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  • Abstract Number: 2405 • 2015 ACR/ARHP Annual Meeting

    Knee Sounds May Predict Osteoarthritis Severity, Symptoms and Function: Pilot Investigation Toward a Novel Dynamic Imaging System

    Victoria Manning1, Costas Yiallourides2, Mads Brevadt1, Alastair Moore2, Edouard Auvinet1, Patrick Naylor2 and Justin Cobb1, 1Musculoskeletal Lab, Imperial College London, London, United Kingdom, 2Communications and Signal Processing Group, Imperial College London, London, United Kingdom

    Background/Purpose: Knee sounds (KS) may provide a low-cost, risk-free means of identifying presence and severity of knee osteoarthritis (KOA). Unlike static imaging, KS during dynamic…
  • Abstract Number: 2406 • 2015 ACR/ARHP Annual Meeting

    The 2011 Fibromyalgia (FM) Criteria Are Helpful in Identifying Central Sensitization in Knee Osteoarthritis

    Steven E. Harte1, Andrew D. Clauw1, J. Ryan Scott1, Daniel J. Clauw2 and Chad Brummett2, 1Department of Anesthesiology, University of Michigan, Ann Arbor, MI, 2Anesthesiology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Both animal and human studies have suggested that both peripheral and central sensitization may occur in nociceptive pain states such as OA.  This distinction…
  • Abstract Number: 2407 • 2015 ACR/ARHP Annual Meeting

    Comparison of Knee Osteoarthritis Treatment in the Non-Obese Versus Obese Populations Across Different Medical Specialties

    Kelly Forrester1, Farah Taufiq1 and Jonathan Samuels2,3, 1NYU Langone Medical Center, New York, NY, 2Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, 3Rheumatology, NYU Langone Medical Center, New York, NY

    Background/Purpose:   Knee osteoarthritis (KOA) in the obese population is underdiagnosed and routinely undertreated, as providers often attribute pain to excess weight without considering articular…
  • Abstract Number: 2408 • 2015 ACR/ARHP Annual Meeting

    The Quality of Community-Based Osteoarthritis Care Can be Improved. Results from a Systematic Review and Meta-Analysis

    Kåre Birger Hagen1, Geir Smedslund2, Nina Østerås2 and Gro Jamtvedt3, 1National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology,, Diakonhjemmet Hospital, Oslo, Norway, 3The Norwegian Knowledge Center for the Health Services, Oslo, Norway

    Background/Purpose: The burden of osteoarthritis (OA) is substantial and expected to increase because people are getting older and heavier. Health care providers need to monitor…
  • Abstract Number: 2409 • 2015 ACR/ARHP Annual Meeting

    Factors Associated with Physical Therapy Use in Osteoarthritis of the Knee: Results from a Population-Based Study

    Sicong Huang1, Eric C. Sayre2 and Jolanda Cibere1,2, 1Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Canada, Richmond, BC, Canada

    Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis. Physical therapy (PT) has previously been demonstrated to benefit patients with osteoarthritis, especially with early…
  • Abstract Number: 2410 • 2015 ACR/ARHP Annual Meeting

    Report from the International Consortium of Health Outcome Measurement Hip and Knee Osteoarthritis Working Group: Consensus on an International Standard Set of Outcomes Measures for Patients with Hip or Knee Osteoarthritis.

    Philip G. Conaghan1, Lyn March2, Ola Rolfson3, Stephanie Wissig4, Caleb Stowell5, Patricia D. Franklin6 and The ICHOM Working Group in Hip & Knee Osteoarthritis, 1University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 2Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, 3Harris Orthopaedic Laboratory, Massachusetts General Hospital, Harvard Medical School,, International Consortium for Health Outcomes Measurement, Boston, MA, 4ICHOM, International Consortium for Health Outcomes Measurement, Cambridge, MA, 514 Arrow St., Ste. #11, 3International Consortium for Health Outcomes Measurement, Cambridge, MA, 6Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA

    Background/Purpose: To define a minimum Standard Set of outcome measures and case-mix factors for monitoring, comparing, and improving healthcare for patients with clinically diagnosed hip…
  • Abstract Number: 2411 • 2015 ACR/ARHP Annual Meeting

    Patient Preference for Using Technology to Track and Self-Manage Osteoarthritis

    Laura Khurana, Ellen Durand, Sarah Gary, Tony Otero, Chris Hall and Susan Dallabrida, ERT, Boston, MA

    Background/Purpose: Active and consistent self-management is essential for patients suffering from chronic diseases to improve their health.  Electronic clinical (eClinical) technology may improve how patients…
  • Abstract Number: 2412 • 2015 ACR/ARHP Annual Meeting

    Assessment and Comparison of Responsiveness of Four Patient Reported Outcome Measures to Assess Physical Function in Patients with Knee Osteoarthritis: WOMAC-PF Subscale Responds Best

    Elien A.M. Mahler1, Nienke Cuperus2, Johannes W J Bijlsma3, Thea Vliet Vlieland4, Frank H.J. van den Hoogen5, Alfons den Broeder5 and Cornelia H.M. van den Ende1, 1Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 2Rheumatology Department, Sint Maartenskliniek, Nijmegen, Netherlands, 3Rheumatology and Clinical Immunology, ARC Amsterdam; UMC Utrecht, Utrecht, Netherlands, 4Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands

    Background/Purpose: Although physical function is one of the core outcome domains in knee osteoarthritis (OA), the ability of a measurement instrument to detect changes over…
  • Abstract Number: 2413 • 2015 ACR/ARHP Annual Meeting

    Contributors to Walking Disability in People with Osteoarthritis: Results from a Population-Based Cohort

    Lauren King1, Tetyana Kendzerska1,2,3 and Gillian Hawker1,2,3, 1Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, 3Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Osteoarthritis (OA) is associated with functional limitations, including difficulty walking. However, comorbid disease is common in people with OA and may also be associated…
  • Abstract Number: 2414 • 2015 ACR/ARHP Annual Meeting

    High-Intensity Versus Low-Intensity Physical Activity or Exercises in Patients with Hip or Knee Osteoarthritis: A Meta-Analysis

    Jean-Philippe Regnaux1,2,3, Marie-Martine Lefèvre-Colau4, Ludovic Trinquart3, Christelle Nguyen5, Isabelle Boutron1,3,6,7, Lucie Brosseau8 and Philippe Ravaud3,6,7,9, 1METHODS team, INSERM UMR-S 1153, Paris, France, 2EHESP Rennes, Sorbonne Paris Cité, Paris, France, 3French Cochrane Center, Paris, France, 4Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de rééducation et réadaptation de l’appareil locomoteur et des pathologies du rachis, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, 5Univ. Paris Descartes, PRES Sorbonne Paris, Cité Laboratoire de Pharmacologie, Toxicologie et Signalisation Cellulaire, INSERM UMR-S 1124, UFR Biomédicale des Saints Pères, Paris, France, Paris, France, 6Paris Descartes University, Sorbonne Paris Cité, Faculté de Médecine, Paris, France, 7Centre d’Épidémiologie Clinique, AP-HP (Assistance Publique des Hôpitaux de Paris), Hôpital Hôtel Dieu, Paris, France, 8Rehabilitation Sciences, University of Ottawa, Ottawa, ON, Canada, 9METHODS team, INSERM U1153, Paris, France

    Background/Purpose: Exercise or physical activity are complex interventions whose effectiveness depends on more than one component. We aimed to determine the benefits and harms of…
  • Abstract Number: 2415 • 2015 ACR/ARHP Annual Meeting

    Use of Plasma Exchange for Children Hospitalized with ANCA-Associated Vasculitis in the United States

    Karen James1, Rui Xiao2, Peter A. Merkel3 and Pamela F. Weiss1, 1Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 3Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: ANCA-associated vasculitis (AAV) is a group of rare systemic vasculitidies with significant morbidity and mortality. Plasma exchange (PLEX) has been shown to decrease risk…
  • Abstract Number: 2416 • 2015 ACR/ARHP Annual Meeting

    Pharmacokinetics, Safety, and Tolerability of Tofacitinib in Pediatric Patients from Six to Less Than Eighteen Years of Age with Juvenile Idiopathic Arthritis

    Hermine I. Brunner1, Nicolino Ruperto2, Nikolay Tzaribachev3, Zbigniew Zuber4, Elena Koskova5, Ivan Foeldvari6, Eizbieta Smolewska7, Gerd Horneff8, Charles Mebus9, Umberto Conte10, Rong Wang9, Christine Alvey9, Manisha Lamba9, Anasuya Hazra11, Daniel Lovell12 and Alberto Martini13, 1Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Istituto G. Gaslini, Pediatria II, PRINTO, Genoa, Italy, 3Pediatric Rheumatology, Bad Bramstedt, Germany, 4St Louis Children’s Hospital ODS Rheumatology and Neurology, Krakow, Poland, 5Institute of Rheumatic Diseases, Piestany, Slovakia, 6Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, 7Department of Pediatric Cardiology and Rheumatology, Medical University of Lodz, Lodz, Poland, 8Asklepios Klinik Sankt Augustin GmbH, Sankt Augustin, Germany, 9Pfizer Inc, Groton, CT, 10Pfizer Inc, New York, NY, 11Pfizer Inc, Collegeville, PA, 12Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 13Istituto G. Gaslini, Pediatria II, PRINTO, and University of Genoa, Genoa, Italy

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of adult patients with rheumatoid arthritis (RA). We report the pharmacokinetics (PK), safety and…
  • Abstract Number: 2417 • 2015 ACR/ARHP Annual Meeting

    Induction and Maintenance of Remission By Etanercept in Enthesitis Related Arthritis JIA-Patients

    Gerd Horneff1, Ivan Foeldvari2, Kirsten Minden3, Ralf Trauzeddel4, J B. Kuemmerle-Deschner5, Klaus Tenbrock6, Gerd Ganser7 and Hans-Iko Huppertz8, 1Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 2Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, 3DRFG, Berlin, Germany, 4HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, 5Pediatrics, University Hospital Tuebingen, Tuebingen, Germany, 6University Aachen, Aachen, Germany, 7Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, 8PRINTO, IRCCS G. Gaslini, Genoa, Italy

    Background/Purpose: Enthesitis-related arthritis (ERA) is a juvenile idiopathic arthritis (JIA) category affecting entheses and joints. The REMINDER study to analyse the efficacy of etanercept (ETA)…
  • Abstract Number: 2418 • 2015 ACR/ARHP Annual Meeting

    Pediatric Enthesitis-Related Arthritis: Variation in Disease Characteristics and Treatments Among 5 Large Centers

    Sabrina Gmuca1, Timothy Brandon2, Rui Xiao3, Ilaria Pagnini4, Tracey B. Wright5, Timothy Beukelman6, Esi Morgan-DeWitt7 and Pamela F. Weiss8, 1Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, 3Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 4Department of Paediatrics, University of Florence and Anna Meyer Children's Hospital, Florence, Italy, Florence, Italy, 5Pediatrics/Rheumatology, Univ of TX Southwestern, Dallas, TX, 6Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 7Pediatric rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 8Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: We aimed to compare the clinical features and treatments of children with Enthesitis-related arthritis (ERA) from 5 pediatric rheumatology centers in order to determine…
  • Abstract Number: 2419 • 2015 ACR/ARHP Annual Meeting

    Safety and Efficacy of Etanercept in 2000 Patients with Juvenile Idiopathic Arthritis (JIA) in the JIA Biologics Register

    Gerd Horneff1, Juergen Brunner2, Johannes Peter Haas3, Gerd Ganser4, Ivan Foeldvari5, Toni Hospach6, Kirsten Minden7, Hans-Iko Huppertz8, Rolf M. Kuester9, Ralf Trauzeddel10, Angelika Thon11 and BIKER Study Group, 1Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 2Universitätsklinik für Kinder- u. Jugendheilkunde, Innsbruck, Austria, 3German Centre for Rheumatology in Children and Young People, Garmisch-Partenkirchen, Germany, 4Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, 5Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, 6Pediatrics, Olgahospital, Klinikum Stuttgart, Stuttgard, Germany, 7DRFG, Berlin, Germany, 8PRINTO, IRCCS G. Gaslini, Genoa, Italy, 9Asklepios Rheumazentrum Hamburg, Hamburg, Germany, 10HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, 11Department of Pediatrics, Hannover, Germany

    Background/Purpose: Treatment with Etanercept (ETA) was followed prospectively. The purpose of this interim analysis is to evaluate efficacy/ safety of ETA in routine care settings.…
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