’s Hospital, Gainesville, FL, 2Medical Affairs, Immunology and Dermatology, Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3TREATO, Princeton, NJ, 4Pediatrics, Univ of Florida, Gainesville, FL

    Background/Purpose: Patients with systemic juvenile idiopathic arthritis (SJIA) frequently encounter delays from symptom onset to SJIA diagnosis (dx), partly due to the broad differential of…
  • Abstract Number: 2443 • 2015 ACR/ARHP Annual Meeting

    Pediatric Tele-Rheumatology: A Pilot Project to Assess Accuracy of Physical Examination Findings and Diagnostic Concordance at a Distance

    Michael Henrickson1, Jody Raugh2, Kelsey Hofacer3 and Adam Furnier4, 1Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Occupational and Physical Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Center for Telehealth, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Quality Improvement Systems, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Telemedicine (TM) offers a strategic means of extending limited clinical pediatric rheumatology (PR) workforce capacity to improve access to care for patients in remote…
  • Abstract Number: 2444 • 2015 ACR/ARHP Annual Meeting

    Accelerometer-Assessed Daily Physical Activity in Relation to Pain Cognitions and Quality of Life in Juvenile Idiopathic Arthritis

    Mette Noergaard1, Johanne Lomholt2, Mikael Thastum2, Morten Herlin3, Marinka Twilt4 and Troels Herlin4, 1Department of Physiotherapy, Aarhus University Hospital, Aarhus, Denmark, 2Psychology and Social Sciences, Aarhus University, Aarhus, Denmark, 3Pediatrics, Aarhus University Hospital, Aarhus, Denmark, 4Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) has been associated with decreased physical activity (PA). However, accurate, objective measurements of PA related to potential factors limiting PA…
  • Abstract Number: L25 • 2014 ACR/ARHP Annual Meeting

    Efficacy and Safety of Subcutaneous Tabalumab in Patients with Systemic Lupus Erythematosus (SLE): Results from 2 Phase 3, 52-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trials

    David A. Isenberg1, Murray B. Urowitz2, Joan T. Merrill3, Robert W. Hoffman4, Matthew D. Linnik4, MaryAnn Morgan-Cox4, Melissa F. Veenhuizen4, Noriko Iikuni4, Michelle Petri5 and ILLUMINATE-1 Investigators, 1University College London, London, United Kingdom, 2University of Toronto, Toronto Western Hospital, Toronto, ON, 3Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Eli Lilly and Company, Indianapolis, IN, 5Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: B-cell Activating Factor (BAFF) is a key regulator of B-cell development, survival, and activation. Tabalumab is a human IgG4 monoclonal antibody, administered subcutaneously, that binds…
  • Abstract Number: 3017 • 2014 ACR/ARHP Annual Meeting

    Program Evaluation of ‘the Joint Clinic’: An Innovative Clinical Service for Patients with Hip or Knee Osteoarthritis

    J. Haxby Abbott1, Helen Harcombe2, Chris Crane3, Liam Hutton3, Kirsten Stout3, Cathy Chapple4 and David Gwynne-Jones5, 1Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, 2Centre for Musculoskeletal Outcomes Research, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, 3Dunedin Hospital, Southern District Health Board, Dunedin, New Zealand, 4School of Physiotherapy, University of Otago, Dunedin, New Zealand, 5Orthopaedic Surgery, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand

    Background/Purpose: In socialized healthcare systems with free public access to healthcare, there are circumstances wherein patients referred by general medical practitioners (GPs) for specialist physician…
  • Abstract Number: 3018 • 2014 ACR/ARHP Annual Meeting

    Testing of a Newly Developed Computerized Animated Activity Questionnaire  for Assessing Activity Limitations in Patients with Hip and Knee Osteoarthritis

    Wilfred FH Peter1, Mick Loos2, Henrica de Vet3, Maarten Boers3, Jaap Harlaar4, Leo D. Roorda5, Rudolf Poolman6, Vanessa Scholtes6, Jan Bogaard7, Hilda Buitelaar1, Martijn P.M. Steultjens8, Ewa M. Roos9, Anne-Christine Rat10, Francis Guillemin11, Maria Grazia Benedetti12, Antonio Escobar Martinez13, Nina Østerås14 and Caroline Terwee3, 1Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 2Epidemiology and Biostatistics and the EMGO Institute for Health and Care research, VU University Medical Center, Amsterdam, Netherlands, 3Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 4Dep of Rehabilitation Medicine and MOVE research institute, VU University Medical Center, Amsterdam, Netherlands, 5Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, 6Department of Orthopedics, Joint Research, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands, 7Dep of Epidemiology and Biostatistics and the EMGO Institute for Health and Care research, VU University Medical Center, Amsterdam, Netherlands, 8Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, 9Inst Sports and Biomechanics, University of Southern Denmark, Odense, Denmark, 10University Paris Descartes, EA 4360 APEMAC, University of Lorraine, Nancy, France, 11INSERM, Centre d'Investigation Clinique - Epidémiologie Clinique (CIC-EC) CIE6, Nancy, France, 12Physical Medicine and Rehabilitation Unit, Istituto Ortopedico Rizzoli, Bologna, Italy, 13Health Service Research Network on Chronic Diseases (REDISSEC), Basurto University Hospital, Bilbao, Spain, 14Department of rheumatology, National Advisory Unit for rehabilitation in rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose Self-report questionnaires and performance-based tests correlate moderately in measuring activity limitations, indicating that they measure different aspects. Self-reports measure mainly how patients think they…
  • Abstract Number: 2997 • 2014 ACR/ARHP Annual Meeting

    Development and External Validation of a Five-Year Mortality Risk Stratification Tool for Early Diffuse Systemic Sclerosis Patients

    Robyn T. Domsic1, Svetlana I. Nihtyanova2, Mary Lucas3, Stephen R. Wisniewski4, Michael J. Fine5, C. Kent Kwoh6, Christopher P. Denton7 and Thomas A. Medsger Jr.8, 1Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, 2Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, 3Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, 5General Medicine, University of Pittsburgh and Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare, Pittsburgh, PA, 61501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ, 7Centre for Rheumatology, Royal Free and University College Medical School, London, United Kingdom, 8Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose : Knowledge of mortality risk and predictors is important in systemic sclerosis (SSc) patient care and clinical trial design.   There is no validated 5-year…
  • Abstract Number: 2998 • 2014 ACR/ARHP Annual Meeting

    Screening for Interstitial Lung Disease in Systemic Sclerosis: Performance of High-Resolution Computed Tomography with Limited Number of Slices – a Prospective Study

    Thomas Frauenfelder1, Anna Winklehner1, Thi Dan Linh Nguyen1, Rucsandra Dobrota2,3, Stephan Baumüller1, Britta Maurer2 and Oliver Distler2, 1Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, 2Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 3Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Background/Purpose Early diagnosis of interstitial lung disease (ILD), currently the main cause of death in systemic sclerosis (SSc), is needed. The gold standard is high…
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